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13. Acknowledgments

15. Contents

20. Part I: Introduction

30. Pathogenic hypothalamic extracellular matrix promotes metabolic disease

32. Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan

40. Vaccination induces broadly neutralizing antibody precursors to HIV gp41

41. Affinity gaps among B cells in germinal centers drive the selection of MPER precursors

46. Arthroscopic mini tunnel suture bridge for ACL tibial avulsion fractures repair

47. MiRNA-132/212 encapsulated by adipose tissue-derived exosomes worsen atherosclerosis progression

48. Vascular wall microenvironment: Endothelial cells original exosomes mediated melatonin-suppressed vascular calcification and vascular ageing in a m6A methylation dependent manner

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