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9. Analysis of the ionized interstellar medium and orbital dynamics of PSR J1909-3744 using scintillation arcs.

Author

Askew, J, Reardon, D J, and Shannon, R M

Subjects
*INTERSTELLAR medium, *RADIO telescopes, *ORBITS (Astronomy), *PULSARS, *POWER spectra, *BINARY pulsars
Abstract

Long-term studies of binary millisecond pulsars (MSPs) provide precise tests of strong-field gravity, and can be used to measure neutron-star masses. PSR J1909-3744, a binary MSP has been the subject of several pulsar timing analyses. The edge-on orbit enables measurement of its mass using the Shapiro delay; however, there is degeneracy in the sense of the inclination angle, i , and multiple solutions for the longitude of ascending node, Ω. Radio pulsars scintillate due to inhomogeneities in the ionized interstellar medium (IISM). This can result in scintillation arcs in the power spectrum of the dynamic spectrum that can use these to study the interstellar medium and constrain binary pulsar orbits. Here, we study the scintillation of PSR J1909-3744 using observations from the 64-m Parkes Radio Telescope (Murriyang) over ≈13 yr, using techniques to study scintillation in a lower signal-to-noise regime. By monitoring annual and orbital variations of the arc-curvature measurements, we are able to characterize the velocity of the IISM. We find that the statistics of the IISM remained stationary over this time and a slightly anisotropic model (axial ratio ≳1.2) is preferred. We measure the relative distance to a single dominant thin scattering screen at s  = 0.49 ± 0.04, or D s = 590 ± 50 pc, with an angle of anisotropy ζ = 85 ± 6° (East of North) and velocity in the direction of anisotropy V IISM,ζ = 14 ± 10 km s−1. By combining a physical model of the IISM and current pulsar timing results, we also constrain Ω = 225 ± 3° and i  = 86.46 ± 0.05°. [ABSTRACT FROM AUTHOR]

Published
2023
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11. Impact of COVID-19 on the imaging diagnosis of cardiac disease in Europe

Author

Williams M. C., Shaw L., Hirschfeld C. B., Maurovich-Horvat P., Norgaard B. L., Pontone G., Jimenez-Heffernan A., Sinitsyn V., Sergienko V., Ansheles A., Bax J. J., Buechel R., Milan E., Slart R. H. J. A., Nicol E., Bucciarelli-Ducci C., Pynda Y., Better N., Cerci R., Dorbala S., Raggi P., Villines T. C., Vitola J., Malkovskiy E., Goebel B., Cohen Y., Randazzo M., Pascual T. N. B., Dondi M., Paez D., Einstein A. J., Nasery M. N., Goda A., Shirka E., Benlabgaa R., Bouyoucef S., Medjahedi A., Nailli Q., Agolti M., Aguero R. N., Del Carmen Alak M., Alberguina L. G., Arronada G., Astesiano A., Norton C. B., Benteo P., Blanco J., Bonelli J. M., Bustos J. J., Cabrejas R., Cachero J., Campisi R., Canderoli A., Carames S., Carrascosa P., Castro R., Cendoya O., Cognigni L. M., Collaud C., Cortes C., Courtis J., Cragnolino D., Daicz M., De La Vega A., De Maria S. T., Del Riego H., Dettori F., Deviggiano A., Dragonetti L., Embon M., Enriquez R. E., Ensinas J., Faccio F., Facello A., Garofalo D., Geronazzo R., Gonza N., Gutierrez L., Guzzo M. A., Hasbani V., Huerin M., Jager V., Lewkowicz J. M., De Munain M. N. A. L., Lotti J. M., Marquez A., Masoli O., Masoli O. H., Mastrovito E., Mayoraz M., Melado G. E., Mele A., Merani M. F., Meretta A. H., Molteni S., Montecinos M., Noguera E., Novoa C., Sueldo C. P., Ascani S. P., Pollono P., Pujol M. P., Radzinschi A., Raimondi G., Redruello M., Rodriguez M., Romero R. L., Acuna A. R., Rovaletti F., Miguel L. S., Solari L., Strada B., Traverso S., Traverzo S. S., Del Huerto Velazquez Espeche M., Weihmuller J. S., Wolcan J., Zeffiro S., Sakanyan M., Beuzeville S., Boktor R., Butler P., Calcott J., Carr L., Chan V., Chao C., Chong W., Dobson M., Downie D., Dwivedi G., Elison B., Engela J., Francis R., Gaikwad A., Basavaraj A. G., Goodwin B., Greenough R., Hamilton-Craig C., Hsieh V., Joshi S., Lederer K., Lee K., Lee J., Magnussen J., Mai N., Mander G., Murton F., Nandurkar D., Neill J., O'Rourke E., O'Sullivan P., Pandos G., Pathmaraj K., Pitman A., Poulter R., Premaratne M., Prior D., Ridley L., Rutherford N., Salehi H., Saunders C., Scarlett L., Seneviratne S., Shetty D., Shrestha G., Shulman J., Solanki V., Stanton T., Stuart M., Stubbs M., Swainson I., Taubman K., Taylor A., Thomas P., Unger S., Upton A., Vamadevan S., Van Gaal W., Verjans J., Voutnis D., Wayne V., Wilson P., Wong D., Wong K., Younger J., Feuchtner G., Mirzaei S., Weiss K., Maroz-Vadalazhskaya N., Gheysens O., Homans F., Moreno-Reyes R., Pasquet A., Roelants V., Van De Heyning C. M., Rios R. A., Soldat-Stankovic V., Stankovic S., Siqueira M. H. A., Almeida A., Togni P. H. A., Andrade J. H., Andrade L., Anselmi C., Araujo R., Azevedo G., Bezerra S., Biancardi R., Grossman G. B., Brandao S., Pianta D. B., Carreira L., Castro B., Chang T., Cunali F., Cury R., Dantas R., De Amorim Fernandes F., De Lorenzo A., De MacEdo Filho R., Erthal F., Fernandes F., Fernandes J., De Souza T. F., Alves W. F., Ghini B., Goncalves L., Gottlieb I., Hadlich M., Kameoka V., Lima R., Lima A., Lopes R. W., E Silva R. M., Magalhaes T., Silva F. M., Mastrocola L. E., Medeiros F., Meneghetti J. C., Naue V., Naves D., Nolasco R., Nomura C., Oliveira J. B., Paixao E., De Carvalho F. P., Pinto I., Possetti P., Quinta M., Ramos R. R. N., Rocha R., Rodrigues A., Rodrigues C., Romantini L., Sanches A., Santana S., Da Silva L. S., Schvartzman P., Matushita C. S., Senra T., Shiozaki A., De Siqueira M. E. M., Siqueira C., Smanio P., Soares C. E., Soares J., Bittencourt M. S., Spiro B., Mesquita C. T., Torreao J., Torres R., Uellendahl M., Monte G. U., Verissimo O., Cabeda E. V., Pedras F. V., Waltrick R., Zapparoli M., Naseer H., Garcheva-Tsacheva M., Kostadinova I., Theng Y., Abikhzer G., Barette R., Chow B., Dabreo D., Friedrich M., Garg R., Hafez M. N., Johnson C., Kiess M., Leipsic J., Leung E., Miller R., Oikonomou A., Probst S., Roifman I., Small G., Tandon V., Trivedi A., White J., Zukotynski K., Canessa J., Munoz G. C., Concha C., Hidalgo P., Lovera C., Massardo T., Vargas L. S., Abad P., Arturo H., Ayala S., Benitez L., Cadena A., Caicedo C., Moncayo A. C., Gomez S., Villamil C. T. G., Jaimes C., Londono J., Blair J. L. L., Pabon L., Pineda M., Rojas J. C., Ruiz D., Escobar M. V., Vasquez A., Vergel D., Zuluaga A., Gamboa I. B., Castro G., Gonzalez U., Baric A., Batinic T., Franceschi M., Hrabak M., Jukic M., Medakovic P., Persic V., Prpic M., Punda A., Batista J. F., Lauchy J. M. G., Gutierrez Y. M., Menendez R., Peix A., Rochela L., Panagidis C., Petrou I., Engelmann V., Kaminek M., Kincl V., Lang O., Simanek M., Abdulla J., Bottcher M., Christensen M., Gormsen L. C., Hasbak P., Hess S., Holdgaard P., Johansen A., Kyhl K., Ovrehus K. A., Sand N. P. R., Steffensen R., Thomassen A., Zerahn B., Perez A., Velez G. A. E., Velez M. S., Aziz I. S. A., Abougabal M., Ahmed T., Allam A., Asfour A., Hassan M., Hassan A., Ibrahim A., Kaffas S., Kandeel A., Ali M. M., Mansy A., Maurice H., Nabil S., Shaaban M., Flores A. C., Poksi A., Knuuti J., Kokkonen V., Larikka M., Uusitalo V., Bailly M., Burg S., Deux J. -F., Habouzit V., Hyafil F., Lairez O., Proffit F., Regaieg H., Sarda-Mantel L., Tacher V., Schneider R. P., Ayetey H., Angelidis G., Archontaki A., Chatziioannou S., Datseris I., Fragkaki C., Georgoulias P., Koukouraki S., Koutelou M., Kyrozi E., Repasos E., Stavrou P., Valsamaki P., Gonzalez C., Gutierrez G., Maldonado A., Buga K., Garai I., Schmidt E., Szilveszter B., Varady E., Banthia N., Bhagat J. K., Bhargava R., Bhat V., Bhatia M., Choudhury P., Chowdekar V. S., Irodi A., Jain S., Joseph E., Kumar S., Mahapatra G., Mitra D., Mittal B. R., Ozair A., Patel C., Patel T., Patel R., Patel S., Saxena S., Sengupta S., Singh S., Singh B., Sood A., Verma A., Affandi E., Alam P. S., Edison E., Gunawan G., Hapkido H., Hidayat B., Huda A., Mukti A. P., Prawiro D., Soeriadi E. A., Syawaluddin H., Albadr A., Assadi M., Emami F., Houshmand G., Maleki M., Rostami M. T., Zakavi S. R., Zaid E. A., Agranovich S., Arnson Y., Bar-Shalom R., Frenkel A., Knafo G., Lugassi R., Moalem I. S. M., Mor M., Muskal N., Ranser S., Shalev A., Albano D., Alongi P., Arnone G., Bagatin E., Baldari S., Bauckneht M., Bertelli P., Bianco F., Bonfiglioli R., Boni R., Bruno A., Bruno I., Busnardo E., Califaretti E., Camoni L., Carnevale A., Casoni R., Cavallo A. U., Cavenaghi G., Chierichetti F., Chiocchi M., Cittanti C., Colletta M., Conti U., Cossu A., Cuocolo A., Cuzzocrea M., De Rimini M. L., De Vincentis G., Del Giudice E., Del Torto A., Della Tommasina V., Durmo R., Erba P. A., Evangelista L., Faletti R., Faragasso E., Farsad M., Ferro P., Florimonte L., Frantellizzi V., Fringuelli F. M., Gatti M., Gaudiano A., Gimelli A., Giubbini R., Giuffrida F., Ialuna S., Laudicella R., Leccisotti L., Leva L., Liga R., Liguori C., Longo G., Maffione M., Mancini M. E., Marcassa C., Nardi B., Pacella S., Pepe G., Pulizzi S., Quartuccio N., Rampin L., Ricci F., Rossini P., Rubini G., Russo V., Sacchetti G. M., Sambuceti G., Scarano M., Sciagra R., Sperandio M., Stefanelli A., Ventroni G., Zoboli S., Baugh D., Chambers D., Madu E., Nunura F., Asano H., Chimura C. M., Fujimoto S., Fujisue K., Fukunaga T., Fukushima Y., Fukuyama K., Hashimoto J., Ichikawa Y., Iguchi N., Imai M., Inaki A., Ishimura H., Isobe S., Kadokami T., Kato T., Kudo T., Kumita S., Maruno H., Mataki H., Miyagawa M., Morimoto R., Moroi M., Nagamachi S., Nakajima K., Nakata T., Nakazato R., Nanasato M., Naya M., Norikane T., Ohta Y., Okayama S., Okizaki A., Otomi Y., Otsuka H., Saito M., Sakata S. Y., Sarai M., Sato D., Shiraishi S., Suwa Y., Takanami K., Takehana K., Taki J., Tamaki N., Taniguchi Y., Teragawa H., Tomizawa N., Tsujita K., Umeji K., Wakabayashi Y., Yamada S., Yamazaki S., Yoneyama T., Rawashdeh M., Batyrkhanov D., Dautov T., Makhdomi K., Ombati K., Alkandari F., Garashi M., Coie T. L., Rajvong S., Kalinin A., Kalnina M., Haidar M., Komiagiene R., Kviecinskiene G., Mataciunas M., Vajauskas D., Picard C., Karim N. K. A., Reichmuth L., Samuel A., Allarakha M. A., Naojee A. S., Alexanderson-Rosas E., Barragan E., Becerril A., Gonzalez-Montecinos, Cabada M., Rodriguez D. C., Carvajal-Juarez I., Cortes V., Cortes F., De La Pena E., Gama-Moreno M., Gonzalez L., Ramirez N. G., Jimenez-Santos M., Matos L., Monroy E., Morelos M., Ornelas M., Ramirez J. A. O., Preciado-Anaya A., Preciado-Gutierrez O. U., Barragan A. P., Uvera S. G. R., Sandoval S., Tomas M. S., Sierra-Galan L. M., Siu S., Vallejo E., Valles M., Faraggi M., Sereegotov E., Ilic S., Ben-Rais N., Alaoui N. I., Taleb S., Myo K. P. P., Thu P. S., Ghimire R. K., Rajbanshi B., Barneveld P., Glaudemans A., Habets J., Koopmans K. P., Manders J., Pool S., Scholte A., Scholtens A., Slart R., Thimister P., Van Asperen E. -J., Veltman N., Verschure D., Wagenaar N., Edmond J., Ellis C., Johnson K., Keenan R., Kueh S. H., Occleshaw C., Sasse A., To A., Van Pelt N., Young C., Cuadra T., Vanegas H. B. R., Soli I. A., Issoufou D. M., Ayodele T., Madu C., Onimode Y., Efros-Monsen E., Forsdahl S. H., Dimmen J. -M. H., Jorgensen A., Krohn I., Lovhaugen P., Braten A. T., Al Dhuhli H., Al Kindi F., Al-Bulushi N., Jawa Z., Tag N., Afzal M. S., Fatima S., Younis M. N., Riaz M., Saadullah M., Herrera Y., Lenturut-Katal D., Vazquez M. C., Ortellado J., Akhter A., Cao D., Cheung S., Dai X., Gong L., Han D., Hou Y., Li C., Li T., Li D., Li S., Liu J., Liu H., Lu B., Ng M. Y., Sun K., Tang G., Wang J., Wang X., Wang Z. -Q., Wang Y., Wu J., Wu Z., Xia L., Xiao J., Xu L., Yang Y., Yin W., Yu J., Yuan L., Zhang T., Zhang L., Zhang Y. -G., Zhang X., Zhu L., Alfaro A., Abrihan P., Barroso A., Cruz E., Gomez M. R., Magboo V. P., Medina J. M., Obaldo J., Pastrana D., Pawhay C. M., Quinon A., Tang J. M., Tecson B., Uson K. J., Uy M., Kostkiewicz M., Kunikowska J., Bettencourt N., Cantinho G., Ferreira A., Syed G., Arnous S., Atyani S., Byrne A., Gleeson T., Kerins D., Meehan C., Murphy D., Murphy M., Murray J., O'Brien J., Bang J. -I., Bom H., Cho S. -G., Hong C. M., Jang S. J., Jeong Y. H., Kang W. J., Kim J. -Y., Namgung C. K., So Y., Won K. S., Majstorov V., Vavlukis M., Salobir B. G., Stalc M., Benedek T., Benedek I., Mititelu R., Stan C. A., Dariy O., Drozdova O., Gagarina N., Gulyaev V. M., Itskovich I., Karalkin A., Kokov A., Migunova E., Pospelov V., Ryzhkova D., Saifullina G., Sazonova S., Shurupova I., Trifonova T., Ussov W. Y., Vakhromeeva M., Valiullina N., Zavadovsky K., Zhuravlev K., Alasnag M., Okarvi S., Saranovic D. S., Keng F., See J. H. J., Sekar R., Yew M. S., Vondrak A., Bejai S., Bennie G., Bester R., Engelbrecht G., Evbuomwan O., Gongxeka H., Vuuren M. J., Kaplan M., Khushica P., Lakhi H., Louw L., Malan N., Milos K., Modiselle M., More S., Naidoo M., Scholtz L., Vangu M., Aguade-Bruix S., Blanco I., Cabrera A., Camarero A., Casans-Tormo I., Cuellar-Calabria H., Flotats A., Canamero M. E. F., Garcia M. E., Leta R., Diaz J. L., Lumbreras L., Marquez-Cabeza J. J., Martin F., De Alegria A. M., Medina F., Canal M. P., Peiro V., Pubul-Nunez V., Madrid J. I. R., Rey C. R., Perez R. R., Ruiz J., Hernandez G. S., Sevilla A., Zeidan N., Nanayakkara D., Udugama C., Simonsson M., Alkadhi H., Buechel R. R., Burger P., Ceriani L., De Boeck B., Grani C., De Saint Lager Lucas A. J., Kamani C. H., Kawel-Boehm N., Manka R., Prior J. O., Rominger A., Vallee J. -P., Khiewvan B., Premprabha T., Thientunyakit T., Sellem A., Kir K. M., Sayman H., Sebikali M. J., Muyinda Z., Kmetyuk Y., Korol P., Mykhalchenko O., Pliatsek V., Satyr M., Albalooshi B., Hassan M. I. A., Anderson J., Bedi P., Biggans T., Bularga A., Bull R., Burgul R., Carpenter J. -P., Coles D., Cusack D., Deshpande A., Dougan J., Fairbairn T., Farrugia A., Gopalan D., Gummow A., Ramkumar P. G., Hamilton M., Harbinson M., Hartley T., Hudson B., Joshi N., Kay M., Kelion A., Khokhar A., Kitt J., Low C., Mak S. M., Marousa N., Martin J., McAlindon E., Menezes L., Morgan-Hughes G., Moss A., Murray A., Patel D., Peebles C., Pugliese F., Rodrigues J. C. L., Rofe C., Sabharwal N., Schofield R., Semple T., Sharma N., Strouhal P., Subedi D., Topping W., Tweed K., Weir-Mccall J., Abbara S., Abbasi T., Abbott B., Abohashem S., Abramson S., Al-Abboud T., Al-Mallah M., Almousalli O., Ananthasubramaniam K., Kumar M. A., Askew J., Attanasio L., Balmer-Swain M., Bayer R. R., Bernheim A., Bhatti S., Bieging E., Blankstein R., Bloom S., Blue S., Bluemke D., Borges A., Branch K., Bravo P., Brothers J., Budoff M., Bullock-Palmer R., Burandt A., Burke F. W., Bush K., Candela C., Capasso E., Cavalcante J., Chang D., Chatterjee S., Chatzizisis Y., Cheezum M., Chen T., Chen J., Chen M., Choi A., Clarcq J., Cordero A., Crim M., Danciu S., Decter B., Dhruva N., Doherty N., Doukky R., Dunbar A., Duvall W., Edwards R., Esquitin K., Farah H., Fentanes E., Ferencik M., Fisher D., Fitzpatrick D., Foster C., Fuisz T., Gannon M., Gastner L., Gerson M., Ghoshhajra B., Goldberg A., Goldner B., Gonzalez J., Gore R., Gracia-Lopez S., Hage F., Haider A., Haider S., Hamirani Y., Hassen K., Hatfield M., Hawkins C., Hawthorne K., Heath N., Hendel R., Hernandez P., Hill G., Horgan S., Huffman J., Hurwitz L., Iskandrian A., Janardhanan R., Jellis C., Jerome S., Kalra D., Kaviratne S., Kay F., Kelly F., Khalique O., Kinkhabwala M., Iii G. K., Kircher J., Kirkbride R., Kontos M., Kottam A., Krepp J., Layer J., Lee S. H., Leppo J., Lesser J., Leung S., Lewin H., Litmanovich D., Liu Y., Lopez-Mattei J., Magurany K., Markowitz J., Marn A., Matis S. E., McKenna M., McRae T., Mendoza F., Merhige M., Min D., Moffitt C., Moncher K., Moore W., Morayati S., Morris M., Mossa-Basha M., Mrsic Z., Murthy V., Nagpal P., Napier K., Narula J., Nelson K., Nijjar P., Osman M., Parwani P., Passen E., Patel A., Patil P., Paul R., Phillips L., Polsani V., Poludasu R., Pomerantz B., Porter T., Prentice R., Pursnani A., Rabbat M., Ramamurti S., Rich F., Luna H. R., Robinson A., Robles K., Rodriguez C., Rorie M., Rumberger J., Russell R., Sabra P., Sadler D., Schemmer M., Schoepf U. J., Shah S., Shah N., Shanbhag S., Sharma G., Shayani S., Shirani J., Shivaram P., Sigman S., Simon M., Slim A., Smith D., Smith A., Soman P., Srichai-Parsia M. B., Streeter J., Albert T., Tawakol A., Thomas D., Thompson R., Torbet T., Trinidad D., Ullery S., Unzek S., Uretsky S., Vallurupalli S., Verma V., Waller A., Wang E., Ward P., Weissman G., Wesbey G., White K., Winchester D., Wolinsky D., Yost S., Zgaljardic M., Alonso O., Beretta M., Ferrando R., Kapitan M., Mut F., Djuraev O., Rozikhodjaeva G., Ngoc H. L., Mai S. H., Nguyen X. C., Williams, M, Shaw, L, Hirschfeld, C, Maurovich-Horvat, P, Norgaard, B, Pontone, G, Jimenez-Heffernan, A, Sinitsyn, V, Sergienko, V, Ansheles, A, Bax, J, Buechel, R, Milan, E, Slart, R, Nicol, E, Bucciarelli-Ducci, C, Pynda, Y, Better, N, Cerci, R, Dorbala, S, Raggi, P, Villines, T, Vitola, J, Malkovskiy, E, Goebel, B, Cohen, Y, Randazzo, M, Pascual, T, Dondi, M, Paez, D, Einstein, A, Nasery, M, Goda, A, Shirka, E, Benlabgaa, R, Bouyoucef, S, Medjahedi, A, Nailli, Q, Agolti, M, Aguero, R, Del Carmen Alak, M, Alberguina, L, Arronada, G, Astesiano, A, Norton, C, Benteo, P, Blanco, J, Bonelli, J, Bustos, J, Cabrejas, R, Cachero, J, Campisi, R, Canderoli, A, Carames, S, Carrascosa, P, Castro, R, Cendoya, O, Cognigni, L, Collaud, C, Cortes, C, Courtis, J, Cragnolino, D, Daicz, M, De La Vega, A, De Maria, S, Del Riego, H, Dettori, F, Deviggiano, A, Dragonetti, L, Embon, M, Enriquez, R, Ensinas, J, Faccio, F, Facello, A, Garofalo, D, Geronazzo, R, Gonza, N, Gutierrez, L, Guzzo, M, Hasbani, V, Huerin, M, Jager, V, Lewkowicz, J, De Munain, M, Lotti, J, Marquez, A, Masoli, O, Mastrovito, E, Mayoraz, M, Melado, G, Mele, A, Merani, M, Meretta, A, Molteni, S, Montecinos, M, Noguera, E, Novoa, C, Sueldo, C, Ascani, S, Pollono, P, Pujol, M, Radzinschi, A, Raimondi, G, Redruello, M, Rodriguez, M, Romero, R, Acuna, A, Rovaletti, F, Miguel, L, Solari, L, Strada, B, Traverso, S, Traverzo, S, Del Huerto Velazquez Espeche, M, Weihmuller, J, Wolcan, J, Zeffiro, S, Sakanyan, M, Beuzeville, S, Boktor, R, Butler, P, Calcott, J, Carr, L, Chan, V, Chao, C, Chong, W, Dobson, M, Downie, D, Dwivedi, G, Elison, B, Engela, J, Francis, R, Gaikwad, A, Basavaraj, A, Goodwin, B, Greenough, R, Hamilton-Craig, C, Hsieh, V, Joshi, S, Lederer, K, Lee, K, Lee, J, Magnussen, J, Mai, N, Mander, G, Murton, F, Nandurkar, D, Neill, J, O'Rourke, E, O'Sullivan, P, Pandos, G, Pathmaraj, K, Pitman, A, Poulter, R, Premaratne, M, Prior, D, Ridley, L, Rutherford, N, Salehi, H, Saunders, C, Scarlett, L, Seneviratne, S, Shetty, D, Shrestha, G, Shulman, J, Solanki, V, Stanton, T, Stuart, M, Stubbs, M, Swainson, I, Taubman, K, Taylor, A, Thomas, P, Unger, S, Upton, A, Vamadevan, S, Van Gaal, W, Verjans, J, Voutnis, D, Wayne, V, Wilson, P, Wong, D, Wong, K, Younger, J, Feuchtner, G, Mirzaei, S, Weiss, K, Maroz-Vadalazhskaya, N, Gheysens, O, Homans, F, Moreno-Reyes, R, Pasquet, A, Roelants, V, Van De Heyning, C, Rios, R, Soldat-Stankovic, V, Stankovic, S, Siqueira, M, Almeida, A, Togni, P, Andrade, J, Andrade, L, Anselmi, C, Araujo, R, Azevedo, G, Bezerra, S, Biancardi, R, Grossman, G, Brandao, S, Pianta, D, Carreira, L, Castro, B, Chang, T, Cunali, F, Cury, R, Dantas, R, De Amorim Fernandes, F, De Lorenzo, A, De MacEdo Filho, R, Erthal, F, Fernandes, F, Fernandes, J, De Souza, T, Alves, W, Ghini, B, Goncalves, L, Gottlieb, I, Hadlich, M, Kameoka, V, Lima, R, Lima, A, Lopes, R, E Silva, R, Magalhaes, T, Silva, F, Mastrocola, L, Medeiros, F, Meneghetti, J, Naue, V, Naves, D, Nolasco, R, Nomura, C, Oliveira, J, Paixao, E, De Carvalho, F, Pinto, I, Possetti, P, Quinta, M, Ramos, R, Rocha, R, Rodrigues, A, Rodrigues, C, Romantini, L, Sanches, A, Santana, S, Da Silva, L, Schvartzman, P, Matushita, C, Senra, T, Shiozaki, A, De Siqueira, M, Siqueira, C, Smanio, P, Soares, C, Soares, J, Bittencourt, M, Spiro, B, Mesquita, C, Torreao, J, Torres, R, Uellendahl, M, Monte, G, Verissimo, O, Cabeda, E, Pedras, F, Waltrick, R, Zapparoli, M, Naseer, H, Garcheva-Tsacheva, M, Kostadinova, I, Theng, Y, Abikhzer, G, Barette, R, Chow, B, Dabreo, D, Friedrich, M, Garg, R, Hafez, M, Johnson, C, Kiess, M, Leipsic, J, Leung, E, Miller, R, Oikonomou, A, Probst, S, Roifman, I, Small, G, Tandon, V, Trivedi, A, White, J, Zukotynski, K, Canessa, J, Munoz, G, Concha, C, Hidalgo, P, Lovera, C, Massardo, T, Vargas, L, Abad, P, Arturo, H, Ayala, S, Benitez, L, Cadena, A, Caicedo, C, Moncayo, A, Gomez, S, Villamil, C, Jaimes, C, Londono, J, Blair, J, Pabon, L, Pineda, M, Rojas, J, Ruiz, D, Escobar, M, Vasquez, 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G, Bester, R, Engelbrecht, G, Evbuomwan, O, Gongxeka, H, Vuuren, M, Kaplan, M, Khushica, P, Lakhi, H, Louw, L, Malan, N, Milos, K, Modiselle, M, More, S, Naidoo, M, Scholtz, L, Vangu, M, Aguade-Bruix, S, Blanco, I, Cabrera, A, Camarero, A, Casans-Tormo, I, Cuellar-Calabria, H, Flotats, A, Canamero, M, Garcia, M, Leta, R, Diaz, J, Lumbreras, L, Marquez-Cabeza, J, Martin, F, De Alegria, A, Medina, F, Canal, M, Peiro, V, Pubul-Nunez, V, Madrid, J, Rey, C, Perez, R, Ruiz, J, Hernandez, G, Sevilla, A, Zeidan, N, Nanayakkara, D, Udugama, C, Simonsson, M, Alkadhi, H, Burger, P, Ceriani, L, De Boeck, B, Grani, C, De Saint Lager Lucas, A, Kamani, C, Kawel-Boehm, N, Manka, R, Prior, J, Rominger, A, Vallee, J, Khiewvan, B, Premprabha, T, Thientunyakit, T, Sellem, A, Kir, K, Sayman, H, Sebikali, M, Muyinda, Z, Kmetyuk, Y, Korol, P, Mykhalchenko, O, Pliatsek, V, Satyr, M, Albalooshi, B, Anderson, J, Bedi, P, Biggans, T, Bularga, A, Bull, R, Burgul, R, Carpenter, J, Coles, D, Cusack, D, Deshpande, A, Dougan, J, Fairbairn, T, Farrugia, A, Gopalan, D, Gummow, A, Ramkumar, P, Hamilton, M, Harbinson, M, Hartley, T, Hudson, B, Joshi, N, Kay, M, Kelion, A, Khokhar, A, Kitt, J, Low, C, Mak, S, Marousa, N, Martin, J, Mcalindon, E, Menezes, L, Morgan-Hughes, G, Moss, A, Murray, A, Patel, D, Peebles, C, Pugliese, F, Rodrigues, J, Rofe, C, Sabharwal, N, Schofield, R, Semple, T, Sharma, N, Strouhal, P, Subedi, D, Topping, W, Tweed, K, Weir-Mccall, J, Abbara, S, Abbasi, T, Abbott, B, Abohashem, S, Abramson, S, Al-Abboud, T, Al-Mallah, M, Almousalli, O, Ananthasubramaniam, K, Kumar, M, Askew, J, Attanasio, L, Balmer-Swain, M, Bayer, R, Bernheim, A, Bhatti, S, Bieging, E, Blankstein, R, Bloom, S, Blue, S, Bluemke, D, Borges, A, Branch, K, Bravo, P, Brothers, J, Budoff, M, Bullock-Palmer, R, Burandt, A, Burke, F, Bush, K, Candela, C, Capasso, E, Cavalcante, J, Chang, D, Chatterjee, S, Chatzizisis, Y, Cheezum, M, Chen, T, Chen, J, Chen, M, Choi, A, Clarcq, J, Cordero, A, Crim, M, Danciu, S, Decter, B, Dhruva, N, Doherty, N, Doukky, R, Dunbar, A, Duvall, W, Edwards, R, Esquitin, K, Farah, H, Fentanes, E, Ferencik, M, Fisher, D, Fitzpatrick, D, Foster, C, Fuisz, T, Gannon, M, Gastner, L, Gerson, M, Ghoshhajra, B, Goldberg, A, Goldner, B, Gonzalez, J, Gore, R, Gracia-Lopez, S, Hage, F, Haider, A, Haider, S, Hamirani, Y, Hassen, K, Hatfield, M, Hawkins, C, Hawthorne, K, Heath, N, Hendel, R, Hernandez, P, Hill, G, Horgan, S, Huffman, J, Hurwitz, L, Iskandrian, A, Janardhanan, R, Jellis, C, Jerome, S, Kalra, D, Kaviratne, S, Kay, F, Kelly, F, Khalique, O, Kinkhabwala, M, Iii, G, Kircher, J, Kirkbride, R, Kontos, M, Kottam, A, Krepp, J, Layer, J, Lee, S, Leppo, J, Lesser, J, Leung, S, Lewin, H, Litmanovich, D, Liu, Y, Lopez-Mattei, J, Magurany, K, Markowitz, J, Marn, A, Matis, S, Mckenna, M, Mcrae, T, Mendoza, F, Merhige, M, Min, D, Moffitt, C, Moncher, K, Moore, W, Morayati, S, Morris, M, Mossa-Basha, M, Mrsic, Z, Murthy, V, Nagpal, P, Napier, K, Narula, J, Nelson, K, Nijjar, P, Osman, M, Parwani, P, Passen, E, Patel, A, Patil, P, Paul, R, Phillips, L, Polsani, V, Poludasu, R, Pomerantz, B, Porter, T, Prentice, R, Pursnani, A, Rabbat, M, Ramamurti, S, Rich, F, Luna, H, Robinson, A, Robles, K, Rodriguez, C, Rorie, M, Rumberger, J, Russell, R, Sabra, P, Sadler, D, Schemmer, M, Schoepf, U, Shah, S, Shah, N, Shanbhag, S, Sharma, G, Shayani, S, Shirani, J, Shivaram, P, Sigman, S, Simon, M, Slim, A, Smith, D, Smith, A, Soman, P, Srichai-Parsia, M, Streeter, J, Albert, T, Tawakol, A, Thomas, D, Thompson, R, Torbet, T, Trinidad, D, Ullery, S, Unzek, S, Uretsky, S, Vallurupalli, S, Verma, V, Waller, A, Wang, E, Ward, P, Weissman, G, Wesbey, G, White, K, Winchester, D, Wolinsky, D, Yost, S, Zgaljardic, M, Alonso, O, Beretta, M, Ferrando, R, Kapitan, M, Mut, F, Djuraev, O, Rozikhodjaeva, G, Ngoc, H, Mai, S, Nguyen, X, ​Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Translational Immunology Groningen (TRIGR), and Cardiovascular Centre (CVC)

Subjects
INCAPS COVID Investigators Group, cardiac imaging techniques, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, Practice Patterns, Disease, Cardiovascular, coronary artery disease, COVID-19, Cardiac Imaging Techniques, Cardiologists, Europe, Health Care Surveys, Healthcare Disparities, Heart Diseases, Humans, Practice Patterns, Physicians', Predictive Value of Tests, Gross domestic product, Human health, cardiovascular disease, Pandemic, Medicine, cardiovascular imaging, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina, cardiac imaging technique, Predictive value of tests, Cardiology and Cardiovascular Medicine, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Infektologija, cardiac disease, Coronavirus disease 2019 (COVID-19), Independent predictor, cardiac imaging, NO, Imaging diagnosis, Diseases of the circulatory (Cardiovascular) system, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine, Physicians', business.industry, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Infectology, RC666-701, HOSPITALIZATIONS, business, Health Care Delivery, Economics and Global Health Care, Demography
Abstract

ObjectivesWe aimed to explore the impact of the COVID-19 pandemic on cardiac diagnostic testing and practice and to assess its impact in different regions in Europe.MethodsThe online survey organised by the International Atomic Energy Agency Division of Human Health collected information on changes in cardiac imaging procedural volumes between March 2019 and March/April 2020. Data were collected from 909 centres in 108 countries.ResultsCentres in Northern and Southern Europe were more likely to cancel all outpatient activities compared with Western and Eastern Europe. There was a greater reduction in total procedure volumes in Europe compared with the rest of the world in March 2020 (45% vs 41%, p=0.003), with a more marked reduction in Southern Europe (58%), but by April 2020 this was similar in Europe and the rest of the world (69% vs 63%, p=0.261). Regional variations were apparent between imaging modalities, but the largest reductions were in Southern Europe for nearly all modalities. In March 2020, location in Southern Europe was the only independent predictor of the reduction in procedure volume. However, in April 2020, lower gross domestic product and higher COVID-19 deaths were the only independent predictors.ConclusionThe first wave of the COVID-19 pandemic had a significant impact on care of patients with cardiac disease, with substantial regional variations in Europe. This has potential long-term implications for patients and plans are required to enable the diagnosis of non-COVID-19 conditions during the ongoing pandemic.

Published
2021

16. Impact of COVID-19 Pandemic on Cardiovascular Testing in Asia: The IAEA INCAPS-COVID Study

Author

Kudo, T., Lahey, R., Hirschfeld, C.B., Williams, M.C., Lu, B., Alasnag, M., Bhatia, M., Henry Bom, H.-., Dautov, T., Fazel, R., Karthikeyan, G., Keng, F.Y.J., Rubinshtein, R., Better, N., Cerci, R.J., Dorbala, S., Raggi, P., Shaw, L.J., Villines, T.C., Vitola, J.V., Choi, A.D., Malkovskiy, E., Goebel, B., Cohen, Y.A., Randazzo, M., Pascual, T.N.B., Pynda, Y., Dondi, M., Paez, D., Einstein, A.J., Cerci, R., Hinterleitner, G., Lu, Y., Morozova, O., Xu, Z., Cohen, Y., Choi, A., Lopez-Mattei, J., Parwani, P., Nasery, M.N., Goda, A., Shirka, E., Benlabgaa, R., Bouyoucef, S., Medjahedi, A., Nailli, Q., Agolti, M., Aguero, R.N., Alak, M.D.C., Alberguina, L.G., Arronada, G., Astesiano, A., Norton, C.B., Benteo, P., Blanco, J., Bonelli, J.M., Bustos, J.J., Cabrejas, R., Cachero, J., Campisi, R., Canderoli, A., Carames, S., Carrascosa, P., Castro, R., Cendoya, O., Cognigni, L.M., Collaud, C., Cortes, C., Courtis, J., Cragnolino, D., Daicz, M., De La Vega, A., De Maria, S.T., Del Riego, H., Dettori, F., Deviggiano, A., Dragonetti, L., Embon, M., Enriquez, R.E., Ensinas, J., Faccio, F., Facello, A., Garofalo, D., Geronazzo, R., Gonza, N., Gutierrez, L., Guzzo, M.A., Hasbani, V., Huerin, M., Jager, V., Lewkowicz, J.M., Lopez De Munain, M.N.A., Lotti, J.M., Marquez, A., Masoli, O., Masoli, O.H., Mastrovito, E., Mayoraz, M., Melado, G.E., Mele, A., Merani, M.F., Meretta, A.H., Molteni, S., Montecinos, M., Noguera, E., Novoa, C., Sueldo, C.P., Ascani, S.P., Pollono, P., Pujol, M.P., Radzinschi, A., Raimondi, G., Redruello, M., Rodriguez, M., Romero, R.L., Acuna, A.R., Rovaletti, F., San Miguel, L., Solari, L., Strada, B., Traverso, S., Traverzo, S.S., Espeche, M.D.H.V., Weihmuller, J.S., Wolcan, J., Zeffiro, S., Sakanyan, M., Beuzeville, S., Boktor, R., Butler, P., Calcott, J., Carr, L., Chan, V., Chao, C., Chong, W., Dobson, M., Downie, D.A., Dwivedi, G., Elison, B., Engela, J., Francis, R., Gaikwad, A., Basavaraj, A.G., Goodwin, B., Greenough, R., Hamilton-Craig, C., Hsieh, V., Joshi, S., Lederer, K., Lee, K., Lee, J., Magnussen, J., Mai, N., Mander, G., Murton, F., Nandurkar, D., Neill, J., O'Rourke, E., O'Sullivan, P., Pandos, G., Pathmaraj, K., Pitman, A., Poulter, R., Premaratne, M., Prior, D., Ridley, L., Rutherford, N., Salehi, H., Saunders, C., Scarlett, L., Seneviratne, S., Shetty, D., Shrestha, G., Shulman, J., Solanki, V., Stanton, T., Stuart, M., Stubbs, M., Swainson, I., Taubman, K., Taylor, A., Thomas, P., Unger, S., Upton, A., Vamadevan, S., Van Gaal, W., Verjans, J., Voutnis, D., Wayne, V., Wilson, P., Wong, D., Wong, K., Younger, J., Feuchtner, G., Mirzaei, S., Weiss, K., Maroz-Vadalazhskaya, N., Gheysens, O., Homans, F., Moreno-Reyes, R., Pasquet, A., Roelants, V., Van De Heyning, C.M., Rios, R.A., Soldat-Stankovic, V., Stankovic, S., Albernaz Siqueira, M.H., Almeida, A., Alves Togni, P.H., Andrade, J.H., Andrade, L., Anselmi, C., Araujo, R., Azevedo, G., Bezerra, S., Biancardi, R., Grossman, G.B., Brandao, S., Pianta, D.B., Carreira, L., Castro, B., Chang, T., Cunali, F., Cury, R., Dantas, R., de Amorim Fernandes, F., De Lorenzo, A., De Macedo Filho, R., Erthal, F., Fernandes, F., Fernandes, J., De Souza, T.F., Alves, W.F., Ghini, B., Goncalves, L., Gottlieb, I., Hadlich, M., Kameoka, V., Lima, R., Lima, A., Lopes, R.W., Machado e Silva, R., Magalhaes, T., Silva, F.M., Mastrocola, L.E., Medeiros, F., Meneghetti, J.C., Naue, V., Naves, D., Nolasco, R., Nomura, C., Oliveira, J.B., Paixao, E., De Carvalho, F.P., Pinto, I., Possetti, P., Quinta, M., Nogueira Ramos, R.R., Rocha, R., Rodrigues, A., Rodrigues, C., Romantini, L., Sanches, A., Santana, S., Sara da Silva, L., Schvartzman, P., Matushita, C.S., Senra, T., Shiozaki, A., Menezes de Siqueira, M.E., Siqueira, C., Smanio, P., Soares, C.E., Junior, J.S., Bittencourt, M.S., Spiro, B., Mesquita, C.T., Torreao, J., Torres, R., Uellendahl, M., Monte, G.U., Verissimo, O., Cabeda, E.V., Pedras, F.V., Waltrick, R., Zapparoli, M., Naseer, H., Garcheva-Tsacheva, M., Kostadinova, I., Theng, Y., Abikhzer, G., Barette, R., Chow, B., Dabreo, D., Friedrich, M., Garg, R., Hafez, M.N., Johnson, C., Kiess, M., Leipsic, J., Leung, E., Miller, R., Oikonomou, A., Probst, S., Roifman, I., Small, G., Tandon, V., Trivedi, A., White, J., Zukotynski, K., Canessa, J., Munoz, G.C., Concha, C., Hidalgo, P., Lovera, C., Massardo, T., Vargas, L.S., Abad, P., Arturo, H., Ayala, S., Benitez, L., Cadena, A., Caicedo, C., Moncayo, A.C., Gomez, S., Gutierrez Villamil, C.T., Jaimes, C., Londono, J., Londono Blair, J.L., Pabon, L., Pineda, M., Rojas, J.C., Ruiz, D., Escobar, M.V., Vasquez, A., Vergel, D., Zuluaga, A., Gamboa, I.B., Castro, G., Gonzalez, U., Baric, A., Batinic, T., Franceschi, M., Paar, M.H., Jukic, M., Medakovic, P., Persic, V., Prpic, M., Punda, A., Batista, J.F., Gomez Lauchy, J.M., Gutierrez, Y.M., Menendez, R., Peix, A., Rochela, L., Panagidis, C., Petrou, I., Engelmann, V., Kaminek, M., Kincl, V., Lang, O., Simanek, M., Abdulla, J., Bottcher, M., Christensen, M., Gormsen, L.C., Hasbak, P., Hess, S., Holdgaard, P., Johansen, A., Kyhl, K., Norgaard, B.L., Ovrehus, K.A., Ronnow Sand, N.P., Steffensen, R., Thomassen, A., Zerahn, B., Perez, A., Escorza Velez, G.A., Velez, M.S., Abdel Aziz, I.S., Abougabal, M., Ahmed, T., Allam, A., Asfour, A., Hassan, M., Hassan, A., Ibrahim, A., Kaffas, S., Kandeel, A., Ali, M.M., Mansy, A., Maurice, H., Nabil, S., Shaaban, M., Flores, A.C., Poksi, A., Knuuti, J., Kokkonen, V., Larikka, M., Uusitalo, V., Bailly, M., Burg, S., Deux, J.-., Habouzit, V., Hyafil, F., Lairez, O., Proffit, F., Regaieg, H., Sarda-Mantel, L., Tacher, V., Schneider, R.P., Ayetey, H., Angelidis, G., Archontaki, A., Chatziioannou, S., Datseris, I., Fragkaki, C., Georgoulias, P., Koukouraki, S., Koutelou, M., Kyrozi, E., Repasos, E., Stavrou, P., Valsamaki, P., Gonzalez, C., Gutierrez, G., Maldonado, A., Buga, K., Garai, I., Maurovich-Horvat, P., Schmidt, E., Szilveszter, B., Varady, E., Banthia, N., Bhagat, J.K., Bhargava, R., Bhat, V., Choudhury, P., Chowdekar, V.S., Irodi, A., Jain, S., Joseph, E., Kumar, S., Girijanandan Mahapatra, P.D., Mitra, D., Mittal, B.R., Ozair, A., Patel, C., Patel, T., Patel, R., Patel, S., Saxena, S., Sengupta, S., Singh, S., Singh, B., Sood, A., Verma, A., Affandi, E., Alam, P.S., Edison, E., Gunawan, G., Hapkido, H., Hidayat, B., Huda, A., Mukti, A.P., Prawiro, D., Soeriadi, E.A., Syawaluddin, H., Albadr, A., Assadi, M., Emami, F., Houshmand, G., Maleki, M., Rostami, M.T., Zakavi, S.R., Zaid, E.A., Agranovich, S., Arnson, Y., Bar-Shalom, R., Frenkel, A., Knafo, G., Lugassi, R., Maor Moalem, I.S., Mor, M., Muskal, N., Ranser, S., Shalev, A., Albano, D., Alongi, P., Arnone, G., Bagatin, E., Baldari, S., Bauckneht, M., Bertelli, P., Bianco, F., Bonfiglioli, R., Boni, R., Bruno, A., Bruno, I., Busnardo, E., Califaretti, E., Camoni, L., Carnevale, A., Casoni, R., Cavallo, A.U., Cavenaghi, G., Chierichetti, F., Chiocchi, M., Cittanti, C., Colletta, M., Conti, U., Cossu, A., Cuocolo, A., Cuzzocrea, M., De Rimini, M.L., De Vincentis, G., Del Giudice, E., Del Torto, A., Della Tommasina, V., Durmo, R., Erba, P.A., Evangelista, L., Faletti, R., Faragasso, E., Farsad, M., Ferro, P., Florimonte, L., Frantellizzi, V., Fringuelli, F.M., Gatti, M., Gaudiano, A., Gimelli, A., Giubbini, R., Giuffrida, F., Ialuna, S., Laudicella, R., Leccisotti, L., Leva, L., Liga, R., Liguori, C., Longo, G., Maffione, M., Mancini, M.E., Marcassa, C., Milan, E., Nardi, B., Pacella, S., Pepe, G., Pontone, G., Pulizzi, S., Quartuccio, N., Rampin, L., Ricci, F., Rossini, P., Rubini, G., Russo, V., Sacchetti, G.M., Sambuceti, G., Scarano, M., Sciagra, R., Sperandio, M., Stefanelli, A., Ventroni, G., Zoboli, S., Baugh, D., Chambers, D., Madu, E., Nunura, F., Asano, H., Chimura, C.M., Fujimoto, S., Fujisue, K., Fukunaga, T., Fukushima, Y., Fukuyama, K., Hashimoto, J., Ichikawa, Y., Iguchi, N., Imai, M., Inaki, A., Ishimura, H., Isobe, S., Kadokami, T., Kato, T., Kumita, S., Maruno, H., Mataki, H., Miyagawa, M., Morimoto, R., Moroi, M., Nagamachi, S., Nakajima, K., Nakata, T., Nakazato, R., Nanasato, M., Naya, M., Norikane, T., Ohta, Y., Okayama, S., Okizaki, A., Otomi, Y., Otsuka, H., Saito, M., Sakata, S.Y., Sarai, M., Sato, D., Shiraishi, S., Suwa, Y., Takanami, K., Takehana, K., Taki, J., Tamaki, N., Taniguchi, Y., Teragawa, H., Tomizawa, N., Tsujita, K., Umeji, K., Wakabayashi, Y., Yamada, S., Yamazaki, S., Yoneyama, T., Rawashdeh, M., Batyrkhanov, D., Makhdomi, K., Ombati, K., Alkandari, F., Garashi, M., Coie, T.L., Rajvong, S., Kalinin, A., Kalnina, M., Haidar, M., Komiagiene, R., Kviecinskiene, G., Mataciunas, M., Vajauskas, D., Picard, C., Karim, N.K.A., Reichmuth, L., Samuel, A., Allarakha, M.A., Naojee, A.S., Alexanderson-Rosas, E., Barragan, E., Gonzalez-Montecinos, A.B., Cabada, M., Rodriguez, D.C., Carvajal-Juarez, I., Cortes, V., Cortes, F., De La Pena, E., Gama-Moreno, M., Gonzalez, L., Ramirez, N.G., Jimenez-Santos, M., Matos, L., Monroy, E., Morelos, M., Ornelas, M., Ortga Ramirez, J.A., Preciado-Anaya, A., Preciado-Gutierrez, O.U., Barragan, A.P., Rosales Uvera, S.G., Sandoval, S., Tomas, M.S., Sierra-Galan, L.M., Siu, S., Vallejo, E., Valles, M., Faraggi, M., Sereegotov, E., Ilic, S., Ben-Rais, N., Alaoui, N.I., Taleb, S., Pa Myo, K.P., Thu, P.S., Ghimire, R.K., Rajbanshi, B., Barneveld, P., Glaudemans, A., Habets, J., Koopmans, K.P., Manders, J., Pool, S., Scholte, A., Scholtens, A., Slart, R., Thimister, P., Van Asperen, E.-., Veltman, N., Verschure, D., Wagenaar, N., Edmond, J., Ellis, C., Johnson, K., Keenan, R., Kueh, S.H.A., Occleshaw, C., Sasse, A., To, A., Van Pelt, N., Young, C., Cuadra, T., Roque Vanegas, H.B., Soli, I.A., Issoufou, D.M., Ayodele, T., Madu, C., Onimode, Y., Efros-Monsen, E., Forsdahl, S.H., Hildre Dimmen, J.-., Jorgensen, A., Krohn, I., Lovhaugen, P., Braten, A.T., Al Dhuhli, H., Al Kindi, F., Al-Bulushi, N., Jawa, Z., Tag, N., Afzal, M.S., Fatima, S., Younis, M.N., Riaz, M., Saadullah, M., Herrera, Y., Lenturut-Katal, D., Vazquez, M.C., Ortellado, J., Akhter, A., Cao, D., Cheung, S., Dai, X., Gong, L., Han, D., Hou, Y., Li, C., Li, T., Li, D., Li, S., Liu, J., Liu, H., M. Y., N., Sun, K., Tang, G., Wang, J., Wang, X., Wang, Z.-., Wang, Y., Wu, J., Wu, Z., Xia, L., Xiao, J., Xu, L., Yang, Y., Yin, W., Yu, J., Yuan, L., Zhang, T., Zhang, L., Zhang, Y.-., Zhang, X., Zhu, L., Alfaro, A., Abrihan, P., Barroso, A., Cruz, E., Gomez, M.R., Magboo, V.P., Medina, J.M., Obaldo, J., Pastrana, D., Pawhay, C.M., Quinon, A., Tang, J.M., Tecson, B., Uson, K.J., Uy, M., Kostkiewicz, M., Kunikowska, J., Bettencourt, N., Cantinho, G., Ferreira, A., Syed, G., Arnous, S., Atyani, S., Byrne, A., Gleeson, T., Kerins, D., Meehan, C., Murphy, D., Murphy, M., Murray, J., O'Brien, J., Bang, J.-., Bom, H., Cho, S.-., Hong, C.M., Jang, S.J., Jeong, Y.H., Kang, W.J., Kim, J.-., Namgung, C.K., So, Y., Won, K.S., Majstorov, V., Vavlukis, M., Salobir, B.G., Stalc, M., Benedek, T., Benedek, I., Mititelu, R., Stan, C.A., Ansheles, A., Dariy, O., Drozdova, O., Gagarina, N., Gulyaev, V.M., Itskovich, I., Karalkin, A., Kokov, A., Migunova, E., Pospelov, V., Ryzhkova, D., Saifullina, G., Sazonova, S., Sergienko, V., Shurupova, I., Trifonova, T., Ussov, W.Y., Vakhromeeva, M., Valiullina, N., Zavadovsky, K., Zhuravlev, K., Okarvi, S., Saranovic, D.S., Keng, F., Jason See, J.H., Sekar, R., Yew, M.S., Vondrak, A., Bejai, S., Bennie, G., Bester, R., Engelbrecht, G., Evbuomwan, O., Gongxeka, H., Vuuren, M.J., Kaplan, M., Khushica, P., Lakhi, H., Louw, L., Malan, N., Milos, K., Modiselle, M., More, S., Naidoo, M., Scholtz, L., Vangu, M., Aguade-Bruix, S., Blanco, I., Cabrera, A., Camarero, A., Casans-Tormo, I., Cuellar-Calabria, H., Flotats, A., Fuentes Canamero, M.E., Garcia, M.E., Jimenez-Heffernan, A., Leta, R., Diaz, J.L., Lumbreras, L., Marquez-Cabeza, J.J., Martin, F., Martinez de Alegria, A., Medina, F., Canal, M.P., Peiro, V., Pubul-Nunez, V., Rayo Madrid, J.I., Rey, C.R., Perez, R.R., Ruiz, J., Hernandez, G.S., Sevilla, A., Zeidan, N., Nanayakkara, D., Udugama, C., Simonsson, M., Alkadhi, H., Buechel, R.R., Burger, P., Ceriani, L., De Boeck, B., Grani, C., Juillet de Saint Lager Lucas, A., Kamani, C.H., Kawel-Boehm, N., Manka, R., Prior, J.O., Rominger, A., Vallee, J.-., Khiewvan, B., Premprabha, T., Thientunyakit, T., Sellem, A., Kir, K.M., Sayman, H., Sebikali, M.J., Muyinda, Z., Kmetyuk, Y., Korol, P., Mykhalchenko, O., Pliatsek, V., Satyr, M., Albalooshi, B., Ahmed Hassan, M.I., Anderson, J., Bedi, P., Biggans, T., Bularga, A., Bull, R., Burgul, R., Carpenter, J.-., Coles, D., Cusack, D., Deshpande, A., Dougan, J., Fairbairn, T., Farrugia, A., Gopalan, D., Gummow, A., Ramkumar, P.G., Hamilton, M., Harbinson, M., Hartley, T., Hudson, B., Joshi, N., Kay, M., Kelion, A., Khokhar, A., Kitt, J., Low, C., Mak, S.M., Marousa, N., Martin, J., Mcalindon, E., Menezes, L., Morgan-Hughes, G., Moss, A., Murray, A., Nicol, E., Patel, D., Peebles, C., Pugliese, F., Luis Rodrigues, J.C., Rofe, C., Sabharwal, N., Schofield, R., Semple, T., Sharma, N., Strouhal, P., Subedi, D., Topping, W., Tweed, K., Weir-Mccall, J., Abbara, S., Abbasi, T., Abbott, B., Abohashem, S., Abramson, S., Al-Abboud, T., Al-Mallah, M., Almousalli, O., Ananthasubramaniam, K., Kumar, M.A., Askew, J., Attanasio, L., Balmer-Swain, M., Bayer, R.R., Bernheim, A., Bhatti, S., Bieging, E., Blankstein, R., Bloom, S., Blue, S., Bluemke, D., Borges, A., Branch, K., Bravo, P., Brothers, J., Budoff, M., Bullock-Palmer, R., Burandt, A., Burke, F.W., Bush, K., Candela, C., Capasso, E., Cavalcante, J., Chang, D., Chatterjee, S., Chatzizisis, Y., Cheezum, M., Chen, T., Chen, J., Chen, M., Clarcq, J., Cordero, A., Crim, M., Danciu, S., Decter, B., Dhruva, N., Doherty, N., Doukky, R., Dunbar, A., Duvall, W., Edwards, R., Esquitin, K., Farah, H., Fentanes, E., Ferencik, M., Fisher, D., Fitzpatrick, D., Foster, C., Fuisz, T., Gannon, M., Gastner, L., Gerson, M., Ghoshhajra, B., Goldberg, A., Goldner, B., Gonzalez, J., Gore, R., Gracia-Lopez, S., Hage, F., Haider, A., Haider, S., Hamirani, Y., Hassen, K., Hatfield, M., Hawkins, C., Hawthorne, K., Heath, N., Hendel, R., Hernandez, P., Hill, G., Horgan, S., Huffman, J., Hurwitz, L., Iskandrian, A., Janardhanan, R., Jellis, C., Jerome, S., Kalra, D., Kaviratne, S., Kay, F., Kelly, F., Khalique, O., Kinkhabwala, M., Iii, G.K., Kircher, J., Kirkbride, R., Kontos, M., Kottam, A., Krepp, J., Layer, J., Lee, S.H., Leppo, J., Lesser, J., Leung, S., Lewin, H., Litmanovich, D., Liu, Y., Magurany, K., Markowitz, J., Marn, A., Matis, S.E., Mckenna, M., Mcrae, T., Mendoza, F., Merhige, M., Min, D., Moffitt, C., Moncher, K., Moore, W., Morayati, S., Morris, M., Mossa-Basha, M., Mrsic, Z., Murthy, V., Nagpal, P., Napier, K., Nelson, K., Nijjar, P., Osman, M., Passen, E., Patel, A., Patil, P., Paul, R., Phillips, L., Polsani, V., Poludasu, R., Pomerantz, B., Porter, T., Prentice, R., Pursnani, A., Rabbat, M., Ramamurti, S., Rich, F., Luna, H.R., Robinson, A., Robles, K., Rodriguez, C., Rorie, M., Rumberger, J., Russell, R., Sabra, P., Sadler, D., Schemmer, M., Schoepf, U.J., Shah, S., Shah, N., Shanbhag, S., Sharma, G., Shayani, S., Shirani, J., Shivaram, P., Sigman, S., Simon, M., Slim, A., Smith, D., Smith, A., Soman, P., Srichai-Parsia, M.B., Streeter, J., T, A., Tawakol, A., Thomas, D., Thompson, R., Torbet, T., Trinidad, D., Ullery, S., Unzek, S., Uretsky, S., Vallurupalli, S., Verma, V., Waller, A., Wang, E., Ward, P., Weissman, G., Wesbey, G., White, K., Winchester, D., Wolinsky, D., Yost, S., Zgaljardic, M., Alonso, O., Beretta, M., Ferrando, R., Kapitan, M., Mut, F., Djuraev, O., Rozikhodjaeva, G., Le Ngoc, H., Mai, S.H., and Nguyen, X.C.

Subjects
INCAPS COVID Investigators Group, Pediatric Research Initiative, positron emission tomography, CTA, SARS-CoV-2, cardiac testing, invasive coronary angiography, Prevention, coronavirus, coronavirus disease-19, COVID-19, global health, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, cardiac magnetic resonance, cardiovascular disease, NO, transthoracic echocardiography, PET, Good Health and Well Being, severe acute respiratory syndrome-coronavirus-2, TTE, ICA, CMR, computed tomographic angiography
Abstract

BackgroundThe coronavirus disease-2019 (COVID-19) pandemic significantly affected management of cardiovascular disease around the world. The effect of the pandemic on volume of cardiovascular diagnostic procedures is not known.ObjectivesThis study sought to evaluate the effects of the early phase of the COVID-19 pandemic on cardiovascular diagnostic procedures and safety practices in Asia.MethodsThe International Atomic Energy Agency conducted a worldwide survey to assess changes in cardiovascular procedure volume and safety practices caused by COVID-19. Testing volumes were reported for March 2020 and April 2020 and were compared to those from March 2019. Data from 180 centers across 33 Asian countries were grouped into 4 subregions for comparison.ResultsProcedure volumes decreased by 47% from March 2019 to March 2020, showing recovery from March 2020 to April 2020 in Eastern Asia, particularly in China. The majority of centers cancelled outpatient activities and increased time per study. Practice changes included implementing physical distancing and restricting visitors. Although COVID testing was not commonly performed, it was conducted in one-third of facilities in Eastern Asia. The most severe reductions in procedure volumes were observed in lower-income countries, where volumes decreased 81% from March 2019 to April2020.ConclusionsThe COVID-19 pandemic in Asia caused significant reductions in cardiovascular diagnostic procedures, particularly in low-income countries. Further studies on effects of COVID-19 on cardiovascular outcomes and changes in care delivery are warranted.

Published
2021

19. Abnormal electron beam computed tomography results: the value of repeating myocardial perfusion single-photon emission computed tomography in the ongoing assessment of coronary artery disease

Author

Askew, J. Wells, Miller, Todd D., Araoz, Philip A., Breen, Jerome F., Hodge, David O., and Gibbons, Raymond J.

Subjects
SPECT imaging -- Usage, Coronary heart disease -- Risk factors, Atherosclerosis -- Diagnosis, Atherosclerosis -- Research, Calcium, Dietary -- Measurement
Abstract

OBJECTIVE: To determine whether asymptomatic patients with atherosclerosis, indicated by the presence of coronary artery calcium on electron beam computed tomography, are at enough risk for progression of disease to [...]

Published
2008

25. Characterization of Aerosol Generation During Various Intensities of Exercise.

Author

Sajgalik, Pavol, Garzona-Navas, Andres, Csécs, Ibolya, Askew, J. Wells, Lopez-Jimenez, Francisco, Niven, Alexander S., Johnson, Bruce D., and Allison, Thomas G.

Abstract

Background: Characterization of aerosol generation during exercise can inform the development of safety recommendations in the face of COVID-19.Research Question: Does exercise at various intensities produce aerosols in significant quantities?Study Design and Methods: In this experimental study, subjects were eight healthy volunteers (six men, two women) who were 20 to 63 years old. The 20-minute test protocol of 5 minutes rest, four 3-minute stages of exercise at 25%, 50%, 75%, and 100% of age-predicted heart rate reserve, and 3 minutes active recovery was performed in a clean, controlled environment. Aerosols were measured by four particle counters that were place to surround the subject.Results: Age averaged 41 ± 14 years. Peak heart rate was 173 ± 17 beat/min (97% predicted); peak maximal oxygen uptake was 33.9 ± 7.5 mL/kg/min; and peak respiratory exchange ratio was 1.22 ± 0.10. Maximal ventilation averaged 120 ± 23 L/min, while cumulative ventilation reached 990 ± 192 L. Concentrations increased exponentially from start to 20 minutes (geometric mean ± geometric SD particles/liter): Fluke >0.3 μm = 66 ± 1.8 → 1605 ± 3.8; 0.3-1.0 μm = 35 ± 2.2 → 1095 ± 4.6; Fluke 1.0-5.0 μm = 21 ± 2.0 → 358 ± 2.3; P-Trak anterior = 637 ± 2.3 → 5148 ± 3.0; P-Trak side = 708 ± 2.7 → 6844 ± 2.7; P-Track back = 519 ± 3.1 → 5853 ± 2.8. All increases were significant at a probability value of <.05. Exercise at or above 50% of predicted heart rate reserve showed statistically significant increases in aerosol concentration.Interpretation: Our data suggest exercise testing is an aerosol-generating procedure and, by extension, other activities that involve exercise intensities at or above 50% of predicted heart rate reserve. Results can guide recommendations for safety of exercise testing and other indoor exercise activities. [ABSTRACT FROM AUTHOR]

Published
2021
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26. Mitigation of Aerosols Generated During Exercise Testing With a Portable High-Efficiency Particulate Air Filter With Fume Hood.

Author

Garzona-Navas, Andrés, Sajgalik, Pavol, Csécs, Ibolya, Askew, J. Wells, Lopez-Jimenez, Francisco, Niven, Alexander S., Johnson, Bruce D., Allison, Thomas G., Garzona-Navas, Andres, Ibolya, Csecs, and Csecs, Ibolya

Abstract

Background: The role of portable high-efficiency particulate air (HEPA) filters for supplemental aerosol mitigation during exercise testing is unknown and might be relevant during COVID-19 pandemic.Research Question: What is the effect of portable HEPA filtering on aerosol concentration during exercise testing and its efficiency in reducing room clearance time in a clinical exercise testing laboratory?Study Design and Methods: Subjects were six healthy volunteers aged 20 to 56 years. In the first experiment, exercise was performed in a small tent with controlled airflow with the use of a stationary cycle, portable HEPA filter with fume hood, and particle counter to document aerosol concentration. Subjects performed a four-stage maximal exercise test that lasted 12 min plus 5 min of pretest quiet breathing and 3 min of active recovery. First, they exercised without mitigation then with portable HEPA filter running. In a separate experiment, room aerosol clearance time was measured in a clinical exercise testing laboratory by filling it with artificially generated aerosols and measuring time to 99.9% aerosol clearance with heating, ventilation, and air conditioning (HVAC) only or HVAC plus portable HEPA filter running.Results: In the exercise experiment, particle concentrations reached 1,722 ± 1,484/L vs 96 ± 124/L (P < .04) for all particles (>0.3 μm), 1,339 ± 1,281/L vs 76 ± 104/L (P < .05) for smaller particles (0.3 to 1.0 μm), and 333 ± 209/L vs 17 ± 19/L (P < .01) for larger particles (1.0 to 5.0 μm) at the end of the protocol in a comparison of mitigation vs portable HEPA filter. Use of a portable HEPA filter in a clinical exercise laboratory clearance experiment reduced aerosol clearance time 47% vs HVAC alone.Interpretation: The portable HEPA filter reduced the concentration of aerosols generated during exercise testing by 96% ± 2% for all particle sizes and reduced aerosol room clearance time in clinical exercise testing laboratories. Portable HEPA filters therefore might be useful in clinical exercise testing laboratories to reduce the risk of COVID-19 transmission. [ABSTRACT FROM AUTHOR]

Published
2021
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27. Low Noise Exhaust Nozzle Technology Development

Author

Majjigi, R. K, Balan, C, Mengle, V, Brausch, J. F, Shin, H, and Askew, J. W

Subjects
Aeronautics (General)
Abstract

NASA and the U.S. aerospace industry have been assessing the economic viability and environmental acceptability of a second-generation supersonic civil transport, or High Speed Civil Transport (HSCT). Development of a propulsion system that satisfies strict airport noise regulations and provides high levels of cruise and transonic performance with adequate takeoff performance, at an acceptable weight, is critical to the success of any HSCT program. The principal objectives were to: 1. Develop a preliminary design of an innovative 2-D exhaust nozzle with the goal of meeting FAR36 Stage III noise levels and providing high levels of cruise performance with a high specific thrust for Mach 2.4 HSCT with a range of 5000 nmi and a payload of 51,900 lbm, 2. Employ advanced acoustic and aerodynamic codes during preliminary design, 3. Develop a comprehensive acoustic and aerodynamic database through scale-model testing of low-noise, high-performance, 2-D nozzle configurations, based on the preliminary design, and 4. Verify acoustic and aerodynamic predictions by means of scale-model testing. The results were: 1. The preliminary design of a 2-D, convergent/divergent suppressor ejector nozzle for a variable-cycle engine powered, Mach 2.4 HSCT was evolved, 2. Noise goals were predicted to be achievable for three takeoff scenarios, and 3. Impact of noise suppression, nozzle aerodynamic performance, and nozzle weight on HSCT takeoff gross weight were assessed.

Published
2005

28. Static Aerodynamic Performance Investigation of a Fluid Shield Nozzle

Author

Balan, C and Askew, J. W

Subjects
Aircraft Design, Testing And Performance
Abstract

In pursuit of an acoustically acceptable, high performance exhaust system capable of meeting Federal Aviation Regulation 36 Stage 3 noise goals for the High Speed Civil Transport application, General Electric Aircraft Engines conducted a design study to incorporate a fluid shield into a 36-chute suppressor exhaust-nozzle system. After a full scale preliminary mechanical design of the resulting fluid shield exhaust system, scale model aerodynamic performance tests and acoustic tests were conducted to establish both aerodynamic performance and acoustic characteristics. Data are presented as thrust coefficients, discharge coefficients, chute-base pressure drags, and plug static pressure distributions.

Published
2005

30. The Authors Reply

Author

ASKEW, J. R., BEARDWOOD, J. E., and NEWBY, D.

Published
1969

34. Temporal Trends of Single-Photon Emission Computed Tomography Myocardial Perfusion Imaging in Patients With Coronary Artery Disease: A 22-Year Experience From a Tertiary Academic Medical Center.

Author

Jouni, Hayan, Askew, J. Wells, Crusan, Daniel J., Miller, Todd D., and Gibbons, Raymond J.

Abstract

Background—There has been a gradual decline in the prevalence of abnormal stress single-photon emission computed tomography (SPECT) myocardial perfusion imaging studies among patients without history of coronary artery disease (CAD). The trends of SPECT studies among patients with known CAD have not been evaluated previously. Methods and Results—We assessed the Mayo Clinic nuclear cardiology database for all stress SPECT tests performed between January 1991 and December 2012 in patients with history of CAD defined as having previous myocardial infarction, percutaneous coronary intervention, and coronary artery bypass grafting. The study cohort was divided into 5 time periods: 1991 to 1995, 1996 to 2000, 2001 to 2005, 2006 to 2010, and 2011 to 2012. There were 19 373 patients with a history of CAD who underwent SPECT between 1991 and 2012 (mean age, 66.2±10.9 years; 75.4% men). Annual utilization of SPECT in these patients increased from an average of 495 tests per year in 1991 to 1995 to 1425 in 2003 and then decreased to 552 tests in 2012 without evidence for substitution with other stress modalities. Asymptomatic patients initially increased until 2006 and then decreased. Patients with typical angina decreased, whereas patients with dyspnea and atypical angina increased. High-risk SPECT tests significantly decreased, and the percentage of low-risk SPECT tests increased despite decreased SPECT utilization between 2003 and 2012. Almost 80% of all tests performed in 2012 had a low-risk summed stress score compared with 29% in 1991 (P<0.001). Conclusions—In Mayo Clinic, Rochester, annual SPECT utilization in patients with previous CAD increased between 1992 and 2003, but then decreased after 2003. High-risk SPECT tests declined, whereas low-risk tests increased markedly. Our results suggest that among patients with a history of CAD, SPECT was being increasingly utilized in patients with milder CAD. This trend parallels reduced utilization of other stress modalities, coronary angiography, reduced smoking, and greater utilization of optimal medical therapy for prevention and treatment of CAD. [ABSTRACT FROM AUTHOR]

Published
2017
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35. Abnormal stress echocardiography findings in cardiac amyloidosis.

Author

Ong, Kevin C., Wells Askew, J., Dispenzieri, Angela, Maleszewski, Joseph J., Klarich, Kyle W., Anavekar, Nandan S., Mulvagh, Sharon L., and Grogan, Martha

Subjects
*STRESS echocardiography, *CARDIAC amyloidosis, *IMMUNOGLOBULINS, *TRANSTHYRETIN, *AMYLOIDOSIS diagnosis
Abstract

Background: Cardiac involvement in immunoglobulin light chain (amyloid light chain, AL) amyloidosis is characterized by myocardial interstitial deposition but can also cause obstructive deposits in the coronary microvasculature. Methods: We retrospectively identified 20 patients who underwent stress echocardiography within 1 year prior to the histologic diagnosis of AL amyloidosis. Only patients with cardiac amyloidosis and no known obstructive coronary disease were included. Results: Stress echocardiograms (13 exercise; 7 dobutamine) were performed for evaluation of dyspnea and/or chest pain. Stress-induced wall motion abnormalities (WMAs) occurred in 11 patients (55%), 4 of whom had normal left ventricular wall thickness. Coronary angiogram was performed in 9 of 11 patients and demonstrated no or mild epicardial coronary artery disease. Seven (54%) patients had an abnormal exercise blood pressure which occurred with similar likelihood between those with and without stress-induced WMAs. Conclusions: Stress-induced WMAs and abnormal exercise blood pressure may occur in patients with cardiac AL amyloidosis despite the absence of significant epicardial coronary artery disease. This finding should raise the possibility of cardiac amyloidosis even in the absence of significant myocardial thickening. [ABSTRACT FROM PUBLISHER]

Published
2016
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36. Temporal trends of single-photon emission computed tomography myocardial perfusion imaging in patients without prior coronary artery disease: A 22-year experience at a tertiary academic medical center.

Author

Jouni, Hayan, Askew, J. Wells, Crusan, Daniel J., Miller, Todd D., and Gibbons, Raymond J.

Abstract

Background: Between 1990 and 2006, there was a large national increase in utilization of single-photon emission computed tomography myocardial perfusion imaging (SPECT) for assessment of coronary artery disease (CAD). We aim to examine the trends of SPECT test results and patients' characteristics at Mayo Clinic Rochester.Methods: Using the Mayo Clinic nuclear cardiology database, we examined all SPECT tests performed between January 1, 1991, and December 31, 2012, in patients without prior CAD. The study cohort was divided into 5 time periods: 1991-1995, 1996-2000, 2001-2005, 2006-2010, and 2011-2012.Results: There were 35,894 eligible SPECT tests (mean age 62.5 ± 12 years, 54% men). Annual utilization of SPECT increased significantly in 1992-2002 but then decreased without evidence of test substitution with stress echocardiography. There were modest changes in CAD risk factors over time. Testing of asymptomatic patients doubled (21.9% in 1991-1995 to 40% in 2006-2010) but later decreased to 33.6% in 2011-2012. Tests on patients with typical angina decreased dramatically (18.3% in 1991-1995 to 6.7% in 2011-2012). Summed stress score, summed difference score, and high-risk SPECT tests all decreased over time in both symptomatic and asymptomatic patients regardless of stress modality (exercise vs pharmacologic).Conclusions: In Mayo Clinic Rochester, annual SPECT utilization in patients without prior CAD increased in 1992-2002 but then decreased. Despite similar CAD risk factors and decreased utilization after 2003, more tests were low risk; summed stress score, summed difference score, and high-risk tests all decreased. Our findings confirm previous observations that SPECT was increasingly used in patients with a lower prevalence of CAD. [ABSTRACT FROM AUTHOR]

Published
2016
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41. Centaur engine gimbal friction characteristics under simulated thrust load

Author

Askew, J. W

Subjects
Launch Vehicles And Space Vehicles
Abstract

An investigation was performed to determine the friction characteristics of the engine gimbal system of the Centaur upper stage rocket. Because the Centaur requires low-gain autopilots in order to meet all stability requirements for some configurations, control performance (response to transients and limit-cycle amplitudes) depends highly on these friction characteristics. Forces required to rotate the Centaur engine gimbal system were measured under a simulated thrust load of 66,723 N (15,000 lb) and in an altitude/thermal environment. A series of tests was performed at three test conditions; ambient temperature and pressure, ambient temperature and vacuum, and cryogenic temperature and vacuum. Gimbal rotation was controlled, and tests were performed in which rotation amplitude and frequency were varied by using triangular and sinusoidal waveforms. Test data revealed an elastic characteristic of the gimbal, independent of the input signal, which was evident prior to true gimbal sliding. The torque required to initiate gimbal sliding was found to decrease when both pressure and temperature decreased. Results from the low amplitude and low frequency data are currently being used in mathematically modeling the gimbal friction characteristics for Centaur autopilot performance studies.

Published
1986

42. Low Yield of Stress Imaging in a Population-Based Study of Asymptomatic Patients After Percutaneous Coronary Intervention.

Author

Peterson, Tyler, Askew, J. Wells, Bell, Malcolm, Crusan, Daniel, Hodge, David, and Gibbons, Raymond J.

Abstract

Little is known about the clinical value of stress imaging studies in asymptomatic patients after percutaneous coronary intervention (PCI).Residents of Olmsted County, MN, who underwent PCI were followed up for the occurrence of stress imaging (stress nuclear or stress echocardiography), coronary angiography, or coronary artery bypass grafting (without angiography) as initial procedures after PCI. Patients whose first follow-up procedure was a stress imaging test were evaluated for their symptom status at the time of the study and whether they underwent angiography or revascularization (PCI or coronary artery bypass grafting) within 90 days. Of 1848 patients who underwent PCI during the study period, 710 (38%) had stress imaging as their initial procedure after PCI, and 241 (13% of the entire cohort) were asymptomatic at the time of testing. The majority (86%) of these 241 patients underwent PCI for acute myocardial infarction or unstable angina. Within 90 days of stress imaging, 16 of the 241 asymptomatic patients underwent angiography, and 2 patients were revascularized. Stratified by timing after PCI, none of 138 asymptomatic patients tested within 2 years of PCI underwent revascularization. Two of 103 asymptomatic patients tested after 2 years from PCI underwent revascularization. Compared with patients who were asymptomatic at the time of stress imaging, patients who did not undergo any follow-up procedures (stress imaging, angiography, or coronary artery bypass grafting) after the index PCI were older, were more likely to have comorbidities, and had significantly greater all-cause mortality (P<0.001).In a population-based sample of patients undergoing PCI primarily for acute coronary syndromes, 1 in 8 had subsequent stress imaging when they were asymptomatic. These stress imaging tests resulted in further revascularization in <1% of patients. The low rate of downstream revascularization suggests that stress imaging in asymptomatic patients after PCI has low value. [ABSTRACT FROM AUTHOR]

Published
2014
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43. Evaluation of Molecular Breast Imaging in Women Undergoing Myocardial Perfusion Imaging with Tc-99m Sestamibi.

Author

Hruska, Carrie B., Rhodes, Deborah J., Collins, Douglas A., Tortorelli, Cindy L., Askew, J. Wells, and O'Connor, Michael K.

Subjects
BREAST tumor diagnosis, CLINICAL trials, CONFIDENCE intervals, DIAGNOSTIC errors, DIAGNOSTIC imaging, EPIDEMIOLOGY, MOLECULAR diagnosis, NEEDLE biopsy, PERFUSION, RADIONUCLIDE imaging, RESEARCH, RESEARCH funding, DATA analysis, EARLY detection of cancer
Abstract

Background: Our objective was to explore the potential benefits of molecular breast imaging (MBI) as a screening technique in women undergoing stress myocardial perfusion studies. Methods: MBI was offered to women receiving Tc-99m sestamibi injection for myocardial perfusion stress testing. During the required waiting period after stress isotope injection, MBI was performed using a dedicated breast imaging gamma camera system. MBI examinations were interpreted by breast radiologists, with review of a recent mammogram in cases with positive MBI. Results: Of 322 women enrolled, 313 completed MBI, comprising 5 with known breast cancer, 2 with known high-risk benign breast lesions, and 306 who were asymptomatic for breast disease with a recent negative mammogram. Analysis was limited to the 306 patients with no known breast disease. MBI was positive in 22 of 306, giving a recall rate of 7.2% (95% confidence interval [CI] 4.8-10.6]. MBI detected 4 new cancers, resulting in a supplemental diagnostic yield of 13.1/1000 women screened (95% CI 5.1-33.2). The number of cancers diagnosed per abnormal MBI examinations (PPV1) was 18% (4 of 22) (95% CI 7.3-38.5), and the number diagnosed per MBI-prompted biopsies (PPV3) was 44% (4 of 9) (95% CI 18.9-73.3). Conclusions: The addition of MBI to clinically indicated stress myocardial perfusion imaging studies in women results in a high diagnostic yield of newly detected breast cancers while generating a low rate of additional unnecessary workup. [ABSTRACT FROM AUTHOR]

Published
2012
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44. The Timing and Impact of Follow-Up Studies After Normal Stress Single-Photon Emission Computed Tomography Sestamibi Studies.

Author

Carryer, Damita Jo, Askew, J. Wells, Hodge, David O., Miller, Todd D., and Gibbons, Raymond J.

Subjects
CARDIOGRAPHIC tomography, PHOTON emission, MYOCARDIAL infarction, PERFUSION, TOMOGRAPHY, CARDIAC imaging
Abstract

The article presents a study that investigated the prevalence and timing of routine follow-up single-photon emission computed tomography (SPECT) studies after a normal stress SPECT scan compared with the patient's warranty period, or the time to 1% risk of death or myocardial infarction. Researchers found that retesting is being performed at a relatively low rate among patients at Mayo Clinic Rochester who had normal stress SPECT myocardial perfusion imaging (MPI) in 2002 and no history of coronary artery disease (CAD).

Published
2010
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45. Takotsubo Cardiomyopathy: A Unique Cardiomyopathy With Variable Ventricular Morphology.

Author

Hurst, R. Todd, Prasad, Abhiram, Askew, J. Wells, Sengupta, Partho P., and Tajik, A. Jamil

Subjects
CARDIOMYOPATHIES, CARDIOVASCULAR disease diagnosis, PATHOLOGICAL physiology, CATECHOLAMINES, HEART ventricle abnormalities, HEART disease prognosis, CORONARY arteries
Abstract

Takotsubo cardiomyopathy is an important differential diagnosis of acute coronary syndrome. It is characterized by normal (or near-normal) coronary arteries, regional wall motion abnormalities that extend beyond a single coronary vascular bed, and often, a precipitating stressor. Variants of the classical left ventricular apical ballooning, including mid- or basal left ventricular wall motion abnormalities, are increasingly recognized. Takotsubo cardiomyopathy is not rare, and heightened awareness of this unique cardiomyopathy likely will lead to a higher reported incidence. Diagnosis of takotsubo cardiomyopathy has important implications for clinical management at presentation and afterward. The long-term prognosis is generally favorable; however, a small subset has potentially life-threatening complications during the initial presentation. The pathophysiologic mechanism is unknown, but catecholamine excess likely has a central role. [Copyright &y& Elsevier]

Published
2010
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48. Women living with men who use Viagra: an exploratory study.

Author

Askew J and Davey M

Abstract

Since the launch of Viagra, there have been few studies on the perspective of the female partner. Through a multiple case study approach drawing from phenomenology and the constant comparative method of analysis, this qualitative exploratory study examines the stories of four women living with a spouse who is currently taking Viagra. Findings highlight the need for a more holistic approach to treating erectile dysfunction that supports both partners within the couple relationship. It is also suggested that greater attention should be given to the relationship and to the sexual needs of women. [ABSTRACT FROM AUTHOR]

Published
2004
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50. Characterisation of oxidative injury to an intestinal cell line (HT-29) by hydrogen peroxide.

Author

Watson, A J, Askew, J N, and Sandle, G I

Abstract

Reactive oxygen metabolites have been implicated in causing epithelial cell injury in colonic inflammation. A model of oxidant injury in intestinal epithelial cells has been developed in which HT-29-18-C1 cells are injured with graded concentrations of hydrogen peroxide and characterised by the MTT test. The MTT test was validated as a cytotoxicity assay and has a similar sensitivity to hydrogen peroxide induced injury as the assay of intracellular adenosine triphosphate. Exposure to a range of hydrogen peroxide concentrations (0.05-20 mM) for varying duration (5-120 min) showed that injury was dependent on time and concentration. The median lethal dose (LD50) for one hour exposure to hydrogen peroxide was approximately 0.1 mM. Injury from hydrogen peroxide was only partially reversible as determined by the MTT test and assay of cellular proliferation by crystal violet staining. There was an exponential loss of hydrogen peroxide when incubated with HT-29-18-C1 cells (t1/2 35 min). Experiments with 0.5 mg/ml aminotriazole and 0.5-2 mM buthionine sulphoximine suggested hydrogen peroxide breakdown was predominantly caused by catalase rather than glutathione peroxidase. Injury resulting from 1 mM hydrogen peroxide could be reduced by either coincubation of cells with 1,10-phenanthroline, an Fe2+ chelator, or preincubation with deferoxamine, and Fe3+ chelator, suggesting the participation of Fe2+ and Fe3+ in hydrogen peroxide induced injury. In conclusion, hydrogen peroxide induces injury in HT-29-18-C1 cells both directly and by generation of the hydroxyl radical. [ABSTRACT FROM PUBLISHER]

Published
1994

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