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The authors present a very rare case observed in a 32 year old female with a huge tumor on the left side of the neck in which extensive changes characteristic for cystic lymphangioma in the lower part and for lymphangiomyomatosis in the upper part of the tumor were observed intraoperatively. On the basis of the discussed case the suggestion is put forward that these two rarely occurring diseases may have similar etiological grounds.

Protein p53 was localized ultrastructurally with 5 nm gold-streptavidin particles in cells of laryngeal carcinoma embedded in Epon 815. Postembedding technique to study p53 protein was used. Protein p53 was found predominantly in nucleus of the cells but the label was also observed in cytoplasm of the cells. Five of 15 samples from patients with laryngeal carcinoma showed positive labeling for p53, (33.3% of all examined samples). Controls of tumor cells incubation with normal mouse serum showed no labeling with gold streptavidin particles.