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1. Dysfibrinogenaemia associated with a defect in the aggregation of the fibrin monomers (Almeria I fibrinogen). A preliminary study.

Author

Vila V, Regañon E, Fernandez-Pavon A, and Aznar J

Subjects
Adult, Batroxobin metabolism, Female, Humans, Polymers analysis, Thrombin Time, Blood Coagulation Disorders blood, Fibrin analysis, Fibrinogen analysis, Fibrinogens, Abnormal
Abstract

A patient with functionally defective fibrinogen has been studied. Fibrinogen Almeria I was found to have a prolonged of latency time (LT) and a decrease in rate of gelation (RG) when plasma or isolated fibrinogen were activated by thrombin or reptilase. This fibrinogen also has the unusual formation of cross-linked fibrin; the existence of unpolymerized alpha chains was confirmed.

Published
1984
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