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Allergic contact dermatitis, case report, patch tests, benzoic acid, CAS-No. 10310-32-4, serial dilutions, tribenoside Keywords: allergic contact dermatitis; benzoic acid; case report; CAS-No. 10310-32-4; patch tests; serial dilutions; tribenoside EN allergic contact dermatitis benzoic acid case report CAS-No. 10310-32-4 patch tests serial dilutions tribenoside 718 719 2 11/18/21 20211201 NES 211201 CASE REPORT A 48-year-old female patient presented to our clinic with a 2-week history of erythematous and itchy dermatitis around her anus (Figure 1). GLO:FQV/01dec21:cod13952-fig-0001.jpg PHOTO (COLOR): 1 Positive patch tests reactions to Procto-Glyvenol crème gl Patch tests were performed with the European baseline series complemented with lidocaine 5.0% pet., cetyl alcohol 5.0% pet., benzisothiazolinone 0.1% pet. [Extracted from the article]

Second, in our case report, the patch tests with splint scrapings were positive, but only because the splint had been contaminated with the genuine culprit, the diclofenac gel. Allergic contact dermatitis, case report, diclofenac, patch tests, propylene glycol, retained allergen, topical drug Keywords: allergic contact dermatitis; case report; diclofenac; patch tests; propylene glycol; retained allergen; topical drug EN allergic contact dermatitis case report diclofenac patch tests propylene glycol retained allergen topical drug 475 476 2 09/21/21 20211001 NES 211001 CASE REPORT A 45-year-old woman was referred to our department for the investigation of a localized eczema on the right ankle with secondary extension. [Extracted from the article]

Exposure to hair dye is the most frequent route of sensitisation to para-phenylenediamine ( PPD), a common contact allergen. International studies have examined the profile of PPD, but Australian-sourced information is lacking. Patients are often dissatisfied with advice to stop dyeing their hair. This study examines patients' characteristics, patch test results and outcomes of PPD allergy from a single Australian centre, through a retrospective analysis of patch test data from 2006 to 2013 at the Liverpool Hospital Dermatology Department. It reviews the science of hair dye allergy, examines alternative hair dyes and investigates strategies for hair dyeing. Of 584 patients, 11 were allergic to PPD. Our PPD allergy prevalence rate of 2% is at the lower end of international reported rates. About half these patients also react to para-toluenediamine ( PTD). Affected patients experience a significant lifestyle disturbance. In all, 78% tried alternative hair dyes after the patch test diagnosis and more than half continued to dye their hair. Alternative non- PPD hair dyes are available but the marketplace can be confusing. Although some patients are able to tolerate alternative hair dyes, caution is needed as the risk of developing an allergy to other hair dye ingredients, especially PTD, is high. [ABSTRACT FROM AUTHOR]

Drug skin tests can be helpful in determining the cause of a cutaneous adverse drug reaction (CADR). Patch tests and prick tests can be performed with any commercialized form of a drug. Intradermal tests (IDTs) have a greater value, but their techniques have not been standardized. Moreover, IDTs can be done only if an injectable form of the drug is commercialized and are restricted to patients with nonsevere CADR. Prick tests and IDTs are used in investigating immediate hypersensitivity. Patch tests both with IDTs with delayed readings are helpful for maculopapular rash and generalized or localized eczema. Results obtained with drug skin tests in β-lactam sensitization have been extensively published, but fortunately, during the last few years the value of skin tests in CADR due to other drug classes (e.g., synergistins, platinium salts or radiocontrast medias) was also studied. The analysis of recent literature permits to propose which tests to choose for each clinical feature of CADR and to give the list of all drugs, having had patch tests with positive results but, emphasizes the lack of standardization in performing and reading IDTs. This standardization is absolutely necessary to determine the thresholds of specificity of the IDT. Except for IDTs, drug skin tests induce only rarely adverse reactions. False-positive results can occur and should be considered by testing new products. The negative predictive value of drug skin tests is a crucial point that will have to be studied in more detail in the near future. [ABSTRACT FROM AUTHOR]

We have studied a group of 104 patients with pompholyx. to investigate the relationship between allergotogical factors and its etiopathogenesis, The following examinations were performed, blood sampling routine tests and IgE levels. allergological tests (patch, prick. intradennal. and oral renovation tests with nickel sulphate), skin biopsy to exclude pemphigus vulgarism or bullous pemphigoid. An accurate history of familial and personal allergic diathesis was enquired for and various possible aggravating factors (season. microclimate, perspiration and emotional stress) were considered. The results were age `and sex-matched with a healthy control group (208 Subjects). We found familial and personal atopic diathesis in 50% of patients versus 11.5% of controls (P < 0.001); 39 positivity on patch testing 20.19% versus 6.25% of the control group (P<0.001) the % of Patients allergic to nicked reached 26% meluding those (6 Patients) reacting to the oral propagation test season 143 patients) and hyperhidrosis (38) were the aggravating factors most commonly claimed. We detected no correlation between age, sex, grading of pompholyx, and the allergological parameters investigated. Though several different allergological findings have previously been reported indydhidroiss their role in its pathogenses has not yet been fully explained. We think that different haptens or antigens can produce the same clinical and histological picture of pompholyx in predisposed subjects [ABSTRACT FROM AUTHOR]

Forty-eight patients with a positive patch test to potassium dichromate 0.5 % were retested after 4-7 years; 38 patients (79 %) still had a positive patch test. Chromate allergy seems to be persistent. In 72 % of the cases a history of occupational exposure to chromates could be proved. [ABSTRACT FROM AUTHOR]

High frequencies of contact allergy to fragrance ingredients have been reported in recent years. Only approximately 70–80% are detected by fragrance allergens in the standard patch test series. This investigation compares the patch test reactions to fine fragrances with reactions to fragrance mix (FM), balsam of Peru (BP) ( Myroxylon pereirae resin) and a fragrance series. 641 consecutive patients with eczema were patch tested with the European standard series and with selected fine fragrances. Those who were positive to 1 of the fine fragrances or the FM or BP were also tested with the fragrance series. 95 (14.8%) patients were found to have a positive patch test reaction to FM or BP; 41 (6.4%) had positive results to fragrance no. 1 and 29 (4.5%) to no. 2. 9 (9.5% of the 95 positive patients) had a positive reaction to fine fragrances and a negative reaction to all other fragrance allergens in the standard series. These findings indicate that testing with fine fragrances can add to our evaluation of fragrance-sensitive patients. [ABSTRACT FROM AUTHOR]