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20,980 results on '"CHEN, CHUN"'

7. Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan

Author

Chang, Chin-Wei, Hsu, Wei-Fan, Tseng, Kuo-Chih, Chen, Chi-Yi, Cheng, Pin-Nan, Hung, Chao-Hung, Lo, Ching-Chu, Bair, Ming-Jong, Chen, Chien-Hung, Lee, Pei-Lun, Lin, Chun-Yen, Kuo, Hsing-Tao, Chen, Chun-Ting, Yang, Chi-Chieh, Huang, Jee-Fu, Tai, Chi-Ming, Hu, Jui-Ting, Lin, Chih-Lang, Su, Wei-Wen, Tsai, Wei-Lun, Huang, Yi-Hsiang, Cheng, Chien-Yu, Lin, Chih-Lin, Wang, Chia-Chi, Yang, Sheng-Shun, Mo, Lein-Ray, Chen, Guei-Ying, Chang, Chun-Chao, Wang, Szu-Jen, Huang, Chia-Sheng, Hsieh, Tsai-Yuan, Lin, Chih-Wen, Lee, Tzong-Hsi, Chong, Lee-Won, Huang, Chien-Wei, Chang, Shiuh-Nan, Tsai, Ming-Chang, Hsu, Shih-Jer, Kao, Jia-Horng, Liu, Chun-Jen, Liu, Chen-Hua, Lin, Han-Chieh, Tsai, Pei-Chien, Yeh, Ming-Lun, Huang, Chung-Feng, Dai, Chia-Yen, Chuang, Wan-Long, Yu, Ming-Lung, and Peng, Cheng-Yuan

Published
2024
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11. Mutual-Aid Mobile App for Emergency Care: Feasibility Study

Author

Chien, Shuo-Chen, Islam, Md Mohaimenul, Yeh, Chen-An, Chien, Po-Han, Chen, Chun You, Chin, Yen-Po, and Lin, Ming-Chin

Subjects
Medicine
Abstract

BackgroundImproving the quality of patient care through the use of mobile devices is one of the hot topics in the health care field. In unwanted situations like an accident, ambulances and rescuers often require a certain amount of time to arrive at the scene. Providing immediate cardiopulmonary resuscitation (CPR) to patients might improve survival. ObjectiveThe primary objective of this study was to evaluate the feasibility of an emergency and mutual-aid app model in Taiwan and to provide a reference for government policy. MethodsA structured questionnaire was developed as a research tool. All questionnaires were designed according to the technology acceptance model, and a Likert scale was used to measure the degree of agreement or disagreement. Moreover, in-depth interviews were conducted with six experts from medical, legal, and mobile app departments. Each expert was interviewed once to discuss feasible countermeasures and suggestions. Statistical Package for the Social Sciences (SPSS version 19; IBM Corp, Armonk, New York) was used to perform all statistical analyses, including descriptive statistics, independent sample t-tests, variance analysis, and Pearson correlation analysis. ResultsWe conducted this study between October 20, 2017, and November 10, 2017, at the Taipei Medical University Hospital. Questionnaires were distributed to medical personnel, visiting guests, family members, and volunteers. A total of 113 valid questionnaires were finally obtained after the exclusion of incomplete questionnaires. Cronbach α values for self-efficacy (perceived ease of use), use attitude (perceived usefulness), and use willingness and frequency were above .85, meeting the criterion of greater than .70. We observed that the reliability of each subquestion was acceptable and the values for use attitude (perceive usefulness) and use willingness and frequency were more than .90. ConclusionsThe findings suggest that perceived ease of use and perceived usefulness of the app model affect use willingness. However, perceived usefulness had an intermediary influence on use willingness. Experts in law, medical, and technology fields consider that an emergency and mutual-aid model can be implemented in Taiwan. Along with the development of an emergency and mutual-aid app model, we recommend an increase in the number of automated external defibrillators per region and promotion of correct knowledge about CPR in order to decrease morbidity and mortality.

Published
2020
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16. Real-World Efficacy and Safety of Universal 8-Week Glecaprevir/Pibrentasvir for Treatment-Naïve Patients from a Nationwide HCV Registry in Taiwan

Author

Yang, Chun-Chi, Huang, Chung-Feng, Chang, Te-Sheng, Lo, Ching-Chu, Hung, Chao-Hung, Huang, Chien-Wei, Chong, Lee-Won, Cheng, Pin-Nan, Yeh, Ming-Lun, Peng, Cheng-Yuan, Cheng, Chien-Yu, Huang, Jee-Fu, Bair, Ming-Jong, Lin, Chih-Lang, Yang, Chi-Chieh, Wang, Szu-Jen, Hsieh, Tsai-Yuan, Lee, Tzong-Hsi, Lee, Pei-Lun, Wu, Wen-Chih, Lin, Chih-Lin, Su, Wei-Wen, Yang, Sheng-Shun, Wang, Chia-Chi, Hu, Jui-Ting, Mo, Lein-Ray, Chen, Chun-Ting, Huang, Yi-Hsiang, Chang, Chun-Chao, Huang, Chia-Sheng, Chen, Guei-Ying, Kao, Chien-Neng, Tai, Chi-Ming, Liu, Chun-Jen, Lee, Mei-Hsuan, Kuo, Hsing-Tao, Tsai, Pei-Chien, Dai, Chia-Yen, Kao, Jia-Horng, Lin, Han-Chieh, Chuang, Wang-Long, Tseng, Kuo-Chih, Chen, Chi-Yi, and Yu, Ming-Lung

Published
2024
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19. An algorithm for simplified hepatitis C virus treatment with non-specialist care based on nation-wide data from Taiwan

Author

Yu, Ming-Lung, Tai, Chi‐Ming, Mo, Lein-Ray, Kuo, Hsing-Tao, Huang, Chung-Feng, Tseng, Kuo-Chih, Lo, Ching-Chu, Bair, Ming-Jong, Wang, Szu-Jen, Huang, Jee-Fu, Yeh, Ming-Lun, Chen, Chun-Ting, Tsai, Ming-Chang, Huang, Chien-Wei, Lee, Pei-Lun, Yang, Tzeng-Hue, Huang, Yi-Hsiang, Chong, Lee-Won, Chen, Chien-Lin, Yang, Chi-Chieh, Hung, Chao-Hung, Yang, Sheng‐Shun, Cheng, Pin-Nan, Hsieh, Tsai-Yuan, Hu, Jui-Ting, Wu, Wen-Chih, Cheng, Chien-Yu, Chen, Guei-Ying, Zhou, Guo-Xiong, Tsai, Wei-Lun, Kao, Chien-Neng, Lin, Chih-Lang, Wang, Chia-Chi, Lin, Ta-Ya, Lin, Chih‐Lin, Su, Wei-Wen, Lee, Tzong-Hsi, Chang, Te-Sheng, Liu, Chun-Jen, Dai, Chia-Yen, Chen, Chi-Yi, Kao, Jia-Horng, Lin, Han-Chieh, Chuang, Wan-Long, and Peng, Cheng-Yuan

Published
2024
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22. Subsequent locoregional therapy prolongs survival in progressive hepatocellular carcinoma patients under lenvatinib treatment

Author

Po-Ting Lin, Wei Teng, Wen-Juei Jeng, Chen-Chun Lin, Chun-Yen Lin, Shi-Ming Lin, and I-Shyan Sheen

Subjects
Systemic therapy, Survival, Lenvatinib, Radiofrequency ablation, Transarterial chemoembolization, Medicine (General), R5-920
Abstract

Background: Locoregional therapy and multi-kinase inhibitor agent have been the backbone of treatment for hepatocellular carcinoma (HCC) patients. However, the effect of combination or sequential use of locoregional therapy on HCC patients receiving multi-kinase inhibitor remain uncertain. Therefore, we aim to explore whether the subsequent locoregional therapy provides better survival in HCC patients under lenvatinib treatment. Methods: From March 2018 to April 2020, a total of 78 unresectable HCC patients receiving lenvatinib were recruited. Image response was evaluated by dynamic image using the modified RECIST criteria. Among patients with tumor progression under lenvatinib treatment, whether receiving subsequent locoregional therapy or not were documented. Overall survival between two groups and the predictors for tumor progression were also analyzed. Results: Among the 78 patients receiving lenvatinib, the median age was 67.8 years old, and 69.2 % were male. Forty-four patients (56.4 %) experienced tumor progression with time to progression 5.1 months (95 % confidence interval (CI): 4.7–6.8) months. In multivariable Cox regression analysis, albumin-bilirubin (ALBI) grade II (adjusted HR: 2.883, P = 0.0104), and treatment duration less than three months (adjusted HR: 3.801, P = 0.0014) were the independent predictive factors for tumor progression, while patients achieving objective response under lenvatinib treatment within 12 weeks was the independent protective factor for tumor progression (adjusted HR: 0.144, P = 0.0020). Among the 44 patients with tumor progression, twenty-six (59.1 %) patients received subsequent locoregional therapy after tumor progression. Comparing to those with tumor progression without locoregional treatment, patients who received subsequent locoregional therapy had significantly better survival (1st year cumulative survival rate 70 % vs 27 %, log-rank P = 0.003). Conclusion: ALBI grade, treatment duration of lenvatinib, and achieving objective image response within twelve weeks were the independent predictive factors for tumor progression. Furthermore, longer overall survival was observed in tumor progression patients with subsequent locoregional therapy and with better liver preserved function.

Published
2024
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