1. Streptococcus pneumoniae serotype 19A meningitis in well-vaccinated immunocompetent 13-month-old child: a case of PCV13 failure
- Author
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Abdul Monem Badran, Cécile Lagneaux, Simon Kayemba-Kay's, Tamas Kovacs, Anne Héron, Unité de Recherche Clinique et d'Evaluation Scientifique URC28 (URC28), Centre Hospitalier Victor Jousselin de Dreux, Service de Néonatalogie, Service de Pédiatrie, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Université Paris Descartes - Faculté de Pharmacie de Paris (UPD5 Pharmacie), Université Paris Descartes - Paris 5 (UPD5), Unité de Recherche Clinique et d'Evaluation Scientifique URC28 ( URC28 ), Université Paris Descartes - Faculté de Pharmacie de Paris ( UPD5 Pharmacie ), and Université Paris Descartes - Paris 5 ( UPD5 )
- Subjects
Serotype ,Asplenia ,Streptococcus pneumonia ,Streptococcus pneumoniae serotype ,Abdominal ultrasound ,education ,[ SDV.MHEP.PED ] Life Sciences [q-bio]/Human health and pathology/Pediatrics ,Failure ,Case Report ,PCV13 ,Case Reports ,03 medical and health sciences ,0302 clinical medicine ,Immune system ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,030225 pediatrics ,medicine ,030212 general & internal medicine ,toddlers ,[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics ,business.industry ,meningitis ,General Medicine ,medicine.disease ,[ SDV.MHEP.MI ] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Immunology ,[ SDV.IMM.VAC ] Life Sciences [q-bio]/Immunology/Vaccinology ,Bacterial meningitis ,[SDV.IMM.VAC]Life Sciences [q-bio]/Immunology/Vaccinology ,business ,Meningitis - Abstract
International audience; We report a 13-month-old immune-competent male child who was diagnosed with pneumococcal serotype 19A meningitis despite having received three PCV13 injections. Clinicians are reminded that bacterial meningitis can still occur, even in correctly vaccinated children. Investigations should include immune system screening along with abdominal ultrasound to exclude asplenia.
- Published
- 2016