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1. Dietary supplementation with curcumin-loaded nanocapsules in lambs: Nanotechnology as a new tool for nutrition

Author

Hiam Marcon, Luiz G. Griss, Vitor L. Molosse, Bruno G.O. Cecere, Davi F. Alba, Karoline W. Leal, Gabriela M. Galli, Carine F. Souza, Matheus D. Baldissera, Samanta Gundel, Vitória de A. Bassotto, Aline F. Ourique, Marcelo Vedovatto, and Aleksandro S. Da Silva

Subjects
Antioxidant, Anti-inflammatory, Curcuma longa, Performance, Sheep, Animal culture, SF1-1100
Abstract

Curcumin-containing nanocapsule powder formulations have not been used in ruminant feed to date, despite the fact that curcumin is known to be a functional food additive. The objective of this study was to determine whether ethyl polymethacrylate (Eudragit L-100) nanocapsules loaded with curcumin (N-CU) would improve health and growth of lambs. Thirty-two male Lacaune lambs (body weight [BW] = 16 ± 0.99 kg; 45 d of age) were randomly assigned to 1 of 4 treatments: T0, T1, T2 and T4, representing supplementation of curcumin at 0, 1, 2, and 4 mg/kg concentrate, respectively. The animals in each treatment were allocated in 4 pens of 2 lambs each (8 lambs per treatment). The experiment lasted 17 d, with samples and measurements collected on d 0, 7, 12, and 17. The T2 lambs had greater average daily gain than T0 lambs. Regression analysis showed that the ideal dose of N-CU to enhance weight gain was 1.89 mg/kg concentrate. There were significant interactions (P

Published
2021
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2. Dietary supplementation with curcumin-loaded nanocapsules in lambs: Nanotechnology as a new tool for nutrition

Author

Luiz Gustavo Griss, Hiam Marcon, Carine F. Souza, Marcelo Vedovatto, Matheus D. Baldissera, Aline Ferreira Ourique, Bruno G.O. Cecere, Gabriela M. Galli, Karoline W. Leal, Davi F. Alba, Vitória de Almeida Bassotto, Aleksandro S. Da Silva, Samanta da Silva Gündel, and Vitor L. Molosse

Subjects
Antioxidant, Globulin, medicine.medical_treatment, Performance, medicine.disease_cause, SF1-1100, Nanocapsules, Superoxide dismutase, 03 medical and health sciences, chemistry.chemical_compound, Animal science, Food Animals, medicine, Original Research Article, Curcuma longa, 030304 developmental biology, 0303 health sciences, Sheep, Triglyceride, biology, Chemistry, 0402 animal and dairy science, 04 agricultural and veterinary sciences, 040201 dairy & animal science, Animal culture, biology.protein, Curcumin, Animal Science and Zoology, medicine.symptom, Anti-inflammatory, Weight gain, Oxidative stress
Abstract

Curcumin-containing nanocapsule powder formulations have not been used in ruminant feed to date, despite the fact that curcumin is known to be a functional food additive. The objective of this study was to determine whether ethyl polymethacrylate (Eudragit L-100) nanocapsules loaded with curcumin (N-CU) would improve health and growth of lambs. Thirty-two male Lacaune lambs (body weight [BW] = 16 ± 0.99 kg; 45 d of age) were randomly assigned to 1 of 4 treatments: T0, T1, T2 and T4, representing supplementation of curcumin at 0, 1, 2, and 4 mg/kg concentrate, respectively. The animals in each treatment were allocated in 4 pens of 2 lambs each (8 lambs per treatment). The experiment lasted 17 d, with samples and measurements collected on d 0, 7, 12, and 17. The T2 lambs had greater average daily gain than T0 lambs. Regression analysis showed that the ideal dose of N-CU to enhance weight gain was 1.89 mg/kg concentrate. There were significant interactions (P

Published
2021

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