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636 results on '"Bogoch, Isaac I"'

1. Syndrome d'autofermentation chez une femme de 50 ans

Author

Zewude, Rahel T., Croitoru, Kenneth, Das, Ronit, Goldman, Brian, and Bogoch, Isaac I.

Subjects
Microbiota (Symbiotic organisms) -- Health aspects, Bacterial infections -- Care and treatment -- Patient outcomes
Abstract

Une femme de 50 ans a ete orientee vers un service de gastroenterologie apres s'etre presentee 7 fois au service des urgences au cours des 2 annees precedentes pour des [...]

Published
2024
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2. Auto-brewery syndrome in a 50-year-old woman

Author

Zewude, Rahel T., Croitoru, Kenneth, Das, Ronit, Goldman, Brian, and Bogoch, Isaac I.

Subjects
Dysbiosis -- Case studies, Alcohol-related disorders -- Case studies, Health
Abstract

A 50-year-old woman was referred to a gastroenterology clinic after 7 presentations over the previous 2 years to emergency departments (EDs) with alcohol intoxication despite her report of no alcohol [...]

Published
2024
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3. Human movement and environmental barriers shape the emergence of dengue

Author

Harish, Vinyas, Colón-González, Felipe J., Moreira, Filipe R. R., Gibb, Rory, Kraemer, Moritz U. G., Davis, Megan, Reiner, Jr., Robert C., Pigott, David M., Perkins, T. Alex, Weiss, Daniel J., Bogoch, Isaac I., Vazquez-Prokopec, Gonzalo, Saide, Pablo Manrique, Barbosa, Gerson L., Sabino, Ester C., Khan, Kamran, Faria, Nuno R., Hay, Simon I., Correa-Morales, Fabián, Chiaravalloti-Neto, Francisco, and Brady, Oliver J.

Published
2024
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4. Clade I-Associated Mpox Cases Associated with Sexual Contact, the Democratic Republic of the Congo

Author

Kibungu, Emile M., Vakaniaki, Emmanuel H., Kinganda-Lusamaki, Eddy, Kalonji-Mukendi, Thierry, Pukuta, Elisabeth, Hoff, Nicole A., Bogoch, Isaac I., Cevik, Muge, Gonsalves, Gregg S., Hensley, Lisa E., Low, Nicola, Shaw, Souradet Y., Schillberg, Erin, Hunter, Mikayla, Lunyanga, Lygie, Linsuke, Sylvie, Madinga, Joule, Peeters, Martine, Cigolo, Jean-Claude Makangara, Ahuka-Mundeke, Steve, Muyembe, Jean- Jacques, Rimoin, Anne W., Kindrachuk, Jason, Mbala-Kingebeni, Placide, and Lushima, Robert S.

Subjects
Genomics, Infection, Disease transmission, Health
Abstract

Human mpox, caused by monkeypox virus (MPXV), is an emerging zoonotic viral disease first identified in the Democratic Republic of the Congo (DRC) (1). MPXV is endemic in multiple regions [...]

Published
2024
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8. VIH : Prophylaxie postexposition dite << de poche >>

Author

Billick, Maxime and Bogoch, Isaac I.

Subjects
Health
Abstract

1 La prophylaxie postexposition dite << de poche >> (PPP) est une strategie de prevention du VIH qui cible les personnes dont les expositions au VIH sont peu frequentes et [...]

Published
2024
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11. Dispersal patterns and influence of air travel during the global expansion of SARS-CoV-2 variants of concern

Author

Tegally, Houriiyah, Wilkinson, Eduan, Tsui, Joseph L.- H., Moir, Monika, Martin, Darren, Brito, Anderson Fernandes, Giovanetti, Marta, Khan, Kamran, Huber, Carmen, Bogoch, Isaac I., San, James Emmanuel, Poongavanan, Jenicca, Xavier, Joicymara S., Candido, Darlan da S., Romero, Filipe, Baxter, Cheryl, Pybus, Oliver G., Lessells, Richard J., Faria, Nuno R., Kraemer, Moritz U.G., and de Oliveira, Tulio

Published
2023
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12. Context-specific emergence and growth of the SARS-CoV-2 Delta variant

Author

McCrone, John T., Hill, Verity, Bajaj, Sumali, Pena, Rosario Evans, Lambert, Ben C., Inward, Rhys, Bhatt, Samir, Volz, Erik, Ruis, Christopher, Dellicour, Simon, Baele, Guy, Zarebski, Alexander E., Sadilek, Adam, Wu, Neo, Schneider, Aaron, Ji, Xiang, Raghwani, Jayna, Jackson, Ben, Colquhoun, Rachel, O’Toole, Áine, Peacock, Thomas P., Twohig, Kate, Thelwall, Simon, Dabrera, Gavin, Myers, Richard, Faria, Nuno R., Huber, Carmen, Bogoch, Isaac I., Khan, Kamran, du Plessis, Louis, Barrett, Jeffrey C., Aanensen, David M., Barclay, Wendy S., Chand, Meera, Connor, Thomas, Loman, Nicholas J., Suchard, Marc A., Pybus, Oliver G., Rambaut, Andrew, and Kraemer, Moritz U. G.

Published
2022
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13. Forme grave d'hepatite C aigue transmise sexuellement chez des hommes ayant des relations sexuelles avec d'autres homes

Author

Wei, Sunny, Bogoch, Isaac I., Dhalla, Irfan A., and Wong, David K.H.

Subjects
Hepatitis C -- Diseases -- Health aspects -- Cases, Company legal issue, Health
Abstract

Cas 1 Un homme de 33 ans, sans antecedents medicaux notables, a consulte au service des urgences en raison de malaise intense et d'ictere apparus 4 jours auparavant. Il etait [...]

Published
2023
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15. Sexually acquired severe acute hepatitis C infection in men who have sex with men

Author

Wei, Sunny, Bogoch, Isaac I., Dhalla, Irfan A., and Wong, David K.H.

Subjects
Antiviral agents -- Dosage and administration, Sexually transmitted diseases -- Prevention, MSM (Men who have sex with men) -- Health aspects -- Social aspects, Hepatitis C -- Development and progression -- Care and treatment, Health
Abstract

Case 1 A 33-year-old man with no notable medical history presented to the emergency department with 4 days of severe malaise and jaundice. He had returned to Canada from a [...]

Published
2022
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16. Incidence of typhoid and paratyphoid fever in Bangladesh, Nepal, and Pakistan: results of the Surveillance for Enteric Fever in Asia Project

Author

Garrett, Denise O, Longley, Ashley T, Aiemjoy, Kristen, Yousafzai, Mohammad T, Hemlock, Caitlin, Yu, Alexander T, Vaidya, Krista, Tamrakar, Dipesh, Saha, Shampa, Bogoch, Isaac I, Date, Kashmira, Saha, Senjuti, Islam, Mohammad Shahidul, Sayeed, K M Ishtiaque, Bern, Caryn, Shakoor, Sadia, Dehraj, Irum F, Mehmood, Junaid, Sajib, Mohammad S I, Islam, Maksuda, Thobani, Rozina S, Hotwani, Aneeta, Rahman, Najeeb, Irfan, Seema, Naga, Shiva R, Memon, Ashraf M, Pradhan, Sailesh, Iqbal, Khalid, Shrestha, Rajeev, Rahman, Hafizur, Hasan, Md Mahmudul, Qazi, Saqib H, Kazi, Abdul M, Saddal, Nasir S, Jamal, Raza, Hunzai, Mohammed J, Hossain, Tanvir, Marks, Florian, Carter, Alice S, Seidman, Jessica C, Qamar, Farah N, Saha, Samir K, Andrews, Jason R, and Luby, Stephen P

Published
2022
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17. Highly pathogenic avian influenza A (H5N1) virus

Author

Kozak, Robert, Bogoch, Isaac I., and Mubareka, Samira

Subjects
Avian influenza -- Diagnosis -- Distribution, Disease transmission -- Analysis, Company distribution practices, Health
Abstract

1 Highly pathogenic avian influenza (HPAI) H5N1 virus is spread globally by wild birds The circulating H5N1 clade (2.3.4.4b) has caused outbreaks on poultry farms and among backyard flocks, and [...]

Published
2024
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18. HIV postexposure prophylaxis-in-pocket

Author

Billick, Maxime and Bogoch, Isaac I.

Subjects
HIV infection -- Prevention, Health
Abstract

1 Postexposure prophylaxis-in-pocket (PIP) is an HIV prevention modality for people with infrequent and often unanticipated HIV exposures (e.g., 0-4 per yr) (1,2) Clinicians should identify eligible people proactively, provide [...]

Published
2024
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20. Clinical risk, sociodemographic factors, and SARS-CoV-2 infection over time in Ontario, Canada

Author

Udell, Jacob A., Behrouzi, Bahar, Sivaswamy, Atul, Chu, Anna, Ferreira-Legere, Laura E., Fang, Jiming, Goodman, Shaun G., Ezekowitz, Justin A., Bainey, Kevin R., van Diepen, Sean, Kaul, Padma, McAlister, Finlay A., Bogoch, Isaac I., Jackevicius, Cynthia A., Abdel-Qadir, Husam, Wijeysundera, Harindra C., Ko, Dennis T., Austin, Peter C., and Lee, Douglas S.

Published
2022
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25. Reported Side Effects and Adherence of Daily HIV Pre-Exposure Prophylaxis Users in Ontario, Canada: An Analysis of the Ontario Pre-Exposure Prophylaxis Cohort Study.

Author

Rudd, Monica, McGarrity, Matthew, Lisk, Ryan, MacPherson, Paul, Knox, David, Woodward, Kevin, Reinhart, Jeff, MacLeod, John, Bogoch, Isaac I., Clatworthy, Deanna, Biondi, Mia J., Sullivan, Sean, Li, Alan, Durrant, Garfield, Schonbe, Andrew, Ongoiba, Fanta, Burchell, Ann N., and Tan, Darrell H. S.

Subjects
HIV prevention, PATIENT compliance, SELF-evaluation, DIARRHEA, RESEARCH funding, QUESTIONNAIRES, HEADACHE, ABDOMINAL pain, DESCRIPTIVE statistics, PRE-exposure prophylaxis, LONGITUDINAL method, ODDS ratio, CONFIDENCE intervals, NAUSEA
Abstract

Side effects are a common concern of current and potential HIV pre-exposure prophylaxis (PrEP) users, potentially leading to missed doses. We examined the relationship between reported side effects and adherence in the Ontario PrEP Cohort Study (ON-PrEP). In total, 600 predominantly gay (87.3%), White (65.8%), and male (95.0%) participants completed questionnaires assessing the presence and severity of five side effect categories (nausea, diarrhea, headache, abdominal pain, and "other") as well as their adherence to daily PrEP (any missed doses in the previous 4 days). In total, 175 participants (29%) ever reported experiencing side effects: most commonly diarrhea (7.5% of study visits), and most were of mild severity. Lower incomes (p = 0.01), identifying as bisexual (p = 0.04), and baseline concern about side effects (p < 0.001) were associated with ever reporting side effects. The odds of reporting any side effects decreased by a factor of 0.44 (95% confidence interval 0.25–0.80) with each additional year of PrEP use, however 1 in 10 participants still reported side effects after 1 year of use. The odds of reporting optimal adherence were 0.48 (0.28–0.83) times lower for participants reporting any side effects, 0.67 (0.51–0.89) times lower per additional side effect category reported, and 0.78 (0.65–0.97) times lower per incremental increase in side effect severity ratings. We found some evidence of interaction between side effect measures and duration of PrEP use, suggesting that these relationships were stronger for participants taking PrEP for longer. Clinicians should make efforts to ascertain patients' experience of side effects and consider risk counseling and alternative PrEP regimens to promote adherence. [ABSTRACT FROM AUTHOR]

Published
2024
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32. Hepatitis E virus in the Kathmandu Valley: Insights from a representative longitudinal serosurvey.

Author

Katuwal, Nishan, Thapa, Melina, Shrestha, Sony, Vaidya, Krista, Bogoch, Isaac I., Shrestha, Rajeev, Andrews, Jason R., Tamrakar, Dipesh, and Aiemjoy, Kristen

Subjects
HEPATITIS E virus, YOUNG adults, FOOD contamination, INFECTIOUS disease transmission, WATER pollution
Abstract

Background: Hepatitis-E virus (HEV), an etiologic agent of acute inflammatory liver disease, is a significant cause of morbidity and mortality in South Asia. HEV is considered endemic in Nepal; but data on population-level infection transmission is sparse. Methods: We conducted a longitudinal serosurvey in central Nepal to assess HEV exposure. At each visit, capillary blood samples were collected and analyzed for the presence of anti-HEV IgG antibodies. The study took place between February 2019 and April 2021, with up to 4 visits per participant approximately 6 months apart. Results: We collected 2513 samples from 923 participants aged 0–25 years, finding a seroprevalence of 4.8% and a seroincidence rate of 10.9 per 1000 person-years. Young adults and individuals consuming surface water faced the highest incidence of infection. Geospatial analysis identified potential HEV clusters, suggesting a need for targeted interventions. Significance: Our findings demonstrate that HEV is endemic in Nepal and that the risk of infection increases with age. Author summary: Hepatitis-E virus (HEV) is an infectious cause of acute liver disease and is primarily transmitted through contaminated food and water. It has emerged as a leading cause of acute clinical hepatitis in South Asia. Pregnant women face the highest risk of complications and mortality. To better understand the impact of HEV in Nepal, we conducted a two-year cohort study in the Kathmandu Valley region. We collected dried blood spots from participants every 6 months and tested the samples to detect past and new infections of HEV. Our study, involving 923 individuals, revealed that 4.8% had IgG antibodies against HEV, indicating past exposure. Each year, about 11 in 1000 people between the ages of 1 and 25 years are newly exposed to the virus. The highest infection rates were among young adults and those using untreated surface water. Our study mapped the distribution of HEV, identifying specific areas with higher infection rates. [ABSTRACT FROM AUTHOR]

Published
2024
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33. HIV pre-exposure prophylaxis and opportunities for vaccination against hepatitis A virus, hepatitis B virus and human papillomavirus: an analysis of the Ontario PrEP cohort study.

Author

McGarrity, Matthew W., Lisk, Ryan, MacPherson, Paul, Knox, David, Woodward, Kevin S., Reinhart, Jeffrey, MacLeod, John, Bogoch, Isaac I., Clatworthy, Deanna, Biondi, Mia J., Sullivan, Sean T., Li, Alan T. W., Durrant, Garfield, Schonbe, Andrew, Ongoiba, Fanta, Raboud, Janet, Burchell, Ann N., and Tan, Darrell H. S.

Published
2024
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34. Hybrid immunity from severe acute respiratory syndrome coronavirus 2 infection and vaccination in Canadian adults: A cohort study.

Author

Brown, Patrick E., Sze Hang Fu, Newcombe, Leslie, Xuyang Tang, Nagelkerke, Nico, Birnboim, H. Chaim, Bansal, Aiyush, Colwill, Karen, Mailhot, GeneviÃ?ve, Delgado-Brand, Melanie, Tursun, Tulunay, Qi, Freda, Gingras, Anne-Claude, Slutsky, Arthur S., Pasic, Maria D., Companion, Jeffrey, Bogoch, Isaac I., Morawski, Ed, Lam, Teresa, and Reid, Angus

Published
2024
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37. Le depistage des personnes asymptomatiques au moyen de tests antigeniques rapides: un outil de sante publique pour lutter contre la COVID-19

Author

Schwartz, Kevin L., McGeer, Allison J., and Bogoch, Isaac I.

Subjects
Coronaviruses -- International aspects, Health
Abstract

Partout au Canada, la lutte contre la deuxieme vague de la pandemie de maladie a coronavirus 2019 (COVID-19) a ete rendue plus difficile par l'utilisation insuffisante des outils efficaces. Il [...]

Published
2021
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40. Rapid antigen screening of asymptomatic people as a public health tool to combat COVID-19

Author

Schwartz, Kevin L., McGeer, Allison J., and Bogoch, Isaac I.

Subjects
Epidemics -- Control -- Canada, Immune system -- Testing, Public health, Carrier state (Communicable diseases) -- Diagnosis, Health
Abstract

Jurisdictions across Canada have been trying to combat a second wave of the coronavirus disease 2019 (COVID-19) pandemic without using all the available tools. Accumulating evidence has shown that people [...]

Published
2021
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49. Local, national, and regional viral haemorrhagic fever pandemic potential in Africa: a multistage analysis

Author

Pigott, David M, Deshpande, Aniruddha, Letourneau, Ian, Morozoff, Chloe, Reiner, Robert C, Jr, Kraemer, Moritz U G, Brent, Shannon E, Bogoch, Isaac I, Khan, Kamran, Biehl, Molly H, Burstein, Roy, Earl, Lucas, Fullman, Nancy, Messina, Jane P, Mylne, Adrian Q N, Moyes, Catherine L, Shearer, Freya M, Bhatt, Samir, Brady, Oliver J, Gething, Peter W, Weiss, Daniel J, Tatem, Andrew J, Caley, Luke, De Groeve, Tom, Vernaccini, Luca, Golding, Nick, Horby, Peter, Kuhn, Jens H, Laney, Sandra J, Ng, Edmond, Piot, Peter, Sankoh, Osman, Murray, Christopher J L, and Hay, Simon I

Published
2017
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