Search

Focuses on the development of an HIV-based viral vector EboZ, that carries envelope proteins from the Zaire strain of Ebola virus. Role of James Wilson, who is the director of the Institute of Gene Therapy at the University of Pennsylvania, and is connected to the death of Jesse Gelsinger; Purpose of the vector for the treatment of cystic fibrosis; Success of the treatment in causing the transduction of tracheal epithelial cells; Warnings regarding the safety of the treatment.

Discusses tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL), a possible anticancer drug developed by Genetech and Immunex. Indication that the compound can cause liver damage as found in a study published in `Nature Medicine'; Safety profile of TRAIL; Details of the study by Stephen Strom and colleagues at the University of Pittsburg in Pennsylvania; Implications of Strom's findings.

Focuses on a study revealing that the outcome for people with diabetes and multivessel coronary-artery disease is better after myocardial infarction. Advantage they have if they have previously undergone coronary-artery bypass grafting (CABG) rather than percutaneous transluminal coronary angioplasty (PTCA); Details of the research of Katherine Detre and colleagues at the University of Pittsburgh in Pennsylvania; Speculation on the difference in mortality; Assertion that CABG should be the treatment of choice.