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Your search keyword '"Carcinoma, Merkel Cell genetics"' showing total 289 results

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289 results on '"Carcinoma, Merkel Cell genetics"'

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1. Whole genome sequencing elucidates etiological differences in MCPyV-negative Merkel cell carcinoma.

2. Exploring the effects of Merkel cell polyomavirus T antigens expression in REH and MCC13 cells by methylome and transcriptome profiling.

3. Biomarker Analyses Investigating Disease Biology and Associations with Outcomes in the JAVELIN Merkel 200 Trial of Avelumab in Metastatic Merkel Cell Carcinoma.

4. Circulating Tumor DNA Assay Detects Merkel Cell Carcinoma Recurrence, Disease Progression, and Minimal Residual Disease: Surveillance and Prognostic Implications.

5. Merkel Cell Polyomavirus-Pathophysiology and Treatment in the Era of Gene-Targeted Therapies.

6. Analyses of combined Merkel cell carcinomas with neuroblastic components suggests that loss of T antigen expression in Merkel cell carcinoma may result in cell cycle arrest and neuroblastic transdifferentiation.

7. Genomic profiles of Merkel cell carcinoma in Japan.

8. The Role of the Large T Antigen in the Molecular Pathogenesis of Merkel Cell Carcinoma.

9. Polyomavirus ALTOs, but not MTs, downregulate viral early gene expression by activating the NF-κB pathway.

10. Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1.

11. Searching for biomarkers to help distinguish Merkel cell carcinoma from cutaneous small cell lung cancer with gene expression analysis.

12. Enhancer of Zeste Homolog 2 Inhibition Induces HLA Class I Re-Expression in Merkel Cell Carcinoma.

13. LT and SOX9 expression are associated with gene sets that distinguish Merkel cell polyomavirus (MCPyV)-positive and MCPyV-negative Merkel cell carcinoma.

14. Knockdown of nicotinamide N-methyltransferase suppresses proliferation, migration, and chemoresistance of Merkel cell carcinoma cells in vitro.

16. Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade.

17. Genetic Risk Factors for Early-Onset Merkel Cell Carcinoma.

18. T antigen-specific CD8+ T cells associate with PD-1 blockade response in virus-positive Merkel cell carcinoma.

19. Tumor cell-intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling.

20. Membrane-bound Merkel cell polyomavirus middle T protein constitutively activates PLCγ1 signaling through Src-family kinases.

21. A rare case of Merkel cell carcinoma on the craniofacial region and characterization of its aneuploid CD31 - CTCs and CD31 + CTECs expressing EpCAM or Ki-67.

22. Longitudinal multi-functional analysis identified responses of T cells, B cells, and monocytes as hallmarks of immunotherapy tolerance in patients with merkel cell carcinoma.

23. Biomaterial-Mediated Genetic Reprogramming of Merkel Cell Carcinoma and Melanoma Leads to Targeted Cancer Cell Killing In Vitro and In Vivo .

24. The emerging role of miRNAs in Merkel cell carcinoma pathogenesis: Signaling pathway crosstalk.

25. miRNAs driving diagnosis, prognosis and progression in Merkel cell carcinoma.

26. The HDAC inhibitor domatinostat induces type I interferon α in Merkel cell carcinoma by HES1 repression.

27. Characterization of molecular mechanisms driving Merkel cell polyomavirus oncogene transcription and tumorigenic potential.

28. Expression of Genes Associated With Epithelial-Mesenchymal Transition in Merkel Cell Polyomavirus-Negative Merkel Cell Carcinoma.

29. Single-cell dissection of Merkel cell carcinoma heterogeneity unveils transcriptomic plasticity and therapeutic vulnerabilities.

30. B-cell lymphoma-extra large is a promising drug target in Merkel cell carcinoma.

31. From genetic characterization to new potential therapeutic options: targeting Bcl-xL in Merkel carcinoma.

32. BRCA1/2 Pathogenic Variants Are Not Common in Merkel Cell Carcinoma: Comprehensive Molecular Study of 30 Cases and Meta-Analysis of the Literature.

33. Distinct retinoic gene signatures discriminate Merkel cell polyomavirus-positive from -negative Merkel cell carcinoma cells.

34. Transcriptomic analyses reveal three distinct molecular subgroups of Merkel cell carcinoma with differing prognoses.

35. HLA-G expression in Merkel cell carcinoma and the correlation with Merkel cell polyomavirus infection.

36. YAP1 and WWTR1 expression inversely correlates with neuroendocrine markers in Merkel cell carcinoma.

37. Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain.

38. Genomic Alterations and Tumor Mutation Burden in Merkel Cell Carcinoma.

39. Genomic integration and expression of Felis catus papillomavirus type 2 oncogenes in feline Merkel cell carcinoma.

41. MicroRNA dysregulations in Merkel cell carcinoma: Molecular mechanisms and clinical applications.

42. TRK Protein Expression in Merkel Cell Carcinoma Is Not Caused by NTRK Fusions.

43. Oncogenic Merkel Cell Polyomavirus T Antigen Truncating Mutations are Mediated by APOBEC3 Activity in Merkel Cell Carcinoma.

44. Merkel Cell Carcinoma Sensitivity to EZH2 Inhibition Is Mediated by SIX1 Derepression.

45. Transcriptional and functional analyses of neoantigen-specific CD4 T cells during a profound response to anti-PD-L1 in metastatic Merkel cell carcinoma.

46. The differential expression of long interspersed nuclear elements-1 as a marker for hypomethylation in Merkel cell carcinoma.

47. Milademetan is a highly potent MDM2 inhibitor in Merkel cell carcinoma.

48. Addiction of Merkel cell carcinoma to MUC1-C identifies a potential new target for treatment.

49. Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma.

50. Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice.

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