Search

Arthralgia, myalgia, acute interstitial pneumonia-like presentation, venous thromboembolism, cytopenia, secondary hemophagocytic lymphohistiocytosis and cytokine storm are the clinical and laboratory findings associated with Coronavirus disease (COVID-19), which may mimic rheumatic syndromes. Systemic lupus erythematosus (SLE) is a highly heterogeneous disease, and various clinical features can be seen in affected individuals. Differentiated diagnoses are quite broad in SLE. We present six patients with systemic lupus erythematosus and/ or antiphospholipid syndrome mimicking COVID-19 pneumonia.

Abstract Drought stress adversely affects plant growth, development, and yield. It can decrease seed germination, biomass accumulation, root proliferation, chlorophyll contents, and stomatal conductance. To overcome this critical issue, researchers suggest employing environmentally friendly approaches. The exogenous application of alanine (AL) acts as an osmolyte, which helps balance the cellular water under drought stress. It can also improve root architecture, biomass accumulation, and plant fertilizer use efficiency. Applying biochar can improve soil structure, water, and nutrient retention in soil, which are allied factors in enhancing plant growth under drought stress. Furthermore, the enrichment of potassium (K) in biochar also increases its availability to plants, directly regulating the stomatal conductance to alleviate drought stress. That’s why the current study aims to explore the combined effect of AL and potassium-enriched biochar (KBC) on fenugreek cultivated under drought stress. Four levels of AL (control, 2mM, 4mM, and 6mM) were applied with 0%, 1%, and 2% KBC in three replicates. Results showed that 2mM AL + 2%KBC showed significant improvement in plant length (5.24%), plant fresh weight (25.36%), plant dry weight (16.23%), chlorophyll a (7.80%), chlorophyll b (15.83%), total chlorophyll (10.65%) over the control under drought stress. A significant increase in shoot N, P, and K concentration compared to control under drought stress also validated the effectiveness of 2mM AL + 2%KBC. In conclusion, 2mM AL + 2%KBC is an effective amendment for alleviating drought stress in fenugreeks. Under drought stress, growers are recommended to apply 2mM AL + 2%KBC to achieve better fenugreek growth.

In this study, the effects of design-oriented STEM activities on preschool children were examined. In the research conducted with case study in qualitative research designs, 20 preschool children aged five years in a kindergarten formed the participants of the study. Design Oriented STEM Activities were completed with 24 sessions of 8 weeks, 3 days a week. Within the scope of the research, data were collected through observations, interviews and research diaries and content analysis was made. As a result of the analysis of the data, it was concluded that the applied design-oriented STEM education increased the problem-solving, communication and cooperation skills of the children, and that the STEM education process; It has been concluded that it raises the awareness of children and gives them a sense of responsibility. In addition, it has been concluded that STEM activities encourage children to solve problems and generate ideas, make permanent behavioral changes in children, and increase children's social and adaptation skills.

The purpose of the current study was to evaluate the undergraduate program of the Computer Education and Instructional Technology (CEIT) Department. CEIT department is an undergraduate program that trains information technology teachers. The study group of the study, which was designed according to the descriptive research model, was consisted of 461 CEIT graduates, who were selected by using the convenience sampling methods. Three instruments were used to collect data; a "Personal Information Form," the "Pedagogical Competence Perception Scale for the CEIT Graduates," the "Technological Competence Perception Scale for the CEIT Graduates." The data collection tools were developed by the researchers. When the results of the study are evaluated it is seen that the CEIT curriculum supports the participants in the acquisition of pedagogical competence more than the acquisition of the technological competence. When the pedagogical competence perceptions of the graduates are considered, it is seen that the graduates have high level competence perceptions about "Educational Planning and implementation, developing educational software and materials, educational communication competences, security and ethics in the use of information and communication technologies during the educational process, planning and implementation of the projects." When their perceptions of their technological competence are examined, it is seen that the graduates have moderate level of competence perceptions about "ability to solve problems in relation to the hardware installation and using visual software," while they have low level of competence perceptions about "ability to use system software and security of network and system." In this study, it was understood that the undergraduate program of the CEIT department, which trains future teachers of information technologies courses, is more sufficient in terms of developing pedagogical competence and less sufficient in terms of developing technological competence in students. In this context, the contents of the courses in the CEIT undergraduate program should be updated. Additionally, some studies should be conducted in order to develop the technological competence skills of the students attending the department.

Introduction: While empathy is generally regarded as a positive trait, the emergence of empathic anger among nurses can have adverse effects on their mental well-being and, more importantly, on their tendency for violence.Aim: The aim of the study was to determine the relationship between empathic anger and violence tendencies in nurses.Method: This cross-sectional study was conducted on 348 nurses who agreed to participate in the research working in a hospital in Erzurum. The study data were collected with a personal information form, empathic anger scale, and violence tendency scale. The data analyzed using One-Way ANOVA and independent samples t-tests, and Hierarchical regression analyses.Results: It was found that the mean Emphatic Anger Scale score of the nurses included in the study was 23.20 ± 5.66, and the Violence Tendencies Scale score was 44.35 ± 11.01. It was found that there was a positive, statistically significant relationship between the Emphatic Anger Scale scores and Violence Tendencies Scale mean scores of the nurses (p lt; 0.001). In the regression model, Emphatic Anger Scale scores were entered as the sole predictor, explaining 9.6% of the variance in violence tendency (R² = 0.096, Adj. R² = 0.093, p lt; 0.05).Conclusion: As a result, it shows that empathic anger in nurses has a significant and positive effect on violent tendencies. In addition, it was determined that as the empathic anger levels of the nurses increased, their level of violence tendencies also increased.

Aim: This study aimed to assess the potential for drug-drug interactions in adult patients admitted to the emergency departments.Material and Methods: This cross-sectional study included 410 patients who were admitted to the red zone of the emergency departments, examined, treated, and received multiple medications. Drug-drug interaction analysis was conducted using LexiInteract software.Results: The median age of patients was 63 (range, 19-96) years, with 55.4% (n=227) being female and 44.6% (n=183) were male. A total of 1,230 medications were identified among the patients. In 181 (44.1%) patients, 330 possible drug-drug interactions were detected. While there was no significant difference in the rate of drug-drug interactions between male and female patients (p=0.658), this rate was higher in patients aged 65 years and over (p=0.048) and patients with polypharmacy (p

Objective: The aim of this study was to evaluate the relationship between cardiovascular risk scores and the visceral adiposity index (VAI) in patients with psoriatic disease (PsD). Methods: A total of 101 PsD patients meeting psoriatic arthritis (CASPAR) criteria and 98 healthy individuals were included in this study. Systematic coronary risk evaluation index (SCORE), Framingham risk score (FS), and VAI values in patients and VAI values in healthy individuals were calculated. Results: The mean body mass index (BMI) (kg/m²) of the patients was 29.63±5.66. According to the SCORE measurements, the patients were classified as low risk, moderate risk, and high risk-53 (52.5%), 45 (44.6%), and 3 (3%), respectively. No patient was found to be at very high risk. According to the FS, the low-risk, moderate-risk, and high-risk patient rates were 72 (71.3%), 22 (21.8%), and 7 (6.9%), respectively. Statistically significantly higher rates of metabolic syndrome, obesity (BMI >30), and VAI levels were found in the PsA group compared to the healthy control group (p30 (obesity), diabetes mellitus, and hypertension compared to patients without these comorbidities (p

This study was aimed at designing and developing a learner-centered curriculum course for pre-service early childhood teachers considering their expectations, supporting active creation of lesson plans, and investigating course effectiveness. Participant self-reflections and course assistant feedback regarding lesson plans were gathered. At the semester end, participants evaluated their course expectations of developing knowledge and skills involving lesson planning. Through participants' lesson plans, self-reflections, and final evaluations, the designed learner-centered curriculum course was demonstrated effective. Gathering pre-service early childhood teachers' ideas during curriculum preparation made them active participants within the process as well as enabled them to recognize the significance of their ideas. It was also determined active participation to create lesson plans and one-on-one feedback improved pre-service teachers' lesson planning. Thus, this study can be seen as reflecting the promise of a designed learned-centered course.

Teachers are expected to have sufficient knowledge and skills on assistive technologies in order to use assistive technologies, which are defined as various technological tools and methods that facilitate the lives of individuals with special needs, in the field of education. Considering that this is related to undergraduate education programme in which teachers gain knowledge and skills in their fields. So it is important to consult the opinions and experiences of teacher candidates. The aim of this study, based on this, is to reveal the experiences and opinions of special education teacher candidates about the use of assistive technologies in education. For this purpose, 13 special education teacher candidates who continue their education were interviewed in the study carried out by using the phenomenology method, one of the qualitative research designs. The data obtained with an interview form consisting of 9 questions were analyzed by content analysis. As a result of the research, the participants found the use of assistive technology in special education mostly beneficial, especially the technology-related courses they took in undergraduate education; however, it was observed that they stated that the existing trainings were insufficient.

This article introduces basic strategies for teachers initiating translanguaging pedagogy for emergent bilingual students in mathematics classrooms to support linguistic identities, create inclusive environments, and enhance learning. The authors collaborated with Algebra 1 teachers who exclusively taught emergent bilingual students, implementing research-based strategies through monthly sessions focused on co-planning, co-teaching, and co-reflecting. Translanguaging emerged as a particularly effective strategy for enhancing student participation and mathematical comprehension.

Teaching science education has remained limited for students with intellectual and developmental disabilities (IDD), which, in turn, has resulted in an ongoing discrepancy between these students and their typically developing peers for decades. Although there is a growing body of research in effective teaching approaches aimed at overcoming this discrepancy, there is still a need to identify evidence-based practices for addressing this academic core content. The purpose of this meta-analysis was to (a) find out the skills taught in science education to students with IDD, (b) define the characteristics of instructional approaches or adaptations of instructional approaches used to teach science content and practices, (c) conduct visual and effect size analysis of science education studies meeting the Council for Exceptional Children (CEC) quality indicators (QIs; Cook et al., 2015), and (d) determine whether there are differences in effect sizes of science education studies meeting CEC QIs based on participant and intervention characteristics. Of 27 studies reviewed, 18 studies met all the CEC QIs. A meta-analysis of these 18 studies resulted in an overall medium effect size of 0.82 CI[subscript 95] (0.76, 0.87). While all the moderator variables showed a medium effect size in participant characteristics, intervention characteristics showed differences in effect sizes for comprehension-based learning and peer and researcher-implemented interventions.

Background: Throughout the course of an individual's lifespan, they may come across a diverse range of minor or significant incidents that have the potential to result in the development of scars on any region of their physique. These scars may also be a consequence of the body's innate responses to different stimuli. Various medicinal drugs and methods have been used to treat scars. Herbal remedies have long been popular. Cichorium intybus L., or chicory, has been used for centuries to treat numerous illnesses and deformities. Purpose: The primary objective and novelty of this research endeavor involve the investigation of potential therapeutic attributes inherent in extracts derived from different components of C. intybus (common chicory), encompassing the root, stem, flower, and whole herba. This will be accomplished through the utilization of in vitro scratch tests and in vitro cell migration assays. Additionally, the ash acquired from cremation, a method routinely employed by the general population, was also investigated. Study design: The focus of this investigation was to evaluate the wound healing effects of these extracts. The research encompassed a comprehensive examination of several components of the plant in order to ascertain the extracts that exhibited the highest efficacy. Methods: The study utilized the following approaches respectively to investigate the plant's wound healing abilities: collection and identification of plants, preparation of extracts, determination of phenolic compounds by HPLC-PDA, in vitro cell culture studies, cell viability analysis, wound healing analysis, statistical analysis. Results: The findings indicated that the stem extracts of C. intybus, with the exception of the hexane extract (Sample 1), demonstrated notable wound healing properties. According to the chromatography results the main component of extract is chlorogenic acid. The aforementioned findings offer significant contributions to the potential directions for future research within this particular sector. Conclusion: The evidence suggests that extracts from C. intybus have wound healing properties, highlighting its significance in traditional medicine and pharmaceutical research. Further investigation into active chemicals and mechanisms contributing to its wound healing properties is needed, potentially leading to advancements in wound healing therapies.