9 results on '"Chamolly, Alexander"'
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2. Propulsion, navigation and control of biological and artificial microswimmers
- Author
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Chamolly, Alexander and Lauga, Eric
- Subjects
Fluid Dynamics ,Biological Physics ,Soft Matter - Abstract
This dissertation contains original research on a range of problems involving the locomotion of different types of microswimmers, including both biological microorganisms and artificial colloids. Due to the physical constraints imposed by the inertialess hydrodynamics at these small scales, these swimmers rely on multiple locomotion strategies that are unfamiliar from the macroscale. The results presented here answer several theoretical questions concerning the fundamentals of specific propulsion mechanisms, as well as the interactions of a wide range of different microswimmers with geometrically complex environments. For a general spherical squirmer-type microswimmer we first analyse the swimming dynamics in a periodic three-dimensional lattice of obstacles numerically, and obtain a phase diagram detailing qualitatively different kinds of trajectories. These range from nearly straight over diffusive to trapped, depending on the squirming parameter and the lattice packing density. We then explain these results theoretically using a combination of near- and far-field hydrodynamic arguments. Importantly, we predict qualitatively different dynamics of `pusher'-type swimmers, such as bacteria, and `puller'-type swimmers, such as algae, in a geometry that is representative for soil as a biologically relevant domain. Next, we derive the singularity representation for the solution of the Stokes equations in the two cases of a point torque outside a rigid sphere, and a point torque outside a spherical bubble. In the axisymmetric case outside a rigid sphere, the solution takes an extremely simple form that is reminiscent of the solution for a point charge outside a grounded sphere in electrostatics, and is rationalised with a similar geometrical argument. In addition, we repeat the analysis for a point source. We apply these results to an analysis of the swimming dynamics of a single peritrichous bacterium, specifically the physical mechanisms that lead to the formation of a flagellar bundle behind the cell during its forward motion. We categorise the forces at play into `direct' and `indirect' depending on whether they are due to hydrodynamic interactions between the flagellar filaments, or triggered by flows around the cell body due to its motion, and demonstrate using a minimal theoretical model that under very general conditions the latter dominate in all but the final stages of bundle formation. For parameter values that are representative for the model bacterium Escherichia Coli we perform a full dynamic elastohydrodynamic simulation to analyse the relative strength of hydrodynamic and elastic effects along the full length of the flagella during the bundling process. On the topic of artificial microswimmers we next examine theoretically the stochastic dynamics of a self-propelled colloid that is dissolving over time, as motivated by recent experiments aimed at the design of active particles suitable for biomedical applications. We present two models that differ in the details of the dissolution mechanism, and in each case derive analytical expressions for the particle life time and mean squared displacement due to active diffusion. A new dimensionless parameter emerges, classifying trajectories into globally ballistic and globally diffusive depending on the ratio of particle life time to rotational diffusivity, and we obtain a hierarchy of our models in all regimes that quantifies the limit of control that can be exerted on the motion of dissolving colloids. Expanding on the topic of control and manipulation on the microscale, we finally analyse the entrapment of passive cargo by a magnetically actuated spheroidal roller near a rigid wall. We predict that as such a roller propels along an interface, it is able to collect and transport passive cargo particles in its path by entrapping them inside a vortex to its side. This apparent violation of the Stokes flow reversibility is facilitated through irreversible steric interactions between the cargo and the interface, and analogous to the microfluidic technique of deterministic lateral displacement. We combine finite element simulations of the flow field due to the roller with an effective model for cargo migration to generate a phase diagram of entrapment as a function of roller aspect ratio, cargo size and cargo location, and predict that flat rollers are able to trap cargo for the largest range of parameter values.
- Published
- 2020
- Full Text
- View/download PDF
3. The Sphericity Paradox and the Role of Hoop Stresses in Free Subduction on a Sphere.
- Author
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Chaillat, Stéphanie, Gerardi, Gianluca, Li, Yida, Chamolly, Alexander, Li, Zhong‐Hai, and Ribe, Neil M.
- Subjects
STRAINS & stresses (Mechanics) ,SLABS (Structural geology) ,PLATE tectonics ,SUBDUCTION zones ,CONVEX geometry ,SUBDUCTION - Abstract
Oceanic plates are doubly curved spherical shells, which influences how they respond to loading during subduction. Here we study a viscous fluid model for gravity‐driven subduction of a shell comprising a spherical plate and an attached slab. The shell is 100–1,000 times more viscous than the upper mantle. We use the boundary‐element method to solve for the flow. Solutions of an axisymmetric model show that the effect of sphericity on the flexure of shells is greater for smaller shells that are more nearly flat (the "sphericity paradox"). Both axisymmetric and three‐dimensional models predict that the deviatoric membrane stress in the slab should be dominated by the longitudinal normal stress (hoop stress), which is typically about twice as large as the downdip stress and of opposite sign. Our models also predict that concave‐landward slabs can exhibit both compressive and tensile hoop stress depending on the depth, whereas the hoop stress in convex slabs is always compressive. We test these two predictions against slab shape and earthquake focal mechanism data from the Mariana subduction zone, assuming that the deviatoric stress in our flow models corresponds to that implied by centroid moment tensors. The magnitude of the hoop stress exceeds that of the downdip stress for about half the earthquakes surveyed, partially verifying our first prediction. Our second prediction is supported by the near‐absence of earthquakes under tensile hoop stress in the portion of the slab having convex geometry. Plain Language Summary: Tectonic plates on earth are doubly curved spherical shells, which influences how they respond to applied forces during subduction. We use axisymmetric and three‐dimensional viscous flow models to study the dynamics of spherical shells sinking under gravity into the mantle below. We find the surprising result that the effect of spherical geometry on the bending of shells is greater for smaller shells that are more nearly flat, which we call the "sphericity paradox." We also find that the stress in the subducted portions of plates ("slabs") is dominated by the longitudinal normal stress (hoop stress), which is about twice as large as the more familiar downdip stress. Earthquake focal mechanisms from the Mariana subduction zone in the Pacific ocean confirm our prediction that no deep earthquakes should occur under tensile hoop stress in portions of slabs having convex landward geometry. Key Points: The dynamical effect of plate sphericity on subduction is greater for smaller plates (the "sphericity paradox")The state of stress in the central portions of subducted slabs is dominated by the longitudinal normal (hoop) stressMariana slab earthquakes confirm our prediction that convex slab geometry and tensile hoop stress never occur together [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
4. Colloidal bubble propulsion mediated through viscous flows.
- Author
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Chamolly, Alexander, Michelin, Sébastien, and Lauga, Eric
- Published
- 2024
- Full Text
- View/download PDF
5. Irreversible hydrodynamic trapping by surface rollers.
- Author
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Chamolly, Alexander, Lauga, Eric, and Tottori, Soichiro
- Published
- 2020
- Full Text
- View/download PDF
6. Active particles in periodic lattices.
- Author
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Chamolly, Alexander, Takuji Ishikawa, and Lauga, Eric
- Subjects
- *
LATTICE constants , *REYNOLDS number , *PHASE diagrams , *SIMULATION methods & models , *HYDRODYNAMICS - Abstract
Both natural and artificial small-scale swimmers may often self-propel in environments subject to complex geometrical constraints. While most past theoretical work on low-Reynolds number locomotion addressed idealised geometrical situations, not much is known on the motion of swimmers in heterogeneous environments. As a first theoretical model, we investigate numerically the behaviour of a single spherical micro-swimmer located in an infinite, periodic body-centred cubic lattice consisting of rigid inert spheres of the same size as the swimmer. Running a large number of simulations we uncover the phase diagram of possible trajectories as a function of the strength of the swimming actuation and the packing density of the lattice. We then use hydrodynamic theory to rationalise our computational results and show in particular how the far-field nature of the swimmer (pusher versus puller) governs even the behaviour at high volume fractions. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
7. Stochastic dynamics of dissolving active particles.
- Author
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Chamolly, Alexander and Lauga, Eric
- Subjects
- *
MONTE Carlo method , *CHEMICAL models , *NANOPARTICLES , *COLLOIDS , *CHEMICAL reactions , *PARTICLE dynamics , *NANOCARRIERS - Abstract
The design of artificial microswimmers has generated significant research interest in recent years, for promise in applications such as nanomotors and targeted drug-delivery. However, many current designs suffer from a common problem, namely the swimmers remain in the fluid indefinitely, posing risks of clogging and damage. Inspired by recently proposed experimental designs, we investigate mathematically the dynamics of degradable active particles. We develop and compare two distinct chemical models for the decay of a swimmer, taking into account the material composition and nature of the chemical or enzymatic reaction at its surface. These include a model for dissolution without a reaction, as well as models for a reacting swimmer studied in the limit of large and small Damköhler number. A new dimensionless parameter emerges that allows the classification of colloids into ballistic and diffusive type. Using this parameter, we perform an asymptotic analysis to derive expressions for colloid lifetimes and their total mean squared displacement from release and validate these by numerical Monte Carlo simulations of the associated Langevin dynamics. Supported by general scaling relationships, our theoretical results provide new insight into the experimental applicability of a wide range of designs for degradable active colloids. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
8. Active particles in periodic lattices
- Author
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Eric Lauga, Alexander Chamolly, Takuji Ishikawa, Chamolly, Alexander [0000-0002-2383-9314], Lauga, Eric Lauga [0000-0002-8916-2545], and Apollo - University of Cambridge Repository
- Subjects
complex environment ,Stokesian dynamics ,General Physics and Astronomy ,FOS: Physical sciences ,Condensed Matter - Soft Condensed Matter ,01 natural sciences ,010305 fluids & plasmas ,Quantitative Biology::Cell Behavior ,lubrication theory ,Lattice (order) ,0103 physical sciences ,Physics - Biological Physics ,010306 general physics ,Phase diagram ,Physics ,Physics::Biological Physics ,Active particles ,Fluid Dynamics (physics.flu-dyn) ,Mechanics ,Physics - Fluid Dynamics ,Lubrication theory ,low-Reynolds number locomotion ,Sphere packing ,active particles ,Biological Physics (physics.bio-ph) ,Soft Condensed Matter (cond-mat.soft) ,SPHERES ,Hydrodynamic theory - Abstract
Both natural and artificial small-scale swimmers may often self-propel in environments subject to complex geometrical constraints. While most past theoretical work on low-Reynolds number locomotion addressed idealised geometrical situations, not much is known on the motion of swimmers in heterogeneous environments. As a first theoretical model, we investigate numerically the behaviour of a single spherical micro-swimmer located in an infinite, periodic body-centred cubic lattice consisting of rigid inert spheres of the same size as the swimmer. Running a large number of simulations we uncover the phase diagram of possible trajectories as a function of the strength of the swimming actuation and the packing density of the lattice. We then use hydrodynamic theory to rationalise our computational results and show in particular how the far-field nature of the swimmer (pusher versus puller) governs even the behaviour at high volume fractions.
- Full Text
- View/download PDF
9. Controlling Confined Collective Organization with Taxis.
- Author
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Théry A, Chamolly A, and Lauga E
- Abstract
Biased locomotion is a common feature of microorganisms, but little is known about its impact on self-organization. Inspired by recent experiments showing a transition to large-scale flows, we study theoretically the dynamics of magnetotactic bacteria confined to a drop. We reveal two symmetry-breaking mechanisms (one local chiral and one global achiral) leading to self-organization into global vortices and a net torque exerted on the drop. The collective behavior is ultimately controlled by the swimmers' microscopic chirality and, strikingly, the system can exhibit oscillations and memorylike features.
- Published
- 2024
- Full Text
- View/download PDF
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