12 results on '"Anne Agur"'
Search Results
2. THE ROLE OF WOMEN IN THE TEACHING-RESEARCH OF ANATOMY IN MEDICINE IN CANADA
- Author
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Claudia Krebs and Anne Agur
- Subjects
Anatomy ,educación médica ,Medicine ,Pathology ,RB1-214 - Abstract
None
- Published
- 2023
- Full Text
- View/download PDF
3. Gross and applied anatomy pedagogical approaches in occupational therapy education: protocol for a scoping review
- Author
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Emily S Ho, Anne Agur, Andrea Duncan, Erica Dove, Kelly Hennessy, Athena Kirou-Mauro, and Lorna Aitkens
- Subjects
Medicine - Published
- 2022
- Full Text
- View/download PDF
4. DR. KEITH LEON MOORE, BA, MSC, PHD, HON. D.SC (OSU), HON. D.SC (WU) FIAC, FRSM, FAAA
- Author
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Anne Agur and Arthur (Art) Dalley
- Subjects
Medicine ,Pathology ,RB1-214 - Published
- 2020
- Full Text
- View/download PDF
5. Automatic three-dimensional reconstruction of fascicles in peripheral nerves from histological images.
- Author
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Daniel Tovbis, Anne Agur, Jeremy P M Mogk, and José Zariffa
- Subjects
Medicine ,Science - Abstract
Computational studies can be used to support the development of peripheral nerve interfaces, but currently use simplified models of nerve anatomy, which may impact the applicability of simulation results. To better quantify and model neural anatomy across the population, we have developed an algorithm to automatically reconstruct accurate peripheral nerve models from histological cross-sections. We acquired serial median nerve cross-sections from human cadaveric samples, staining one set with hematoxylin and eosin (H&E) and the other using immunohistochemistry (IHC) with anti-neurofilament antibody. We developed a four-step processing pipeline involving registration, fascicle detection, segmentation, and reconstruction. We compared the output of each step to manual ground truths, and additionally compared the final models to commonly used extrusions, via intersection-over-union (IOU). Fascicle detection and segmentation required the use of a neural network and active contours in H&E-stained images, but only simple image processing methods for IHC-stained images. Reconstruction achieved an IOU of 0.42±0.07 for H&E and 0.37±0.16 for IHC images, with errors partially attributable to global misalignment at the registration step, rather than poor reconstruction. This work provides a quantitative baseline for fully automatic construction of peripheral nerve models. Our models provided fascicular shape and branching information that would be lost via extrusion.
- Published
- 2020
- Full Text
- View/download PDF
6. Micro-biomechanics of the Kebara 2 hyoid and its implications for speech in Neanderthals.
- Author
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Ruggero D'Anastasio, Stephen Wroe, Claudio Tuniz, Lucia Mancini, Deneb T Cesana, Diego Dreossi, Mayoorendra Ravichandiran, Marie Attard, William C H Parr, Anne Agur, and Luigi Capasso
- Subjects
Medicine ,Science - Abstract
The description of a Neanderthal hyoid from Kebara Cave (Israel) in 1989 fuelled scientific debate on the evolution of speech and complex language. Gross anatomy of the Kebara 2 hyoid differs little from that of modern humans. However, whether Homo neanderthalensis could use speech or complex language remains controversial. Similarity in overall shape does not necessarily demonstrate that the Kebara 2 hyoid was used in the same way as that of Homo sapiens. The mechanical performance of whole bones is partly controlled by internal trabecular geometries, regulated by bone-remodelling in response to the forces applied. Here we show that the Neanderthal and modern human hyoids also present very similar internal architectures and micro-biomechanical behaviours. Our study incorporates detailed analysis of histology, meticulous reconstruction of musculature, and computational biomechanical analysis with models incorporating internal micro-geometry. Because internal architecture reflects the loadings to which a bone is routinely subjected, our findings are consistent with a capacity for speech in the Neanderthals.
- Published
- 2013
- Full Text
- View/download PDF
7. Three-dimensional architecture of the great toe muscles: functional implications in hallux valgus
- Author
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Valera Castanov, Maxine D. Vienneau, Diane Tyczynski, S. Ahmed Hassan, Takamitsu Arakawa, and Anne Agur
- Subjects
Orthodontics ,Valgus ,Three dimensional architecture ,biology ,Computer science ,Health Care Sciences and Services ,fiber bundle lenght,great toe,hallux valgus,muscle architecture,PCSA,pennation angle,volume ,Anatomy ,Sağlık Bilimleri ve Hizmetleri ,biology.organism_classification - Abstract
Objectives: Imbalance of great toe musculature has been identified as a factor in the development of hallux valgus. The musculoaponeurotic architecture, an important determinant of function, has not been investigated volumetrically in the great toe musculature. The purpose of this study was to reconstruct the abductor halluces (ABDH), adductor halluces (ADH), flexor hallucis brevis medial (FHBM) and lateral (FHBL) heads volumetrically and to quantify and compare their architectural parameters and functional characteristics. Methods: Ten formalin-embalmed specimens were dissected, digitized and modelled (Autodesk Maya®). Fiber bundle length (FBL) and physiological cross-sectional area (PCSA) of the muscles were compared using descriptive and parametric statistics. Results: The spatial arrangement of aponeuroses (AP) / fiber bundles (FB) and architectural parameters varied throughout the volume of each muscle. The PCSA of the medial (ABDH/FHBM) and lateral (ADH/FHBL) musculature was similar; however, the medial musculature had significantly greater mean FBL. Conclusion: Each muscle had varying AP/FB arrangement. The similar PCSA of the medial and lateral musculature suggests that their relative force generating capabilities are balanced in asymptomatic individuals.
- Published
- 2020
8. Depicting surgical anatomy of the porta hepatis in living donor liver transplantation
- Author
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Paul Kelly, Jodie Jenkinson, Anne Agur, Ian D. McGilvray, Joy Qu, Paul D. Greig, A. Fung, and Gordon Tait
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0301 basic medicine ,Porta hepatis ,Surgical team ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Case Report on Liver Surgery ,Visualization ,Surgery ,Medical illustration ,03 medical and health sciences ,medicine.anatomical_structure ,medicine ,Gross anatomy ,030101 anatomy & morphology ,Radiology ,Hepatectomy ,Living donor liver transplantation ,business ,Computer animation ,ComputingMethodologies_COMPUTERGRAPHICS - Abstract
Visualizing the complex anatomy of vascular and biliary structures of the liver on a case-by-case basis has been challenging. A living donor liver transplant (LDLT) right hepatectomy case, with focus on the porta hepatis, was used to demonstrate an innovative method to visualize anatomy with the purpose of refining preoperative planning and teaching of complex surgical procedures. The production of an animation-enhanced video consisted of many stages including the integration of pre-surgical planning; case-specific footage and 3D models of the liver and associated vasculature, reconstructed from contrast-enhanced CTs. Reconstructions of the biliary system were modeled from intraoperative cholangiograms. The distribution of the donor portal veins, hepatic arteries and bile ducts was defined from the porta hepatis intrahepatically to the point of surgical division. Each step of the surgery was enhanced with 3D animation to provide sequential and seamless visualization from pre-surgical planning to outcome. Use of visualization techniques such as transparency and overlays allows viewers not only to see the operative field, but also the origin and course of segmental branches and their spatial relationships. This novel educational approach enables integrating case-based operative footage with advanced editing techniques for visualizing not only the surgical procedure, but also complex anatomy such as vascular and biliary structures. The surgical team has found this approach to be beneficial for preoperative planning and clinical teaching, especially for complex cases. Each animation-enhanced video case is posted to the open-access Toronto Video Atlas of Surgery (TVASurg), an education resource with a global clinical and patient user base. The novel educational system described in this paper enables integrating operative footage with 3D animation and cinematic editing techniques for seamless sequential organization from pre-surgical planning to outcome.
- Published
- 2017
9. Sacro-Iliac Joint Sensory Block and Radiofrequency Ablation: Assessment of Bony Landmarks Relevant for Image-Guided Procedures
- Author
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Anne Agur, Eldon Loh, Robert S. Burnham, Shannon L. Roberts, and Trevor J. G. Robinson
- Subjects
Male ,0301 basic medicine ,Sacrum ,Lateral sacral crest ,Article Subject ,Sacro-iliac joint ,Radiofrequency ablation ,medicine.medical_treatment ,lcsh:Medicine ,Sensory system ,Sensitivity and Specificity ,General Biochemistry, Genetics and Molecular Biology ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Cadaver ,law ,Humans ,Medicine ,Sacroiliac joint ,General Immunology and Microbiology ,business.industry ,lcsh:R ,Reproducibility of Results ,Nerve Block ,Sacroiliac Joint ,General Medicine ,Anatomy ,Combined Modality Therapy ,Spinal Nerves ,Treatment Outcome ,medicine.anatomical_structure ,Surgery, Computer-Assisted ,Catheter Ablation ,Nerve block ,Female ,030101 anatomy & morphology ,Anatomic Landmarks ,business ,030217 neurology & neurosurgery ,Research Article - Abstract
Image-guided sensory block and radiofrequency ablation of the nerves innervating the sacro-iliac joint require readily identifiable bony landmarks for accurate needle/electrode placement. Understanding the relative locations of the transverse sacral tubercles along the lateral sacral crest is important for ultrasound guidance, as they demarcate the position of the posterior sacral network (S1–S3 ± L5/S4) innervating the posterior sacro-iliac joint. No studies were found that investigated the spatial relationships of these bony landmarks. The purpose of this study was to visualize and quantify the interrelationships of the transverse sacral tubercles and posterior sacral foramina to inform image-guided block and radiofrequency ablation of the sacro-iliac joint. The posterior and lateral surfaces of 30 dry sacra (15 M/15 F) were digitized and modeled in 3D and the distances between bony landmarks quantified. The relationships of bony landmarks (S1–S4) were not uniform. The mean intertubercular and interforaminal distances decreased from S1 to S4, whereas the distance from the lateral margin of the posterior sacral foramina to the transverse sacral tubercles increased from S1 to S3. The mean intertubercular distance from S1 to S3 was significantly (p<0.05) larger in males. The interrelationships of the sacral bony landmarks should be taken into consideration when estimating the site and length of an image-guided strip lesion targeting the posterior sacral network.
- Published
- 2016
10. Quantification and comparison of neurosurgical approaches in the preclinical setting: literature review
- Author
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Eduardo Fernandez, Ivan Radovanovic, Jimmy Qiu, Gelareh Zadeh, Mayoorendra Ravichandiran, Anne Agur, Walter Kucharczyk, Marco Maria Fontanella, Fred Gentili, and Francesco Doglietto
- Subjects
medicine.medical_specialty ,Anastomosis ,Comparison ,Neurosurgical Procedures ,Imaging ,03 medical and health sciences ,Outcome Assessment (Health Care) ,Imaging, Three-Dimensional ,0302 clinical medicine ,Quantification ,Surgical ,Outcome Assessment, Health Care ,medicine ,Humans ,Surgical Wound Infection ,Medical physics ,Research method ,Surgical approach ,Anatomical studies ,Neurosurgical approach ,Anastomosis, Surgical ,Surgical Procedures, Operative ,Surgical Procedures ,business.industry ,General Medicine ,Operative ,Surgery ,Visualization ,030220 oncology & carcinogenesis ,Three-Dimensional ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
There is a growing awareness of the need for evidence-based surgery and of the issues that are specific to research in surgery. Well-conducted anatomical studies can represent the first, preclinical step for evidence-based surgical innovation and evaluation. In the last two decades, various reports have quantified and compared neurosurgical approaches in the anatomy laboratory using different methods and technology. The aim of this study was to critically review these papers. A PubMed and Scopus search was performed to select articles that quantified and compared different neurosurgical approaches in the preclinical setting. The basic characteristics that anatomically define a surgical approach were defined. Each study was analyzed for measured features and quantification method and technique. Ninety-nine papers, published from 1990 to 2013, were included in this review. A heterogeneous use of terms to define the features of a surgical approach was evident. Different methods to study these features have been reported; they are generally based on quantification of distances, angles, and areas. Measuring tools have evolved from the simple ruler to frameless stereotactic devices. The reported methods have each specific advantages and limits; a common limitation is the lack of 3D visualization and surgical volume quantification. There is a need for a uniform nomenclature in anatomical studies. Frameless stereotactic devices provide a powerful tool for anatomical studies. Volume quantification and 3D visualization of the surgical approach is not provided with most available methods.
- Published
- 2016
11. The orbitozygomatic approach
- Author
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Anne Agur, Michael D. Cusimano, Wouter R. van Furth, Nicholas Woolridge, Amsterdam Neuroscience, and Neurosurgery
- Subjects
Brain Diseases ,Zygoma ,medicine.medical_specialty ,Surgical approach ,business.industry ,Objective (goal) ,medicine.medical_treatment ,Neurosurgery ,Pterional approach ,Mastery learning ,Cranial base surgery ,Surgery ,Imaging, Three-Dimensional ,Surgical anatomy ,Humans ,Medicine ,Medical physics ,Neurology (clinical) ,business ,Orbit ,Craniotomy ,Computer animation - Abstract
OBJECTIVE:The orbitozygomatic approach is a modification and extension of the pterional craniotomy to gain a wider exposure of structures at a cranial base. To simplify the understanding and performance of the approach, we developed a teaching video that follows a systematic approach to the surgical anatomy and technique.METHODS:The authors have incorporated three-dimensional (3D) renderings into the descriptions of the surgical technique and contemporary computer animation is used to demonstrate surgical details and nuances of the procedure.RESULTS:A teaching video was compiled, and it was well received by neurosurgical residents in Europe and Canada.CONCLUSION:With mastery in the surgical laboratory and with guided supervision, the approach can be routinely applied without adding morbidity to a variety of pathologies such as aneurysms and tumors.
- Published
- 2006
12. Micro-Biomechanics of the Kebara 2 Hyoid and Its Implications for Speech in Neanderthals
- Author
-
Marie R. G. Attard, Luigi Capasso, Claudio Tuniz, D.T. Cesana, Diego Dreossi, Ruggero D'Anastasio, Mayoorendra Ravichandiran, Lucia Mancini, Anne Agur, Stephen Wroe, and William C. H. Parr
- Subjects
Neanderthal ,Anatomy and Physiology ,Science ,Vertebrate Paleontology ,Biophysics ,Social and Behavioral Sciences ,Biomechanical Phenomena ,biology.animal ,Speech ,Animals ,Humans ,Scientific debate ,Biomechanics ,Biology ,Musculoskeletal System ,Neanderthals ,Cognitive science ,Multidisciplinary ,biology ,Homo neanderthalensis ,Hyoid bone ,Bone and Joint Mechanics ,Hyoid Bone ,Paleontology ,Linguistics ,Anatomy ,Homo sapiens ,Anthropology ,Earth Sciences ,Medicine ,Gross anatomy ,Physical Anthropology ,Paleobiology ,Psychology ,Research Article - Abstract
The description of a Neanderthal hyoid from Kebara Cave (Israel) in 1989 fuelled scientific debate on the evolution of speech and complex language. Gross anatomy of the Kebara 2 hyoid differs little from that of modern humans. However, whether Homo neanderthalensis could use speech or complex language remains controversial. Similarity in overall shape does not necessarily demonstrate that the Kebara 2 hyoid was used in the same way as that of Homo sapiens. The mechanical performance of whole bones is partly controlled by internal trabecular geometries, regulated by bone-remodelling in response to the forces applied. Here we show that the Neanderthal and modern human hyoids also present very similar internal architectures and micro-biomechanical behaviours. Our study incorporates detailed analysis of histology, meticulous reconstruction of musculature, and computational biomechanical analysis with models incorporating internal micro-geometry. Because internal architecture reflects the loadings to which a bone is routinely subjected, our findings are consistent with a capacity for speech in the Neanderthals.
- Published
- 2013
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