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The combination of a transition-metal catalyst and organocatalyst was designed to achieve a highly enantioselective system for the allylic dearomatization reaction of naphthols with racemic secondary allylic alcohols. The desired β-naphthalenones, bearing an all-carbon quaternary center, were obtained in good yields with high chemo- and enantioselectivities. The cooperative catalytic system, involving a chiral iridium complex and phosphoric acid, provided measurable improvements in yields, and chemo- and enantioselectivities relative to single-catalyst systems. Control experiments indicated that the chiral iridium complex functions as a key species in the control of the absolute configuration, thus enabling the formation of both β-naphthalenone enantiomers by simply employing opposite enantiomeric ligands. [ABSTRACT FROM AUTHOR]

Take two: By employing two equivalents of an aldehyde in an asymmetric organocatalytic domino reaction, the nucleophilic enamine intermediate is also converted into the corresponding iminium species through oxidation with o‐iodoxybenzoic acid. Thus, polyfunctionalized cyclohexene derivatives are formed from two simple starting materials in good yields and stereoselectivities (see scheme; Bn=benzyl, EWG=electron‐withdrawing group). [ABSTRACT FROM AUTHOR]

The [3 + 3]-cyclization reaction of N-hydroxyphthalimide acrylates with N-tosyl ketimines proceeds in moderate to high yields and with excellent enantiomeric excess. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "N-Heterocyclic Carbene/Lewis Acid Catalyzed Enantioselective Aerobic Annulation of α,β-Unsaturated Aldehydes with 1,3-Dicarbonyl Compounds" by D. Xie and others, published in the "Journal of Organic Chemistry" in 2016.

An abstract of the article "Enantioselective Construction of Spirocyclic Oxindole Derivatives with Multiple Stereocenters via an Organocatalytic Michael/Aldol/Hemiacetalization Cascade Reaction," by Luyi Zhu and colleagues is presented.

Chemical reactions are presented for the article "Highly Enantio- and Diastereoselective L-Proline Derived Acetylglucose Amide Catalyzed Aldol Reaction of Ketones to Aldehydes under Solvent-Free Conditions" by X. Han and colleagues, published in the journal "Synlett" in 2015.

A diagram is presented which illustrates imines (II) cycloaddition to oxindole-derived enals (I).