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1. Outcomes of mechanical thrombectomy for medium vessel occlusion in acute ischemic stroke patients with ASPECTS 4–5 vs. 6–7: a retrospective, multicenter, and multinational study

Author

Musmar, Basel, Salim, Hamza Adel, Adeeb, Nimer, Yedavalli, Vivek, Lakhani, Dhairya, El Naamani, Kareem, Henninger, Nils, Sundararajan, Sri Hari, Kühn, Anna Luisa, Khalife, Jane, Ghozy, Sherief, Scarcia, Luca, Tan, Benjamin Y. Q., Regenhardt, Robert W., Heit, Jeremy J., Cancelliere, Nicole M., Bernstock, Joshua D., Rouchaud, Aymeric, Fiehler, Jens, Sheth, Sunil, Puri, Ajit S., Dyzmann, Christian, Colasurdo, Marco, Barreau, Xavier, Renieri, Leonardo, Filipe, João Pedro, Harker, Pablo, Radu, Răzvan Alexandru, Abdalkader, Mohamad, Klein, Piers, Marotta, Thomas R., Spears, Julian, Ota, Takahiro, Mowla, Ashkan, Jabbour, Pascal, Biswas, Arundhati, Clarençon, Frédéric, Siegler, James E., Nguyen, Thanh N., Varela, Ricardo, Baker, Amanda, Essibayi, Muhammed Amir, Altschul, David, Gonzalez, Nestor R., Möhlenbruch, Markus A., Costalat, Vincent, Gory, Benjamin, Stracke, Christian Paul, Aziz-Sultan, Mohammad Ali, Hecker, Constantin, Shaikh, Hamza, Liebeskind, David S., Pedicelli, Alessandro, Alexandre, Andrea M., Tancredi, Illario, Faizy, Tobias D., Kalsoum, Erwah, Lubicz, Boris, Patel, Aman B., Pereira, Vitor Mendes, Guenego, Adrien, and Dmytriw, Adam A.

Published
2025
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2. Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Author

Dmytriw, Adam A., Salim, Hamza, Musmar, Basel, Aslan, Assala, Cancelliere, Nicole M., McLellan, Rachel M., Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, Naamani, Kareem El, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad U., Catapano, Joshua, Waqas, Muhammad, Tutino, Vincent M., Ibrahim, Mohamed K., Mohammed, Marwa A., Imamoglu, Cetin, Bayrak, Ahmet, Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer E., Ogilvie, Mark, Sporns, Peter, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie T., Psychogios, Marios, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan-Karl, Huynh, Thien, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed Amir, Sheth, Sunil A., Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph J., Asadi, Hamed, Siddiqui, Adnan, Brook, Allan L., Altschul, David, Ducruet, Andrew F., Albuquerque, Felipe C., Regenhardt, Robert W., Stapleton, Christopher J., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Tjoumakaris, Stavropoula I., Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo H., Jabbour, Pascal M., Pereira, Vitor Mendes, Patel, Aman B., and Adeeb, Nimer

Published
2024
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3. Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study

Author

El Naamani, Kareem, Mastorakos, Panagiotis, Adeeb, Nimer, Lan, Mathews, Castiglione, James, Khanna, Omaditya, Diestro, Jose Danilo Bengzon, McLellan, Rachel M., Dibas, Mahmoud, Vranic, Justin E., Aslan, Assala, Cuellar-Saenz, Hugo H., Guenego, Adrien, Carnevale, Joseph, Saliou, Guillaume, Ulfert, Christian, Möhlenbruch, Markus, Foreman, Paul M., Vachhani, Jay A., Hafeez, Muhammad U., Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Michelozzi, Caterina, Spears, Julian, Panni, Pietro, Griessenauer, Christoph J., Asadi, Hamed, Regenhardt, Robert W., Stapleton, Christopher J., Ghozy, Sherief, Siddiqui, Adnan, Patel, Nirav J., Kan, Peter, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Zanaty, Mario, Ghosh, Ritam, Abbas, Rawad, Amllay, Abdelaziz, Tjoumakaris, Stavropoula I., Gooch, Michael R., Cancelliere, Nicole M., Herial, Nabeel A., Rosenwasser, Robert H., Zarzour, Hekmat, Schmidt, Richard F., Pereira, Vitor Mendes, Patel, Aman B., Jabbour, Pascal, and Dmytriw, Adam A.

Published
2024
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4. Off-Label use of Woven EndoBridge device for intracranial brain aneurysm treatment: Modeling of occlusion outcome

Author

Dibas, Mahmoud, Spears, Julian, Sundararajan, Sri Hari, Al Balush, Ali, Vranic, Justin E., Inoue, Yasuaki, Mirshahi, Shervin, Alotaibi, Naif M., Harker, Pablo, Tutino, Vincent M., Sporns, Peter, Brehm, Alex, Essibayi, Muhammed Amir, Jabal, Mohamed Sobhi, Musmar, Basel, Adeeb, Nimer, Salim, Hamza, Aslan, Assala, Cancelliere, Nicole M., McLellan, Rachel M., Algin, Oktay, Ghozy, Sherief, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, Naamani, Kareem El, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M, Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad U., Catapano, Joshua, Waqas, Muhammad, Yavuz, Kivilcim, Gunes, Yasin Celal, Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Starke, Robert M., Hassan, Ameer, Ogilvie, Mark, Nguyen, Anh, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie T., Psychogios, Marios, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan-Karl, Huynh, Thien, Gutierrez, Juan Carlos Martinez, Sheth, Sunil A., Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph J., Asadi, Hamed, Siddiqui, Adnan, Brook, Allan L., Haranhalli, Neil, Ducruet, Andrew F., Albuquerque, Felipe C., Regenhardt, Robert W., Stapleton, Christopher J., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Tjoumakaris, Stavropoula I., Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo H., Jabbour, Pascal M, Pereira, Vitor Mendes, Patel, Aman B., Altschul, David, and Dmytriw, Adam A.

Published
2024
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7. The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Knopman, Jared, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
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8. Correction to: The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Jared Knopman, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
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10. Improved Generalizability in Medical Computer Vision: Hyperbolic Deep Learning in Multi-Modality Neuroimaging.

Author

Ayubcha, Cyrus, Sajed, Sulaiman, Omara, Chady, Veldman, Anna B., Singh, Shashi B., Lokesha, Yashas Ullas, Liu, Alex, Aziz-Sultan, Mohammad Ali, Smith, Timothy R., and Beam, Andrew

Subjects
COMPUTER-assisted image analysis (Medicine), CONVOLUTIONAL neural networks, COMPUTER vision, HYPERBOLOID structures, ALZHEIMER'S disease, DEEP learning
Abstract

Deep learning has shown significant value in automating radiological diagnostics but can be limited by a lack of generalizability to external datasets. Leveraging the geometric principles of non-Euclidean space, certain geometric deep learning approaches may offer an alternative means of improving model generalizability. This study investigates the potential advantages of hyperbolic convolutional neural networks (HCNNs) over traditional convolutional neural networks (CNNs) in neuroimaging tasks. We conducted a comparative analysis of HCNNs and CNNs across various medical imaging modalities and diseases, with a focus on a compiled multi-modality neuroimaging dataset. The models were assessed for their performance parity, robustness to adversarial attacks, semantic organization of embedding spaces, and generalizability. Zero-shot evaluations were also performed with ischemic stroke non-contrast CT images. HCNNs matched CNNs' performance in less complex settings and demonstrated superior semantic organization and robustness to adversarial attacks. While HCNNs equaled CNNs in out-of-sample datasets identifying Alzheimer's disease, in zero-shot evaluations, HCNNs outperformed CNNs and radiologists. HCNNs deliver enhanced robustness and organization in neuroimaging data. This likely underlies why, while HCNNs perform similarly to CNNs with respect to in-sample tasks, they confer improved generalizability. Nevertheless, HCNNs encounter efficiency and performance challenges with larger, complex datasets. These limitations underline the need for further optimization of HCNN architectures. HCNNs present promising improvements in generalizability and resilience for medical imaging applications, particularly in neuroimaging. Despite facing challenges with larger datasets, HCNNs enhance performance under adversarial conditions and offer better semantic organization, suggesting valuable potential in generalizable deep learning models in medical imaging and neuroimaging diagnostics. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Somatic Variants in SVIL in Cerebral Aneurysms

Author

Lai, Pui Man Rosalind, Ryu, Jee-Yeon, Park, Sang-Cheol, Gross, Bradley A., Dickinson, Lawrence D., Dagen, Sarajune, Aziz-Sultan, Mohammad Ali, Boulos, Alan S., Barrow, Daniel L., Batjer, H. Hunt, Blackburn, Spiros, Chang, Edward F., Chen, P. Roc, Colby, Geoffrey P., Cosgrove, Garth Rees, David, Carlos A., Day, Arthur L., Frerichs, Kai U., Niemela, Mika, Ojemann, Steven G., Patel, Nirav J., Shi, Xiangen, Valle-Giler, Edison P., Wang, Anthony C., Welch, Babu G., Zusman, Edie E., Weiss, Scott T., and Du, Rose

Published
2022
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15. International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Diestro, Jose Danilo Bengzon, Dibas, Mahmoud, Phan, Kevin, Sweid, Ahmad, Cuellar-Saenz, Hugo H., Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Sundararajan, Sri Hari, Carnevale, Joseph, Saliou, Guillaume, Möhlenbruch, Markus, Vranic, Justin E., Rabinov, James D., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Abbas, Rawad, Inoue, Yasuaki, Capirossi, Carolina, Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna Luisa, Michelozzi, Caterina, Elens, Stéphanie, Regenhardt, Robert W., Ghozy, Sherief, Alotaibi, Naif M., Tjoumakaris, Stavropoula, Starke, Robert M., Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Brooks, Mark, Maingard, Julian, Jhamb, Ashu, Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Savardekar, Amey, Boddu, Srikanth, Knopman, Jared, Limbucci, Nicola, Chen, Karen S., Aziz-Sultan, Mohammad A., Stapleton, Christopher J., Jabbour, Pascal, Cognard, Christophe, Patel, Aman B., and Adeeb, Nimer

Published
2021
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20. Endovascular Applications for the Management of High-Grade Gliomas in the Modern Era.

Author

Kappel, Ari D., Jha, Rohan, Guggilapu, Saibaba, Smith, William J., Feroze, Abdullah H., Dmytriw, Adam A., Vicenty-Padilla, Juan, Alcedo Guardia, Rodolfo E., Gessler, Florian A., Patel, Nirav J., Du, Rose, See, Alfred P., Peruzzi, Pier Paolo, Aziz-Sultan, Mohammad A., and Bernstock, Joshua D.

Subjects
GLIOMA treatment, PATIENT safety, BLOOD-brain barrier, ENDOVASCULAR surgery, TUMOR grading, MINIMALLY invasive procedures, DRUG delivery systems, ULTRASONIC imaging, CANCER chemotherapy
Abstract

Simple Summary: This review discusses new treatments for high-grade gliomas (HGGs), aggressive brain tumors that are difficult to treat. It focuses on emerging endovascular therapies and future directions. Endovascular methods use catheters in a minimally invasive manner to deliver drugs to the tumor through blood vessels in the brain while limiting harm to the rest of the body. Super-selective intra-arterial cerebral infusion (SSIACI) is an endovascular technique that aims to deliver treatments directly to the tumor by reaching the closest blood vessels supplying the tumor. Many challenges remain to fully adopting these techniques in clinical practice, including the ability of drugs to cross the blood–brain barrier, and getting the drugs to stay in the tumor for long enough before they are washed out by normal blood in the brain. Focused ultrasound and hyperosmotic disruption are techniques which might help with these challenges. Researchers are investigating new drugs beyond traditional chemotherapies, such as radiation embedded molecules and immune-based therapies. Future directions include monitoring tumors with endovascular sampling; changing drug formulations to stay in the tumor longer; and investigating other treatments, like radioembolization. These endovascular strategies have the potential to improve how HGGs are treated, but more research is needed to ensure they work well and are safe for patients. High-grade gliomas (HGGs) have a poor prognosis and are difficult to treat. This review examines the evolving landscape of endovascular therapies for HGGs. Recent advances in endovascular catheter technology and delivery methods allow for super-selective intra-arterial cerebral infusion (SSIACI) with increasing precision. This treatment modality may offer the ability to deliver anti-tumoral therapies directly to tumor regions while minimizing systemic toxicity. However, challenges persist, including blood–brain barrier (BBB) penetration, hemodynamic complexities, and drug–tumor residence time. Innovative adjunct techniques, such as focused ultrasound (FUS) and hyperosmotic disruption, may facilitate BBB disruption and enhance drug penetration. However, hemodynamic factors that limit drug residence time remain a limitation. Expanding therapeutic options beyond chemotherapy, including radiotherapy and immunobiologics, may motivate future investigations. While preclinical and clinical studies demonstrate moderate efficacy, larger randomized trials are needed to validate the clinical benefits. Additionally, future directions may involve endovascular sampling for peri-tumoral surveillance; changes in drug formulations to prolong residence time; and the exploration of non-pharmaceutical therapies, like radioembolization and photodynamic therapy. Endovascular strategies hold immense potential in reshaping HGG treatment paradigms, offering targeted and minimally invasive approaches. However, overcoming technical challenges and validating clinical efficacy remain paramount for translating these advancements into clinical care. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Impact of Balloon Guide Catheter Use on Clinical and Angiographic Outcomes in the STRATIS Stroke Thrombectomy Registry

Author

Zaidat, Osama O., Mueller-Kronast, Nils H., Hassan, Ameer E., Haussen, Diogo C., Jadhav, Ashutosh P., Froehler, Michael T., Jahan, Reza, Ali Aziz-Sultan, Mohammad, Klucznik, Richard P., Saver, Jeffrey L., Hellinger, Frank R., Jr, Yavagal, Dileep R., Yao, Tom L., Gupta, Rishi, Martin, Coleman O., Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G., Gandhi, Ravi H., Peterson, Eric C., Dashti, Shervin, Given, Curtis A., II, Mehta, Brijesh P., Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H., Kvamme, Peter, Grobelny, Thomas J., Hussain, Muhammad Shazam, Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J., Ecker, Robert D., Schirmer, Clemens M., Sauvageau, Eric, Chebl, Alex Bou, Derdeyn, Colin P., Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H., Dumont, Travis M., Alhajeri, Abdulnasser, Taqi, Muhammad A., Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S., Chitale, Rohan, Deshaies, Eric M., Robinson, David, Kallmes, David F., Baxter, Blaise W., Jumaa, Mouhammed, Sunenshine, Peter, Majjhoo, Aniel, English, Joey D., Suzuki, Shuichi, Fessler, Richard D., Delgado-Almandoz, Josser, Martin, Jerry C., and Liebeskind, David S.

Published
2019
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24. Safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide necked bifurcation aneurysms: final 5 year results of the pivotal WEB Intra-saccular Therapy study (WEB-IT).

Author

Fiorella, David, Molyneux, Andy, Coon, Alex, Szikora, Istvan, Saatci, Isil, Baltacioglu, Feyyaz, Aziz-Sultan, Mohammad A., Hoit, Daniel, Delgado Almandoz, Josser E., Elijovich, Lucas, Cekirge, H. Saruhan, Byrne, James, Klisch, Joachim, and Arthur, Adam S.

Subjects
PATIENT aftercare, CLINICAL trials, THERAPEUTIC embolization, TREATMENT effectiveness, DIAGNOSTIC imaging, REOPERATION, DESCRIPTIVE statistics, RESEARCH funding, ADVERSE health care events, PATIENT safety, INTRACRANIAL aneurysms, LONGITUDINAL method, EVALUATION
Abstract

Introduction The US Woven EndoBridge Intra-saccular Therapy (WEB-IT) study is a pivotal, prospective, single arm, investigational device exemption study to evaluate the safety and effectiveness of the WEB device for the treatment of wide neck bifurcation aneurysms (WNBAs). We present complete 5 year data for the cohort of 150 patients. Methods 150 patients with WNBAs were enrolled at 21 US and six international centers. Imaging from the index procedure, 6 month, 1 year, 3 year, and 5 year follow-up were reviewed by a core laboratory. Adverse events were reviewed and adjudicated by a clinical events adjudicator. Results 83 patients had 5 year follow-up imaging and 123 had clinical follow-up. No ruptured (0/9) or unruptured aneurysm (0/141) rebled or bled during follow-up. No new device or procedure related adverse events or serious adverse events were reported after 1 year. At 5 years, using the LOCF method, complete occlusion was observed in 58.1% and adequate occlusion in 87.2% of patients. For patients with both 1 year and 5 year occlusion statuses available, 76.8% (63/82) of aneurysms remained stable or improved with no retreatment. After 1 year, 18 aneurysms were retreated, 11 of which were adequately occluded at 1 year, and 15 of which were retreated in the absence of any deterioration in occlusion grade. Conclusions Five year follow-up data from the WEB-IT study demonstrated that the WEB device was safe and effective when used in the treatment of WNBAs. Aneurysm occlusion rates achieved at 1 year follow-up were durable, with rates of progressive thrombosis far exceeding rates of recurrence over time. [ABSTRACT FROM AUTHOR]

Published
2023
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29. Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke)

Author

Froehler, Michael T., Saver, Jeffrey L., Zaidat, Osama O., Jahan, Reza, Aziz-Sultan, Mohammad Ali, Klucznik, Richard P., Haussen, Diogo C., Hellinger, Frank R., Jr., Yavagal, Dileep R., Yao, Tom L., Liebeskind, David S., Jadhav, Ashutosh P., Gupta, Rishi, Hassan, Ameer E., Martin, Coleman O., Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G., Gandhi, Ravi H., Peterson, Eric C., Dashti, Shervin R., Given, Curtis A., II, Mehta, Brijesh P., Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H., Kvamme, Peter, Grobelny, Thomas J., Hussain, Muhammad S., Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J., Ecker, Robert D., Schirmer, Clemens M., Sauvageau, Eric, Abou-Chebl, Alex, Derdeyn, Colin P., Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H., Dumont, Travis M., Alhajeri, Abdulnasser, Taqi, M. Asif, Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S., Chitale, Rohan, Deshaies, Eric M., Robinson, David H., Kallmes, David F., Baxter, Blaise W., Jumaa, Mouhammad A., Sunenshine, Peter, Majjhoo, Aniel, English, Joey D., Suzuki, Shuichi, Fessler, Richard D., Delgado Almandoz, Josser E., Martin, Jerry C., and Mueller-Kronast, Nils H.

Published
2017
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30. Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke: Primary Results of the STRATIS Registry

Author

Mueller-Kronast, Nils H., Zaidat, Osama O., Froehler, Michael T., Jahan, Reza, Aziz-Sultan, Mohammad Ali, Klucznik, Richard P., Saver, Jeffrey L., Hellinger, Frank R., Jr, Yavagal, Dileep R., Yao, Tom L., Liebeskind, David S., Jadhav, Ashutosh P., Gupta, Rishi, Hassan, Ameer E., Martin, Coleman O., Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G., Gandhi, Ravi H., Peterson, Eric C., Dashti, Shervin R., Given, Curtis A., II, Mehta, Brijesh P., Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H., Kvamme, Peter, Grobelny, Thomas J., Hussain, Muhammad S., Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J., Ecker, Robert D., Schirmer, Clemens M., Sauvageau, Eric, Abou-Chebl, Alex, Derdeyn, Colin P., Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H., Dumont, Travis M., Alhajeri, Abdulnasser, Taqi, M. Asif, Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S., Chitale, Rohan, Deshaies, Eric M., Robinson, David H., Kallmes, David F., Baxter, Blaise W., Jumaa, Mouhammad A., Sunenshine, Peter, Majjhoo, Aniel, English, Joey D., Suzuki, Shuichi, Fessler, Richard D., Delgado Almandoz, Josser E., Martin, Jerry C., and Haussen, Diogo C.

Published
2017
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32. Contributors

Author

Ahmed, S. Uzair, Albuquerque, Felipe C., Amar, Arun Paul, Amllay, Abdelaziz, Antonios, Joseph P., Apuzzo, Michael L.J., Atalay, Yahya B., Ayub, Muhammad Abubakar, Aziz-Sultan, Mohammad A., Barros, Guilherme, Barrow, Daniel L., Bernardo, Antonio, Boddu, Srikanth, Bolar, Divya S., Caplan, Justin M., Carnevale, Joseph A., Carroll, Kate T., Catapano, Joshua S., Chen, Ching-Jen, Sander Connolly, E., Jr., David, Carlos A., Desai, Milli J., Dodd, William, Dornbos, David, III, Dowd, Richard S., Faramand, Andrew, Fejleh, Ashley, Flickinger, John C., Fraser, Justin F., Friedlander, Robert M., Garton, Andrew L.A., Ghannam, Moleca, Giantini-Larsen, Alexandra M., Goldberg, Jacob L., Goutnik, Michael, Gross, Bradley A., Hardigan, Trevor, Hoh, Brian L., Howard, Brian M., Hsiao, Albert, Huang, Judy, Jackson, Christopher M., Kano, Hideyuki, Karanjia, Navaz, Khalessi, Alexander A., Kim, Jennifer E., Kim, Louis J., Knopman, Jared, Kocharian, Gary, Lai, Pui Man Rosalind, Lam, Arthur M., Lamorie-Foote, Krista, Lang, Michael J., Laurent, Dimitri, Lawton, Michael T., Lee, Hubert, Lemkuil, Brian P., Levy, Elad I., Lucke-Wold, Brandon, Lunsford, L. Dade, Mack, William, Matouk, Charles C., McCarthy, David J., Meyer, R. Michael, Mocco, J, Mouchtouris, Nikolaos, Murthy, Santosh B., Niranjan, Ajay, Nistal, Dominic A., Norbash, Alexander, Ogilvy, Christopher S., Oh, S. Paul, Pannell, J. Scott, Patel, Aman B., Rahmani, Redi, Ramos, Alexander D., Regenhardt, Robert W., Renedo, Daniela, Rosenwasser, Robert H., Roytman, Michelle, Russin, Jonathan, Salem, Mohamed M., Scherschinski, Lea, Schwarz, Justin, Sekhar, Laligam N., Sen, Rajeev D., Sheehan, Jason P., Shenoy, Varadaraya S., Siddiqui, Adnan H., Sizdahkhani, Saman, Small, Coulter Nathan, Soman, Salil, Souweidane, Mark M., Spinazzi, Eleonora F., Srinivas, Shanmukha, Srinivasan, Visish M., Steinberg, Gary K., Stieg, Philip E., Sujijantarat, Nanthiya, Sweid, Ahmad, Tahir, Rizwan, Tamargo, Rafael J., Tjoumakaris, Stavropoula, Tsiouris, Apostolos John, Vranic, Justin E., Wali, Arvin R., Waqas, Muhammad, White, Halina, Xu, Risheng, Yachnis, Anthony T., Yaeger, Kurt, Yun, Jonathan J., and Zetchi, Akli

Published
2024
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44. Effects of the COVID-19 pandemic on stroke response times: a systematic review and meta-analysis.

Author

Nawabi, Noah L. A., Duey, Akiro H., Kilgallon, John L., Jessurun, Charissa, Doucette, Joanne, Mekary, Rania A., and Aziz-Sultan, Mohammad Ali

Subjects
STROKE treatment, ONLINE information services, MEDICAL databases, HOSPITAL emergency services, META-analysis, CONFIDENCE intervals, MEDICAL information storage & retrieval systems, TIME, SYSTEMATIC reviews, DESCRIPTIVE statistics, MEDLINE, COVID-19 pandemic
Abstract

Objectives COVID-19 presents a risk for delays to stroke treatment. We examined how COVID-19 affected stroke response times. Methods A literature search was conducted to identify articles covering stroke during COVID-19 that included time metrics data pre- and post-pandemic. For each outcome, pooled relative change from baseline and 95% CI were calculated using random-effects models. Heterogeneity was explored through subgroup analyses comparing comprehensive stroke centers (CSCs) to non-CSCs. Results 38 included studies reported on 6109 patients during COVID- 19 and 14 637 patients during the pre-COVID period. Pooled increases of 20.9% (95% CI 5.8% to 36.1%) in last-known-well (LKW) to arrival times, 1.2% (-2.9% to 5.3%) in door-to-imaging (DTI), 0.8% (-2.9% to 4.5%) in door-to-needle (DTN), 2.8% (-5.0% to 10.6%) in door-to-groin (DTG), and 19.7% (11.1% to 28.2%) in door-to-reperfusion (DTR) times were observed during COVID-19. At CSCs, LKW increased by 24.0% (-0.3% to 48.2%), DTI increased by 1.6% (-3.0% to 6.1%), DTN increased by 3.6% (1.2% to 6.0%), DTG increased by 4.6% (-5.9% to 15.1%), and DTR increased by 21.2% (12.3% to 30.1%). At non-CSCs, LKW increased by 12.4% (-1.0% to 25.7%), DTI increased by 0.2% (-2.0% to 2.4%), DTN decreased by -4.6% (-11.9% to 2.7%), DTG decreased by -0.6% (-8.3% to 7.1%), and DTR increased by 0.5% (-31.0% to 32.0%). The increases during COVID-19 in LKW (p=0.01) and DTR (p=0.00) were statistically significant, as was the difference in DTN delays between CSCs and non-CSCs (p=0.04). Conclusions Factors during COVID-19 resulted in significantly delayed LKW and DTR, and mild delays in DTI, DTN, and DTG. CSCs experience more pronounced delays than non-CSCs. [ABSTRACT FROM AUTHOR]

Published
2022
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48. Experience With the Pipeline Embolization Device for Posterior Circulations Aneurysms: A Multicenter Cohort Study.

Author

Griessenauer, Christoph J, Enriquez-Marulanda, Alejandro, Taussky, Philipp, Biswas, Arundhati, Grandhi, Ramesh, Xiang, Sissi, Hong, Tao, Rinaldo, Lorenzo, Lanzino, Giuseppe, Brinjikji, Waleed, Burkhardt, Jan-Karl, Kan, Peter, Ghuman, Mandeep, Yang, Victor X D, Chen, Karen, Aziz-Sultan, Mohammad A, Ghorbani, Mohammad, Schirmer, Clemens M, Goren, Oded, and Dalal, Shamsher S

Published
2020
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