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Your search keyword '"Silvia Malguzzi"' showing total 2 results
2 results on '"Silvia Malguzzi"'

1. Which factors affect the occurence of severe cerebral lesions in preterm neonates who are born with intrauterine infection?

Author

Anna Locatelli, Marianna Andreani, Francesca Assi, Giuseppe Paterlini, Alessandro Ghidini, Silvia Malguzzi, Locatelli, A, Ghidini, A, Assi, F, Andreani, M, Malguzzi, S, and Paterlini, G

Subjects
Adult, medicine.medical_specialty, Leukomalacia, Periventricular, Uterus, Logistic regression, Lesion, Pregnancy, Risk Factors, medicine, Humans, Ultrasonography, Placental abruption, business.industry, Obstetrics, Infant, Newborn, Pregnancy Outcome, Obstetrics and Gynecology, Odds ratio, medicine.disease, medicine.anatomical_structure, Chorioamnionitis, In utero, Cohort, Gestation, Female, medicine.symptom, business, prematurity, infection, cerebral lesions, Infant, Premature
Abstract

Objective: The purpose of this study was to evaluate which factors affect the occurrence of neonatal ultrasonographic evidence of severe cerebral lesions in the presence of intrauterine infection. Study Design: From a cohort of 567 singleton neonates who were born between 24.0 and 31.6 weeks of gestation, we identified the 180 infants with histologic and/or clinical evidence of intrauterine infection. We excluded stillbirths and congenital anomalies. Obstetric and neonatal variables were related to evidence of severe neonatal ultrasonographic cerebral lesions with the use of logistic regression analysis. Results: Severe cerebral lesions were identified in 10% of infants (18/180). After we controlled for variables that were clinically relevant, logistic regression analysis demonstrated that ultrasound evidence of severe neonatal cerebral lesions was associated independently with antenatal administration of corticosteroids (adjusted odds ratio, 0.3; 95% CI, 0.11-0.88; P = .03) and occurrence of placental abruption (adjusted odds ratio, 5.4; 95% CI, 1.4-20.7; P = .02). Conclusion: Antenatal administration of corticosteroids in the presence of intrauterine infection has a protective effect on the risk of ultrasonographic evidence of severe neonatal cerebral lesions. © 2008 Mosby, Inc. All rights reserved.

Published
2008

2. Depression and Anxiety in Mothers Who Were Pregnant During the COVID-19 Outbreak in Northern Italy: The Role of Pandemic-Related Emotional Stress and Perceived Social Support.

Author

Grumi, Serena, Provenzi, Livio, Accorsi, Patrizia, Biasucci, Giacomo, Cavallini, Anna, Decembrino, Lidia, Falcone, Rossana, Fazzi, Elisa Maria, Gardella, Barbara, Giacchero, Roberta, Guerini, Paola, Grossi, Elena, Magnani, Maria Luisa, Mariani, Eloisa Maria, Nacinovich, Renata, Pantaleo, Dario, Pisoni, Camilla, Prefumo, Federico, Sabatini, Caterina, and Scelsa, Barbara

Subjects
COVID-19 pandemic, PSYCHOLOGICAL stress, SOCIAL support, MENTAL health services, PRENATAL depression, SARS-CoV-2
Abstract

The COVID-19 pandemic is a collective trauma that is threatening citizens' mental health resulting in increased emotional stress, reduced social support, and heightened risk for affective symptoms. The present study aimed to investigate the effects of antenatal pandemic-related emotional stress and perceived social support on the symptoms of depression and anxiety of mothers who were pregnant during the initial COVID-19 outbreak in northern Italy. A sample of 281 mothers was enrolled at eight maternity units in the first hotspot region of the COVID-19 outbreak in northern Italy. Participants filled out online questionnaires assessing the direct or indirect exposure to the SARS-CoV-2 virus, pandemic-related stress, perceived social support, as well as symptoms of depression and anxiety. Depressive and anxious symptomatology was above clinical concern, respectively, in 26 and 32% of the respondents. Mothers who reported no exposure to SARS-CoV-2 during pregnancy and those who reported at least one direct or indirect exposure did not differ in terms of affective symptoms. Continuous scores and risk for severe depression and anxiety were positively associated with prenatal pandemic-related emotional stress and negatively linked with perceived social support during pregnancy. Women who become mothers during the COVID-19 emergency may be at high risk for affective problems. Dedicated preventive programs are needed to provide adequate preventive support and care for maternal mental health during and after the COVID-19 pandemic. [ABSTRACT FROM AUTHOR]

Published
2021
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