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Aim: To present the systematic ultrasonographic assessment in fetal osteochondrodysplasias and to evaluate the fetal MRI intake, as a complementary exploration to US, in the prenatal diagnosis and perinatal prognosis of fetal nonlethal osteochondrodysplasias. Material and methods: In this tertiary multicentre study were included 37 cases diagnosed prenatally with various entities in the category of nonlethal fetal osteochondrodysplasias. The initial diagnosis was carried out by the routine or detailed ultrasound examination. Fetal MRI was accomplished for selected cases., Results: Nonlethal skeletal dysplasia was suspected and then diagnosed after 17 gestational weeks. The suspicion of osteochondrodysplasia as a reference diagnosis element has required systematic and thorough ultrasound examination. Fetal MRI is a valuable exploration, complementary to prenatal ultrasound bringing in very useful details for the diagnosis of osteochondrodysplasias. The global diagnosis of skeletal dysplasia depends to a great extent on the genetic or biochemical abnormality that causes them., Conclusions: US is always the fundamental screening exploration for fetal assessment in nonlethal osteochondrodysplasias. The details brought by the fetal MRI are useful, and the exploration is harmless for the fetus and the mother. Certain diagnosis cannot be accurate and complete without the contribution of genetics, maternal and fetal medicine, obstetrics or radiology.

Introduction. Diaphragmatic hernia represents the presence of abdominal organs in the thoracic cavity. It has an incidence of 1 in 3500 births and it associates a high neonatal mortality. Left diaphragmatic hernia is the most frequent form. Case report. We present the case of a 32-year-old patient, G2P1, who had a fetal anatomy scan performed in our department. The first-trimester screening of the patient showed a combined risk of 1/5800. Our morphology scan showed a female fetus of 22 weeks and 5 days who presented a herniation of the abdominal organs (stomach, intestine, liver) in the thorax through a left diaphragmatic defect. The left fetal lung presented with a hyperechogenic mass with systemic vascularisation on Doppler exam, with origin from the descending aorta. We suspected a pulmonary sequestration. We excluded the presence of coexisting craniofacial or cardiac defects. An amniocentesis and investigations in order to exclude the Pallister-Killian syndrome were performed. We infirmed the presence of chromosomal anomalies. We performed a fetal MRI scan that confirmed our diagnostic. We evaluated the severity of the defect by calculating O-LHR which established a medium severity degree. The patient is advised to undergo FETO fetoscopic intervention, taking into consideration the inclusion and exclusion criteria of the TOTAL trial randomised international study. The patient refuses the fetoscopic intervention and benefits from antenatal follow-up with monitoring of the O-LHR, the volume of amniotic liquid and cervical length. Results. The birth took place by caesarean section at 38 weeks of gestation and the newborn deceased in the first day of life in the neonatal surgery department. Conclusions. The corroboration of imagistic techniques allows a complete evaluation and establishes the prognosis of fetuses with diaphragmatic hernia. [ABSTRACT FROM AUTHOR]

Introduction. Cervical-facial fetal tumors are an entity. Head and neck tumors are able to influence the vital prognosis at postnatal birth due to respiratory obstruction. The teratoma is most commonly seen in the neonatal solid, but only about 5% of the teratomas are located in the cervical-facial region. Early ultrasound imaging is the gold standard for the diagnosis of fetal abnormalities, while prenatal 3D ultrasound and prenatal nuclear magnetic resonance imaging (MRI) are complementary tools to establish a more accurate diagnosis. Methodology. We present a clinical case of prenatalversus- nasal suspected pathology, predominantly on the right side of the face, diagnosed by ultrasound at 26 weeks and 6 days of gestation. In addition to 2D and 4D ultrasound, the patient was referred to a reference hospital, where a fetal MRI was performed. The presumptive diagnosis was teratoma and fibrochondroma, tumors that can be solitary associated with one of the PAI or Goldenhar syndromes, but without a morphological facial argument for one of these syndromes. Postnatally, the established diagnosis was teratoma/nasal dermoid, with intrathermoid extension. During the postnatal period, the option of performing the surgical section of the tumor was discussed and adopted by a multidisciplinary team. The histopathological examination confirmed our suspicion and had the objective of a maturated frontonasal teratoma. Conclusions. The clinical significance of these births comes from the postnatal complications that they can cause, due to the over-the-air birth effects of the newborn. [ABSTRACT FROM AUTHOR]