165 results on '"Baukrowitz, Thomas"'
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2. Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels
3. Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation
4. Gain-of-function mutations in KCNK3 cause a developmental disorder with sleep apnea
5. An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier
6. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.
7. Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ channel
8. Functional Conversion between A-Type and Delayed Rectifier K + Channels by Membrane Lipids
9. Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel
10. PIP$_2$ and PIP as Determinants for ATP Inhibition of K$_{ATP}$ Channels
11. Two Functionally Distinct Subsites for the Binding of Internal Blockers to the Pore of Voltage-Activated K + Channels
12. Use-Dependent Blockers and Exit Rate of the Last Ion from the Multi-Ion Pore of a K$^+$ Channel
13. A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K+ Channels
14. Sodium permeable and “hypersensitive” TREK‐1 channels cause ventricular tachycardia
15. State-Dependent Network Connectivity Determines Gating in a K+ Channel
16. KCNJ10 gene mutations causing EAST syndrome (epilepsy, ataxia, sensorineural deafness, and tubulopathy) disrupt channel function
17. A Specific Two-pore Domain Potassium Channel Blocker Defines the Structure of the TASK-1 Open Pore
18. Validation of TREK1 ion channel activators as an immunomodulatory and neuroprotective strategy in neuroinflammation.
19. From head to tail—atomistic mechanism of long-range coupling from the cytosolic sensor domain to the selectivity filter in TREK K2P channels
20. Dynamic interplay of the proximal C-terminus and selectivity filter reveals gating and pharmacological modulation mechanisms in TREK K2P channels
21. 5-Hydroxydecanoate and coenzyme A are inhibitors of native sarcolemmal KATP channels in inside-out patches
22. Side pockets provide the basis for a new mechanism of Kv channel–specific inhibition
23. Identification of the muscarinic pathway underlying cessation of sleep-related burst activity in rat thalamocortical relay neurons
24. The pore structure and gating mechanism of K2P channels
25. RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels
26. H Bonding at the Helix-Bundle Crossing Controls Gating in Kir Potassium Channels
27. Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel
28. Molecular basis of inward rectification: polyamine interaction sites located by combined channel and ligand mutagenesis
29. Functional conversion between A-type and delayed rectifier [K.sup.+] channels by membrane lipids
30. Activation of the alkaline-activated K2P K+ channel talk-2 requires opening of two functionally coupled gates
31. Inward rectification in KATP channels: a pH switch in the pore
32. Random mutagenesis screening indicates the absence of a separate H+-sensor in the pH-sensitive Kir channels
33. Long Chain CoA Esters as Competitive Antagonists of Phosphatidylinositol 4,5-Bisphosphate Activation in Kir Channels
34. Cytoplasmic accumulation of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels
35. Phosphatidylinositol 4,5-Bisphosphate (PIP2) Modulation of ATP and pH Sensitivity in Kir Channels: A TALE OF AN ACTIVE AND A SILENT PIP2 SITE IN THE N TERMINUS
36. The inward rectification mechanism of the HERG cardiac potassium channel
37. Gating of Ca2+-Activated K+ Channels Controls Fast Inhibitory Synaptic Transmission at Auditory Outer Hair Cells
38. Structural Basis for Gating of the Two-Pore Domain K+ (K2P) Channels TASK-1 and TALK-2
39. K ATP channels: Linker between phospholipid metabolism and excitability
40. NMR Structure and Functional Characteristics of the Hydrophilic N Terminus of the Potassium Channel β-Subunit Kvβ1.1
41. Erratum: The pore structure and gating mechanism of K2P channels
42. Characterisation of the Versatile Gating Behaviour in Talk-2 K2P Channels
43. A Pharmacological Masterkey Mechanism to Unlock the Selectivity Filter Gate in K+ Channels
44. The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function.
45. Bidirectional control of Kir-channel activity by phosphoinositides and LC-acyl-CoA esters
46. Silver as a Probe of Selectivity Filter Gating in TREK-1 K2P Channels
47. Polymodal Gating of the TREK-2 K2P Potassium Channel Involves Structurally Distinct Open States
48. Liposome-Based in Vitro Biosynthesis of Two-Pore Domain Potassium Channels for Functional Studies
49. A Non-Canonical Voltage Sensor Controls Gating in K2P K+ Channels
50. Sensing the Electrochemical K+ Gradient: The Voltage Gating Mechanism in K2P Potassium Channels
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