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910 results on '"Bernardis, P"'

1. The MISTRAL Instrument and the Characterization of Its Detector Array

Author

Paiella, A., Cacciotti, F., Isopi, G., Barbavara, E., Battistelli, E. S., de Bernardis, P., Capalbo, V., Carbone, A., Carretti, E., Ciccalotti, E., Columbro, F., Coppolecchia, A., Cruciani, A., D’Alessandro, G., De Petris, M., Govoni, F., Lamagna, L., Levati, E., Marongiu, P., Mascia, A., Masi, S., Molinari, E., Murgia, M., Navarrini, A., Novelli, A., Occhiuzzi, A., Orlati, A., Pappalardo, E., Pettinari, G., Piacentini, F., Pisanu, T., Poppi, S., Porceddu, I., Ritacco, A., Schirru, M. R., and Vargiu, G.

Published
2024
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9. Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory

Author

Michelatti, Daniela, Beyes, Sven, Bernardis, Chiara, Negri, Maria Luce, Morelli, Leonardo, Bediaga, Naiara Garcia, Poli, Vittoria, Fagnocchi, Luca, Lago, Sara, D’Annunzio, Sarah, Cona, Nicole, Gaspardo, Ilaria, Bianchi, Aurora, Jovetic, Jovana, Gianesello, Matteo, Turdo, Alice, D’Accardo, Caterina, Gaggianesi, Miriam, Dori, Martina, Forcato, Mattia, Crispatzu, Giuliano, Rada-Iglesias, Alvaro, Sosa, Maria Soledad, Timmers, H. T. Marc, Bicciato, Silvio, Todaro, Matilde, Tiberi, Luca, and Zippo, Alessio

Published
2024
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15. Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory

Author

Daniela Michelatti, Sven Beyes, Chiara Bernardis, Maria Luce Negri, Leonardo Morelli, Naiara Garcia Bediaga, Vittoria Poli, Luca Fagnocchi, Sara Lago, Sarah D’Annunzio, Nicole Cona, Ilaria Gaspardo, Aurora Bianchi, Jovana Jovetic, Matteo Gianesello, Alice Turdo, Caterina D’Accardo, Miriam Gaggianesi, Martina Dori, Mattia Forcato, Giuliano Crispatzu, Alvaro Rada-Iglesias, Maria Soledad Sosa, H. T. Marc Timmers, Silvio Bicciato, Matilde Todaro, Luca Tiberi, and Alessio Zippo

Subjects
Science
Abstract

Abstract Metastasis arises from disseminated tumour cells (DTCs) that are characterized by intrinsic phenotypic plasticity and the capability of seeding to secondary organs. DTCs can remain latent for years before giving rise to symptomatic overt metastasis. In this context, DTCs fluctuate between a quiescent and proliferative state in response to systemic and microenvironmental signals including immune-mediated surveillance. Despite its relevance, how intrinsic mechanisms sustain DTCs plasticity has not been addressed. By interrogating the epigenetic state of metastatic cells, we find that tumour progression is coupled with the activation of oncogenic enhancers that are organized in variable interconnected chromatin domains. This spatial chromatin context leads to the activation of a robust transcriptional response upon repeated exposure to retinoic acid (RA). We show that this adaptive mechanism sustains the quiescence of DTCs through the activation of the master regulator SOX9. Finally, we determine that RA-stimulated transcriptional memory increases the fitness of metastatic cells by supporting the escape of quiescent DTCs from NK-mediated immune surveillance. Overall, these findings highlight the contribution of oncogenic enhancers in establishing transcriptional memories as an adaptive mechanism to reinforce cancer dormancy and immune escape, thus amenable for therapeutic intervention.

Published
2024
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17. Measurements of dichroic bow-tie antenna arrays with integrated cold-electron bolometers using YBCO oscillators

Author

Leonid S. Revin, Dmitry A. Pimanov, Alexander V. Chiginev, Anton V. Blagodatkin, Viktor O. Zbrozhek, Andrey V. Samartsev, Anastasia N. Orlova, Dmitry V. Masterov, Alexey E. Parafin, Victoria Yu. Safonova, Anna V. Gordeeva, Andrey L. Pankratov, Leonid S. Kuzmin, Anatolie S. Sidorenko, Silvia Masi, and Paolo de Bernardis

Subjects
cosmic microwave background, b mode, cold-electron bolometer, dichroic antenna array, dipole bow-tie antenna, josephson junction, lspe, Technology, Chemical technology, TP1-1185, Science, Physics, QC1-999
Abstract

We consider properties of dichroic antenna arrays on a silicon substrate with integrated cold-electron bolometers to detect radiation at frequencies of 210 and 240 GHz. This frequency range is widely used in cosmic microwave background experiments in space, balloon, and ground-based missions such as BICEP Array, LSPE, LiteBIRD, QUBIC, Simons Observatory, and AliCPT. As a direct radiation detector, we use cold-electron bolometers, which have high sensitivity and a wide operating frequency range, as well as immunity to spurious cosmic rays. Their other advantages are the compact size of the order of a few micrometers and the effect of direct electron cooling, which can improve sensitivity in typical closed-loop cycle 3He cryostats for space applications. We study a novel concept of cold-electron bolometers with two SIN tunnel junctions and one SN contact. The amplitude–frequency characteristics measured with YBCO Josephson Junction oscillators show narrow peaks at 205 GHz for the 210 GHz array and at 225 GHz for the 240 GHz array; the separation of these two frequency bands is clearly visible. The noise equivalent power level at an operating point in the current bias mode is 5 × 10−16 W/√Hz.

Published
2024
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18. A 350 GHz array of LEKIDs for balloon-borne CMB observations

Author

Cacciotti, F., Paiella, A., Avestruz, C., Tackur, R. Basu, Battistelli, E.S., de Bernardis, P., Bulbul, E., Columbro, F., Coppolecchia, A., Cray, S., D’Alessandro, G., De Petris, M., Hanany, S., Lamagna, L., Lau, E., Masi, S., Pettinari, G., Piacentini, F., Sayers, J., Zhuravleva, I., and Zuhone, J.

Published
2024
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21. Performance of the polarization leakage correction in the PILOT data

Author

Bernard, Jean-Philippe, Bernard, Adam, Roussel, Hélène, Choubani, Ilyes, Alina, Dana, Aumont, Jonathan, Hughes, Annie, Ristorcelli, Isabelle, Stever, Samantha, Matsumura, Tomotake, Sugiyama, Shinya, Komatsu, Kunimoto, de Gasperis, Giancarlo, Ferrière, Katia, Guillet, Vincent, Ysard, Nathalie, Ade, Peter, de Bernardis, Paolo, Bray, Nicolas, Crane, Bruno, Dubois, Jean-Pierre, Griffin, Matt, Hargrave, Peter, Longval, Yuying, Louvel, Stephane, Maffei, Bruno, Masi, Silvia, Mot, Baptiste, Montel, Johan, Pajot, François, Pérot, Etienne, Ponthieu, Nicolas, Rodriguez, Louis, Sauvage, Valentin, Savini, Giorgio, Tucker, Carole, and Vacher, François

Published
2023
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22. Science and Innovation with Stratospheric Balloons: The Olimpo & Lspe/Swipe Projects

Author

Volpe, A., Albano, M., Ade, P. A. R., Baldini, A. M., Baù, A., Battistelli, E., de Bernardis, P., Biasotti, M., Boscaleri, A., Cei, F., Colantoni, I., Columbro, F., Coppi, G., Coppolecchia, A., D’Alessandro, G., De Petris, M., Fafone, V., Fontanelli, F., Gervasi, M., Galli, L., Gatti, F., Grosso, D., Lamagna, L., Magneville, C., Masi, S., Mauskopf, P., May, A., Mele, L., Paiella, A., Pettinari, G., Passerini, A., Piacentini, F., Piccirillo, L., Pisano, G., Polenta, G., Presta, G., Schillaci, A., Signorelli, G., Siri, B., Spinella, F., Tartari, A., Tommasi, E., Tucker, C., Vaccaro, D., Vdovin, V. F., Zannoni, M., and Yvon, D.

Published
2023
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26. Pulse Tube Cooler with > 100 m Flexible Lines for Operation of Cryogenic Detector Arrays at Large Radiotelescopes

Author

Coppolecchia, A., Battistelli, E. S., Masi, S., Marongiu, P., Barbavara, E., de Bernardis, P., Cacciotti, F., Carretti, E., Columbro, F., Cruciani, A., D’Alessandro, G., De Petris, M., Govoni, F., Isopi, G., Lamagna, L., Mele, L., Molinari, E., Murgia, M., Navarrini, A., Orlati, A., Paiella, A., Pettinari, G., Piacentini, F., Pisanu, T., Poppi, S., Presta, G., and Radiconi, F.

Published
2023
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27. Sensitivity Modeling for LiteBIRD

Author

Hasebe, T., Ade, P. A. R., Adler, A., Allys, E., Alonso, D., Arnold, K., Auguste, D., Aumont, J., Aurlien, R., Austermann, J., Azzoni, S., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Bartolo, N., Basak, S., Battistelli, E., Bautista, L., Beall, J., Beck, D., Beckman, S., Benabed, K., Bermejo-Ballesteros, J., Bersanelli, M., Bonis, J., Borrill, J., Bouchet, F., Boulanger, F., Bounissou, S., Brilenkov, M., Brown, M. L., Bucher, M., Calabrese, E., Calvo, M., Campeti, P., Carones, A., Casas, F. J., Catalano, A., Challinor, A., Chan, V., Cheung, K., Chinone, Y., Cliche, J., Columbro, F., Coulton, W., Cubas, J., Cukierman, A., Curtis, D., D’Alessandro, G., Dachlythra, K., de Bernardis, P., de Haan, T., de la Hoz, E., De Petris, M., Torre, S. Della, Dickinson, C., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Douillet, D., Duband, L., Ducout, A., Duff, S., Duval, J. M., Ebisawa, K., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Galli, S., Galloway, M., Ganga, K., Gao, J. R., Genova-Santos, R. T., Gerbino, M., Gervasi, M., Ghigna, T., Giardiello, S., Gjerløw, E., Gradziel, M. L., Grain, J., Grandsire, L., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hamilton, J., Hargrave, P., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versillé, S., Hergt, L. T., Herman, D., Herranz, D., Hill, C. A., Hilton, G., Hivon, E., Hlozek, R. A., Hoang, T. D., Hornsby, A. L., Hoshino, Y., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G., Jones, M., Kaga, T., Kashima, S., Katayama, N., Kato, A., Kawasaki, T., Keskitalo, R., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kreykenbohm, I., Kuo, C. L., Kushino, A., Lamagna, L., Lanen, J. V., Laquaniello, G., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Louis, T., Luzzi, G., Macias-Perez, J., Maciaszek, T., Maffei, B., Maino, D., Maki, M., Mandelli, S., Maris, M., Martínez-González, E., Masi, S., Massa, M., Matarrese, S., Matsuda, F. T., Matsumura, T., Mele, L., Mennella, A., Migliaccio, M., Minami, Y., Mitsuda, K., Moggi, A., Monfardini, A., Montgomery, J., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagano, Y., Nagasaki, T., Nagata, R., Nakamura, S., Nakano, R., Namikawa, T., Nati, F., Natoli, P., Nerval, S., Nishibori, T., Nishino, H., Noviello, F., O’Sullivan, C., Odagiri, K., Ogawa, H., Ogawa, H., Oguri, S., Ohsaki, H., Ohta, I. S., Okada, N., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Passerini, A., Patanchon, G., Pelgrim, V., Peloton, J., Piacentini, F., Piat, M., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Remazeilles, M., Ritacco, A., Roudil, G., Rubino-Martin, J., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Sasaki, M., Savini, G., Scott, D., Seibert, J., Sekimoto, Y., Sherwin, B., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Smecher, G., Spinella, F., Stever, S., Stompor, R., Sugiyama, S., Sullivan, R., Suzuki, A., Suzuki, J., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takase, Y., Takeda, Y., Tartari, A., Tavagnacco, D., Taylor, A., Taylor, E., Terao, Y., Thermeau, J., Thommesen, H., Thompson, K. L., Thorne, B., Toda, T., Tomasi, M., Tominaga, M., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ullom, J., Vacher, L., Vermeulen, G., Vielva, P., Villa, F., Vissers, M., Vittorio, N., Wandelt, B., Wang, W., Watanuki, K., Wehus, I. K., Weller, J., Westbrook, B., Wilms, J., Winter, B., Wollack, E. J., Yamasaki, N. Y., Yoshida, T., Yumoto, J., Zacchei, A., Zannoni, M., and Zonca, A.

Published
2022
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28. Measuring CMB Spectral Distortions from Antarctica with COSMO: Blackbody Calibrator Design and Performance Forecast

Author

Mele, L., Battistelli, E. S., de Bernardis, P., Bersanelli, M., Columbro, F., Coppi, G., Coppolecchia, A., D’Alessandro, G., De Petris, M., Franceschet, C., Gervasi, M., Lamagna, L., Limonta, A., Manzan, E., Marchitelli, E., Masi, S., Mennella, A., Nati, F., Paiella, A., Pettinari, G., Piacentini, F., Piccirillo, L., Pisano, G., Realini, S., Tucker, C., and Zannoni, M.

Published
2022
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29. MISTRAL and its KIDs

Author

Paiella, A., de Bernardis, P., Cacciotti, F., Coppolecchia, A., Masi, S., Barbavara, E., Battistelli, E. S., Carretti, E., Columbro, F., Cruciani, A., D’Alessandro, G., De Petris, M., Govoni, F., Isopi, G., Lamagna, L., Marongiu, P., Mele, L., Molinari, E., Murgia, M., Navarrini, A., Orlati, A., Pettinari, G., Piacentini, F., Pisanu, T., Poppi, S., Presta, G., and Radiconi, F.

Published
2022
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31. QUBIC Experiment Toward the First Light

Author

D’Alessandro, G., Battistelli, E. S., de Bernardis, P., De Petris, M., Gamboa Lerena, M. M., Grandsire, L., Hamilton, J.-Ch., Marnieros, S., Masi, S., Mennella, A., Mousset, L., O’Sullivan, C., Piat, M., Tartari, A., Torchinsky, S. A., Voisin, F., Zannoni, M., Ade, P., Alberro, J. G., Almela, A., Amico, G., Arnaldi, L. H., Auguste, D., Aumont, J., Azzoni, S., Banfi, S., Baù, A., Bélier, B., Bennett, D., Bergé, L., Bernard, J.-Ph., Bersanelli, M., Bigot-Sazy, M.-A., Bonaparte, J., Bonis, J., Bunn, E., Burke, D., Buzi, D., Cavaliere, F., Chanial, P., Chapron, C., Charlassier, R., Cobos Cerutti, A. C., Columbro, F., Coppolecchia, A., De Gasperis, G., De Leo, M., Dheilly, S., Duca, C., Dumoulin, L., Etchegoyen, A., Fasciszewski, A., Ferreyro, L. P., Fracchia, D., Franceschet, C., Ganga, K. M., García, B., García Redondo, M. E., Gaspard, M., Gayer, D., Gervasi, M., Giard, M., Gilles, V., Giraud-Heraud, Y., Gómez Berisso, M., González, M., Gradziel, M., Hampel, M. R., Harari, D., Henrot-Versillé, S., Incardona, F., Jules, E., Kaplan, J., Kristukat, C., Lamagna, L., Loucatos, S., Louis, T., Maffei, B., Marty, W., Mattei, A., May, A., McCulloch, M., Mele, L., Melo, D., Montier, L., Mundo, L. M., Murphy, J. A., Murphy, J. D., Nati, F., Olivieri, E., Oriol, C., Paiella, A., Pajot, F., Passerini, A., Pastoriza, H., Pelosi, A., Perbost, C., Perciballi, M., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Platino, M., Polenta, G., Prêle, D., Presta, G., Puddu, R., Rambaud, D., Rasztocky, E., Ringegni, P., Romero, G. E., Salum, J. M., Schillaci, A., Scóccola, C. G., Scully, S., Spinelli, S., Stankowiak, G., Stolpovskiy, M., Supanitsky, A. D., Thermeau, J.-P., Timbie, P., Tomasi, M., Tucker, G., Tucker, C., Viganò, D., Vittorio, N., Wicek, F., Wright, M., and Zullo, A.

Published
2022
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36. Optical Characterization of OMT-Coupled TES Bolometers for LiteBIRD

Author

Hubmayr, J., Ade, P. A. R., Adler, A., Allys, E., Alonso, D., Arnold, K., Auguste, D., Aumont, J., Aurlien, R., Austermann, J. E., Azzoni, S., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Bartolo, N., Basak, S., Battistelli, E., Bautista, L., Beall, J. A., Beck, D., Beckman, S., Benabed, K., Bermejo-Ballesteros, J., Bersanelli, M., Bonis, J., Borrill, J., Bouchet, F., Boulanger, F., Bounissou, S., Brilenkov, M., Brown, M. L., Bucher, M., Calabrese, E., Calvo, M., Campeti, P., Carones, A., Casas, F. J., Catalano, A., Challinor, A., Chan, V., Cheung, K., Chinone, Y., Chiocchetta, C., Clark, S. E., Clermont, L., Clesse, S., Cliche, J., Columbro, F., Connors, J. A., Coppolecchia, A., Coulton, W., Cubas, J., Cukierman, A., Curtis, D., Cuttaia, F., D’Alessandro, G., Dachlythra, K., de Bernardis, P., de Haan, T., de la Hoz, E., De Petris, M., Della Torre, S., Daz Garca, J. J., Dickinson, C., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Douillet, D., Doumayrou, E., Duband, L., Ducout, A., Duff, S. M., Duval, J. M., Ebisawa, K., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Farrens, S., Finelli, F., Flauger, R., Fleury-Frenette, K., Franceschet, C., Fuskeland, U., Galli, L., Galli, S., Galloway, M., Ganga, K., Gao, J. R., Genova-Santos, R. T., Georges, M., Gerbino, M., Gervasi, M., Ghigna, T., Giardiello, S., Gjerlw, E., Gonzles, R. Gonzlez, Gradziel, M. L., Grain, J., Grandsire, L., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hamilton, J., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versill, S., Hensley, B., Herman, D., Herranz, D., Hilton, G. C., Hivon, E., Hlozek, R. A., Hoang, D., Hornsby, A. L., Hoshino, Y., Ichiki, K., Iida, T., Ikemoto, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G., Jones, M., Kaga, T., Kashima, S., Katayama, N., Kato, A., Kawasaki, T., Keskitalo, R., Kintziger, C., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kreykenbohm, I., Kuo, C. L., Kushino, A., Lamagna, L., Lanen, J. V., Laquaniello, G., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Link, M. J., Lonappan, A. I., Louis, T., Luzzi, G., Macias-Perez, J., Maciaszek, T., Maffei, B., Maino, D., Maki, M., Mandelli, S., Maris, M., Marquet, B., Martnez-Gonzlez, E., Martire, F. A., Masi, S., Massa, M., Masuzawa, M., Matarrese, S., Matsuda, F. T., Matsumura, T., Mele, L., Mennella, A., Migliaccio, M., Minami, Y., Mitsuda, K., Moggi, A., Monelli, M., Monfardini, A., Montgomery, J., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagano, Y., Nagasaki, T., Nagata, R., Nakamura, S., Nakano, R., Namikawa, T., Nati, F., Natoli, P., Nerval, S., Neto Godry Farias, N., Nishibori, T., Nishino, H., Noviello, F., O’Neil, G. C., O’Sullivan, C., Odagiri, K., Ochi, H., Ogawa, H., Ogawa, H., Oguri, S., Ohsaki, H., Ohta, I. S., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Pascual Cisneros, G., Passerini, A., Patanchon, G., Pelgrim, V., Peloton, J., Pettorino, V., Piacentini, F., Piat, M., Piccirilli, G., Pinsard, F., Pisano, G., Plesseria, J., Polenta, G., Poletti, D., Prouv, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Reintsema, C. D., Remazeilles, M., Ritacco, A., Rosier, P., Roudil, G., Rubino-Martin, J., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Sasaki, M., Savini, G., Scott, D., Seibert, J., Sekimoto, Y., Sherwin, B., Shinozaki, K., Shiraishi, M., Shirron, P., Shitvov, A., Signorelli, G., Smecher, G., Spinella, F., Starck, J., Stever, S., Stompor, R., Sudiwala, R., Sugiyama, S., Sullivan, R., Suzuki, A., Suzuki, J., Suzuki, T., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takase, Y., Takeda, Y., Tartari, A., Tavagnacco, D., Taylor, A., Taylor, E., Terao, Y., Terenzi, L., Thermeau, J., Thommesen, H., Thompson, K. L., Thorne, B., Toda, T., Tomasi, M., Tominaga, M., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ueki, R., Ullom, J. N., Umemori, K., Vacher, L., Van Lanen, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M. R., Vittorio, N., Wandelt, B., Wang, W., Wehus, I. K., Weller, J., Westbrook, B., Weymann-Despres, G., Wilms, J., Winter, B., Wollack, E. J., Yamasaki, N. Y., Yoshida, T., Yumoto, J., Watanuki, K., Zacchei, A., Zannoni, M., and Zonca, A.

Published
2022
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39. Hand surgery and hand therapy clinical practice guideline for epidermolysis bullosa

Author

Rachel Box, Catina Bernardis, Alexander Pleshkov, Nicky Jessop, Catherine Miller, Jennifer Skye, Virginia O’Brien, Matthew Veerkamp, Anna Carolina Ferreira da Rocha, and Roger Cornwall

Subjects
Medicine
Abstract

Abstract What is already known about this topic? Epidermolysis bullosa (EB) causes blistering and scarring of the hands resulting in contractures fused web spaces and altered function. Surgery is needed to release contractures and web spaces and hand therapy is essential to maintain results, approaches for both differ. What does this study add? These guidelines aim to provide information on the surgical and conservative therapeutic hand management of children and adults diagnosed with EB. They are based on available evidence and expert consensus to assist hand surgeons and therapists in decision making, planning and treatment. They highlight the importance of a holistic multidisciplinary team (MDT) approach, where patient priorities are paramount.

Published
2022
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40. Nonlinearity-induced symmetry breaking in a system of two parametrically driven Kerr-Duffing oscillators

Author

F Hellbach, D De Bernardis, M Saur, I Carusotto, W Belzig, and G Rastelli

Subjects
parametric interaction, Kerr resonators, Duffing resonators, nonlinear dynamics, Science, Physics, QC1-999
Abstract

We study the classical dynamics of a system comprising a pair of Kerr-Duffing nonlinear oscillators, which are coupled through a nonlinear interaction and subjected to a parametric drive. Using the rotating wave approximation, we analyze the steady-state solutions for the amplitudes of the two oscillators. For the case of almost identical oscillators, we investigate separately the cases in which only one oscillator is parametrically driven and in which both oscillators are simultaneously driven. In the latter regime, we demonstrate that even when the parametric drives acting on the two oscillators are identical, the system can transition from a stable symmetric solution to a broken-symmetry solution as the detuning is varied.

Published
2024
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41. Measuring the CMB primordial B-modes with Bolometric Interferometry

Author

Mennella A., Ade P., Almela A., Amico G., Arnaldi L.H., Aumont J., Banfi S., Battistelli E.S., Bélier B., Bergé L., Bernard J.-Ph., Bersanelli M., Bonaparte J., Bonilla J.D., Bunn E., Buzi D., Cacciotti F., Camilieri D., Cavaliere F., Chanial P., Chapron C., Colombo L., Columbro F., Coppolecchia A., Costanza M.B., D’Alessandro G., de Bernardis P., De Gasperis G., De Leo M., De Petris M., Del Castillo N., Dheilly S., Etchegoyen A., Ferazzoli S., Ferreyro L.P., Franceschet C., Lerena M.M. Gamboa, Ganga K., García B., Redondo M.E. García, Gayer D., Geria J.M., Gervasi M., Giard M., Gilles V., Berisso M. Gómez, Gonzalez M., Gradziel M., Grandsire L., Hamilton J.-Ch., Hampel M.R., Isopi G., Kaplan J., Lamagna L., Lazarte F., Loucatos S., Maffei B., Mancilla A., Mandelli S., Manzan E., Marchitelli E., Marnieros S., Marty W., Masi S., May A., Maya J., McCulloch M., Mele L., Melo D., Mirón-Granese N., Montier L., Mousset L., Müller N., Nati F., O’Sullivan C., Paiella A., Pajot F., Paradiso S., Pascale E., Passerini A., Pelosi A., Perciballi M., Pezzotta F., Piacentini F., Piat M., Piccirillo L., Pisano G., Platino M., Polenta G., Prêle D., Rambaud D., Ramos G., Rasztocky E., Régnier M., Reyes C., Rodríguez F., Rodríguez C.A., Romero G.E., Salum J.M., Schillaci A., Scóccola C., Stankowiak G., Tartari A., Thermeau J.-P., Timbie P., Tomasi M., Torchinsky S., Tucker G., Tucker C., Vacher L., Voisin F., Wright M., Zannoni M., and Zullo A.

Subjects
Physics, QC1-999
Abstract

The Q&U Bolometric Interferometer for Cosmology (QL’BIC) is the first bolometric interferometer designed to measure the primordial B-mode polarization of the Cosmic Microwave Background (CMB). Bolometric interferometry is a novel technique that combines the sensitivity of bolometric detectors with the control of systematic effects that is typical of interferometry, both key features in the quest for the faint signal of the primordial B-modes. A unique feature is the so-called “spectral imaging”, i.e., the ability to recover the sky signal in several sub-bands within the physical band during data analysis. This feature provides an in-band spectral resolution of ∆v/v ~ 0.04 that is unattainable by a traditional imager. This is a key tool for controlling the Galactic foregrounds contamination. In this paper, we describe the principles of bolometric interferometry, the current status of the QU BIC experiment and future prospects.

Published
2024
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42. The advantage of Bolometric Interferometry for controlling Galactic foreground contamination in CMB primordial B-modes measurements

Author

Manzan E., Regnier M., Hamilton J-Ch., Mennella A., Errard J., Zapelli L., Torchinsky S.A., Paradiso S., Battistelli E., Bersanelli M., De Bernardis P., De Petris M., D’Alessandro G., Gervasi M., Masi S., Piat M., Rasztocky E., Romero G.E, Scoccola C.G., and Zannoni M.

Subjects
Physics, QC1-999
Abstract

In the quest for the faint primordial B-mode polarization of the Cosmic Microwave Background, three are the key requirements for any present or future experiment: an utmost sensitivity, excellent control over instrumental systematic effects and over Galactic foreground contamination. Bolometric Interferometry (BI) is a novel technique that matches them all by combining the sensitivity of bolometric detectors, the control of instrumental systematics from interferometry and a software-based, tunable, in-band spectral resolution due to its ability to perform band-splitting during data analysis (spectral imaging). In this paper, we investigate how the spectral imaging capability of BI can help in detecting residual contamination in case an over-simplified model of foreground emission is assumed in the analysis. To mimic this situation, we focus on the next generation of ground-based CMB experiment, CMB-S4, and compare its anticipated sensitivities, frequency and sky coverage with a hypothetical version of the same experiment based on BI, CMB-S4/BI, assuming that lineof-sight (LOS) frequency decorrelation is present in dust emission but is not accounted for during component separation. We show results from a Monte-Carlo analysis based on a parametric component separation method (FGBuster), highlighting how BI has the potential to diagnose the presence of foreground residuals in estimates of the tensor-to-scalar ratio r in the case of unaccounted Galactic dust LOS frequency decorrelation.

Published
2024
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43. Observing galaxy clusters and the cosmic web through the Sunyaev Zel’dovich effect with MISTRAL

Author

Battistelli E.S., Barbavara E., de Bernardis P., Cacciotti F., Capalbo V., Carbone A., Carretti E., Ciccalotti D., Columbro F., Coppolecchia A., Cruciani A., D’Alessandro G., De Petris M., Govoni F., Isopi G., Lamagna L., Levati E., Marongiu P., Mascia A., Masi S., Molinari E., Murgia M., Navarrini A., Novelli A., Occhiuzzi A., Orlati A., Pappalardo E., Paiella A., Pettinari G., Piacentini F., Pisanu T., Poppi S., Porceddu I., Ritacco A., Schirru M.R., and Vargiu G.P.

Subjects
Physics, QC1-999
Abstract

Galaxy clusters and surrounding medium, can be studied using X-ray bremsstrahlung emission and Sunyaev Zel’dovich (SZ) effect. Both astrophysical probes, sample the same environment with different parameters dependance. The SZ effect is relatively more sensitive in low density environments and thus is useful to study the filamentary structures of the cosmic web. In addition, observations of the matter distribution require high angular resolution in order to be able to map the matter distribution within and around galaxy clusters. MISTRAL is a camera working at 90GHz which, once coupled to the Sardinia Radio Telescope (SRT), can reach 12″ angular resolution over 4′ field of view (f.o.v.). The forecasted sensitivity drives to a Noise Equivalent Flux Density of ≃ 10–15 mJy √s and the mapping speed is MS = 380′2 mJy−2 h−1. MISTRAL was recently installed at the focus of the SRT and soon will take its first photons.

Published
2024
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44. OLIMPO: A balloon-borne SZE imager to probe ICM dynamics and the WHIM

Author

Sayers J., Avestruz C., Thakur R. Basu, Battistelli E., Bulbul E., Cacciotti F., Columbro F., Coppolecchia A., Cray S., D’Alessandro G., de Bernardis P., De Petris M., Hanany S., Lamagna L., Lau E., Masi S., Paiella A., Pettinari G., Piacentini F., Rapaport E., Rudnick L., Zhuravleva I., and ZuHone J.

Subjects
Physics, QC1-999
Abstract

OLIMPO is a proposed Antarctic balloon-borne Sunyaev-Zel’dovich effect (SZE) imager to study gas dynamics associated with structure formation along with the properties of the warm-hot intergalactic medium (WHIM) residing in the connective filaments. During a 25 day flight OLIMPO will image a total of 10 z∼0.05 galaxy clusters and 8 bridges at 145, 250, 365, and 460 GHz at an angular resolution of 1.0′–3.3′. The maps will be significantly deeper than those planned from CMB-S4 and CCAT-P, and will have excellent fidelity to the large angular scales of our low-z targets, which are difficult to probe from the ground. In combination with X-ray data from eROSITA and XRISM we will transform our current static view of galaxy clusters into a full dynamic picture by measuring the internal intra-cluster medium (ICM) velocity structure with the kinematic SZE, X-ray spectroscopy, and the power spectrum of ICM fluctuations. Radio observations from ASKAP and MeerKAT will be used to better understand the connection between ICM turbulence and shocks with the relativistic plasma. Beyond the cluster boundary, we will combine thermal SZE maps from OLIMPO with X-ray imaging from eROSITA to measure the thermodynamics of the WHIM residing in filaments, providing a better understanding of its properties and its contribution to the total baryon budget.

Published
2024
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48. LYMPH-Q translation, cultural adaptation and validation in Italian language: A prospective PROMs-based study on breast cancer-related arm lymphedema for patients' education.

Author

Cogliandro, Annalisa, Mirra, Carlo, Gratteri, Marco, Mannella, Viviana, Salzillo, Rosa, Bressi, Federica, Miccinilli, Sandra, De Bernardis, Riccardo, Savani, Luca, Marangi, Giovanni Francesco, and Persichetti, Paolo

Abstract

Upper Extremity Lymphedema following oncological breast surgery affects not only the patient's physique, but also the patient's psychological sphere. One of the best known PROMs-based questionnaires for investigating the condition is the LYMPH-Q. The study aimed to perform the Italian translation and cultural adaptation of the LYMPH-Q and to assess if, independently from disease evolution, arm sleeve improves QoL in these patients. Translation included 4 steps: Forward translation, Back translation, Back translation review and Patient interviews. The questionnaire was administered to 50 female patients older than 18 years of age with UEL who received a prescription for daily use of a compression sheath. A second administration took place 30 days after. Forty-four patients completed the study (Group 1: 26 patients with indication to use compression sleeve who wore it; Group 2:18 patients who despite the prescription did not want to wear it. A descriptive statistical analysis was performed with Prism 9 software. T-tests showed statistical significance for changes in "Symptoms," "Function," "Appearance" and "Psychological" scales. There were no statistically significant changes for "Information scale" in Group 1 and for all scales in Group 2. Data from this observational study show that HR-QOL analyzed from the patients' perspective also tends to improve in terms of symptoms, function, appearance, and psychological sphere in patients with BCRL when using a compression sheath. The Lymph-Q has proven to be a valuable ally of the physician attempting to improve treatment approaches for BCRL based not only on scientific evidence but also on PROMs. [ABSTRACT FROM AUTHOR]

Published
2024
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49. Inter-Letter Spacing, Inter-Word Spacing, and Font with Dyslexia-Friendly Features: Testing Text Readability in People with and without Dyslexia

Author

Galliussi, Jessica, Perondi, Luciano, Chia, Giuseppe, Gerbino, Walter, and Bernardis, Paolo

Abstract

Over the last years, several studies have suggested a possible link between dyslexia and deficits in low-level visual processing (e.g., excessive crowding). At the same time, specially designed "dyslexia-friendly" fonts appeared on the market. This class of fonts presents two main features: the particular graphic characteristics of the letterform designed to avoid confusion between similarly shaped letters, and wider inter-letter and inter-word spacing to limit crowding. The literature testing the efficacy of "dyslexia-friendly" fonts in improving reading accuracy and increasing reading speed is controversial. We evaluated the impact of letterform (with vs. without dyslexia-friendly graphic features), inter-letter spacing (standard vs. increased), and inter-word spacing (standard vs. increased) on reading accuracy and speed. Two groups of 64 children each, with and without dyslexia, read aloud 8 equivalent texts. The data collected failed to show any effect from the letterform. As regards spacing, the data showed that reading speed is impaired by an increase in inter-letter spacing not combined with an adequate increase in inter-word spacing.

Published
2020
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50. From Data Analysis to Intent-Based Recommendation: An Industrial Case Study in the Video Domain

Author

Cesare Bernardis, Maurizio Ferrari Dacrema, Fernando Benjamin Perez Maurera, Massimo Quadrana, Mario Scriminaci, and Paolo Cremonesi

Subjects
Industrial data, intent-based, session-based, user behavior, Electrical engineering. Electronics. Nuclear engineering, TK1-9971
Abstract

This work presents a comprehensive study, from an industrial perspective, of the process between the collection of raw data, and the generation of next-item recommendation, in the domain of Video-on-Demand (VoD). Most research papers focus their efforts on analyzing recommender systems on already-processed datasets, but they do not face the same challenges that occur naturally in industry, e.g., processing raw interactions logs to create datasets for testing. This paper describes the whole process between data collection and recommendation, including cleaning, processing, feature engineering, session inferring, and all the challenges that a dataset provided by an industrial player in the domain posed. Then, a comparison on the new dataset of several intent-based recommendation techniques in the next-item recommendation task follows, studying the impact of different factors like the session length, and the number of previous sessions available for a user. The results show that taking advantage of the sequential data available in the dataset benefits recommendation quality, since deep learning algorithms for session-aware recommendation are consistently the most accurate recommenders. Lastly, a summary of the different challenges in the VoD domain is proposed, discussing on the best algorithmic solutions found, and proposing future research directions to be conducted based on the results obtained.

Published
2022
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