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Maternal vascular hypoperfusion is the most common cause of fetal growth restrict ion. Maternal oxidative status features are identifiable on placental pathology, and antepartum diagnostic methods are rapidly evolving. The current study was constructed to determine the maternal oxidative status by measuring serum ischemia modified albumin (IMA) levels in pregnancies complicated with idiopathic intrauterine growth restriction (IUGR). The current study was designed as a descriptive and cohort trial. A total of 87 pregnant women; 45 healthy controls and 42 pregnancies complicated with idiopathic IUGR were included to the study population. Maternal serum IMA concentration was measured prior to the administration of any medication. The perinatal outcomes of patie nts were also recorded. Maternal serum IMA concentration in pregnancies complicated by idiopathic IUGR was higher than in healthy controls. There was no significant difference between the groups (0.54±0.04 versus 0.55±0.06 ABSU, p: 0.314). IUGR is a significant pregnancy complication. Elevated oxidative stress which leads to an ischemic microenvironment is associated with IUGR. Maternal serum IMA which is a possible marker for oxidative stress is not increase in pregnancies complicated with idiopathic IUGR. [ABSTRACT FROM AUTHOR]

Kurjak Antenatal Neurodevelopmental Test (KANET) was developed for the assessment of fetal neurobehavior and the detection of neurological disorders. We aimed to evaluate the prenatal use of KANET scoring in fetuses with isolated ventriculomegaly in the third trimester of pregnancy. The present study was planned as a prospective and cohort trial. A total of 75 pregnant women; 41 healthy controls and 34 pregnancies with isolated mild ventriculomegaly fetuses were included in the study. All pregnant women were assessed with KANET scoring by 4 dimension ultrasound in the third trimester of pregnancy. The obstetric outcomes of the pregnant women were also recorded. The study and control groups exhibited no significant difference with respect to maternal age, body mass index, delivery week and other obstetric outcomes. The KANET scores of the fetuses (16±2 versus 15±2, p: 0.241) were similar between the study and control groups. Prenatally diagnosed isolated mild ventriculomegaly has not any effect on fetal neurobehavior which was assessed by KANET scoring in the third trimester gestation. The frequent and widespread use of 4 dimension ultrasound in obstetric routine practice would improve the early diagnosis of fetal neurological disorders. [ABSTRACT FROM AUTHOR]