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Reports that the complete genome sequence of a serogroup A strain of Neisseria meningitidis, Z2491, has been determined. The international collaborative effort between the Sanger Centre in Cambridge, England, the Max-Planck Institute in Berlin, Germany, and the Wellcome Trust Centre in Oxford, England; Occurrence of repeat arrays suggesting that antigenic variation mediated by gene conversion might occur widely.

States that researchers have linked mutations in cathepsin C with the autosomal recessive disorder Papillon-LeFevre syndrome (PLS). Role of PLS in periodontitis and tool loss; Symptoms and rarity of the disorder.