1. Molecular-genetic imaging of cancer.
- Author
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Minn I, Menezes ME, Sarkar S, Yarlagadda K, Das SK, Emdad L, Sarkar D, Fisher PB, and Pomper MG
- Subjects
- Animals, Humans, Gene Expression, Multimodal Imaging methods, Neoplasms diagnosis, Neoplasms genetics
- Abstract
Molecular-genetic imaging of cancer using nonviral delivery systems has great potential for clinical application as a safe, efficient, noninvasive tool for visualization of various cellular processes including detection of cancer, and its attendant metastases. In recent years, significant effort has been expended in overcoming technical hurdles to enable clinical adoption of molecular-genetic imaging. This chapter will provide an introduction to the components of molecular-genetic imaging and recent advances on each component leading to safe, efficient clinical applications for detecting cancer. Combination with therapy, namely, generating molecular-genetic theranostic constructs, will provide further impetus for clinical translation of this promising technology., (© 2014 Elsevier Inc. All rights reserved.)
- Published
- 2014
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