1,736 results on '"Barbon, A"'
Search Results
2. Reliability and Confidence of Dynamic Imaging Grade of Swallowing Toxicity (DIGEST) Rating Among Research and Clinical Speech Pathologists Before and After Implementation of a Training Manual: A Multi-site Study
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Barbon, C. E. A., Warneke, C. L., Ledger, B., Rogus-Pulia, N., Cunningham, L., Coyle, J. L., Levesque-Boissonneault, C., Alvarez, C., Valencia, D., and Hutcheson, K. A.
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- 2024
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3. Effects of Statistical Practices for Longitudinal Group Comparison of the Penetration-Aspiration Scale on Power and Effect Size Estimation: A Monte Carlo Simulation Study
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Borders, James C., Grande, Alessandro A., Barbon, Carly E. A., Hutcheson, Katherine A., and Troche, Michelle S.
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- 2024
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4. Primary lymphoma of bone of the little finger: a case report and review of the literature
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Barbon, Dennis A., Williams, Todd P., Hulse, Hailey B., and Hansford, Barry G.
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- 2024
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5. Clinical Implementation of DIGEST as an Evidence-Based Practice Tool for Videofluoroscopy in Oncology: A Six-Year Single Institution Implementation Evaluation
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Hutcheson, Katherine A., Aldridge, Ella F., Warneke, Carla L., Buoy, Sheila N., Tang, Xiaohui, Macdonald, Cameron, Alvarez, Clare P., Barringer, Denise A., Barbon, Carly E.A., Ebersole, Barbara M., McMillan, Holly, and Montealegre, Jane R.
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- 2024
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6. Innate immune response in COVID-19: single-cell multi-omics profile of NK lymphocytes in a clinical case series
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Silvia Barbon, Fabrizio Armellin, Verena Passerini, Sergio De Angeli, Simona Primerano, Laura Del Pup, Elisabetta Durante, Veronica Macchi, Raffaele De Caro, Pier Paolo Parnigotto, Arianna Veronesi, and Andrea Porzionato
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COVID-19 ,Natural killer lymphocytes ,Innate immune response ,Single-cell multi-omics analysis ,BD Rhapsody system ,Medicine ,Cytology ,QH573-671 - Abstract
Abstract Background COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) represents the biggest global health emergency in recent decades. The host immune response to SARS-CoV-2 seems to play a key role in disease pathogenesis and clinical manifestations, with Natural Killer (NK) lymphocytes being among the targets of virus-induced regulation. Methods This study performed a single-cell multi-omics analysis of transcripts and proteins of NK lymphocytes in COVID-19 patients, for the characterization of the innate immunological response to infection. NK cells were isolated from peripheral blood samples collected from adult subjects divided into 3 study groups: (1) non-infected subjects (Naïve group, n = 3), (2) post COVID-19 convalescent subjects (Healed group, n = 3) and (3) patients that were vaccinated against SARS-CoV-2 (Vaccine group, n = 3). Cells were then analysed by the BD Rhapsody System for the single-cell multi-omics investigation of transcriptome and membrane proteins. Results The bioinformatic analysis identified 5 cell clusters which differentially expressed gene/protein markers, defining NK cell subsets as “Active NK cells” and “Mature NK cells”. Calculating the relative proportion of each cluster within patient groups, more than 40% of the Naïve group cell population was found to belong to Mature NKs, whereas more than 75% of the Vaccine group cell population belonged to the cluster of Active NKs. Regarding the Healed group, it seemed to show intermediate phenotype between Active and Mature NK cells. Differential expression of specific genes, proteins and signaling pathways was detected comparing the profile of the 3 experimental groups, revealing a more activated NK cell phenotype in vaccinated patients versus recovered individuals. Conclusions The present study detected differential expression of NK cell markers in relation to SARS-CoV-2 infection and vaccine administration, suggesting the possibility to identify key molecular targets for clinical-diagnostic use of the individual response to viral infection and/or re-infection.
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- 2024
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7. Exploring the influence of tooth, ceramic, and resin luting agent variations on laminate veneer optical characteristics: a prospective clinical investigation
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Perroni, Ana Paula, Barbon, Fabíola Jardim, Chaves, Eduardo Trota, Alberton da Silva, Simone, de Moraes, Rafael Ratto, and Boscato, Noéli
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- 2024
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8. Innate immune response in COVID-19: single-cell multi-omics profile of NK lymphocytes in a clinical case series
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Barbon, Silvia, Armellin, Fabrizio, Passerini, Verena, De Angeli, Sergio, Primerano, Simona, Del Pup, Laura, Durante, Elisabetta, Macchi, Veronica, De Caro, Raffaele, Parnigotto, Pier Paolo, Veronesi, Arianna, and Porzionato, Andrea
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- 2024
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9. Efficiency of Cornstalk-Derived Activated Carbon in Treating Cephalexin-Contaminated Water
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Rosil, Shaina Mae, Zulita, Mariah Juville, Tarucan, Stephanie, Barbon, Jollie, Pagalan, Jr., Efren, Tizo, Maribel, Labadan, Rensel Jay, and Arazo, Renato
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- 2024
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10. 100 anastomoses: a two-year single-center experience with robotic-assisted micro- and supermicrosurgery for lymphatic reconstruction
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von Reibnitz, Donata, Weinzierl, Andrea, Barbon, Carlotta, Gutschow, Christian A., Giovanoli, Pietro, Grünherz, Lisanne, and Lindenblatt, Nicole
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- 2024
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11. Better trees: an empirical study on hyperparameter tuning of classification decision tree induction algorithms
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Gomes Mantovani, Rafael, Horváth, Tomáš, Rossi, André L. D., Cerri, Ricardo, Barbon Junior, Sylvio, Vanschoren, Joaquin, and Carvalho, André C. P. L. F. de
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- 2024
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12. Robotic-assisted Lymphovenous Anastomosis of the Central Lymphatic System
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Lisanne Grünherz, MD, Andrea Weinzierl, MD, Christian Alexander Gutschow, MD, Gilbert Dominique Puippe, MD, Ralph Gnannt, MD, Donata von Reibnitz, MD, Epameinondas Gousopoulos, MD, PhD, Carlotta Barbon, MD, Pietro Giovanoli, MD, Claus Christian Pieper, MD, and Nicole Lindenblatt, MD
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Surgery ,RD1-811 - Abstract
Background:. Recent advances in robotic microsurgery have enabled the application of robotic technology in central lymphatic reconstruction. Although the use of microsurgical robots demands careful consideration of associated costs and potentially prolonged operating times, it may offer improved surgical approaches and enhanced accessibility to deeper anatomical structures such as the thoracic duct (TD). Methods:. We report on successful reconstruction of the central lymphatic system using the Symani Surgical System in four patients with lesions of the central lymphatic system. The patients were of different age (range: 8 mo–60 y) and had variable conditions, including central conducting lymphatic anomaly and other rare anomalies of the central lymphatic pathways. Results:. Depending on the underlying pathology, a cervical access (n = 1) or median laparotomy (n = 3) was chosen to access the TD and perform anastomosis with a nearby vein. In all patients, anastomoses were patent, and chyle leakage decreased postoperatively. From a surgical perspective, the Symani Surgical System improved the precision of the microsurgeon and accessibility to the deep-lying TD. Conclusion:. Considering the high morbidity and rarity of pathologies of the central lymphatic system, robotic-assisted microsurgery holds substantial promise in expanding and improving the microsurgical treatment for central lymphatic anomalies.
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- 2024
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13. Partially oxidized polyvinyl alcohol + functionalized water soluble multiwalled carbon nanotubes: A new conductive nanocomposite material with promising implications for neuroregeneration
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Elena Stocco, Silvia Barbon, Ludovica Ceroni, Marta Confalonieri, Giada Pulzato, Samuel Pressi, Alice D'Osualdo, Marta Contran, Rafael Boscolo-Berto, Cesare Tiengo, Silvia Todros, Piero G. Pavan, Veronica Macchi, Raffaele De Caro, Laura Calvillo, Enzo Menna, and Andrea Porzionato
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Multiwalled carbon nanotubes ,Oxidized polyvinyl alcohol ,Nanocomposite hydrogel ,Electroconductivity ,Peripheral nerve regeneration ,Materials of engineering and construction. Mechanics of materials ,TA401-492 - Abstract
Carbon nanotubes (CNT) are promising electroconductive nano-scale materials for neuroregeneration. Herein, we report on a new electroconductive composite scaffold made of the polymer 1% oxidized polyvinyl alcohol (OxPVA) combined with functionalized water soluble multiwalled CNT (OxPVA + MWCNT-S) (diazotization reaction). Preliminarily, MWCNT-S were characterized to evaluate the reaction outcome, the degree of functionalization and the dispersibility in water. Thereafter, OxPVA + MWCNT-S nanocomposite membranes were fabricated and analyzed for physicochemical properties (Raman spectroscopy, thermal decomposition, calorimetric properties, electroconductivity), macroscopic appearance and ultrastructure, mechanical behavior, in vitro cytotoxicity and in vivo biocompatibility. In parallel, OxPVA + MWCNT-S membranes with a linear pattern were also developed and analyzed for interaction with SH-SY5Y cells. Compared to OxPVA, the presence of MWCNT-S (only 0.016 wt%) significantly increased polymer conductivity and imparted a certain porosity without altering mechanical behaviour, as corroborated by uniaxial tensile tests. Neither cytotoxicity nor local signs of inflammation were detected in vitro and after subcutaneous implantation (14 and 42 days), proving composite material biocompatibility. OxPVA + MWCNT-S nanocomposite revealed as promising for future electroconductive conduits free from toxic effects amenable to CNT agglomeration within the polymer. Ideally, nerve lesions with wide gaps, may be effectively supported by those “active” devices, overcoming limitations of the available ones. Despite preliminary data, the presence of a linear pattern confirmed to have a beneficial effect over the scaffold/cells interaction.
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- 2024
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14. Stress, microRNAs, and stress-related psychiatric disorders: an overview
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Musazzi, Laura, Mingardi, Jessica, Ieraci, Alessandro, Barbon, Alessandro, and Popoli, Maurizio
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- 2023
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15. Electron spin polarization in the triplet state of methoxy-substituted phosphorus(V) tetraphenyl porphyrins
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D. Panariti, B.J. Bayard, A. Barbon, Y.E. Kandrashkin, P.K. Poddutoori, A. van der Est, and M. Di Valentin
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EPR ,Triplet state ,Phosphorus porphyrins ,Electron spin polarization ,Radical hyperpolarization ,Intersystem crossing ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 ,Physics ,QC1-999 - Abstract
Photoexcited triplet states of porphyrins are of great relevance in various applications due to their high yield, long lifetime, and strong electron spin polarization. This study delves into properties and spin dynamics of the triplet state of a series of hypervalent phosphorus(V) porphyrins. Transient Electron Paramagnetic Resonance (TrEPR) measurements, supported by quantum chemical calculations as well as by optical absorption/luminescence experiments, reveal that, unlike singlet states, the lowest triplet state does not exhibit charge-transfer (CT) character upon photoexcitation. However, the presence of excited CT singlet states alters the intersystem crossing in phosphorus(V) porphyrins, leading to a sign change in the initial multiplet polarization of the photoexcited triplet state. TrEPR results further demonstrate that significant net polarization develops in the triplet states of the phosphorus(V) porphyrins due to the dynamic Jahn-Teller effect. Yet, this effect remains largely unaffected by differences in their molecular structures.
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- 2024
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16. In vivo liver targeted genome editing as therapeutic approach: progresses and challenges
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Chiara Simoni, Elena Barbon, Andrés F. Muro, and Alessio Cantore
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liver ,genome editing ,liver directed genome editing ,delivery methods ,lipid nano particle ,viral vectors ,Biotechnology ,TP248.13-248.65 ,Genetics ,QH426-470 - Abstract
The liver is an essential organ of the body that performs several vital functions, including the metabolism of biomolecules, foreign substances, and toxins, and the production of plasma proteins, such as coagulation factors. There are hundreds of genetic disorders affecting liver functions and, for many of them, the only curative option is orthotopic liver transplantation, which nevertheless entails many risks and long-term complications. Some peculiar features of the liver, such as its large blood flow supply and the tolerogenic immune environment, make it an attractive target for in vivo gene therapy approaches. In recent years, several genome-editing tools mainly based on the clustered regularly interspaced short palindromic repeats associated protein 9 (CRISPR-Cas9) system have been successfully exploited in the context of liver-directed preclinical or clinical therapeutic applications. These include gene knock-out, knock-in, activation, interference, or base and prime editing approaches. Despite many achievements, important challenges still need to be addressed to broaden clinical applications, such as the optimization of the delivery methods, the improvement of the editing efficiency, and the risk of on-target or off-target unwanted effects and chromosomal rearrangements. In this review, we highlight the latest progress in the development of in vivo liver-targeted genome editing approaches for the treatment of genetic disorders. We describe the technological advancements that are currently under investigation, the challenges to overcome for clinical applicability, and the future perspectives of this technology.
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- 2024
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17. Insomnia Polygenic Component on Attention Deficit-Hyperactivity Disorder: Exploring this Association Using Genomic Data from Brazilian Families
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Marina Xavier Carpena, Brenda Barbon Fraga, Thais Martins-Silva, Angélica Salatino-Oliveira, Júlia Pasqualini Genro, Guilherme V. Polanczyk, Cristian Zeni, Marcelo Schmitz, Rodrigo Chazan, Mara Helena Hutz, Luis Augusto Rohde, and Luciana Tovo-Rodrigues
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polygenic risk score ,insomnia ,attention-deficit/hyperactivity disorder ,Psychology ,BF1-990 ,Consciousness. Cognition ,BF309-499 - Abstract
Introduction Insomnia is highly prevalent among individuals with Attention-Deficit/Hyperactivity Disorder (ADHD). However, the biological mechanisms shared between both conditions is still elusive. We aimed to investigate whether insomnia's genomic component is able to predict ADHD in childhood and adolescence.
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- 2024
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18. Commentary: Techniques and graft materials for repairing peripheral nerve defects
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Elena Stocco, Silvia Barbon, Aron Emmi, Cesare Tiengo, Raffaele De Caro, Veronica Macchi, and Andrea Porzionato
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peripheral nerve injury ,nerve conduits ,luminal filler ,bioactivation ,tissue engineering ,Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
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19. Peculiarities in Rabi oscillations for fast-relaxing electron spins
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Barbon, Antonio, Rusetsky, Grigory A., Linarello, Sveva, Strzelczyk, Roman, and Fedaruk, Ryhor
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- 2024
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20. Analysis of different outcome parameters and quality of life after different techniques of free vascularized lymph node transfer
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Grünherz, Lisanne, Barbon, Carlotta, von Reibnitz, Donata, Gousopoulos, Epameinondas, Uyulmaz, Semra, Giovanoli, Pietro, Vetter, Diana, Gutschow, Christian Alexander, and Lindenblatt, Nicole
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- 2024
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21. An acceptance and commitment therapy and mindfulness group intervention for the psychological and physical well-being of adults with body mass indexes in the overweight or obese range: The Mind&Life randomized controlled trial
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Iturbe, Idoia, Urkia-Susin, Iratxe, Echeburúa, Enrique, Barbón, Ane Miren, and Maiz, Edurne
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- 2024
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22. Interpretation and explanation of computer vision classification of carambola (Averrhoa carambola L.) according to maturity stage
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de Moraes, Ingrid Alves, Barbon Junior, Sylvio, and Barbin, Douglas Fernandes
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- 2024
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23. Partially oxidized polyvinyl alcohol + functionalized water soluble multiwalled carbon nanotubes: A new conductive nanocomposite material with promising implications for neuroregeneration
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Stocco, Elena, Barbon, Silvia, Ceroni, Ludovica, Confalonieri, Marta, Pulzato, Giada, Pressi, Samuel, D'Osualdo, Alice, Contran, Marta, Boscolo-Berto, Rafael, Tiengo, Cesare, Todros, Silvia, Pavan, Piero G., Macchi, Veronica, De Caro, Raffaele, Calvillo, Laura, Menna, Enzo, and Porzionato, Andrea
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- 2024
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24. Portable near infrared (NIR) spectrometer coupled with machine learning to classify milk with subclinical mastitis
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da Silva Pereira, Erik, Cruz-Tirado, J.P., Lourenço Crippa, Bruna, Martins Morasi, Rafaela, Milagres de Almeida, Jaqueline, Fernandes Barbin, Douglas, Barbon Junior, Sylvio, and Cristina Cirone Silva, Nathalia
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- 2024
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25. A two-context-aware approach for navigation: A case study for vehicular route recommendation
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Barbon, Rafael S., Madeira, Edmundo R.M., and Akabane, Ademar T.
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- 2025
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26. Machine learning predictions of onset and oxidation potentials for methanol and ethanol electrooxidation: Comprehensive analysis and experimental validation
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von Zuben, Theodora Wrobel, Salles, Airton Gonçalves, Jr., Bonacin, Juliano Alves, and Barbon, Sylvio, Junior
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- 2025
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27. Hair cortisol measurement: A systematic review of current practices and a proposed checklist for reporting standards
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Martins-Silva, Thais, Martins, Rafaela Costa, Murray, Joseph, Carvalho, Andressa Marques, Rickes, Letícia Neutzling, Corrêa, Beatriz de Freitas, Fraga, Brenda Barbon, Brum, Clarice Brinck, Freitas, Deise Farias, Meyer, Fernando Diógenes Teixeira, Carpena, Marina Xavier, Goularte, Laura Moreira, Gonzalez, Andrea, Oliveira, Isabel Oliveira de, and Tovo-Rodrigues, Luciana
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- 2025
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28. Analyzing fatigue in dynamic exercise through electromyography signals and similarity metrics
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Schiaber, Pâmela de Souza, Scalassara, Paulo Rogério, Endo, Wagner, Agulhari, Cristiano Marcos, Altimari, Leandro Ricardo, and Barbon, Sylvio, Júnior
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- 2025
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29. Unsupervised Tuning for Drift Detectors Using Change Detector Segmentation
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Ricardo Petri Silva, Sylvio Barbon Junior, Bruno Bogaz Zarpelao, and Leonimer Flavio De Melo
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Algorithm tuning ,concept drift ,signal drift ,drift detector ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Concept drifts can occur due to various factors such as changes in the environment or sensor degradation, posing significant challenges to machine learning systems by potentially skewing decision-making processes. Therefore, detecting drifts is essential to maintain the integrity and functionality of these systems. Automatic detectors based on statistical information are usually used to accomplish this task. Optimizing drift detectors through tuning is crucial for effective concept drift analysis. However, relying on user expertise or labeled data for supervised tuning can be challenging. In such cases, the use of unsupervised tuning methods becomes a suitable alternative to adapt detectors to evolving data distributions. To address this gap in the literature an unsupervised tuning method was proposed, leveraging a time series segmentation method. This innovative approach aims to alleviate the reliance on labeled data or user expertise traditionally associated with supervised methods, offering a more adaptive and automated means of tuning detectors. Our results demonstrate that our proposed approach outperforms the default configuration in most evaluated cases. Furthermore, we show that our approach can improve the hyperparameter tuning process when the type of drift is known including supervised methods such as Random Search tuning. By adopting our approach, we can achieve better performance in drift detection and improve the accuracy and reliability of systems that rely on this critical task.
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- 2024
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30. Tuning Machine Learning to Address Process Mining Requirements
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Paolo Ceravolo, Sylvio Barbon Junior, Ernesto Damiani, and Wil Van Der Aalst
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Process mining ,machine learning ,non-parametric distribution ,concurrency ,non-stationary ,zero-shot learning ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Machine learning models are routinely integrated into process mining pipelines to carry out tasks like data transformation, noise reduction, anomaly detection, classification, and prediction. Often, the design of such models is based on some ad-hoc assumptions about the corresponding data distributions, which are not necessarily in accordance with the non-parametric distributions typically observed with process data. Moreover, mainstream machine-learning approaches tend to ignore the challenges posed by concurrency in operational processes. Data encoding is a key element to smooth the mismatch between these assumptions but its potential is poorly exploited. In this paper, we argue that a deeper understanding of the challenges associated with training machine learning models on process data is essential for establishing a robust integration of process mining and machine learning. Our analysis aims to lay the groundwork for a methodology that aligns machine learning with process mining requirements. We encourage further research in this direction to advance the field and effectively address these critical issues.
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- 2024
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31. Haemosporidian parasite infections of Malagasy Philepittidae and Nectariniidae are driven by phylogeny rather than ecology
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Hannah Barbon, Jean-Louis Berthoud, Friederike Woog, Sandrine Musa, and L. C. Ranford-Cartwright
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Cinnyris spp ,filarioid nematodes ,Haemoproteus ,Leucocytozoon ,Nectariniidae ,Neodrepanis coruscans ,Philepitta castanea ,Plasmodium ,Trypanosoma ,Biochemistry ,QD415-436 ,Infectious and parasitic diseases ,RC109-216 ,Microbiology ,QR1-502 - Abstract
The nectarivorous common sunbird asity (Neodrepanis coruscans) is phylogenetically closely related to the frugivorous velvet asity (Philepitta castanea), yet it shares similar habitat and foraging behaviour as the Malagasy sunbirds (Cinnyris spp.). As ecological factors have been shown to influence blood parasite prevalence, it should be tested whether parasite abundance, prevalence and diversity of N. coruscans are more similar to the sunbirds than to its relative. Therefore, blood samples (n = 156) and smears (n = 60) were tested for different blood parasites (Haemosporida, trypanosomes, filarioid nematodes) using molecular and microscopic methods. High prevalence of haemosporidian parasites was observed in all bird taxa, with rates ranging from 23% in N. coruscans to 84.6% in C. notatus. The Malagasy Cinnyris spp. exhibited a high occurrence of mixed haemosporidian infections (>76%) with various specialized lineages. Within the Philepittidae family, no Haemoproteus infection was detected and just a few cases of mixed infections. Nectariniidae species predominantly had specialized haemosporidian lineages, while Philepittidae had infections mainly caused by generalist lineages. These findings emphasize the diverse range of blood parasites in Nectariniidae, while additionally highlighting the high diversity of trypanosomes and filarioid nematodes in Philepittidae. Additionally, several newly discovered haemosporidian lineages, Trypanosoma isolates and filarioid nematode isolates were identified. Notably, Philepittidae exhibited a lower prevalence of avian haemosporidian parasites compared to Nectariniidae, possibly due to potential resistance mechanisms. Despite N. coruscans sharing similar habitat and behavioural ecology with both Cinnyris spp., it closely resembles its relative, P. castanea, in all aspects of haemosporidian parasitism.
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- 2023
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32. Electron spin polarization in the triplet state of methoxy-substituted phosphorus(V) tetraphenyl porphyrins
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Panariti, D., Bayard, B.J., Barbon, A., Kandrashkin, Y.E., Poddutoori, P.K., van der Est, A., and Di Valentin, M.
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- 2024
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33. Deep computer vision system and explainable artificial intelligence applied for classification of dragon fruit (Hylocereus spp.)
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da Silva Ferreira, Marcus Vinicius, Barbon Junior, Sylvio, Turrisi da Costa, Victor G., Barbin, Douglas Fernandes, and Lucena Barbosa Jr, José
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- 2024
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34. How people interact with a chatbot against disinformation and fake news in COVID-19 in Brazil: The CoronaAI case
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Abonizio, Hugo Queiroz, Barbon, Ana Paula Ayub da Costa, Rodrigues, Renne, Santos, Mayara, Martínez-Vizcaíno, Vicente, Mesas, Arthur Eumann, and Barbon Junior, Sylvio
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- 2023
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35. Histopathological characterization and grading of chronic enterocolitis in Sulawesi crested macaques (Macaca nigra)
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Van de Weyer, Yannick, Howard, Mark R., Stidworthy, Mark F., Barbon, Alberto R., Chantrey, Julian, Tahas, Stamatios A., Wrigglesworth, Ethan, Rowden, Lewis J., Guthrie, Amanda, and Spiro, Simon
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- 2024
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36. Changes at glutamate tripartite synapses in the prefrontal cortex of a new animal model of resilience/vulnerability to acute stress
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Bonifacino, Tiziana, Mingardi, Jessica, Facchinetti, Roberta, Sala, Nathalie, Frumento, Giulia, Ndoj, Elona, Valenza, Marta, Paoli, Caterina, Ieraci, Alessandro, Torazza, Carola, Balbi, Matilde, Guerinoni, Michele, Muhammad, Nadeem, Russo, Isabella, Milanese, Marco, Scuderi, Caterina, Barbon, Alessandro, Steardo, Luca, Bonanno, Giambattista, Popoli, Maurizio, and Musazzi, Laura
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- 2023
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37. Treatment of infantile-onset Pompe disease in a rat model with muscle-directed AAV gene therapy
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Sergio Muñoz, Joan Bertolin, Veronica Jimenez, Maria Luisa Jaén, Miquel Garcia, Anna Pujol, Laia Vilà, Victor Sacristan, Elena Barbon, Giuseppe Ronzitti, Jihad El Andari, Warut Tulalamba, Quang Hong Pham, Jesus Ruberte, Thierry VandenDriessche, Marinee K. Chuah, Dirk Grimm, Federico Mingozzi, and Fatima Bosch
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Glycogen metabolism ,Myopathies ,Pompe disease ,Rat model ,Gene therapy ,AAV ,Internal medicine ,RC31-1245 - Abstract
Objective: Pompe disease (PD) is caused by deficiency of the lysosomal enzyme acid α-glucosidase (GAA), leading to progressive glycogen accumulation and severe myopathy with progressive muscle weakness. In the Infantile-Onset PD (IOPD), death generally occurs
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- 2024
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38. Benefits of robotic-assisted lymphatic microsurgery in deep anatomical planes
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Andrea Weinzierl, Carlotta Barbon, Epameinondas Gousopoulos, Donata von Reibnitz, Pietro Giovanoli, Lisanne Grünherz, and Nicole Lindenblatt
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Lymphatic surgery ,Microsurgery ,Robotic microsurgery ,Robotic-assisted microsurgery ,Central lymphatic surgery ,Surgery ,RD1-811 - Abstract
Summary: Micro- and supermicrosurgeries have become standard techniques for lymphatic reconstruction. As increasingly smaller vessels are being targeted, robotic-assisted surgery has emerged as a new approach to push reconstructive limits owing to its ability of motion scaling and providing better accessibility of deep anatomical regions. The precision of the robot is achieved at the expense of operating speed among other variables; therefore, the surgeon must weigh the enhanced dexterity against the additional operating time and cost required for the robotic surgical system itself to ensure optimal resource utilization.Here we present a case series of 8 patients who underwent robot-assisted lymphatic microsurgery for omental flap transfer to the axilla and lympho-venous anastomosis. The Symani® Surgical System was used with a conventional microscope or 3D exoscope. The use of 3D exoscope provided clear benefits in terms of surgeon positioning. Moreover, access to the recipient vessels near the thoracic wall was significantly improved with the robotic setup. In addition, suture precision was excellent, resulting in patent anastomoses. Operating time for anastomosis was comparable to that for manual anastomosis and demonstrated a steep learning curve.The benefits of robotic systems in operating fields with good exposure require further evaluation. However, owing to longer instruments, additional stability, dexterity, and motion precision, robotic systems offer a marked advantage for operating in deep anatomical planes and on small structures. A potentially new field for the implementation of robotic surgery is central lymphatic reconstruction. Progress in terms of operating time and cost is crucial, and future research should validate the effectiveness of robotic-assisted surgery in larger clinical studies.
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- 2023
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39. Treatment of infantile-onset Pompe disease in a rat model with muscle-directed AAV gene therapy
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Muñoz, Sergio, Bertolin, Joan, Jimenez, Veronica, Jaén, Maria Luisa, Garcia, Miquel, Pujol, Anna, Vilà, Laia, Sacristan, Victor, Barbon, Elena, Ronzitti, Giuseppe, El Andari, Jihad, Tulalamba, Warut, Pham, Quang Hong, Ruberte, Jesus, VandenDriessche, Thierry, Chuah, Marinee K., Grimm, Dirk, Mingozzi, Federico, and Bosch, Fatima
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- 2024
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40. Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial
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Faust, Saul N, Haynes, Richard, Jones, Christine E, Staplin, Natalie, Whittaker, Elizabeth, Jaki, Thomas, Juszczak, Ed, Spata, Enti, Wan, Mandy, Bamford, Alasdair, Dimitri, Paul, Finn, Adam, Furness, John, Ramanan, Athimalaipet V, Gale, Christopher, Cathie, Katrina, Drysdale, Simon, Bernatoniene, Jolanta, Murray, Clare, Roehr, Charles C, Fleming, Paul, Riordan, Andrew, Bandi, Srini, Jyothish, Deepthi, Evans, Jennifer, Emonts, Marieke, Kelly, Dominic, Pathan, Nazima, Davies, Patrick, Hague, Rosie, Pollock, Louisa, Semple, Malcolm G, Peto, Leon, Baillie, J Kenneth, Buch, Maya, Jeffery, Katie, Knight, Marian, Lim, Wei Shen, Montgomery, Alan, Mukherjee, Aparna, Mumford, Andrew, Rowan, Kathryn, Thwaites, Guy, Mafham, Marion, Emberson, Jonathan, Landray, Martin J, Horby, Peter W, Chappell, Lucy, Day, Jeremy, Dung, DV, Quang, NN, Binh, Prof, Burhan, E, Alisjahbana, B, Koirala, J, Basnet, S, Kestelyn, E, Basnyat, B, Gyanwali, P, Hamers, RL, Sandercock, P, Darbyshire, J, DeMets, D, Fowler, R, Lalloo, D, Munavvar, M, Roberts, I, Warris, A, Wittes, J, Craddock-Bamford, A, Barton, J, Basoglu, A, Brown, R, Brudlo, W, Denis, E, Fletcher, L, Howard, S, Musini, S, Taylor, K, Cui, G, Goodenough, B, King, A, Lay, M, Murray, D, Stevens, W, Wallendszus, K, Welsh, R, Crichton, C, Davies, J, Goldacre, R, Harper, C, Knight, F, Nunn, M, Salih, H, Welch, J, Campbell, M, Pessoa-Amorim, G, Zayed, M, Wiles, J, Bagley, G, Cameron, S, Chamberlain, S, Farrell, B, Freeman, H, Kennedy, A, Whitehouse, A, Wilkinson, S, Wood, C, Reith, C, Davies, K, Halls, H, Holland, L, Truell, R, Wilson, K, Lingwood, Emma, Howie, L, Lunn, M, Rodgers, Penelope, Amuasi, J, Baird, K, Bao, T, Bittaye, M, Bonney, J, D'Alessandro, U, Dhimal, M, Huyen, T, Jagne, A, Karkey, A, Maiga, O, Matey, E, Nadjm, B, Nel, J, Pant, S, Puspatriani, K, Rahardjani, M, Raijal, S, Rees, H, Rimainar, A, Roberts, C, Rocca, A, Shrestha, S, Usuf, E, Vidaillic, C, Wulandari, F, Alexander, A, Amezaga, M, Armah, C, Asghar, A, Aubrey, P, Barker-Williams, K, Barnard, A, Bartholomew, J, Beaumont-Jewell, D, Beddows, S, Beety, J, Birch, C, Boyle, P, Brend, M, Brookes, M, Callens, C, Campbell, D, Campbell, H, Cate, H, Chambers, E, Chapman, K, Coe, A, Collins, J, Crawshaw, S, Das, S, De Soyza, A, Denton, E, Dicks, P, Dolman, M, Donaldson, K, Dowden, L, Dowling, S, Drake, C, Duckles-Leech, H, Duffy, H, Gerdes, L, Gibbons, K, Gill, L, Gilmour, K, Goodwin, J, Graham, J, Green, C, Hall, C, Hall, A, Hampshire, K, Hanson, J, Harman, T, Harper, H, Harrison, S, Hicks, J, Hodgson, H, Hough, M, Jackson, S, Johnson, G, Kirk, J, Lemoine, N, Levett, C, Lock, S, Lockett, T, Logan, M, Lomme, K, Luo, J, McMillan, N, Membrey, H, Mguni, N, Minton, J, Monaghan, H, Murphy, S, Muzengi, N, Naz, M, Nickson, I, Odam, M, Ohia, U, Okell, E, Oliver, A, Pearson, K, Pine, K, Pleass, R, Porter, D, Porter, L, Potter, A, Poustie, V, Pratt, S, Price, A, Priest, A, Rodgers, A, Rook, C, Ryan, P, Sam, S, Sharratt, P, Sheffield, J, Shenton, J, Shirley, K, Skinner, T, Slade, H, Sutu, M, Taylor, J, Thomas, E, Tinkler, H, Unsworth, A, Usher, R, van't Hoff, W, Walker, S, Walters, J, Walton, E, Warmington, J, Wayman, E, Williams, P, Williamson, J, Williamson, D, Yelnoorkar, F, Knight, M, Hodson, K, Pavord, S, Williamson, C, Bowman, L, Chen, F, Clarke, R, Goonasekara, M, Herrington, W, Judge, P, Ng, S, Preiss, D, Sammons, E, Zhu, D, Arkley, C, Bowker, P, Bruce, J, Byrne-Watts, V, Chapman, G, Coleman, G, Denwood, T, Gray, J, Harrison, D, Mather, N, Pinches, H, Rees, A, Rees, S, Turner, G, Abani, O, Abbas, A, Abbas, F, Abbas, J, Abbas, K, Abbas, M, Abbasi, S, Abbass, H, Abbott, A, Abdallah, N, Abdelaziz, A, Abdelfattah, M, Abdelqader, B, Abdul, A, Abdul, B, Abdul, S, Abdul Rasheed, A, Abdulakeem, A, Abdul-Kadir, R, Abdullah, A, Abdulmumeen, A, Abdul-Raheem, R, Abdulshukkoor, N, Abdusamad, K, Abed El Khaleq, Y, Abedalla, M, Abeer Ul Amna, A, Abel, L, Abernethy, K, Abeywickrema, M, Abhinaya, C, Aboaba, A, Aboagye-Odei, A, Aboelela, H, Abo-Leyah, H, Abouelela, K, Abou-Haggar, A, Abouibrahim, M, Abousamra, A, Abouzaid, M, Abraham, M, Abraham, T, Abraheem, A, Abrams, J, Abrams, R, Abu, H, Abu-Arafeh, A, Abubacker, S, Abung, A, Abusamra, Y, Aceampong, Y, Achara, A, Acharya, D, Acheampong, S, Acheampong, P, Acheson, J, Achieng, S, Acosta, A, Acquah, R, Acton, C, Adabie-Ankrah, J, Adair, P, Adam, F, Adam, M, Adamali, H, Adamczyk, M, Adams, C, Adams, D, Adams, K, Adams, L, Adams, N, Adams, R, Adams, T, Adamu-Ikeme, L, Adati, K, Adcock, K, Addo, A, Adeagbo, O, Adebiyi, A, Adedeji, O, Adegeye, Y, Adegoke, K, Adell, V, Adenwalla, S, Adeoye, F, Adesemoye, O, Adewunmi, E, Adeyanju, A, Adeyemi, J, Adeyemo, T, Adhikary, R, Aditya, A, Adkins, G, Adnan, A, Aeron-Thomas, J, Affleck, D, Afnan, C, Afridi, M, Aftab, Z, Agarwal, M, Agbeko, R, Agbo, C, Aggarwal, S, Aghababaie, A, Aguilar Jimenez, L, Ahamed Sadiq, S, Ahammed Nazeer, M, Ahmed, A, Ahmed, B, Ahmed, F, Ahmed, H, Ahmed, I, Ahmed, K, Ahmed, L, Ahmad, M, Ahmed, N, Ahmed, O, Ahmed, R, Ahmad, S, Ahmed, S H, Ahmed Ali, R, Ahmed Mohamud, B, Ahmer, S, Ahonia, A, Aiken, C, Ail, D, Ainsworth, M, Aissa, M, Aitken, L, Ajay, B, Ajibode, A, Ajmi, A, Akhtar, N, Akili, S, Akinbiyi, B, Akindolie, O, Akinfenwa, Y, Akinkugbe, O, Akinpelu, I, Akram, M, Aktinade, O, Akudi, U, Al Aaraj, A, Al Balushi, A, Al Dakhola, M, Al Swaifi, A, Al-Abadi, E, Alabi, A, Aladangady, N, Alafifi, M, Alam, A, Alam, S, Al-Asadi, A, Alatzoglou, K, Albert, P, Albon, L, Alcala, A, Alcorn, G, Alcorn, S, Aldana, A, Alderdice, D, Aldesouki, A, Aldouri, R, Aldridge, J, Aldridge, N, Alegria, A, Alexander, C, Alexander, J, Alexander, P, Al-Fori, J, Alghazawi, L, Alhabsha, O, Al-Hakim, B, Alhameed, R, Al-Hayali, M, Al-Hity, S, Ali, A, Ali, F, Ali, J, Ali, M, Ali, N, Ali, O, Ali, R, Ali, S, Aliberti, E, Alin, J, Alina, A, Alipustain, A, Aliyuda, F, Alizaedeh, K, Al-Jibury, M, Al-Juboori, S, Al-Khalil, M, Alkhudhayri, A, Alkhusheh, M, Allan, F, Allan, N, Allanson, A, Allcock, R, Allen, E, Allen, J, Allen, K, Allen, L, Allen, P, Allen, R, Allen, S, Allen, T, Alli, A, Allison, K, Allman, B, Allsup, D, Allsop, H, Allsop, L, Almahroos, A, Al-Moasseb, H, Al-Obaidi, M, Alomari, L, Al-Rabahi, A, Al-Ramadhani, B, Al-Saadi, Z, Al-Sammarraie, R, Alshaer, I, Al-Shahi Salman, R, Al-Shamkhani, W, Alsheikh, F, Al-Sheklly, B, Altaf, S, Alty, A, Alvarez, M, Alvarez Corral, M, Alveyn, E, Alzetani, M, Amamou, S, Amar, N, Ambalavanan, S, Ambrogetti, R, Ambrose, C, Ameen, A, Ames, K, Amin, A, Amin, K, Amin, S, Amin, T, Amit, B, Amjad, A, Amjad, N, Amosun, V, Amsal, M, Amsha, K, Amutio Martin, N, Amy, P, Anada, A, Anand, A, Anandappa, S, Anantapatnaikuni, S, Anderson, E, Anderson, J, Anderson, L, Anderson, M, Anderson, N, Anderson, R, Anderson, S, Anderson, W, Andreou, P, Andrews, A, Andrews, J, Aneke, K, Ang, A, Ang, W, Angel, T, Angela, A, Angelini, P, Anguvaa, L, Anichtchik, O, Anim-Somuah, M, Aniruddhan, K, Annett, J, Anning, L, Anstey, P, Anstey, R, Anthony, A, Anthony-Pillai, A, Antill, P, Antonnia, Z, Anu, V, Anwar, M, Apetri, E, Apostolopoulos, A, Appleby, S, Appleyard, D, Aquino, M, Araba, B, Aransiola, S, Araujo, M, Archer, A, Archer, D, Archer, S, Arcoria, D, Ardley, C, Arias, A, Aribike, O, Arimoto, R, Armata, I, Armistead, J, Armitage, A, Armstrong, C, Armstrong, M, Armstrong, S, Armstrong, W, Armtrong, P, Arndt, H, Arnison-Newgass, C, Arnold, D, Arnold, R, Arnott, A, Arora, D, Arora, R, Arora, K, Arora, P, Arter, A, Arumaithurai, A, Arya, A, Arya, R, Asandei, D, Asghar, M, Ashab, M, Ashbrook-Raby, C, Ashby, H, Ashcroft, J, Ashcroft, S, Asher, G, Ashfak, Z, Ashfaq, A, Ashish, A, Ashley, D, Ashman-Flavell, S, Ashok, S, Ashour, A, Ashraf, S, Ashraf, M, Ashraq, M, Ashton, D, Ashton, S, Ashworth, A, Ashworth, F, Ashworth, R, Aslam, A, Aslam, I, Aslam, S, Aslett, L, Asogan, H, Asrar, A, Assaf, O, Astin-Chamberlain, R, Athorne, D, Atkins, B, Atkins, C, Atkins, S, Atkinson, J, Atkinson, V, Atomode, A, Atraskiewicz, B, Attia, A, Attubato, E, Attwood, M, Auer, Z, Aujayeb, A, Aung, A, Aung, H, Aung, K, Aung, N, Aung, Y, Aung, Z, Austin, E, Austin, K, Auwal, A, Avari, M, Avery, M, Aveyard, N, Avis, J, Aviss, G, Avram, C, Avram, P, Awadelkareem, A, Awadzi, G, Awaly, M, Awan, A, Awoseyila, A, Aya, A, Ayaz, E, Ayers, A, Azam, J, Azeem, A, Azharuddin, M, Aziz, A, Aziz, G, Aziz, I, Aziz, N, Azkoul, A, Azman Shah, A, Azzopardi, G, Azzoug, H, Babatunde, F, Babi, M, Babiker, B, Babington, G, Babirecki, M, Babores, M, Babs-Osibodu, A, Bacciarelli, S, Bachar, R, Bachour, M, Bacon, G, Bacon, J, Badal, B, Bader, M, Badhan, G, Badhrinarayanan, S, Bae, J, Baggaley, A, Baggott, A, Bagmane, D, Bagshaw, L, Bahadori, K, Bailey, A, Bailey, J, Bailey, K, Bailey, L, Bailey, M, Bailey, P, Bailey, S, Baillie, H, Baillie, J, Bain, J, Bains, V, Baird, D, Baird, E, Baird, S, Baird, T, Baird, Y, Bajandouh, A, Baker, D, Baker, E, Baker, J, Baker, K, Baker, M, Baker, R, Baker, T, Baker, V, Bakere, H, Bakerly, N, Baker-Moffatt, M, Bakhai, A, Bakhtiar, N, Bakoulas, P, Bakthavatsalam, D, Balachandran, N, Balan, A, Balasingam, P, Balaskas, T, Balasubramania, M, Balatoni, N, Balcombe, A, Baldwin, A, Baldwin, C, Baldwin, D, Baldwin, F, Baldwin-Jones, R, Bale, N, Balfour, J, Ball, R, Ball, M, Ballard, K, Balluz, I, Balmforth, C, Balogh, E, Baltmr, A, Baluwala, A, Bambridge, G, Bamford, P, Bamford, A, Bamgboye, A, Bancroft, H, Bancroft, E, Banda, J, Bandaru, K, Bandla, N, Bandyopadhyam, S, Banerjee, A, Banerjee, R, Bani-Saad, O, Banks, H, Banks, L, Banks, P, Bann, C, Bannister, H, Bannister, O, Banton, L, Baptist, M, Baqai, T, Baral, A, Baramova, D, Barbe, R, Barbon, E, Barbosa, M, Barbour, J, Barclay, A, Barclay, C, Bardsley, G, Bareford, S, Bari, S, Barker, A, Barker, D, Barker, E, Barker, H, Barker, J, Barker, L, Barker, O, Barkha, S, Barla, J, Barlow, G, Barlow, R, Barlow, V, Barnacle, J, Barnes, D, Barnes, N, Barnes, R, Barnes, T, Barnetson, C, Barnett, A, Barnett-Vanes, A, Barnsley, W, Barr, A, Barr, C, Barr, D, Barr, J, Barratt, N, Barratt, S, Barrera, M, Barrett, A, Barrett, F, Barrett, J, Barrett, S, Barrow, E, Bartlett, C, Bartlett, G, Bartlett, J, Bartlett, L, Bartley, S, Bartolmeu-Pires, S, Barton, A, Barton, G, Barton, L, Barton, R, Baruah, R, Baryschpolec, S, Bashir, H, Bashyal, A, Basker, B, Basran, A, Bassett, G, Bassett, J, Bassford, C, Bassoy, B, Bastion, V, Basumatary, A, Basvi, P, Bataduwaarachchi, V, Bate, T, Bateman, H, Bateman, K, Bateman, V, Bates, E, Bates, H, Bates, M, Bates, S, Batham, S, Batista, A, Batla, A, Batra, D, Batty, A, Batty, H, Batty, T, Baum, M, Baumbe, R, Bautista, C, Bawa, T, Bawa, F, Bawani, F, Bax, S, Baxter, M, Baxter, N, Baxter, Z, Bayes, H, Bayo, L-A, Bazari, F, Bazaz, R, Bazli, A, Beacham, L, Beadles, W, Beadon, K, Beak, P, Beale, A, Beard, K, Beardsal, K, Bearpark, J, Beasley, A, Beattie, S, Beaumont, K, Beaver, T, Beavis, S, Beazley, C, Beck, S, Beckett, V, Beckitt, R, Beckley, S, Beddall, H, Beeby, D, Beeby, S, Beech, G, Beecroft, M, Beer, S, Beer, N, Bega, G, Begg, A, Begg, S, Beghini, S, Begum, A, Begum, S, Behan, T, Behrouzi, R, Beishon, J, Beith, C, Belcher, J, Belfield, H, Belfield, K, Belgaumkar, A, Bell, D, Bell, G, Bell, J, Bell, L, Bell, N, Bell, P, Bell, S, Bellamu, J, Bellamy, M, Bellamy, T, Bellini, A, Bellis, A, Bellis, F, Bendall, L, Benesh, N, Benetti, N, Benham, L, Benison-Horner, G, Benkenstein, S, Benn, T, Bennett, A, Bennett, C, Bennett, D, Bennett, G, Bennett, K, Bennett, L, Bennett, M, Bennett, S, Bennion, K, Benoy, G, Benson, V, Bentley, A, Bentley, J, Benton, I, Beranova, E, Beresford, M, Bergin, C, Bergstrom, M, Berriman, T, Berry, Z, Best, K, Best, F, Bester, A, Beuvink, Y, Bevan, E, Bevins, S, Bewick, T, Bexley, A, Beyatli, S, Beynon, F, Bhadi, A, Bhagani, S, Bhakta, S, Bhalla, R, Bhandal, K, Bhandari, A, Bhandari, S, Bhanich Supapol, J, Bhanot, A, Bhanot, R, Bhasin, S, Bhat, A, Bhat, P, Bhatnagar, R, Bhatt, K, Bhayani, J, Bhojwani, D, Bhuie, P, Bhuiyan, S, Bibby, A, Bibi, F, Bibi, N, Bibi, S, Bicanic, T, Bidgood, S, Bigg, J, Biggs, S, Biju, A, Bikov, A, Billingham, S, Billings, J, Binns, A, BinRofaie, M, Bintcliffe, O, Birch, J, Birchall, K, Bird, S, Birt, M, Bishop, C, Bishop, K, Bishop, L, Bisnauthsing, K, Biswas, N, Biuk, S, Blachford, K, Black, E, Black, H, Black, K, Black, M, Black, P, Black, S, Blackgrove, H, Blackledge, B, Blackler, J, Blackley, S, Blackman, H, Blackstock, C, Blair, C, Blakemore, F, Blamey, H, Bland, A, Blane, S, Blankley, S, Blaxill, P, Blaylock, K, Blazeby, J, Blencowe, N, Bloom, B, Bloomfield, J, Bloss, A, Blowers, A, Blows, S, Bloxham, H, Blundell, L, Blunsum, A, Blunt, M, Blunt, T, Blyth, I, Blyth, K, Blythe, A, Blythe, K, Boampoaa, M, Board, S, Bobie, B, Bobruk, K, Bodalia, P, Bodasing, N, Boden, M, Bodenham, T, Boehmer, G, Boffito, M, Bohanan, K, Bohmov, K, Bohnacker, N, Bokhandi, S, Bokhar, M, Bokhari, S, Bokobza, I, Boles, A, Bolger, C, Bond, C, Bond, H, Bond, S, Bond, T, Bone, A, Boniface, G, Bonney, L, Booker, L, Boot, S, Boothroyd, M, Borbone, J, Borman, N, Bosence, S, Bostock, K, Botting, N, Bottrill, F, Bouattia, H, Bough, L, Boughton, H, Boult, Z, Boumrah, T, Bourke, M, Bourke, S, Bourne, M, Bousfield, R, Boustred, L, Bowes, A, Bowker, T, Bowler, H, Bowman, S, Bowmer, R, Bowring, A, Bowyer, H, Boyd, A, Boyd, J, Boyd, L, Boyer, N, Boyle, N, Boyle, R, Boyles, L, Brace, L, Bracken, A, Bradder, J, Bradley, C, Bradley, P, Bradley-Potts, J, Bradshaw, L, Bradshaw, Z, Brady, C, Brady, R, Brady, S, Braga Sardo, P, Braganza, D, Braithwaite, M, Brammer, S, Branch, M, Brankin-Frisby, T, Brannigan, J, Brattan, S, Bray, F, Bray, N, Brazil, M, Brear, L, Brear, T, Brearey, S, Bremner, L, Bresges, X, Bressington, C, Bretland, G, Brewer, C, Bridgett, M, Bridgwood, G, Brigham, S, Bright, J, Brightling, C, Brigstock, T, Brimfield, L, Brinksman, P, Brinkworth, E, Brittain-Long, R, Britten, V, Britton, H, Broad, L, Broadhead, S, Broadhurst, R, Broadley, A, Broadway, M, Brockelsby, C, Brocken, M, Brockley, T, Brodsky, M, Brogan, F, Brohan, L, Brokke, F, Brolly, J, Bromley, D, Brooke-Ball, H, Brooker, V, Brooking, D, Brooks, A, Brooks, D, Brooks, J, Brooks, K, Brooks, N, Brooks, P, Brooks, R, Brooks, S, Broom, M, Broomhead, N, Broughton, N, Broughton, C, Brouns, M, Brown, A, Brown, C, Brown, E, Brown, H, Brown, J, Brown, L, Brown, N, Brown, P, Brown, S, Brown, T, Browne, B, Browne, C, Browne, D, Browne, M, Browne, N, Brownlee, S, Brraka, A, Bruce, M, Brunchi, A, Brunskill, N, Brunton, A, Brunton, M, Bryant, M, Bryden, E, Brzezicki, H, Buazon, A, Buchan, R, Buchanan, R, Buche, D, Buck, L, Buck, A, Buckland, M, Buckley, C, Buckley, L, Buckley, P, Buckley, S, Buckman, C, Budds, A, Bugg, G, Bujazia, R, Bukhari, M, Bukhari, S, Bulbulia, R, Bull, A, Bull, D, Bull, K, Bull, R, Bull, T, Bullock, E, Bullock, S, Bulteel, N, Bumunarachchi, K, Bungue-Tuble, R, Burbidge, O, Burchett, C, Burda, D, Burden, C, Burden, T, Burgess, M, Burgess, R, Burgess, S, Burhan, H, Burke, H, Burke, K, Burman, A, Burnard, S, Burnett, C, Burnett, S, Burns, A, Burns, C, Burns, J, Burns, K, Burrage, D, Burrows, K, Burston, C, Burton, A, Burton, B, Burton, F, Burton, H, Burton, M, Butcher, D, Butler, A, Butler, E, Butler, J, Butler, P, Butler, S, Butt, A, Butt, M, Butterworth, C, Butterworth-Cowin, N, Buttery, R, Buttle, T, Button, H, Buttress, D, Bye, H, Byrne, J, Byrne, W, C Ooi, H, Cabandugama, A, Cabrero, L, Caddy, S, Cade, R, Cadwgan, A, Cahilog, Z, Cairney, D, Calderwood, J, Caldow, D, Cale, E, Calisti, G, Callaghan, D, Callaghan, J, Callum, D, Calver, C, Cambell-Kelly, M, Camburn, T, Cameron, D, Cameron, E, Cameron, F, Camm, C, Cammack, R, Campbell, A, Campbell, B, Campbell, J, Campbell, K, Campbell, R, Campbell, W, Campbell Hewson, Q, Camsooksai, J, Canclini, L, Candido, S, Candlish, J, Caneja, C, Cann, A, Cann, J, Cannan, R, Cannon, A, Cannon, E, Cannon, M, Cannon, P, Cannons, V, Canonizado, E, Cantliff, J, Caplin, B, Capocci, S, Caponi, N, Capp, A, Capstick, R, Capstick, T, Caraenache, C, Card, A, Cardwell, M, Carey, C, Carey, R, Carley, S, Carlin, F, Carlin, T, Carmichael, S, Carmody, 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Zulaikha, R, Zulfikar, S, Zullo, C, and Zuriaga-Alvaro, A
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- 2024
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41. Covalent adaptable networks and thermosets of multi-block ethylene/1-octene copolymers made by free-radical processing: Effects of melt flow index and crystallinity on thermomechanical properties and reprocessability
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Fenimore, Logan M., Chen, Boran, Chen, Yixuan, Barbon, Stephanie M., Brown, Hayley A., Auyeung, Evelyn, Shan, Colin Li Pi, and Torkelson, John M.
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- 2024
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42. Insights into the phototautomerism of free-base 5, 10, 15, 20-tetrakis(4-sulfonatophenyl) porphyrin
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Ciuti, Susanna, Carella, Angelo, Lucotti, Andrea, Tommasini, Matteo, Barbon, Antonio, and Di Valentin, Marilena
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- 2023
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43. Development of a dual hybrid AAV vector for endothelial-targeted expression of von Willebrand factor
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Barbon, Elena, Kawecki, Charlotte, Marmier, Solenne, Sakkal, Aboud, Collaud, Fanny, Charles, Severine, Ronzitti, Giuseppe, Casari, Caterina, Christophe, Olivier D., Denis, Cécile V., Lenting, Peter J., and Mingozzi, Federico
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- 2023
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44. Generation of human induced pluripotent stem cell lines derived from three Noonan syndrome patients from a single family carrying the heterozygous PTPN11 c.188 A > G (p.Y63C) mutation
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Giulia Sbrini, Zaira Tomasoni, Maria Rosa Cutrì, Alba Pilotta, Chiara Mingotti, Raffaele Badolato, Luca La Via, Alessandro Barbon, Federica Bono, and Chiara Fiorentini
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Biology (General) ,QH301-705.5 - Abstract
We have established Noonan syndrome (NS)-derived induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) of a family cohort carrying the heterozygous PTPN11 c.188 A > G (p.Y63C) mutation. The new iPSC lines were validated by confirming the normal karyotype and targeted mutation, the pluripotent gene expression, and the differentiation capacity into three germ layers.
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- 2024
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45. First-in-human Use of a Microsurgical Robotic System for Central Lymphatic Reconstruction
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Lisanne Grünherz, MD, Andrea Weinzierl, MD, Gilbert Dominique Puippe, MD, Donata von Reibnitz, MD, Carlotta Barbon, MD, Marcel André Schneider, MD, Pietro Giovanoli, MD, Christian Alexander Gutschow, MD, and Nicole Lindenblatt, MD
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Surgery ,RD1-811 - Abstract
Summary:. Advances in the development of robotic systems have recently enabled the use of robotic technology in reconstructive lymphatic surgery. Although the advantages of microsurgical robots must be weighed carefully against the costs, their use may allow for smaller surgical approaches and easier access to anatomically deeper structures or even smaller vessels. We report on a case of a patient with central lymphatic dilation causing abdominal pain and severely reduced physical capacity. Sonography-assisted intranodal injection of indocyanine green allowed for localization of the lymphatic cyst and anastomosis with the left ovarian vein, applying robotic-assisted microsurgery for the first time on the central lymphatic system. Following the successful reconstruction of lymphatic drainage and decompression of the cyst, the patient reported a complete regression of her preoperative symptoms. From a surgical point of view, the Symani Surgical System improved precision and allowed significantly smaller surgical access. Considering the high morbidity and rarity of pathologies of the central lymphatic system, central lymphatic surgery is to date rarely performed. With improved precision and significantly smaller surgical access, robotic-assisted microsurgery has great potential to expand the treatment options for central lymphatic lesions.
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- 2023
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46. Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
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Abani, O, Abbas, A, Abbas, F, Abbas, J, Abbas, K, Abbas, M, Abbasi, S, Abbass, H, Abbott, A, Abdallah, N, Abdelaziz, A, Abdelfattah, M, Abdelqader, B, Abdul, A, Abdul, B, Abdul, S, Abdul Rasheed, A, Abdulakeem, A, Abdul-Kadir, R, Abdullah, A, Abdulmumeen, A, Abdul-Raheem, R, Abdulshukkoor, N, Abdusamad, K, Abed El Khaleq, Y, Abedalla, M, Abeer Ul Amna, A, Abel, L, Abernethy, K, Abeywickrema, M, Abhinaya, C, Abidin, A, Aboaba, A, Aboagye-Odei, A, Aboah, C, Aboelela, H, Abo-Leyah, H, Abouelela, K, Abou-Haggar, A, Abouibrahim, M, Abousamra, A, Abouzaid, M, Abraham, M, Abraham, T, Abraheem, A, Abrams, J, Abrams, R, Abu, HJ, Abu-Arafeh, A, Abubacker, SM, Abung, A, Abusamra, Y, Aceampong, Y, Achara, A, Acharya, D, Acheampong, F, Acheampong, P, Acheampong, S, Acheson, J, Achieng, S, Acosta, A, Acquah, R, Acton, C, Adabie-Ankrah, J, Adair, P, Adam, AS, Adam, F, Adam, M, Adamali, H, Adamczyk, M, Adams, C, Adams, D, Adams, K, Adams, L, Adams, N, Adams, R, Adams, T, Adamu-Ikeme, L, Adatia, K, Adcock, K, Addai-Boampong, L, Addo, A, Adeagbo, O, Adebiyi, A, Adedeji, O, Adegeye, Y, Adegoke, K, Adell, V, Adenwalla, S, Adeoye, FW, Adesemoye, OA, Adewunmi, EO, Adeyanju, A, Adeyemi, J, Adeyemo, T, Adhikari, B, Adhikari, SA, Adhikary, R, Aditya, A, Adjepong, P, Adkins, G, Adnan, A, Adriaanse, M, Aeron-Thomas, J, Affleck, D, Afnan, C, Afridi, M, Afrim, P, Afriyie, FA, Aftab, ZA, Afum-Adjei Awuah, A, Agarwal, M, Agasiya, PN, Agbeko, R, Agbo, C, Aggarwal, S, Aghababaie, A, Aguilar Jimenez, L, Agyekum, JA, Agyen, K, Ahadome, EK, Ahamed Sadiq, S, Ahammed Nazeer, MH, Ahmad, M, Ahmad, S, Ahmed, A, Ahmed, BAR, Ahmed, B, Ahmed, F, Ahmed, H, Ahmed, I, Ahmed, K, Ahmed, L, Ahmed, M, Ahmed, MC, Ahmed, MS, Ahmed, N, Ahmed, O, Ahmed, RA, Ahmed, R, Ahmed, S, Ahmed, SG, Ahmed, SH, Ahmed Ali, R, Ahmed Mohamud, B, Ahmer, S, Ahonia, A, Aidoo, C, Aiken, C, Ail, D, Ainsworth, M, Aissa, M, Aitken, L, Ajay, B, Ajibode, A, Ajmi, A, Akhtar, N, Akili, S, Akinbiyi, B, Akindolie, O, Akinfenwa, Y, Akinkugbe, O, Akinpelu, I, Akram, M, Aktinade, O, Akudi, U, Al Aaraj, ASAR, Al Balushi, A, Al Dakhola, M, Al Swaifi, A, Al-Abadi, E, Alabi, A, Aladangady, N, Alafifi, M, Alam, A, Alam, S, Al-Asadi, A, Alatzoglou, K, Albert, P, Albertus, A, Albon, L, Alcala, A, Alcorn, G, Alcorn, S, Aldana, A, Alderdice, D, Aldesouki, A, Aldouri, R, Aldridge, J, Aldridge, N, Ale, RM, Alegria, A, Alexander, A, Alexander, C, Alexander, J, Alexander, PDG, Al-fori, J, Alghazawi, L, Alhabsha, O, Al-Hakim, B, Alhameed, R, Al-Hayali, M, Al-Hity, S, Ali, A, Ali, FR, Ali, J, Ali, M, Ali, MS, Ali, N, Ali, O, Ali, R, Ali, S, Aliberti, E, Alin, J, Alina, A, Alipustain, A, Alisjahbana, B, Aliyuda, F, Alizadeh, K, Al-Jibury, M, Al-Juboori, S, Al-Khalil, M, Alkhudhayri, A, Alkhusheh, M, Allan, F, Allan, N, Allanson, A, Allcock, R, Allen, E, Allen, J, Allen, K, Allen, L, Allen, P, Allen, R, Allen, S, Allen, T, Alli, A, Allison, K, Allman, B, Allsop, HK, Allsop, L, Allsup, D, Almahroos, AFT, Al-Moasseb, H, Al-Obaidi, M, Alomari, L, Al-Rabahi, A, Al-Ramadhani, B, Al-Saadi, Z, Al-Sammarraie, R, Alshaer, I, Al-Shahi Salman, R, Al-Shamkhani, W, Alsheikh, F, Al-Sheklly, B, Altaf, S, Alty, A, Alvarez, M, Alvarez Corral, M, Alveyn, E, Alzetani, M, Amamou, S, Amar, N, Ambalavanan, S, Ambrogetti, R, Ambrose, C, Ameen, A, Amelia Ganefianty, A, Ames, K, Amezaga, MR, Amin, A, Amin, K, Amin, S, Amin, T, Amit, B, Amjad, A, Amjad, N, Amoah-Dankwa, J, Amoako-Adusei, A, Amosun, V, Amsal, M, Amsha, K, Amuasi, J, Amutio Martin, N, Amy, P, Anada, A, Anand, A, Anandappa, S, Anantapatnaikuni, SD, Andari, NKN, Anderson, E, Anderson, J, Anderson, L, Anderson, M, Anderson, N, Anderson, R, Anderson, S, Anderson, W, Andreou, P, Andrews, A, Andrews, J, Aneke, K, Ang, A, Ang, WW, Angel, T, Angela, A, Angelini, P, Anguvaa, L, Anichtchik, O, Anim-Somuah, M, Aniruddhan, K, Annett, J, Anning, L, Ansah, M, Anstey, PJ, Anstey, R, Anthony, A, Anthony-Pillai, A, Antill, P, Antonina, Z, Anu, V, Anwar, M, Anwar, S, Apetri, E, Apostolopoulos, A, 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- 2023
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47. Trace encoding in process mining: A survey and benchmarking
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Tavares, Gabriel M., Oyamada, Rafael S., Barbon, Sylvio, Junior, and Ceravolo, Paolo
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- 2023
- Full Text
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48. Experimental and numerical investigation of the influence of terrain slope on the performance of single-axis trackers
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Barbón, A., Fortuny Ayuso, P., Bayón, L., and Silva, C.A.
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- 2023
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49. Development and preclinical evaluation of bioactive nerve conduits for peripheral nerve regeneration: A comparative study
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Stocco, Elena, Barbon, Silvia, Faccio, Diego, Petrelli, Lucia, Incendi, Damiana, Zamuner, Annj, De Rose, Enrico, Confalonieri, Marta, Tolomei, Francesco, Todros, Silvia, Tiengo, Cesare, Macchi, Veronica, Dettin, Monica, De Caro, Raffaele, and Porzionato, Andrea
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- 2023
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50. Continuous-wave and pulsed EPR studies of glass-like carbon with high spin concentration: Evidence for triplet states
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Fedaruk, Ryhor, Strzelczyk, Roman, Rusetsky, Grigory A., Barbon, Antonio, Majchrzycki, Łukasz, and Augustyniak-Jabłokow, Maria A.
- Published
- 2023
- Full Text
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