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We develop a series of N-body data challenges, functional to the final analysis of the extended Baryon Oscillation Spectroscopic Survey (eBOSS) Data Release 16 (DR16) galaxy sample. The challenges are primarily based on high-fidelity catalogues constructed from the Outer Rim simulation - a large box size realization (3h-1Gpc) characterized by an unprecedented combination of volume and mass resolution, down to 1.85 × 109h-1M. We generate synthetic galaxy mocks by populating Outer Rim haloes with a variety of halo occupation distribution (HOD) schemes of increasing complexity, spanning different redshift intervals. We then assess the performance of three complementary redshift space distortion (RSD) models in configuration and Fourier space, adopted for the analysis of the complete DR16 eBOSS sample of Luminous Red Galaxies (LRGs). We find all the methods mutually consistent, with comparable systematic errors on the Alcock-Paczynski parameters and the growth of structure, and robust to different HOD prescriptions - thus validating the robustness of the models and the pipelines used for the baryon acoustic oscillation (BAO) and full shape clustering analysis. In particular, all the techniques are able to recover α and α to within $0.9{{\ \rm per\ cent}}$, and fσ8 to within $1.5{{\ \rm per\ cent}}$. As a by-product of our work, we are also able to gain interesting insights on the galaxy-halo connection. Our study is relevant for the final eBOSS DR16 'consensus cosmology', as the systematic error budget is informed by testing the results of analyses against these high-resolution mocks. In addition, it is also useful for future large-volume surveys, since similar mock-making techniques and systematic corrections can be readily extended to model for instance the Dark Energy Spectroscopic Instrument (DESI) galaxy sample., GR, PDC, and JM acknowledge support from the National Research Foundation of Korea (NRF) through Grants No. 2017R1E1A1A01077508 and No. 2020R1A2C1005655 funded by the Korean Ministry of Education, Science and Technology (MoEST), and from the faculty research fund of Sejong University. GR was on sabbatical leave in 2020, when this research was completed. Some numerical work performed in this paper was carried out using the Korea Institute of Science and Technology Information (KISTI) supercomputing infrastructure under allocations KSC-2018-G3-0008 and KSC-2018-T1-0061, and with computing resources at Sejong University (Xeon Silver 4114 master node and Xeon Gold 6126 computing node architecture). HGM acknowledges support from la Caixa Foundation (ID 100010434) which code LCF/BQ/PI18/11630024. RP, SdlT, and SE acknowledge support from the eBOSS ANR grant (under contract ANR-16-CE31-0021) and the OCEVU LABEX (Grant No. ANR-11-LABX-0060) of the French National Research Agency.

The quantum measurement problem can be regarded as the tension between the two alternative dynamics prescribed by quantum mechanics: the unitary evolution of the wave function and the state-update rule (or "collapse") at the instant a measurement takes place. The notorious Wigner's friend gedankenexperiment constitutes the paradoxical scenario in which different observers (one of whom is observed by the other) describe one and the same interaction differently, one --the Friend-- via state-update and the other --Wigner-- unitarily. This can lead to Wigner and his friend assigning different probabilities to the outcome of the same subsequent measurement. In this paper, we apply the Page-Wootters mechanism (PWM) as a timeless description of Wigner's friend-like scenarios. We show that the standard rules to assign two-time conditional probabilities within the PWM need to be modified to deal with the Wigner's friend gedankenexperiment. We identify three main definitions of such modified rules to assign two-time conditional probabilities, all of which reduce to standard quantum theory for non-Wigner's friend scenarios. However, when applied to the Wigner's friend setup each rule assigns different conditional probabilities, potentially resolving the probability-assignment paradox in a different manner. Moreover, one rule imposes strict limits on when a joint probability distribution for the measurement outcomes of Wigner and his Friend is well-defined, which single out those cases where Wigner's measurement does not disturb the Friend's memory and such a probability has an operational meaning in terms of collectible statistics. Interestingly, the same limits guarantee that said measurement outcomes fulfill the consistency condition of the consistent histories framework., 12 pages (plus appendices), 2 figures. Accepted for publication in Quantum

This article generalizes the conditional probability interpretation of time in which time evolution is realized through entanglement between a clock and a system of interest. This formalism is based upon conditioning a solution to the Wheeler-DeWitt equation on a subsystem of the Universe, serving as a clock, being in a state corresponding to a time $t$. Doing so assigns a conditional state to the rest of the Universe $|\psi_S(t)\rangle$, referred to as the system. We demonstrate that when the total Hamiltonian appearing in the Wheeler-DeWitt equation contains an interaction term coupling the clock and system, the conditional state $|\psi_S(t)\rangle$ satisfies a time-nonlocal Schr\"{o}dinger equation in which the system Hamiltonian is replaced with a self-adjoint integral operator. This time-nonlocal Schr\"{o}dinger equation is solved perturbatively and three examples of clock-system interactions are examined. One example considered supposes that the clock and system interact via Newtonian gravity, which leads to the system's Hamiltonian developing corrections on the order of $G/c^4$ and inversely proportional to the distance between the clock and system., Comment: Two new examples of clock-system interactions have been added and a few points clarified. Comments welcome

The epilepsies affect around 65 million people worldwide and have a substantial missing heritability component. We report a genome-wide mega-analysis involving 15,212 individuals with epilepsy and 29,677 controls, which reveals 16 genome-wide significant loci, of which 11 are novel. Using various prioritization criteria, we pinpoint the 21 most likely epilepsy genes at these loci, with the majority in genetic generalized epilepsies. These genes have diverse biological functions, including coding for ion-channel subunits, transcription factors and a vitamin-B6 metabolism enzyme. Converging evidence shows that the common variants associated with epilepsy play a role in epigenetic regulation of gene expression in the brain. The results show an enrichment for monogenic epilepsy genes as well as known targets of antiepileptic drugs. Using SNP-based heritability analyses we disentangle both the unique and overlapping genetic basis to seven different epilepsy subtypes. Together, these findings provide leads for epilepsy therapies based on underlying pathophysiology., SCOPUS: ar.j, info:eu-repo/semantics/published

We implement the entanglement harvesting protocol, in which two Unruh-DeWitt detectors become entangled through local interactions with a quantum field, for the first time in the vicinity of a black hole. Our study, focusing on the BTZ black hole, reveals that black holes inhibit entanglement harvesting. The entanglement harvested rapidly falls to zero when two detectors with fixed proper separation approach the horizon. This effect is a combination of black hole radiation and gravitational red shift, both generic properties of horizons, suggesting it is a general result for black holes., 6 pages, 3 figures

We study how an arbitrary Gaussian state of two localized wave packets, prepared in an inertial frame of reference, is described by a pair of uniformly accelerated observers. We explicitly compute the resulting state for arbitrarily chosen proper accelerations of the observers and independently tuned distance between them. To do so, we introduce a generalized Rindler frame of reference and analytically derive the corresponding state transformation as a Gaussian channel. Our approach provides several new insights into the phenomenon of vacuum entanglement such as the highly non-trivial effect of spatial separation between the observers including sudden death of entanglement. We also calculate the fidelity of the two-mode channel for non-vacuum Gaussian states and obtain bounds on classical and quantum capacities of a single-mode channel. Our framework can be directly applied to any continuous variable quantum information protocol in which the effects of acceleration or gravity cannot be neglected., 21 pages, 13 figures. A few typos corrected

In quantum communication protocols the existence of a shared reference frame between two spatially separated parties is normally presumed. However, in many practical situations we are faced with the problem of misaligned reference frames. In this paper, we study communication between two inertial observers who have partial knowledge about the Lorentz transformation that relates their frames of reference. Since every Lorentz transformation can be decomposed into a pure boost followed by a rotation, we begin by analysing the effects on communication when the parties have partial knowledge about the transformation relating their frames, when the transformation is either a rotation or pure boost. This then enables us to investigate how the efficiency of communication is affected due to partially correlated inertial reference frames related by an arbitrary Lorentz transformation. Furthermore, we show how the results of previous studies where reference frames are completely uncorrelated are recovered from our results in appropriate limits., 9 pages, 3 figures, typos corrected, figures updated

We derive the structure of the density matrix for two Unruh-DeWitt detectors coupled to a massless scalar field to all orders of perturbation theory, in spacetimes admitting a well-defined Wightman function. Calculating all of its leading terms enables us to fully characterize observable correlations, entanglement, and quantum discord. We apply these results to study detector responses in two locally flat topologically nontrivial spacetimes constructed from identifications of Minkowski space. We demonstrate how local statistics and detector-detector correlations depend on the global spacetime structure. In particular, we show that if the spacetime has a preferred direction, this direction may be inferred from the dependence of correlations between the two detectors on their orientation. While using such measurements to distinguish spacetimes with identical local geometry is apparently impractical, this effect points to fundamental connections between quantum field correlations and the structure of spacetime. This relationship may also be relevant in the phenomenology of the early Universe.

We consider the behaviour of bipartite and tripartite non-locality between fermionic entangled states shared by observers, one of whom uniformly accelerates. We find that while fermionic entanglement persists for arbitrarily large acceleration, the Bell/CHSH inequalities cannot be violated for sufficiently large but finite acceleration. However the Svetlichny inequality, which is a measure of genuine tripartite non-locality, can be violated for any finite value of the acceleration., 4 pages, pdflatex, 2 figures

Quantum communication without a shared reference frame or the construction of a relational quantum theory requires the notion of a quantum reference frame. We analyze aspects of quantum reference frames associated with non-compact groups, specifically the group of spatial translations and Galilean boosts. We begin by demonstrating how the usually employed group average, used to dispense of the notion of an external reference frame, leads to unphysical states when applied to reference frames associated with non-compact groups. However, we show that this average does lead naturally to a reduced state on the relative degrees of freedom of a system, which was previously considered by Angelo et al. [1]. We then study in detail the informational properties of this reduced state for systems of two and three particles in Gaussian states.