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1. Fluorescent strip sensor for rapid determination of toxinsElectronic supplementary information (ESI) available: Detailed information of the whole experimental procedure, the characterization of QD–aptamer conjugation and factors. See DOI: 10.1039/c0cc04032k

Author

WangThese authors contributed equally to this paper., Libing, Chen, Wei, Ma, Wenwei, Liu, Liqinag, Ma, Wei, Zhao, Yuan, Zhu, Yingyue, Xu, Liguang, Kuang, Hua, and Xu, Chuanlai

Subjects
*OCHRATOXINS, *FLUORESCENCE, *EXPERIMENTS, *QUANTUM dots, *NANOPARTICLES, *COLLOIDAL gold, *SOLUTION (Chemistry)
Abstract

Here, we report a simple fluorescent strip sensor based on aptamer–quantum dots technology that can meet toxin monitoring demands using ochratoxin A (OTA) as a model toxin. The limit of the detection (LOD) for the fluorescent strip was 1.9 ng mL−1, while the time needed for the detection is only 10 min; this conforms to the standards of World Health Organization (WHO) or better. Overall functional parameters are also better than the analogous characteristics of gold nanoparticle strips.High selectivity was maintained as well, making them suitable for the samples with complex solution composition. [ABSTRACT FROM AUTHOR]

Published
2011

2. Colorimetric screening of bacterial enzyme activity and inhibition based on the aggregation of gold nanoparticlesElectronic supplementary information (ESI) available: Synthesis of substrate, the enzymatic inhibition assay, and tests on bacterial strains. See DOI: 10.1039/b818853j

Author

Tingting JiangT. J. and R. L. contributed equally to the work in this paper., Rongrong Liu, Xianfeng Huang, Huajun Feng, Weiling Teo, and Bengang Xing

Subjects
*COLORIMETRIC analysis, *COLLOIDAL gold, *MICROBIAL enzymes, *BETA lactamases, *ENZYME activation, *ENZYME inhibitors
Abstract

A simple and novel gold nanoparticle (Au-NPs) based colorimetric method has been developed for efficient screening of class A β-lactamase (Bla) activity and inhibitors in vitroand in bacterial strains. [ABSTRACT FROM AUTHOR]

Published
2009
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3. Electrochemical sensor for the detection of estradiol based on electropolymerized molecularly imprinted polythioaniline film with signal amplification using gold nanoparticles

Author

Cecilia Cristea, Nicole Jaffrezic-Renault, Anca Florea, Francis Vocanson, Robert Săndulescu, Interfaces & biosensors - Interfaces & biocapteurs, Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Université Cluj-Napoca, facultatea, Laboratoire Hubert Curien [Saint Etienne] (LHC), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS), and 'This paper was published under the frame of European Social Found, Human Resources Development Operational Programme 2007-2013, project no. POSDRU/159/1.5/S/136893'.

Subjects
17-BETA-ESTRADIOL, 02 engineering and technology, Electrochemistry, 01 natural sciences, lcsh:Chemistry, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Gold nanoparticles, Detection limit, Molecularly imprinted polymer, p-Aminothiophenol, Chromatography, Estradiol, Chemistry, 010401 analytical chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Electrochemical gas sensor, Linear range, lcsh:Industrial electrochemistry, lcsh:QD1-999, Colloidal gold, Linear sweep voltammetry, POLYMERS, 0210 nano-technology, Selectivity, [CHIM.OTHE]Chemical Sciences/Other, lcsh:TP250-261
Abstract

A sensitive electrochemical molecularly imprinted sensor was developed for the detection of estradiol, by electropolymerization of p-aminothiophenol functionalized gold nanoparticles in the presence of estradiol as template molecule. The extraction of the template leads to the formation of cavities that are able to recognize and bind estradiol with high affinity. The performance of the developed sensor for the detection of estradiol was investigated by linear sweep voltammetry using a hexacyanoferrate/hexacyanoferrite solution as redox probe. The molecularly imprinted sensor exhibits a broad linear range, between 3.6 fM and 3.6 nM and a limit of quantification of 1.09 fM. Compared to the non-imprinted sensor, the imprinted sensor exhibits high affinity for the binding of estradiol. Moreover, selectivity studies, performed towards binding of testosterone, a hormone with similar chemical structure, proved high sensor selectivity. Furthermore, the molecularly imprinted sensor was applied for the analysis of spiked river samples with good recoveries. Keywords: Molecularly imprinted polymer, p-Aminothiophenol, Gold nanoparticles, Estradiol

Published
2015