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597 results on '"Toh, Yasushi"'

57. Impact of certification status of the institute and surgeon on short-term outcomes after surgery for thoracic esophageal cancer: evaluation using data on 16,752 patients from the National Clinical Database in Japan

Author

Motoyama, Satoru, Yamamoto, Hiroyuki, Miyata, Hiroaki, Yano, Masahiko, Yasuda, Takushi, Ohira, Masaichi, Kajiyama, Yoshiaki, Toh, Yasushi, Watanabe, Masayuki, Kakeji, Yoshihiro, Seto, Yasuyuki, Doki, Yuichiro, and Matsubara, Hisahiro

Published
2020
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61. Thoracic and cardiovascular surgery in Japan in 2016: Annual report by The Japanese Association for Thoracic Surgery

Author

Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery, Shimizu, Hideyuki, Endo, Shunsuke, Natsugoe, Shoji, Doki, Yuichiro, Hirata, Yasutaka, Kobayashi, Junjiro, Motomura, Noboru, Nakano, Kiyoharu, Nishida, Hiroshi, Okada, Morihito, Saiki, Yoshikatsu, Saito, Aya, Sato, Yukio, Tanemoto, Kazuo, Toh, Yasushi, Tsukihara, Hiroyuki, Wakui, Shinji, Yokomise, Hiroyasu, Masuda, Munetaka, Yokoi, Kohei, and Okita, Yutaka

Published
2019
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67. Thoracic and cardiovascular surgery in Japan during 2015: Annual report by The Japanese Association for Thoracic Surgery

Author

Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery, Masuda, Munetaka, Endo, Shunsuke, Natsugoe, Shoji, Shimizu, Hideyuki, Doki, Yuichiro, Hirata, Yasutaka, Kobayashi, Junjiro, Motomura, Noboru, Nakano, Kiyoharu, Nishida, Hiroshi, Okada, Morihito, Saiki, Yoshikatsu, Saito, Aya, Sato, Yukio, Tanemoto, Kazuo, Toh, Yasushi, Tsukihara, Hiroyuki, Wakui, Shinji, Yokomise, Hiroyasu, Yokoi, Kohei, and Okita, Yutaka

Published
2018
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72. Cachexia index as a prognostic predictor after resection of pancreatic ductal adenocarcinoma.

Author

Shimagaki, Tomonari, Sugimachi, Keishi, Mano, Yohei, Onishi, Emi, Iguchi, Tomohiro, Nakashima, Yuichiro, Sugiyama, Masahiko, Yamamoto, Manabu, Morita, Masaru, and Toh, Yasushi

Abstract

Aim: This study was performed to investigate the relationship between the preoperative cachexia index (CXI) and long‐term outcomes in patients who have undergone radical resection of pancreatic ductal adenocarcinoma (PDAC). Methods: In total, 144 patients who underwent pancreatic resection for treatment of PDAC were retrospectively analyzed. The relationship between the CXI and the patients' long‐term outcomes after PDAC resection was investigated. The CXI was calculated based on the preoperative skeletal muscle index, serum albumin level, and neutrophil‐to‐lymphocyte ratio. After propensity‐score matching, we compared clinicopathological features and outcomes. Results: The multivariate analysis showed that lymph node metastasis (hazard ratio [HR], 1.93; 95% confidence interval [CI], 1.16–3.23; P = 0.0118), R1 resection (HR, 57.20; 95% CI, 9.39–348.30; P < 0.0001), and a low CXI (HR, 2.10; 95% CI, 1.27–3.46; P = 0.0038) were independent and significant predictors of disease‐free survival (DFS) after PDAC resection. Moreover, a low CXI (HR, 3.14; 95% CI, 1.71–5.75; P = 0.0002) was an independent and significant predictor of overall survival (OS) after PDAC resection. After propensity‐score matching, the low CXI group had a significantly worse prognosis than the high CXI group for both DFS and OS. Conclusion: The CXI can be a useful prognostic factor for DFS and OS after pancreatic resection for treatment of PDAC. [ABSTRACT FROM AUTHOR]

Published
2023
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77. Decreased risk of esophageal cancer owing to cigarette and alcohol cessation in smokers and drinkers: a systematic review and meta-analysis

Author

Miyazaki, Tatsuya, Kitagawa, Yuko, Kuwano, Hiroyuki, Kusano, Motoyasu, Oyama, Tuneo, Muto, Manabu, Kato, Hiroyuki, Takeuchi, Hiroya, Toh, Yasushi, Doki, Yuichiro, Naomoto, Yoshio, Nemoto, Kenji, Matsubara, Hisahiro, Yanagisawa, Akio, Uno, Takashi, Kato, Ken, Yoshida, Masahiro, Kawakubo, Hirofumi, Booka, Eisuke, Kawamura, Osamu, Fukuchi, Minoru, Sakai, Makoto, Sohda, Makoto, Nakajima, Masanobu, and The Committee for the “Guidelines for diagnosis and treatment of carcinoma of the esophagus” of the Japan Esophageal Society

Published
2017
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78. A new scoring system with simple preoperative parameters as predictors of early recurrence of pancreatic ductal adenocarcinoma.

Author

Shimagaki, Tomonari, Sugimachi, Keishi, Mano, Yohei, Tomino, Takahiro, Onishi, Emi, Nakashima, Yuichiro, Sugiyama, Masahiko, Yamamoto, Manabu, Morita, Masaru, Shimokawa, Mototsugu, Yoshizumi, Tomoharu, and Toh, Yasushi

Subjects
PANCREATIC duct, RECEIVER operating characteristic curves, PLATELET lymphocyte ratio, LYMPHATIC metastasis, PLATELET count
Abstract

Background: Pancreatic ductal adenocarcinoma (PDAC) often recurs early after radical resection, and such early recurrence (ER) is associated with a poor prognosis. Predicting ER is useful for determining the optimal treatment. Methods: One hundred fifty-three patients who underwent pancreatectomy for PDAC were divided into an ER group (n = 54) and non-ER group (n = 99). Clinicopathological factors were compared between the groups, and the predictors of ER and prognosis after PDAC resection were examined. Results: The ER group had a higher platelet count, higher platelet-to-lymphocyte ratio (PLR), higher preoperative CA19-9 concentration, higher SPan-1 concentration, larger tumor diameter, and more lymph node metastasis. The receiver operating characteristic (ROC) curve analysis identified cut-off values for PLR, carbohydrate antigen 19–9 (CA19-9), SPan-1, and tumor diameter. In the multivariate analysis, a high PLR, high CA19-9, and tumor diameter of >3.1 cm were independent predictors of ER after resection (all p < 0.05). When the parameter exceeded the cut-off level, 1 point was given, and the total score of the three factors was defined as the ER prediction score. Next, our new ER prediction model using PLR, CA19-9 and tumor diameter (Logit(p) = 1.6 + 1.2 × high PLR + 0.7 × high CA19-9 + 0.5 × tumor diameter > 3.1cm) distinguished ER with an area under the curve of 0.763, a sensitivity of 85.2%, and a specificity of 55.6%. Conclusions: ER after resection of PDAC can be predicted by calculation of a score using the preoperative serum CA19-9 concentration, PLR, and tumor diameter. [ABSTRACT FROM AUTHOR]

Published
2023
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80. Significance of dissection in each regional lymph-node station of esophageal cancer based on efficacy index and recurrence patterns after curative esophagectomy.

Author

Kanemura, Takashi, Miyata, Hiroshi, Takeoka, Tomohira, Sugase, Takahito, Sugimura, Keijiro, Yamashita, Kotaro, Tanaka, Koji, Makino, Tomoki, Ota, Mitsuhiko, Yagi, Koichi, Toh, Yasushi, Seto, Yasuyuki, and Doki, Yuichiro

Abstract

Background: The optimal extent of lymph-node (LN) dissection in esophageal cancer has not been established. Although the frequency and patterns of recurrence in each regional LN station after radical dissection are important in determining the regional LNs of thoracic esophageal cancer to be routinely dissected, this information has not been investigated sufficiently. We studied the significance of dissection at each LN station based on their recurrence patterns. Methods: Six hundred and twelve patients with esophageal cancer who underwent curative esophagectomy were studied. The incidence and pattern of recurrence (systemic or non-systemic) at each regional LN station were analyzed. To compare the significance of dissection among regional LNs, the efficacy index (EI) was also calculated. Results: Regional LN recurrence was diagnosed in 101 (16.5%) patients. Among the regional LNs, recurrent laryngeal nerve, paraesophageal, and perigastric LNs showed higher EIs (3.1–6.7). Pretracheal and posterior thoracic para-aortic LNs showed low EIs (0–0.2). Supraclavicular LNs had moderate EIs (1.7–2.0). The recurrence rate was highest in the pretracheal LN, followed by the supraclavicular LNs. The majority (81.8%) of the pretracheal LN had a systemic recurrence, while about half (right: 60.0%, left: 43.8%) of the supraclavicular LNs had a systemic recurrence. Conclusion: Due to the high incidence of systemic recurrence or low EI for pretracheal and posterior thoracic para-aortic LNs, we suggest that these LN stations be regarded as non-regional LNs and be excluded from routine dissection. Supraclavicular LNs may also be excluded from routinely dissected stations. [ABSTRACT FROM AUTHOR]

Published
2023
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81. Esophageal stenosis and the Glasgow Prognostic Score as independent factors of poor prognosis for patients with locally advanced unresectable esophageal cancer treated with chemoradiotherapy (exploratory analysis of JCOG0303)

Author

Okuno, Tatsuya, Wakabayashi, Masashi, Kato, Ken, Shinoda, Masayuki, Katayama, Hiroshi, Igaki, Hiroyasu, Tsubosa, Yasuhiro, Kojima, Takashi, Okabe, Hiroshi, Kimura, Yusuke, Kawano, Tatsuyuki, Kosugi, Shinichi, Toh, Yasushi, Kato, Hoichi, Nakamura, Kenichi, Fukuda, Haruhiko, Ishikura, Satoshi, Ando, Nobutoshi, Kitagawa, Yuko, and Japan Esophageal Oncology Group/Japan Clinical Oncology Group

Published
2017
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84. Erratum to: Thoracic and cardiovascular surgery in Japan during 2013: Annual report by The Japanese Association for Thoracic Surgery

Author

Masuda, Munetaka, Kuwano, Hiroyuki, Okumura, Meinoshin, Arai, Hirokuni, Endo, Shunsuke, Doki, Yuichiro, Kobayashi, Junjiro, Motomura, Noboru, Nishida, Hiroshi, Saiki, Yoshikatsu, Tanaka, Fumihiro, Tanemoto, Kazuo, Toh, Yasushi, Yokomise, Hiroyasu, and Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery

Published
2017
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87. Thoracic and cardiovascular surgery in Japan during 2014: Annual report by The Japanese Association for Thoracic Surgery

Author

Masuda, Munetaka, Okumura, Meinoshin, Doki, Yuichiro, Endo, Shunsuke, Hirata, Yasutaka, Kobayashi, Junjiro, Kuwano, Hiroyuki, Motomura, Noboru, Nishida, Hiroshi, Saiki, Yoshikatsu, Saito, Aya, Shimizu, Hideyuki, Tanaka, Fumihiro, Tanemoto, Kazuo, Toh, Yasushi, Tsukihara, Hiroyuki, Wakui, Shinji, Yokomise, Hiroyasu, and Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery

Published
2016
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90. Erratum to: Thoracic and cardiovascular surgery in Japan during 2013: Annual report by The Japanese Association for Thoracic Surgery

Author

Masuda, Munetaka, Kuwano, Hiroyuki, Okumura, Meinoshin, Arai, Hirokuni, Endo, Shunsuke, Doki, Yuichiro, Kobayashi, Junjiro, Motomura, Noboru, Nishida, Hiroshi, Saiki, Yoshikatsu, Tanaka, Fumihiro, Tanemoto, Kazuo, Toh, Yasushi, Yokomise, Hiroyasu, and Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery

Published
2016
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92. Neo-adjuvant therapy or definitive chemoradiotherapy can improve laryngeal preservation rates in patients with cervical esophageal cancer. A Japanese nationwide survey

Author

Kato, Hiroyuki, Kitagawa, Yuko, Kuwano, Hiroyuki, Toh, Yasushi, Kusano, Motoyasu, Oyama, Tuneo, Muto, Manabu, Takeuchi, Hiroya, Doki, Yuichiro, Naomoto, Yoshio, Nemoto, Kenji, Matsubara, Hisahiro, Miyazaki, Tatsuya, Yanagisawa, Akio, Uno, Takashi, Kato, Ken, Yoshida, Masahiro, Kawakubo, Hirofumi, Booka, Eisuke, Nakajima, Masanobu, Kaneko, Koichi, Shiotani, Akihiro, and The Committee for the “Guidelines for diagnosis and treatment of carcinoma of the esophagus” in the Japan Esophageal Society

Published
2016
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95. A nation-wide survey of follow-up strategies for esophageal cancer patients after a curative esophagectomy or a complete response by definitive chemoradiotherapy in Japan

Author

Toh, Yasushi, Kitagawa, Yuko, Kuwano, Hiroyuki, Kusano, Motoyasu, Oyama, Tsuneo, Muto, Manabu, Kato, Hiroyuki, Takeuchi, Hiroya, Doki, Yuichiro, Naomoto, Yoshio, Nemoto, Kenji, Matsubara, Hisahiro, Miyazaki, Tatsuya, Yanagisawa, Akio, Uno, Takashi, Kato, Ken, Yoshida, Masahiro, Kawakubo, Hirofumi, and Booka, Eisuke

Published
2016
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99. Thoracic and cardiovascular surgery in Japan during 2013: Annual report by The Japanese Association for Thoracic Surgery

Author

Masuda, Munetaka, Kuwano, Hiroyuki, Okumura, Meinoshin, Arai, Hirokuni, Endo, Shunsuke, Doki, Yuichiro, Kobayashi, Junjiro, Motomura, Noboru, Nishida, Hiroshi, Saiki, Yoshikatsu, Tanaka, Fumihiro, Tanemoto, Kazuo, Toh, Yasushi, Yokomise, Hiroyasu, and Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery

Published
2015
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