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Needle‐free injection systems with high jet pressure have been used for seven decades for drug or vaccine administration via intradermal, subcutaneous, and intramuscular routes. These systems are used for the application of mesotherapy drugs in plastic surgery and dermatology. Platelet‐rich plasma (PRP) tissue regeneration is applied intradermally by a needle for different indications, such as wound healing and scar revision. To prevent complaints such as pain, erythema, and ecchymosis by patients during this application, PRP was applied using Dermojet, a jet injector system with a spring‐loaded system. In this study, after measuring the average platelet count in PRP preparations obtained from 18 volunteers, a 2.5 cc PRP shot into an empty tube was performed with Dermojet. The mean platelet count was measured in a homogenized tube. The same procedures were performed for platelet‐poor plasma (PPP). The platelet loss rates for PRP and PPP were compared. In addition, the amount of PRP in each shot of the Dermojet was calculated. When PRP and PPP were applied using the Dermojet, platelet loss was 8.41% and 8.33%, respectively. The difference in the number of platelets formed in PRP and PPP when applied with Dermojet was not statistically significant. PRP application with needle‐free injection systems, such as Dermojet, may be an alternative because of patient comfort and the negligible platelet loss compared with the PRP application with the standard needle injection. [ABSTRACT FROM AUTHOR]

Aim: Gynecomastia is the visible enlargement of the male breast tissue either due to physiologic, pathologic or drug-related causes. Physiological and pathological gynecomastia occurs because of the derangement of the estrogen and androgen metabolism. Drug-related gynecomastia is seen when using drugs affecting this hormone metabolism as well as a side effect of different drugs. Successful treatment of gynecomastia was reported with medical treatment and cessation of the possible causative drugs especially in early period, and with direct excision, endoscopic subcutaneous mastectomy and excision with liposuction treatments in the late period. Material and Methods: In this study, we reported our results of gynecomastia treatment with suction assisted wet liposuction in 3 different planes using 3 different thickness cannulas in Grade I, II and III patients. Forty five patients were operated between 2009 and 2019 using this technique in our clinique. All patients were followed for up to a minimum of 6 months to observe the complication rate and the final aesthetic result. Results: Within the 45 patients evaluated in this study, the complication rate was 6.7%, the success rate of the operation was 93.3% and the patient satisfaction was 91.1%. Gynecomastia treatment in general -especially liposuction- was reviewed and our results were evaluated based on the literature results. Conclusion: There are many different options for gynecomastia treatment. In this study, we concluded that in Grade I, II, and III patients good results can be achieved and patient satisfaction is high in gynecomastia treatment with wet liposuction. [ABSTRACT FROM AUTHOR]

Background: Nocardia farcinica differs from other species of Nocardia due to its multi-drug resistance and propensity to disseminate hematogenously. Cutaneous nocardiosis in immunocompetent patients is rare., Purpose: To describe the treatment and clinical trajectory of a 37-year-old male patient who was not immunocompromised and presented with a history of minor trauma from a canister and palpable subcutaneous draining nodules in the forearm. Purulent drainage was present. The injury had occurred 3 months before presentation., Results: Magnetic resonance imaging revealed multiple abscess foci up to 3 cm in diameter in the forearm muscles. The wound culture obtained after debridment indicated Nocardia farcinica as the cause. The case was difficult to manage despite serial debridements, negative pressure wound dressings, and culture-specific antibiotic treatments. The entire treatment process took approximately 7 months. The patient had 5 surgical interventions and more than 6 months of antibiotic treatment. Healing was eventually achieved but with a painful scar., Conclusion: Although nocardiosis has been documented to occur primarily in immunocompromised patients, it should be considered in the differential diagnosis of immunocompetent patients if there is a history of skin injury and a late-onset subcutaneous draining abscess resistant to common treatment regimens.