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7. A modification in an open centre training system for increasing the crotch angles of peach scaffold branches

Author

Abdel-Rahman M.A. Mohamed, Heba F. Sayed, Lidia Sas Paszt, and Augustyn Mika

Subjects
pruning peach, open centre, pruning modification, fruit training, de-branched top, crotch angles, Agriculture (General), S1-972
Abstract

One-year-old 'Florida Prince' cultivar peach trees grafted on a 'Nemaguard' rootstock were planted in the early spring of 2018 at the Centre of Agricultural Research and Experiments, Minia University, located in southwest Egypt. The trees were planted 5 × 5 m in a randomised complete block design with four replicates, with ten trees in each replicate. In the late spring, two different pruning systems were applied; traditional open centre (OC) and de-branched top trees (DBT). The OC trees were headed at 80 cm above the ground. DBT is a modification of the OC, but no heading was undertaken and the new shoot growth arising from the 20 cm at the top of the plant were removed. Before the winter pruning took place, measurements were taken on the upper two opposite branches. The average length and diameter values of the upper two opposite branches at the top of the trees trained to the OC were higher than those trained with the DBT. In contrast, the distance between the upper two branches (25 cm) at the top of the DBT trees was significantly higher. Likewise, the values of the crotch angles (48°) and the number of branches (81 of 100 branches) that showed desired crotch angles (more than 40°) were remarkably higher in the trees trained with the DBT. After the winter pruning took place, the DBT trees were higher than the OC trees. Additionally, the trees trained with the DBT had low pruning costs and took less time. Moreover, the pruning wood weight of the DBT trees was about half of the pruning wood weight of the OC trees. In conclusion, the DBT training system showed the desired impact on the crotch angles and the tested pruning characteristics.

Published
2021
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18. Effect of foliar application of sida compound fertilizer on growth, yield, and fruit chemical composition of ‘early superior’ grapevine

Author

Mohamed Abdel-Rahman M.A., Abdel-Aziz Faruk H., Mohamed Moawd A., and Gobara Ali

Subjects
sida compound, seaweed, ‘early superior’ cv., grapevines, berry quality, Plant culture, SB1-1110
Abstract

This experiment aimed at studying the effect of Sida Compound fertilizer containing seaweed extract, natural fertilizers, growth promoters and micronutrients in chelated form on growth, yield and berry quality of table grape ‘Early Superior’. Foliar application of Sida Compound at concentration 0.05 to 0.20%, three times in a season increased shoot length, leaf area and content of N, P and K in the leaves as well as total soluble solids and total sugar contents in fruits. Yield of fruits increased by 29 and 14%, depending on the season.

Published
2013
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22. Basheer—The Sufi

Author

Rahman, M.A., Rehman, M.A., and Rahman, Zahira

Published
2009

27. Serum iron and total iron binding capacity in severely malnourished children

Author

Md. Atiar Rahman, M.A. Mannan and Hamidur Rahman

Subjects
iron, malnourished children, plasma protein, total iron binding capacity, Therapeutics. Pharmacology, RM1-950
Abstract

Serum iron, total iron binding capacity and plasma protein of severely malnourished children of 12-59 months of age were compared with that of normal healthy children. Mean serum total protein and albumin level in normal children were 76.33 ± 0.51, 43.50 ± 0.38 gm/l respectively which was significantly higher (p

Published
2007

30. The Totem

Author

Rahman, M.A. and Krishnan, K.M.

Published
1998

33. Evaluation of a bearingless PM motor with wide magnetic gaps

Author

Asama, J., Amada, M., Tanabe, N., Miyamoto, N., Chiba, A., Iwasaki, S., Takemoto, M., Fukao, T., and Rahman, M.A.

Subjects
Centrifugal pumps -- Analysis, Magnetic bearings -- Analysis, Business, Electronics, Electronics and electrical industries
Published
2010

36. Building dynamic social network from sensory data feed

Author

Rahman, M.A., El Saddik, A., and Gueaieb, W.

Subjects
Fuzzy logic, Fuzzy algorithms -- Usage, Fuzzy logic -- Usage, Fuzzy systems -- Usage, Online social networks -- Analysis, Telemetry -- Analysis
Published
2010

38. Global injury morbidity and mortality from 1990 to 2017: Results from the global burden of disease study 2017

Author

James, S.L. Castle, C.D. Dingels, Z.V. Fox, J.T. Hamilton, E.B. Liu, Z. Roberts, N.L.S. Sylte, D.O. Henry, N.J. LeGrand, K.E. Abdelalim, A. Abdoli, A. Abdollahpour, I. Abdulkader, R.S. Abedi, A. Abosetugn, A.E. Abushouk, A.I. Adebayo, O.M. Agudelo-Botero, M. Ahmad, T. Ahmed, R. Ahmed, M.B. Aichour, M.T.E. Alahdab, F. Alamene, G.M. Alanezi, F.M. Alebel, A. Alema, N.M. Alghnam, S.A. Al-Hajj, S. Ali, B.A. Ali, S. Alikhani, M. Alinia, C. Alipour, V. Aljunid, S.M. Almasi-Hashiani, A. Almasri, N.A. Altirkawi, K. Amer, Y.S.A. Amini, S. Amit, A.M.L. Andrei, C.L. Ansari-Moghaddam, A. Antonio, C.A.T. Appiah, S.C.Y. Arabloo, J. Arab-Zozani, M. Arefi, Z. Aremu, O. Ariani, F. Arora, A. Asaad, M. Asghari, B. Awoke, N. Quintanilla, B.P.A. Ayano, G. Ayanore, M.A. Azari, S. Azarian, G. Badawi, A. Badiye, A.D. Bagli, E. Baig, A.A. Bairwa, M. Bakhtiari, A. Balachandran, A. Banach, M. Banerjee, S.K. Banik, P.C. Banstola, A. Barker-Collo, S.L. Bärnighausen, T.W. Barrero, L.H. Barzegar, A. Bayati, M. Baye, B.A. Bedi, N. Behzadifar, M. Bekuma, T.T. Belete, H. Benjet, C. Bennett, D.A. Bensenor, I.M. Berhe, K. Bhardwaj, P. Bhat, A.G. Bhattacharyya, K. Bibi, S. Bijani, A. Sayeed, M.S.B. Borges, G. Borzì, A.M. Boufous, S. Brazinova, A. Briko, N.I. Budhathoki, S.S. Car, J. Cárdenas, R. Carvalho, F. Castaldelli-Maia, J.M. Castañeda-Orjuela, C.A. Castelpietra, G. Catalá-López, F. Cerin, E. Chandan, J.S. Chanie, W.F. Chattu, S.K. Chattu, V.K. Chatziralli, I. Chaudhary, N. Cho, D.Y. Chowdhury, M.A.K. Chu, D.-T. Colquhoun, S.M. Constantin, M.-M. Costa, V.M. Damiani, G. Daryani, A. Dávila-Cervantes, C.A. Demeke, F.M. Demis, A.B. Demoz, G.T. Demsie, D.G. Derakhshani, A. Deribe, K. Desai, R. Nasab, M.D. Dias da Silva, D. Forooshani, Z.S.D. Doyle, K.E. Driscoll, T.R. Dubljanin, E. Adema, B.D. Eagan, A.W. Eftekhari, A. Ehsani-Chimeh, E. El Sayed Zaki, M. Elemineh, D.A. El-Jaafary, S.I. El-Khatib, Z. Ellingsen, C.L. Emamian, M.H. Endalew, D.A. Eskandarieh, S. Faris, P.S. Faro, A. Farzadfar, F. Fatahi, Y. Fekadu, W. Ferede, T.Y. Fereshtehnejad, S.-M. Fernandes, E. Ferrara, P. Feyissa, G.T. Filip, I. Fischer, F. Folayan, M.O. Foroutan, M. Francis, J.M. Franklin, R.C. Fukumoto, T. Geberemariyam, B.S. Gebre, A.K. Gebremedhin, K.B. Gebremeskel, G.G. Gebremichael, B. Gedefaw, G.A. Geta, B. Ghafourifard, M. Ghamari, F. Ghashghaee, A. Gholamian, A. Gill, T.K. Goulart, A.C. Grada, A. Grivna, M. Gubari, M.I.M. Guimarães, R.A. Guo, Y. Gupta, G. Haagsma, J.A. Hafezi-Nejad, N. Bidgoli, H.H. Hall, B.J. Hamadeh, R.R. Hamidi, S. Haro, J.M. Hasan, M.M. Hasanzadeh, A. Hassanipour, S. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hayat, K. Hendrie, D. Heydarpour, F. Híjar, M. Ho, H.C. Hoang, C.L. Hole, M.K. Holla, R. Hossain, N. Hosseinzadeh, M. Hostiuc, S. Hu, G. Ibitoye, S.E. Ilesanmi, O.S. Ilic, I. Ilic, M.D. Inbaraj, L.R. Indriasih, E. Irvani, S.S.N. Islam, S.M.S. Mofizul Islam, M. Ivers, R.Q. Jacobsen, K.H. Jahani, M.A. Jahanmehr, N. Jakovljevic, M. Jalilian, F. Jayaraman, S. Jayatilleke, A.U. Jha, R.P. John-Akinola, Y.O. Jonas, J.B. Joseph, N. Joukar, F. Jozwiak, J.J. Jungari, S.B. Jürisson, M. Kabir, A. Kadel, R. Kahsay, A. Kalankesh, L.R. Kalhor, R. Kamil, T.A. Kanchan, T. Kapoor, N. Karami, M. Kasaeian, A. Kassaye, H.G. Kavetskyy, T. Kebede, H.K. Keiyoro, P.N. Kelbore, A.G. Kelkay, B. Khader, Y.S. Khafaie, M.A. Khalid, N. Khalil, I.A. Khalilov, R. Khammarnia, M. Khan, E.A. Khan, M. Khanna, T. Khazaie, H. Shadmani, F.K. Khundkar, R. Kiirithio, D.N. Kim, Y.-E. Kim, D. Kim, Y.J. Kisa, A. Kisa, S. Komaki, H. Kondlahalli, S.K.M. Korshunov, V.A. Koyanagi, A. Kraemer, M.U.G. Krishan, K. Bicer, B.K. Kugbey, N. Kumar, V. Kumar, N. Anil Kumar, G. Kumar, M. Kumaresh, G. Kurmi, O.P. Kuti, O. Vecchia, C.L. Lami, F.H. Lamichhane, P. Lang, J.J. Lansingh, V.C. Laryea, D.O. Lasrado, S. Latifi, A. Lauriola, P. Leasher, J.L. Lee, S.W.H. Lenjebo, T.L. Levi, M. Li, S. Linn, S. Liu, X. Lopez, A.D. Lotufo, P.A. Lunevicius, R. Lyons, R.A. Madadin, M. El Razek, M.M.A. Mahotra, N.B. Majdan, M. Majeed, A. Malagon-Rojas, J.N. Maled, V. Malekzadeh, R. Malta, D.C. Manafi, N. Manafi, A. Manda, A.-L. Manjunatha, N. Mansour-Ghanaei, F. Mansouri, B. Mansournia, M.A. Maravilla, J.C. March, L.M. Mason-Jones, A.J. Masoumi, S.Z. Massenburg, B.B. Maulik, P.K. Meles, G.G. Melese, A. Melketsedik, Z.A. Memiah, P.T.N. Mendoza, W. Menezes, R.G. Mengesha, M.B. Mengesha, M.M. Meretoja, T.J. Meretoja, A. Merie, H.E. Mestrovic, T. Miazgowski, B. Miazgowski, T. Miller, T.R. Mini, G.K. Mirica, A. Mirrakhimov, E.M. Mirzaei-Alavijeh, M. Mithra, P. Moazen, B. Moghadaszadeh, M. Mohamadi, E. Mohammad, Y. Mohammad, K.A. Darwesh, A.M. Mezerji, N.M.G. Mohammadian-Hafshejani, A. Mohammadoo-Khorasani, M. Mohammadpourhodki, R. Mohammed, S. Mohammed, J.A. Mohebi, F. Molokhia, M. Monasta, L. Moodley, Y. Moosazadeh, M. Moradi, M. Moradi, G. Moradi-Lakeh, M. Moradpour, F. Morawska, L. Velásquez, I.M. Morisaki, N. Morrison, S.D. Mossie, T.B. Muluneh, A.G. Murthy, S. Musa, K.I. Mustafa, G. Nabhan, A.F. Nagarajan, A.J. Naik, G. Naimzada, M.D. Najafi, F. Nangia, V. Nascimento, B.R. Naserbakht, M. Nayak, V. Ndwandwe, D.E. Negoi, I. Ngunjiri, J.W. Nguyen, C.T. Nguyen, H.L.T. Nikbakhsh, R. Ningrum, D.N.A. Nnaji, C.A. Nyasulu, P.S. Ogbo, F.A. Oghenetega, O.B. Oh, I.-H. Okunga, E.W. Olagunju, A.T. Olagunju, T.O. Bali, A.O. Onwujekwe, O.E. Asante, K.O. Orpana, H.M. Ota, E. Otstavnov, N. Otstavnov, S.S. Mahesh, P.A. Padubidri, J.R. Pakhale, S. Pakshir, K. Panda-Jonas, S. Park, E.-K. Patel, S.K. Pathak, A. Pati, S. Patton, G.C. Paulos, K. Peden, A.E. Pepito, V.C.F. Pereira, J. Pham, H.Q. Phillips, M.R. Pinheiro, M. Polibin, R.V. Polinder, S. Poustchi, H. Prakash, S. Pribadi, D.R.A. Puri, P. Syed, Z.Q. Rabiee, M. Rabiee, N. Radfar, A. Rafay, A. Rafiee, A. Rafiei, A. Rahim, F. Rahimi, S. Rahimi-Movaghar, V. Rahman, M.A. Rajabpour-Sanati, A. Rajati, F. Rakovac, I. Ranganathan, K. Rao, S.J. Rashedi, V. Rastogi, P. Rathi, P. Rawaf, S. Rawal, L. Rawassizadeh, R. Renjith, V. Renzaho, A.M.N. Resnikoff, S. Rezapour, A. Ribeiro, A.I. Rickard, J. González, C.M.R. Ronfani, L. Roshandel, G. Saad, A.M. Sabde, Y.D. Sabour, S. Saddik, B. Safari, S. Safari-Faramani, R. Safarpour, H. Safdarian, M. Mohammad Sajadi, S. Salamati, P. Salehi, F. Zahabi, S.S. Rashad Salem, M.R. Salem, H. Salman, O. Salz, I. Samy, A.M. Sanabria, J. Riera, L.S. Santric Milicevic, M.M. Sarker, A.R. Sarveazad, A. Sathian, B. Sawhney, M. Sawyer, S.M. Saxena, S. Sayyah, M. Schwebel, D.C. Seedat, S. Senthilkumaran, S. Sepanlou, S.G. Seyedmousavi, S. Sha, F. Shaahmadi, F. Shahabi, S. Shaikh, M.A. Shams-Beyranvand, M. Shamsizadeh, M. Sharif-Alhoseini, M. Sharifi, H. Sheikh, A. Shigematsu, M. Shin, J.I. Shiri, R. Siabani, S. Sigfusdottir, I.D. Singh, P.K. Singh, J.A. Sinha, D.N. Smarandache, C.-G. Smith, E.U.R. Soheili, A. Soleymani, B. Soltanian, A.R. Soriano, J.B. Sorrie, M.B. Soyiri, I.N. Stein, D.J. Stokes, M.A. Mu'awiyyah, B.S. Suleria, H.A.R. Sykes, B.L. Tabarés-Seisdedos, R. Tabb, K.M. Taddele, B.W. Tadesse, D.B. Tamiru, A.T. Tarigan, I.U. Tefera, Y.M. Tehrani-Banihashemi, A. Tekle, M.G. Tekulu, G.H. Tesema, A.K. Tesfay, B.E. Thapar, R. Tilahune, A.B. Tlaye, K.G. Tohidinik, H.R. Topor-Madry, R. Tran, B.X. Tran, K.B. Tripathy, J.P. Tsai, A.C. Car, L.T. Ullah, S. Ullah, I. Umar, M. Unnikrishnan, B. Upadhyay, E. Uthman, O.A. Valdez, P.R. Vasankari, T.J. Venketasubramanian, N. Violante, F.S. Vlassov, V. Waheed, Y. Weldesamuel, G.T. Werdecker, A. Wiangkham, T. Wolde, H.F. Woldeyes, D.H. Wondafrash, D.Z. Wondmeneh, T.G. Wondmieneh, A.B. Wu, A.-M. Yadav, R. Yadollahpour, A. Yano, Y. Yaya, S. Yazdi-Feyzabadi, V. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. Youm, Y. Younis, M.Z. Yousefi, Z. Yu, Y. Yu, C. Yusefzadeh, H. Moghadam, T.Z. Zaidi, Z. Zaman, S.B. Zamani, M. Zamanian, M. Zandian, H. Zarei, A. Zare, F. Zhang, Z.-J. Zhang, Y. Zodpey, S. Dandona, L. Dandona, R. Degenhardt, L. Dharmaratne, S.D. Hay, S.I. Mokdad, A.H. Reiner, R.C., Jr. Sartorius, B. Vos, T.

Abstract

Background Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries. methods We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs). Findings In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100 000. In 1990, there were 354 064 302 (95% uncertainty interval: 338 174 876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100 000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100 000 to 3267 (3058 to 3505). Interpretation Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care. © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.

Published
2020

39. Estimating global injuries morbidity and mortality: Methods and data used in the Global Burden of Disease 2017 study

Author

James, S.L. Castle, C.D. Dingels, Z.V. Fox, J.T. Hamilton, E.B. Liu, Z. Roberts, N.L.S. Sylte, D.O. Bertolacci, G.J. Cunningham, M. Henry, N.J. Legrand, K.E. Abdelalim, A. Abdollahpour, I. Abdulkader, R.S. Abedi, A. Abegaz, K.H. Abosetugn, A.E. Abushouk, A.I. Adebayo, O.M. Adsuar, J.C. Advani, S.M. Agudelo-Botero, M. Ahmad, T. Ahmed, M.B. Ahmed, R. Aichour, M.T.E. Alahdab, F. Alanezi, F.M. Alema, N.M. Alemu, B.W. Alghnam, S.A. Ali, B.A. Ali, S. Alinia, C. Alipour, V. Aljunid, S.M. Almasi-Hashiani, A. Almasri, N.A. Altirkawi, K. Amer, Y.S.A. Andrei, C.L. Ansari-Moghaddam, A. Antonio, C.A.T. Anvari, D. Appiah, S.C.Y. Arabloo, J. Arab-Zozani, M. Arefi, Z. Aremu, O. Ariani, F. Arora, A. Asaad, M. Quintanilla, B.P.A. Ayano, G. Ayanore, M.A. Azarian, G. Badawi, A. Badiye, A.D. Baig, A.A. Bairwa, M. Bakhtiari, A. Balachandran, A. Banach, M. Banerjee, S.K. Banik, P.C. Banstola, A. Barker-Collo, S.L. Bärnighausen, T.W. Barzegar, A. Bayati, M. Bazargan-Hejazi, S. Bedi, N. Behzadifar, M. Belete, H. Bennett, D.A. Bensenor, I.M. Berhe, K. Bhagavathula, A.S. Bhardwaj, P. Bhat, A.G. Bhattacharyya, K. Bhutta, Z.A. Bibi, S. Bijani, A. Boloor, A. Borges, G. Borschmann, R. Borzì, A.M. Boufous, S. Braithwaite, D. Briko, N.I. Brugha, T. Budhathoki, S.S. Car, J. Cárdenas, R. Carvalho, F. Castaldelli-Maia, J.M. Castañeda-Orjuela, C.A. Castelpietra, G. Catalá-López, F. Cerin, E. Chandan, J.S. Chapman, J.R. Chattu, V.K. Chattu, S.K. Chatziralli, I. Chaudhary, N. Cho, D.Y. Choi, J.-Y.J. Chowdhury, M.A.K. Christopher, D.J. Chu, D.-T. Cicuttini, F.M. Coelho, J.M. Costa, V.M. Dahlawi, S.M.A. Daryani, A. Dávila-Cervantes, C.A. De Leo, D. Demeke, F.M. Demoz, G.T. Demsie, D.G. Deribe, K. Desai, R. Nasab, M.D. Da Silva, D.D. Forooshani, Z.S.D. Do, H.T. Doyle, K.E. Driscoll, T.R. Dubljanin, E. Adema, B.D. Eagan, A.W. Elemineh, D.A. El-Jaafary, S.I. El-Khatib, Z. Ellingsen, C.L. El Sayedzaki, M. Eskandarieh, S. Eyawo, O. Faris, P.S. Faro, A. Farzadfar, F. Fereshtehnejad, S.-M. Fernandes, E. Ferrara, P. Fischer, F. Folayan, M.O. Fomenkov, A.A. Foroutan, M. Francis, J.M. Franklin, R.C. Fukumoto, T. Geberemariyam, B.S. Gebremariam, H. Gebremedhin, K.B. Gebremeskel, L.G. Gebremeskel, G.G. Gebremichael, B. Gedefaw, G.A. Geta, B. Getenet, A.B. Ghafourifard, M. Ghamari, F. Gheshlagh, R.G. Gholamian, A. Gilani, S.A. Gill, T.K. Goudarzian, A.H. Goulart, A.C. Grada, A. Grivna, M. Guimarães, R.A. Guo, Y. Gupta, G. Haagsma, J.A. Hall, B.J. Hamadeh, R.R. Hamidi, S. Handiso, D.W. Haro, J.M. Hasanzadeh, A. Hassan, S. Hassanipour, S. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hendrie, D. Heydarpour, F. Híjar, M. Ho, H.C. Hoang, C.L. Hole, M.K. Holla, R. Hossain, N. Hosseinzadeh, M. Hostiuc, S. Hu, G. Ibitoye, S.E. Ilesanmi, O.S. Inbaraj, L.R. Irvani, S.S.N. Islam, M.M. Islam, S.M.S. Ivers, R.Q. Jahani, M.A. Jakovljevic, M. Jalilian, F. Jayaraman, S. Jayatilleke, A.U. Jha, R.P. John-Akinola, Y.O. Jonas, J.B. Jones, K.M. Joseph, N. Joukar, F. Jozwiak, J.J. Jungari, S.B. Jürisson, M. Kabir, A. Kahsay, A. Kalankesh, L.R. Kalhor, R. Kamil, T.A. Kanchan, T. Kapoor, N. Karami, M. Kasaeian, A. Kassaye, H.G. Kavetskyy, T. Kayode, G.A. Keiyoro, P.N. Kelbore, A.G. Khader, Y.S. Khafaie, M.A. Khalid, N. Khalil, I.A. Khalilov, R. Khan, M. Khan, E.A. Khan, J. Khanna, T. Khazaei, S. Khazaie, H. Khundkar, R. Kiirithio, D.N. Kim, Y.-E. Kim, Y.J. Kim, D. Kisa, S. Kisa, A. Komaki, H. Kondlahalli, S.K.M. Koolivand, A. Korshunov, V.A. Koyanagi, A. Kraemer, M.U.G. Krishan, K. Defo, B.K. Bicer, B.K. Kugbey, N. Kumar, N. Kumar, M. Kumar, V. Kumar, N. Kumaresh, G. Lami, F.H. Lansingh, V.C. Lasrado, S. Latifi, A. Lauriola, P. Vecchia, C.L. Leasher, J.L. Lee, S.W.H. Li, S. Liu, X. Lopez, A.D. Lotufo, P.A. Lyons, R.A. Machado, D.B. Madadin, M. Abd El Razek, M.M. Mahotra, N.B. Majdan, M. Majeed, A. Maled, V. Malta, D.C. Manafi, N. Manafi, A. Manda, A.-L. Manjunatha, N. Mansour-Ghanaei, F. Mansournia, M.A. Maravilla, J.C. Mason-Jones, A.J. Masoumi, S.Z. Massenburg, B.B. Maulik, P.K. Mehndiratta, M.M. Melketsedik, Z.A. Memiah, P.T.N. Mendoza, W. Menezes, R.G. Mengesha, M.M. Meretoja, T.J. Meretoja, A. Merie, H.E. Mestrovic, T. Miazgowski, B. Miazgowski, T. Miller, T.R. Mini, G.K. Mirica, A. Mirrakhimov, E.M. Mirzaei-Alavijeh, M. Mithra, P. Moazen, B. Moghadaszadeh, M. Mohamadi, E. Mohammad, Y. Darwesh, A.M. Mohammadian-Hafshejani, A. Mohammadpourhodki, R. Mohammed, S. Mohammed, J.A. Mohebi, F. Bandpei, M.A.M. Molokhia, M. Monasta, L. Moodley, Y. Moradi, M. Moradi, G. Moradi-Lakeh, M. Moradzadeh, R. Morawska, L. Velásquez, I.M. Morrison, S.D. Mossie, T.B. Muluneh, A.G. Musa, K.I. Mustafa, G. Naderi, M. Nagarajan, A.J. Naik, G. Naimzada, M.D. Najaf, F. Nangia, V. Nascimento, B.R. Naserbakht, M. Nayak, V. Nazari, J. Ndwandwe, D.E. Negoi, I. Ngunjiri, J.W. Nguyen, T.H. Nguyen, C.T. Nguyen, D.N. Nguyen, H.L.T. Nikbakhsh, R. Ningrum, D.N.A. Nnaji, C.A. Ofori-Asenso, R. Ogbo, F.A. Oghenetega, O.B. Oh, I.-H. Olagunju, A.T. Olagunju, T.O. Bali, A.O. Onwujekwe, O.E. Orpana, H.M. Ota, E. Otstavnov, N. Otstavnov, S.S. Mahesh, A.P. Padubidri, J.R. Pakhale, S. Pakshir, K. Panda-Jonas, S. Park, E.-K. Patel, S.K. Pathak, A. Pati, S. Paulos, K. Peden, A.E. Pepito, V.C.F. Pereira, J. Phillips, M.R. Polibin, R.V. Polinder, S. Pourmalek, F. Pourshams, A. Poustchi, H. Prakash, S. Pribadi, D.R.A. Puri, P. Syed, Z.Q. Rabiee, N. Rabiee, M. Radfar, A. Rafay, A. Rafee, A. Rafei, A. Rahim, F. Rahimi, S. Rahman, M.A. Rajabpour-Sanati, A. Rajati, F. Rakovac, I. Rao, S.J. Rashedi, V. Rastogi, P. Rathi, P. Rawaf, S. Rawal, L. Rawassizadeh, R. Renjith, V. Resnikoff, S. Rezapour, A. Ribeiro, A.I. Rickard, J. González, C.M.R. Roever, L. Ronfani, L. Roshandel, G. Saddik, B. Safarpour, H. Safdarian, M. Sajadi, S.M. Salamati, P. Salem, M.R.R. Salem, H. Salz, I. Samy, A.M. Sanabria, J. Riera, L.S. Milicevic, M.M.S. Sarker, A.R. Sarveazad, A. Sathian, B. Sawhney, M. Sayyah, M. Schwebel, D.C. Seedat, S. Senthilkumaran, S. Seyedmousavi, S. Sha, F. Shaahmadi, F. Shahabi, S. Shaikh, M.A. Shams-Beyranvand, M. Sheikh, A. Shigematsu, M. Shin, J.I. Shiri, R. Siabani, S. Sigfusdottir, I.D. Singh, J.A. Singh, P.K. Sinha, D.N. Soheili, A. Soriano, J.B. Sorrie, M.B. Soyiri, I.N. Stokes, M.A. Sufiyan, M.B. Sykes, B.L. Tabarés-Seisdedos, R. Tabb, K.M. Taddele, B.W. Tefera, Y.M. Tehrani-Banihashemi, A. Tekulu, G.H. Tesema, A.K.T. Tesfay, B.E. Thapar, R. Titova, M.V. Tlaye, K.G. Tohidinik, H.R. Topor-Madry, R. Tran, K.B. Tran, B.X. Tripathy, J.P. Tsai, A.C. Tsatsakis, A. Car, L.T. Ullah, I. Ullah, S. Unnikrishnan, B. Upadhyay, E. Uthman, O.A. Valdez, P.R. Vasankari, T.J. Veisani, Y. Venketasubramanian, N. Violante, F.S. Vlassov, V. Waheed, Y. Wang, Y.-P. Wiangkham, T. Wolde, H.F. Woldeyes, D.H. Wondmeneh, T.G. Wondmieneh, A.B. Wu, A.-M. Wyper, G.M.A. Yadav, R. Yadollahpour, A. Yano, Y. Yaya, S. Yazdi-Feyzabadi, V. Ye, P. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. Youm, Y. Younis, M.Z. Yousef, Z. Yu, C. Yu, Y. Moghadam, T.Z. Zaidi, Z. Zaman, S.B. Zamani, M. Zandian, H. Zarei, F. Zhang, Z.-J. Zhang, Y. Ziapour, A. Zodpey, S. Dandona, R. Dharmaratne, S.D. Hay, S.I. Mokdad, A.H. Pigott, D.M. Reiner, R.C. Vos, T.

Abstract

Background: While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disability that can occur in an injury, and must provide estimates with sufficient demographic, geographical and temporal detail to be useful for policy makers. The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet these criteria. Methods: In this study, we report and discuss the methods used in GBD 2017 for injury morbidity and mortality burden estimation. In summary, these methods included estimating cause-specific mortality for every cause of injury, and then estimating incidence for every cause of injury. Non-fatal disability for each cause is then calculated based on the probabilities of suffering from different types of bodily injury experienced. Results: GBD 2017 produced morbidity and mortality estimates for 38 causes of injury. Estimates were produced in terms of incidence, prevalence, years lived with disability, cause-specific mortality, years of life lost and disability-adjusted life-years for a 28-year period for 22 age groups, 195 countries and both sexes. Conclusions: GBD 2017 demonstrated a complex and sophisticated series of analytical steps using the largest known database of morbidity and mortality data on injuries. GBD 2017 results should be used to help inform injury prevention policy making and resource allocation. We also identify important avenues for improving injury burden estimation in the future. © Author(s) (or their employer(s)) 2020. Re-use permitted under CC B Y. Published by BMJ.

Published
2020

40. Real-time testing of WPT-based protection of three-phase VS PWM inverter-fed motors

Author

Saleh, S.A., Radwan, T.S., and Rahman, M.A.

Subjects
Wavelet transforms -- Properties, Electric inverters -- Design and construction, Pulse-duration modulation -- Methods, Voltage -- Measurement, Business, Computers, Electronics, Electronics and electrical industries
Abstract

This paper presents an experimental testing of a wavelet packet transform (WPT)-based technique for protecting and controlling three-phase voltage-source (VS) pulse-width modulated (PWM) inverters under extreme load conditions. The proposed technique is based on a two-level multiresolution analysis (MRA) applied on output currents of a 3 [phi] VS PWM inverter. The MRA aims to extract certain signatures, which are the second level highest frequency subband coefficients. These coefficients take a nonzero value for any signal that is short-duration, nonperiodic and nonstationary with impulse-super imposed high frequencies. Such a signal perfectly matches a current arising from any typical fault occurring in either the inverter legs or on the load side. The proposed technique is realized using a C-code hosted and executed by a dSPACE ds1102 controller board. The tested inverter supplies loads that include a 3 [phi] Y-connected R - L load, a 3 [phi] squirrel-cage induction motor and a 3 [phi] synchronous reluctance motor. The extreme load conditions include inverter open-leg, motor starting currents and different faults in motor stator windings. The experimental test results show accurate, fast, and effective response to all disturbances including fault currents by the proposed WPT-based technique. Index Terms--Daubechies (db4), motor protection, multiresolution analysis (MRA), wavelet packet transform (WPT), 3 [phi] voltage-source pulse-width modulated (VS PWM) inverters.

Published
2007

41. Effect of alpha-particle energies on CR-39 line-shape parameters using positron annihilation technique

Author

Abdel-Rahman, M.A., Abdel-Rahman, M., Abo-Elsoud, M., Eissa, M.F., and Lotfy, Y.A.

Subjects
Positron annihilation -- Methods -- Models, Physics, Models, Methods
Abstract

Polyally diglycol carbonate 'CR-39' is widely used as etched track type particle detector. Doppler broadening positron annihilation (DBPAT) provides direct information about core and valance electrons in (CR-39) due to [...]

Published
2006

42. Real-time testing of a WPT-based protection algorithm for three-phase power transformers

Author

Saleh, S.A. and Rahman, M.A.

Subjects
Wavelet transforms -- Research, Electric transformers -- Research, Algorithms -- Research, Algorithms -- Technology application, Magnetization -- Research, Algorithm, Technology application, Business, Computers, Electronics, Electronics and electrical industries
Abstract

This paper presents real-time implementation and testing of a wavelet-packet-transform-based algorithm for power transformer protection. The proposed algorithm is implemented using a DS1102 digital signal processor board and tested on two different three-phase power transformers. Different magnetizing inrush, normal (through-fault) and internal fault currents are investigated for different loading conditions. The results show a complete independence from both the transformer parameters and current transformer saturation. In addition, the proposed algorithm has reduced computational burden, high speed, high accuracy, small required memory, and high reliability. In all cases of the investigated internal faults, the proposed algorithm is capable of identifying the fault and generating a trip signal in less than a quarter cycle based on a 60-Hz system. Index Terms--Current transformer (CT) saturation and Daubechies wavelet (db4), current transformers (CTs), differential current, differential protection, internal faults, magnetizing inrush current, power transformer, wavelet transforms.

Published
2005

43. Real-time performance evaluation of a genetic-algorithm-based fuzzy logic controller for IPM motor drives

Author

Uddin, M. Nasir, Abido, M.A., and Rahman, M.A.

Subjects
Digital signal processors -- Research, Algorithms -- Research, Digital signal processor, Algorithm, Business, Computers, Electronics, Electronics and electrical industries
Abstract

This paper presents a novel speed control scheme using a genetic-based fuzzy logic controller (GFLC) for an interior permanent-magnet synchronous motor (IPMSM) drive. The proposed GFLC is developed to have less computational burden, which makes it suitable for real-time implementation. The parameters for the GFLC are tuned by genetic algorithm (GA). The complete drive incorporating the GFLC is successfully implemented in real-time using a digital signal processor board DS 1102 for a laboratory 1-hp interior permanent magnet motor. The efficacy of the proposed GFLC-based IPMSM drive is verified by simulation as well as experimental results at various operating conditions. A performance comparison with a conventional proportional--integral controller is also provided to show the superiority of the proposed controller. The proposed GFLC is found to be robust for high-performance industrial drive applications. Index Terms--Digital signal processor (DSP), fuzzy logic, genetic algorithm (GA), interior permanent-magnet (IPM) motor, real-time implementation, vector control.

Published
2005

45. Metabolic Pathway Prediction Using Non-Negative Matrix Factorization with Improved Precision.

Author

Basher, Abdur Rahman M.A., Mclaughlin, Ryan J., and Hallam, Steven J.

Subjects
*NONNEGATIVE matrices, *MATRIX decomposition, *KEY performance indicators (Management), *MACHINE learning, *CELL populations, *MICROBIAL communities
Abstract

Machine learning provides a probabilistic framework for metabolic pathway inference from genomic sequence information at different levels of complexity and completion. However, several challenges, including pathway features engineering, multiple mapping of enzymatic reactions, and emergent or distributed metabolism within populations or communities of cells, can limit prediction performance. In this article, we present triUMPF (triple non-negative matrix factorization [NMF] with community detection for metabolic pathway inference), which combines three stages of NMF to capture myriad relationships between enzymes and pathways within a graph network. This is followed by community detection to extract a higher-order structure based on the clustering of vertices that share similar statistical properties. We evaluated triUMPF performance by using experimental datasets manifesting diverse multi-label properties, including Tier 1 genomes from the BioCyc collection of organismal Pathway/Genome Databases and low complexity microbial communities. Resulting performance metrics equaled or exceeded other prediction methods on organismal genomes with improved precision on multi-organismal datasets. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

46. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-Adjusted life-years for 29 cancer groups, 1990 to 2017: A systematic analysis for the global burden of disease study

Author

Fitzmaurice, C. Abate, D. Abbasi, N. Abbastabar, H. Abd-Allah, F. Abdel-Rahman, O. Abdelalim, A. Abdoli, A. Abdollahpour, I. Abdulle, A.S.M. Abebe, N.D. Abraha, H.N. Abu-Raddad, L.J. Abualhasan, A. Adedeji, I.A. Advani, S.M. Afarideh, M. Afshari, M. Aghaali, M. Agius, D. Agrawal, S. Ahmadi, A. Ahmadian, E. Ahmadpour, E. Ahmed, M.B. Akbari, M.E. Akinyemiju, T. Al-Aly, Z. Alabdulkader, A.M. Alahdab, F. Alam, T. Alamene, G.M. Alemnew, B.T.T. Alene, K.A. Alinia, C. Alipour, V. Aljunid, S.M. Bakeshei, F.A. Almadi, M.A.H. Almasi-Hashiani, A. Alsharif, U. Alsowaidi, S. Alvis-Guzman, N. Amini, E. Amini, S. Amoako, Y.A. Anbari, Z. Anber, N.H. Andrei, C.L. Anjomshoa, M. Ansari, F. Ansariadi, A. Appiah, S.C.Y. Arab-Zozani, M. Arabloo, J. Arefi, Z. Aremu, O. Areri, H.A. Artaman, A. Asayesh, H. Asfaw, E.T. Ashagre, A.F. Assadi, R. Ataeinia, B. Atalay, H.T. Ataro, Z. Atique, S. Ausloos, M. Avila-Burgos, L. Avokpaho, E.F.G.A. Awasthi, A. Awoke, N. Ayala Quintanilla, B.P. Ayanore, M.A. Ayele, H.T. Babaee, E. Bacha, U. Badawi, A. Bagherzadeh, M. Bagli, E. Balakrishnan, S. Balouchi, A. Barnighausen, T.W. Battista, R.J. Behzadifar, M. Behzadifar, M. Bekele, B.B. Belay, Y.B. Belayneh, Y.M. Berfield, K.K.S. Berhane, A. Bernabe, E. Beuran, M. Bhakta, N. Bhattacharyya, K. Biadgo, B. Bijani, A. Bin Sayeed, M.S. Birungi, C. Bisignano, C. Bitew, H. Bjorge, T. Bleyer, A. Bogale, K.A. Bojia, H.A. Borzi, A.M. Bosetti, C. Bou-Orm, I.R. Brenner, H. Brewer, J.D. Briko, A.N. Briko, N.I. Bustamante-Teixeira, M.T. Butt, Z.A. Carreras, G. Carrero, J.J. Carvalho, F. Castro, C. Castro, F. Catala-Lopez, F. Cerin, E. Chaiah, Y. Chanie, W.F. Chattu, V.K. Chaturvedi, P. Chauhan, N.S. Chehrazi, M. Chiang, P.P.-C. Chichiabellu, T.Y. Chido-Amajuoyi, O.G. Chimed-Ochir, O. Choi, J.-Y.J. Christopher, D.J. Chu, D.-T. Constantin, M.-M. Costa, V.M. Crocetti, E. Crowe, C.S. Curado, M.P. Dahlawi, S.M.A. Damiani, G. Darwish, A.H. Daryani, A. Das Neves, J. Demeke, F.M. Demis, A.B. Demissie, B.W. Demoz, G.T. Denova-Gutierrez, E. Derakhshani, A. Deribe, K.S. Desai, R. Desalegn, B.B. Desta, M. Dey, S. Dharmaratne, S.D. Dhimal, M. Diaz, D. Dinberu, M.T.T. Djalalinia, S. Doku, D.T. Drake, T.M. Dubey, M. Dubljanin, E. Duken, E.E. Ebrahimi, H. Effiong, A. Eftekhari, A. El Sayed, I. Zaki, M.E.S. El-Jaafary, S.I. El-Khatib, Z. Elemineh, D.A. Elkout, H. Ellenbogen, R.G. Elsharkawy, A. Emamian, M.H. Endalew, D.A. Endries, A.Y. Eshrati, B. Fadhil, I. Fallah, V. Faramarzi, M. Farhangi, M.A. Farioli, A. Farzadfar, F. Fentahun, N. Fernandes, E. Feyissa, G.T. Filip, I. Fischer, F. Fisher, J.L. Force, L.M. Foroutan, M. Freitas, M. Fukumoto, T. Futran, N.D. Gallus, S. Gankpe, F.G. Gayesa, R.T. Gebrehiwot, T.T. Gebremeskel, G.G. Gedefaw, G.A. Gelaw, B.K. Geta, B. Getachew, S. Gezae, K.E. Ghafourifard, M. Ghajar, A. Ghashghaee, A. Gholamian, A. Gill, P.S. Ginindza, T.T.G. Girmay, A. Gizaw, M. Gomez, R.S. Gopalani, S.V. Gorini, G. Goulart, B.N.G. Grada, A. Ribeiro Guerra, M. Guimaraes, A.L.S. Gupta, P.C. Gupta, R. Hadkhale, K. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Hanfore, L.K. Haro, J.M. Hasankhani, M. Hasanzadeh, A. Hassen, H.Y. Hay, R.J. Hay, S.I. Henok, A. Henry, N.J. Herteliu, C. Hidru, H.D. Hoang, C.L. Hole, M.K. Hoogar, P. Horita, N. Hosgood, H.D. Hosseini, M. Hosseinzadeh, M. Hostiuc, M. Hostiuc, S. Househ, M. Hussen, M.M. Ileanu, B. Ilic, M.D. Innos, K. Irvani, S.S.N. Iseh, K.R. Islam, S.M.S. Islami, F. Jafari Balalami, N. Jafarinia, M. Jahangiry, L. Jahani, M.A. Jahanmehr, N. Jakovljevic, M. James, S.L. Javanbakht, M. Jayaraman, S. Jee, S.H. Jenabi, E. Jha, R.P. Jonas, J.B. Jonnagaddala, J. Joo, T. Jungari, S.B. Jurisson, M. Kabir, A. Kamangar, F. Karch, A. Karimi, N. Karimian, A. Kasaeian, A. Kasahun, G.G. Kassa, B. Kassa, T.D. Kassaw, M.W. Kaul, A. Keiyoro, P.N. Kelbore, A.G. Kerbo, A.A. Khader, Y.S. Khalilarjmandi, M. Khan, E.A. Khan, G. Khang, Y.-H. Khatab, K. Khater, A. Khayamzadeh, M. Khazaee-Pool, M. Khazaei, S. Khoja, A.T. Khosravi, M.H. Khubchandani, J. Kianipour, N. Kim, D. Kim, Y.J. Kisa, A. Kisa, S. Kissimova-Skarbek, K. Komaki, H. Koyanagi, A. Krohn, K.J. Bicer, B.K. Kugbey, N. Kumar, V. Kuupiel, D. La Vecchia, C. Lad, D.P. Lake, E.A. Lakew, A.M. Lal, D.K. Lami, F.H. Lan, Q. Lasrado, S. Lauriola, P. Lazarus, J.V. Leigh, J. Leshargie, C.T. Liao, Y. Limenih, M.A. Listl, S. Lopez, A.D. Lopukhov, P.D. Lunevicius, R. Madadin, M. Magdeldin, S. El Razek, H.M.A. Majeed, A. Maleki, A. Malekzadeh, R. Manafi, A. Manafi, N. Manamo, W.A. Mansourian, M. Mansournia, M.A. Mantovani, L.G. Maroufizadeh, S. Martini, S.M.S. Mashamba-Thompson, T.P. Massenburg, B.B. Maswabi, M.T. Mathur, M.R. McAlinden, C. McKee, M. Meheretu, H.A.A. Mehrotra, R. Mehta, V. Meier, T. Melaku, Y.A. Meles, G.G. Meles, H.G. Melese, A. Melku, M. Memiah, P.T.N. Mendoza, W. Menezes, R.G. Merat, S. Meretoja, T.J. Mestrovic, T. Miazgowski, B. Miazgowski, T. Mihretie, K.M.M. Miller, T.R. Mills, E.J. Mir, S.M. Mirzaei, H. Mirzaei, H.R. Mishra, R. Moazen, B. Mohammad, D.K. Mohammad, K.A. Mohammad, Y. Darwesh, A.M. Mohammadbeigi, A. Mohammadi, H. Mohammadi, M. Mohammadian, M. Mohammadian-Hafshejani, A. Mohammadoo-Khorasani, M. Mohammadpourhodki, R. Mohammed, A.S. Mohammed, J.A. Mohammed, S. Mohebi, F. Mokdad, A.H. Monasta, L. Moodley, Y. Moosazadeh, M. Moossavi, M. Moradi, G. Moradi-Joo, M. Moradi-Lakeh, M. Moradpour, F. Morawska, L. Morgado-Da-costa, J. Morisaki, N. Morrison, S.D. Mosapour, A. Mousavi, S.M. Muche, A.A. Muhammed, O.S.S. Musa, J. Nabhan, A.R. Naderi, M. Nagarajan, A.J. Nagel, G. Nahvijou, A. Naik, G. Najafi, F. Naldi, L. Nam, H.S. Nasiri, N. Nazari, J. Negoi, I. Neupane, S. Newcomb, P.A. Nggada, H.A. Ngunjiri, J.W. Nguyen, C.T. Nikniaz, L. Ningrum, D.N.A. Nirayo, Y.L. Nixon, M.R. Nnaji, C.A. Nojomi, M. Nosratnejad, S. Shiadeh, M.N. Obsa, M.S. Ofori-Asenso, R. Ogbo, F.A. Oh, I.-H. Olagunju, A.T. Olagunju, T.O. Oluwasanu, M.M. Omonisi, A.E. Onwujekwe, O.E. Oommen, A.M. Oren, E. Ortega-Altamirano, D.D.V. Ota, E. Otstavnov, S.S. Owolabi, M.O. P A, M. Padubidri, J.R. Pakhale, S. Pakpour, A.H. Pana, A. Park, E.-K. Parsian, H. Pashaei, T. Patel, S. Patil, S.T. Pennini, A. Pereira, D.M. Piccinelli, C. Pillay, J.D. Pirestani, M. Pishgar, F. Postma, M.J. Pourjafar, H. Pourmalek, F. Pourshams, A. Prakash, S. Prasad, N. Qorbani, M. Rabiee, M. Rabiee, N. Radfar, A. Rafiei, A. Rahim, F. Rahimi, M. Rahman, M.A. Rajati, F. Rana, S.M. Raoofi, S. Rath, G.K. Rawaf, D.L. Rawaf, S. Reiner, R.C. Renzaho, A.M.N. Rezaei, N. Rezapour, A. Ribeiro, A.I. Ribeiro, D. Ronfani, L. Roro, E.M. Roshandel, G. Rostami, A. Saad, R.S. Sabbagh, P. Sabour, S. Saddik, B. Safiri, S. Sahebkar, A. Salahshoor, M.R. Salehi, F. Salem, H. Salem, M.R. Salimzadeh, H. Salomon, J.A. Samy, A.M. Sanabria, J. Santric Milicevic, M.M. Sartorius, B. Sarveazad, A. Sathian, B. Satpathy, M. Savic, M. Sawhney, M. Sayyah, M. Schneider, I.J.C. Schottker, B. Sekerija, M. Sepanlou, S.G. Sepehrimanesh, M. Seyedmousavi, S. Shaahmadi, F. Shabaninejad, H. Shahbaz, M. Shaikh, M.A. Shamshirian, A. Shamsizadeh, M. Sharafi, H. Sharafi, Z. Sharif, M. Sharifi, A. Sharifi, H. Sharma, R. Sheikh, A. Shirkoohi, R. Shukla, S.R. Si, S. Siabani, S. Silva, D.A.S. Silveira, D.G.A. Singh, A. Singh, J.A. Sisay, S. Sitas, F. Sobngwi, E. Soofi, M. Soriano, J.B. Stathopoulou, V. Sufiyan, M.B. Tabares-Seisdedos, R. Tabuchi, T. Takahashi, K. Tamtaji, O.R. Tarawneh, M.R. Tassew, S.G. Taymoori, P. Tehrani-Banihashemi, A. Temsah, M.-H. Temsah, O. Tesfay, B.E. Tesfay, F.H. Teshale, M.Y. Tessema, G.A. Thapa, S. Tlaye, K.G. Topor-Madry, R. Tovani-Palone, M.R. Traini, E. Tran, B.X. Tran, K.B. Tsadik, A.G. Ullah, I. Uthman, O.A. Vacante, M. Vaezi, M. Varona Perez, P. Veisani, Y. Vidale, S. Violante, F.S. Vlassov, V. Vollset, S.E. Vos, T. Vosoughi, K. Vu, G.T. Vujcic, I.S. Wabinga, H. Wachamo, T.M. Wagnew, F.S. Waheed, Y. Weldegebreal, F. Weldesamuel, G.T. Wijeratne, T. Wondafrash, D.Z. Wonde, T.E. Wondmieneh, A.B. Workie, H.M. Yadav, R. Yadegar, A. Yadollahpour, A. Yaseri, M. Yazdi-Feyzabadi, V. Yeshaneh, A. Yimam, M.A. Yimer, E.M. Yisma, E. Yonemoto, N. Younis, M.Z. Yousefi, B. Yousefifard, M. Yu, C. Zabeh, E. Zadnik, V. Moghadam, T.Z. Zaidi, Z. Zamani, M. Zandian, H. Zangeneh, A. Zaki, L. Zendehdel, K. Zenebe, Z.M. Zewale, T.A. Ziapour, A. Zodpey, S. Murray, C.J.L. Global Burden of Disease Cancer Collaboration

Abstract

Importance: Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting have been identified as major obstacles in achieving these goals. All of these have in common that they require information on the local cancer epidemiology. The Global Burden of Disease (GBD) study is uniquely poised to provide these crucial data. Objective: To describe cancer burden for 29 cancer groups in 195 countries from 1990 through 2017 to provide data needed for cancer control planning. Evidence Review: We used the GBD study estimation methods to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-Adjusted life-years (DALYs). Results are presented at the national level as well as by Socio-demographic Index (SDI), a composite indicator of income, educational attainment, and total fertility rate. We also analyzed the influence of the epidemiological vs the demographic transition on cancer incidence. Findings: In 2017, there were 24.5 million incident cancer cases worldwide (16.8 million without nonmelanoma skin cancer [NMSC]) and 9.6 million cancer deaths. The majority of cancer DALYs came from years of life lost (97%), and only 3% came from years lived with disability. The odds of developing cancer were the lowest in the low SDI quintile (1 in 7) and the highest in the high SDI quintile (1 in 2) for both sexes. In 2017, the most common incident cancers in men were NMSC (4.3 million incident cases); tracheal, bronchus, and lung (TBL) cancer (1.5 million incident cases); and prostate cancer (1.3 million incident cases). The most common causes of cancer deaths and DALYs for men were TBL cancer (1.3 million deaths and 28.4 million DALYs), liver cancer (572000 deaths and 15.2 million DALYs), and stomach cancer (542000 deaths and 12.2 million DALYs). For women in 2017, the most common incident cancers were NMSC (3.3 million incident cases), breast cancer (1.9 million incident cases), and colorectal cancer (819000 incident cases). The leading causes of cancer deaths and DALYs for women were breast cancer (601000 deaths and 17.4 million DALYs), TBL cancer (596000 deaths and 12.6 million DALYs), and colorectal cancer (414000 deaths and 8.3 million DALYs). Conclusions and Relevance: The national epidemiological profiles of cancer burden in the GBD study show large heterogeneities, which are a reflection of different exposures to risk factors, economic settings, lifestyles, and access to care and screening. The GBD study can be used by policy makers and other stakeholders to develop and improve national and local cancer control in order to achieve the global targets and improve equity in cancer care. © 2019 American Medical Association. All rights reserved.

Published
2019

47. Erratum: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1923–1994), (S0140673618322256), (10.1016/S0140-6736(18)32225-6))

Author

Stanaway, J.D. Afshin, A. Gakidou, E. Lim, S.S. Abate, D. Abate, K.H. Abbafati, C. Abbasi, N. Abbastabar, H. Abd-Allah, F. Abdela, J. Abdelalim, A. Abdollahpour, I. Abdulkader, R.S. Abebe, M. Abebe, Z. Abera, S.F. Abil, O.Z. Abraha, H.N. Abrham, A.R. Abu-Raddad, L.J. Abu-Rmeileh, N.M.E. Accrombessi, M.M.K. Acharya, D. Acharya, P. Adamu, A.A. Adane, A.A. Adebayo, O.M. Adedoyin, R.A. Adekanmbi, V. Ademi, Z. Adetokunboh, O.O. Adib, M.G. Admasie, A. Adsuar, J.C. Afanvi, K.A. Afarideh, M. Agarwal, G. Aggarwal, A. Aghayan, S.A. Agrawal, A. Agrawal, S. Ahmadi, A. Ahmadi, M. Ahmadieh, H. Ahmed, M.B. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akbari, M.E. Akinyemiju, T. Akseer, N. Al-Aly, Z. Al-Eyadhy, A. Al-Mekhlafi, H.M. Alahdab, F. Alam, K. Alam, S. Alam, T. Alashi, A. Alavian, S.M. Alene, K.A. Ali, K. Ali, S.M. Alijanzadeh, M. Alizadeh-Navaei, R. Aljunid, S.M. Alkerwi, A. Alla, F. Alsharif, U. Altirkawi, K. Alvis-Guzman, N. Amare, A.T. Ammar, W. Anber, N.H. Anderson, J.A. Andrei, C.L. Androudi, S. Animut, M.D. Anjomshoa, M. Ansha, M.G. Antó, J.M. Antonio, C.A.T. Anwari, P. Appiah, L.T. Appiah, S.C.Y. Arabloo, J. Aremu, O. Ärnlöv, J. Artaman, A. Aryal, K.K. Asayesh, H. Ataro, Z. Ausloos, M. Avokpaho, E.F.G.A. Awasthi, A. Ayala Quintanilla, B.P. Ayer, R. Ayuk, T.B. Azzopardi, P.S. Babazadeh, A. Badali, H. Badawi, A. Balakrishnan, K. Bali, A.G. Ball, K. Ballew, S.H. Banach, M. Banoub, J.A.M. Barac, A. Barker-Collo, S.L. Bärnighausen, T.W. Barrero, L.H. Basu, S. Baune, B.T. Bazargan-Hejazi, S. Bedi, N. Beghi, E. Behzadifar, M. Behzadifar, M. Béjot, Y. Bekele, B.B. Bekru, E.T. Belay, E. Belay, Y.A. Bell, M.L. Bello, A.K. Bennett, D.A. Bensenor, I.M. Bergeron, G. Berhane, A. Bernabe, E. Bernstein, R.S. Beuran, M. Beyranvand, T. Bhala, N. Bhalla, A. Bhattarai, S. Bhutta, Z.A. Biadgo, B. Bijani, A. Bikbov, B. Bilano, V. Bililign, N. Bin Sayeed, M.S. Bisanzio, D. Biswas, T. Bjørge, T. Blacker, B.F. Bleyer, A. Borschmann, R. Bou-Orm, I.R. Boufous, S. Bourne, R. Brady, O.J. Brauer, M. Brazinova, A. Breitborde, N.J.K. Brenner, H. Briko, A.N. Britton, G. Brugha, T. Buchbinder, R. Burnett, R.T. Busse, R. Butt, Z.A. Cahill, L.E. Cahuana-Hurtado, L. Campos-Nonato, I.R. Cárdenas, R. Carreras, G. Carrero, J.J. Carvalho, F. Castañeda-Orjuela, C.A. Castillo Rivas, J. Castro, F. Catalá-López, F. Causey, K. Cercy, K.M. Cerin, E. Chaiah, Y. Chang, H.-Y. Chang, J.-C. Chang, K.-L. Charlson, F.J. Chattopadhyay, A. Chattu, V.K. Chee, M.L. Cheng, C.-Y. Chew, A. Chiang, P.P.-C. Chimed-Ochir, O. Chin, K.L. Chitheer, A. Choi, J.-Y.J. Chowdhury, R. Christensen, H. Christopher, D.J. Chung, S.-C. Cicuttini, F.M. Cirillo, M. Cohen, A.J. Collado-Mateo, D. Cooper, C. Cooper, O.R. Coresh, J. Cornaby, L. Cortesi, P.A. Cortinovis, M. Costa, M. Cousin, E. Criqui, M.H. Cromwell, E.A. Cundiff, D.K. Daba, A.K. Dachew, B.A. Dadi, A.F. Damasceno, A.A.M. Dandona, L. Dandona, R. Darby, S.C. Dargan, P.I. Daryani, A. Das Gupta, R. Das Neves, J. Dasa, T.T. Dash, A.P. Davitoiu, D.V. Davletov, K. De la Cruz-Góngora, V. De La Hoz, F.P. De Leo, D. De Neve, J.-W. Degenhardt, L. Deiparine, S. Dellavalle, R.P. Demoz, G.T. Denova-Gutiérrez, E. Deribe, K. Dervenis, N. Deshpande, A. Des Jarlais, D.C. Dessie, G.A. Deveber, G.A. Dey, S. Dharmaratne, S.D. Dhimal, M. Dinberu, M.T. Ding, E.L. Diro, H.D. Djalalinia, S. Do, H.P. Dokova, K. Doku, D.T. Doyle, K.E. Driscoll, T.R. Dubey, M. Dubljanin, E. Duken, E.E. Duncan, B.B. Duraes, A.R. Ebert, N. Ebrahimi, H. Ebrahimpour, S. Edvardsson, D. Effiong, A. Eggen, A.E. El Bcheraoui, C. El-Khatib, Z. Elyazar, I.R. Enayati, A. Endries, A.Y. Er, B. Erskine, H.E. Eskandarieh, S. Esteghamati, A. Estep, K. Fakhim, H. Faramarzi, M. Fareed, M. Farid, T.A. Sá Farinha, C.S.E. Farioli, A. Faro, A. Farvid, M.S. Farzaei, M.H. Fatima, B. Fay, K.A. Fazaeli, A.A. Feigin, V.L. Feigl, A.B. Fereshtehnejad, S.-M. Fernandes, E. Fernandes, J.C. Ferrara, G. Ferrari, A.J. Ferreira, M.L. Filip, I. Finger, J.D. Fischer, F. Foigt, N.A. Foreman, K.J. Fukumoto, T. Fullman, N. Fürst, T. Furtado, J.M. Futran, N.D. Gall, S. Gallus, S. Gamkrelidze, A. Ganji, M. Garcia-Basteiro, A.L. Gardner, W.M. Gebre, A.K. Gebremedhin, A.T. Gebremichael, T.G. Gelano, T.F. Geleijnse, J.M. Geramo, Y.C.D. Gething, P.W. Gezae, K.E. Ghadimi, R. Ghadiri, K. Ghasemi Falavarjani, K.G. Ghasemi-Kasman, M. Ghimire, M. Ghosh, R. Ghoshal, A.G. Giampaoli, S. Gill, P.S. Gill, T.K. Gillum, R.F. Ginawi, I.A. Giussani, G. Gnedovskaya, E.V. Godwin, W.W. Goli, S. Gómez-Dantés, H. Gona, P.N. Gopalani, S.V. Goulart, A.C. Grada, A. Grams, M.E. Grosso, G. Gugnani, H.C. Guo, Y. Gupta, R. Gupta, R. Gupta, T. Gutiérrez, R.A. Gutiérrez-Torres, D.S. Haagsma, J.A. Habtewold, T.D. Hachinski, V. Hafezi-Nejad, N. Hagos, T.B. Hailegiyorgis, T.T. Hailu, G.B. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Handal, A.J. Hankey, G.J. Hao, Y. Harb, H.L. Harikrishnan, S. Haro, J.M. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hawley, C.N. Hay, S.I. Hedayatizadeh-Omran, A. Heibati, B. Heidari, B. Heidari, M. Hendrie, D. Henok, A. Heredia-Pi, I. Herteliu, C. Heydarpour, F. Heydarpour, S. Hibstu, D.T. Higazi, T.B. Hilawe, E.H. Hoek, H.W. Hoffman, H.J. Hole, M.K. Homaie Rad, E. Hoogar, P. Hosgood, H.D. Hosseini, S.M. Hosseinzadeh, M. Hostiuc, M. Hostiuc, S. Hoy, D.G. Hsairi, M. Hsiao, T. Hu, G. Hu, H. Huang, J.J. Hussen, M.A. Huynh, C.K. Iburg, K.M. Ikeda, N. Ilesanmi, O.S. Iqbal, U. Irvani, S.S.N. Irvine, C.M.S. Islam, S.M.S. Islami, F. Jackson, M.D. Jacobsen, K.H. Jahangiry, L. Jahanmehr, N. Jain, S.K. Jakovljevic, M. James, S.L. Jassal, S.K. Jayatilleke, A.U. Jeemon, P. Jha, R.P. Jha, V. Ji, J.S. Jonas, J.B. Jonnagaddala, J. Jorjoran Shushtari, Z.J. Joshi, A. Jozwiak, J.J. Jürisson, M. Kabir, Z. Kahsay, A. Kalani, R. Kanchan, T. Kant, S. Kar, C. Karami, M. Karami Matin, B.K. Karch, A. Karema, C. Karimi, N. Karimi, S.M. Kasaeian, A. Kassa, D.H. Kassa, G.M. Kassa, T.D. Kassebaum, N.J. Katikireddi, S.V. Kaul, A. Kawakami, N. Kazemi, Z. Kazemi Karyani, A. Kefale, A.T. Keiyoro, P.N. Kemp, G.R. Kengne, A.P. Keren, A. Kesavachandran, C.N. Khader, Y.S. Khafaei, B. Khafaie, M.A. Khajavi, A. Khalid, N. Khalil, I.A. Khan, G. Khan, M.S. Khan, M.A. Khang, Y.-H. Khater, M.M. Khazaei, M. Khazaie, H. Khoja, A.T. Khosravi, A. Khosravi, M.H. Kiadaliri, A.A. Kiirithio, D.N. Kim, C.-I. Kim, D. Kim, Y.-E. Kim, Y.J. Kimokoti, R.W. Kinfu, Y. Kisa, A. Kissimova-Skarbek, K. Kivimäki, M. Knibbs, L.D. Knudsen, A.K.S. Kochhar, S. Kokubo, Y. Kolola, T. Kopec, J.A. Kosen, S. Koul, P.A. Koyanagi, A. Kravchenko, M.A. Krishan, K. Krohn, K.J. Kromhout, H. Kuate Defo, B. Kucuk Bicer, B. Kumar, G.A. Kumar, M. Kuzin, I. Kyu, H.H. Lachat, C. Lad, D.P. Lad, S.D. Lafranconi, A. Lalloo, R. Lallukka, T. Lami, F.H. Lang, J.J. Lansingh, V.C. Larson, S.L. Latifi, A. Lazarus, J.V. Lee, P.H. Leigh, J. Leili, M. Leshargie, C.T. Leung, J. Levi, M. Lewycka, S. Li, S. Li, Y. Liang, J. Liang, X. Liao, Y. Liben, M.L. Lim, L.-L. Linn, S. Liu, S. Lodha, R. Logroscino, G. Lopez, A.D. Lorkowski, S. Lotufo, P.A. Lozano, R. Lucas, T.C.D. Lunevicius, R. Ma, S. Macarayan, E.R.K. Machado, Í.E. Madotto, F. Mai, H.T. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malta, D.C. Mamun, A.A. Manda, A.-L. Manguerra, H. Mansournia, M.A. Mantovani, L.G. Maravilla, J.C. Marcenes, W. Marks, A. Martin, R.V. Martins, S.C.O. Martins-Melo, F.R. März, W. Marzan, M.B. Massenburg, B.B. Mathur, M.R. Mathur, P. Matsushita, K. Maulik, P.K. Mazidi, M. McAlinden, C. McGrath, J.J. McKee, M. Mehrotra, R. Mehta, K.M. Mehta, V. Meier, T. Mekonnen, F.A. Melaku, Y.A. Melese, A. Melku, M. Memiah, P.N. Memish, Z.A. Mendoza, W. Mengistu, D.T. Mensah, G.A. Mensink, G.B.M. Mereta, S.T. Meretoja, A. Meretoja, T.J. Mestrovic, T. Mezgebe, H.B. Miazgowski, B. Miazgowski, T. Millear, A.I. Miller, T.R. Miller-Petrie, M.K. Mini, G.K. Mirarefin, M. Mirica, A. Mirrakhimov, E.M. Misganaw, A.T. Mitiku, H. Moazen, B. Mohajer, B. Mohammad, K.A. Mohammadi, M. Mohammadifard, N. Mohammadnia-Afrouzi, M. Mohammed, S. Mohebi, F. Mokdad, A.H. Molokhia, M. Momeniha, F. Monasta, L. Moodley, Y. Moradi, G. Moradi-Lakeh, M. Moradinazar, M. Moraga, P. Morawska, L. Morgado-Da-Costa, J. Morrison, S.D. Moschos, M.M. Mouodi, S. Mousavi, S.M. Mozaffarian, D. Mruts, K.B. Muche, A.A. Muchie, K.F. Mueller, U.O. Muhammed, O.S. Mukhopadhyay, S. Muller, K. Musa, K.I. Mustafa, G. Nabhan, A.F. Naghavi, M. Naheed, A. Nahvijou, A. Naik, G. Naik, N. Najafi, F. Nangia, V. Nansseu, J.R. Nascimento, B.R. Neal, B. Neamati, N. Negoi, I. Negoi, R.I. Neupane, S. Newton, C.R.J. Ngunjiri, J.W. Nguyen, A.Q. Nguyen, G. Nguyen, H.T. Nguyen, H.L.T. Nguyen, H.T. Nguyen, M. Nguyen, N.B. Nichols, E. Nie, J. Ningrum, D.N.A. Nirayo, Y.L. Nishi, N. Nixon, M.R. Nojomi, M. Nomura, S. Norheim, O.F. Noroozi, M. Norrving, B. Noubiap, J.J. Nouri, H.R. Nourollahpour Shiadeh, M. Nowroozi, M.R. Nsoesie, E.O. Nyasulu, P.S. Obermeyer, C.M. Odell, C.M. Ofori-Asenso, R. Ogbo, F.A. Oh, I.-H. Oladimeji, O. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Olsen, H.E. Olusanya, B.O. Olusanya, J.O. Ong, K.L. Ong, S.K. Oren, E. Orpana, H.M. Ortiz, A. Ota, E. Otstavnov, S.S. Øverland, S. Owolabi, M.O. Mahesh, P.A. Pacella, R. Pakhare, A.P. Pakpour, A.H. Pana, A. Panda-Jonas, S. Park, E.-K. Parry, C.D.H. Parsian, H. Patel, S. Pati, S. Patil, S.T. Patle, A. Patton, G.C. Paudel, D. Paulson, K.R. Paz Ballesteros, W.C. Pearce, N. Pereira, A. Pereira, D.M. Perico, N. Pesudovs, K. Petzold, M. Pham, H.Q. Phillips, M.R. Pillay, J.D. Piradov, M.A. Pirsaheb, M. Pischon, T. Pishgar, F. Plana-Ripoll, O. Plass, D. Polinder, S. Polkinghorne, K.R. Postma, M.J. Poulton, R. Pourshams, A. Poustchi, H. Prabhakaran, D. Prakash, S. Prasad, N. Purcell, C.A. Purwar, M.B. Qorbani, M. Radfar, A. Rafay, A. Rafiei, A. Rahim, F. Rahimi, Z. Rahimi-Movaghar, A. Rahimi-Movaghar, V. Rahman, M. Rahman, M.H.U. Rahman, M.A. Rai, R.K. Rajati, F. Rajsic, S. Raju, S.B. Ram, U. Ranabhat, C.L. Ranjan, P. Rath, G.K. Rawaf, D.L. Rawaf, S. Reddy, K.S. Rehm, C.D. Rehm, J. Reiner, R.C. Reitsma, M.B. Remuzzi, G. Renzaho, A.M.N. Resnikoff, S. Reynales-Shigematsu, L.M. Rezaei, S. Ribeiro, A.L.P. Rivera, J.A. Roba, K.T. Rodríguez-Ramírez, S. Roever, L. Román, Y. Ronfani, L. Roshandel, G. Rostami, A. Roth, G.A. Rothenbacher, D. Roy, A. Rubagotti, E. Rushton, L. Sabanayagam, C. Sachdev, P.S. Saddik, B. Sadeghi, E. Saeedi Moghaddam, S. Safari, H. Safari, Y. Safari-Faramani, R. Safdarian, M. Safi, S. Safiri, S. Sagar, R. Sahebkar, A. Sahraian, M.A. Sajadi, H.S. Salam, N. Salamati, P. Saleem, Z. Salimi, Y. Salimzadeh, H. Salomon, J.A. Salvi, D.D. Salz, I. Samy, A.M. Sanabria, J. Sanchez-Niño, M.D. Sánchez-Pimienta, T.G. Sanders, T. Sang, Y. Santomauro, D.F. Santos, I.S. Santos, J.V. Santric Milicevic, M.M. Sao Jose, B.P. Sardana, M. Sarker, A.R. Sarmiento-Suárez, R. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Sawant, A.R. Sawhney, M. Saylan, M. Sayyah, M. Schaeffner, E. Schmidt, M.I. Schneider, I.J.C. Schöttker, B. Schutte, A.E. Schwebel, D.C. Schwendicke, F. Scott, J.G. Seedat, S. Sekerija, M. Sepanlou, S.G. Serre, M.L. Serván-Mori, E. Seyedmousavi, S. Shabaninejad, H. Shaddick, G. Shafieesabet, A. Shahbazi, M. Shaheen, A.A. Shaikh, M.A. Shamah Levy, T. Shams-Beyranvand, M. Shamsi, M. Sharafi, H. Sharafi, K. Sharif, M. Sharif-Alhoseini, M. Sharifi, H. Sharma, J. Sharma, M. Sharma, R. She, J. Sheikh, A. Shi, P. Shibuya, K. Shiferaw, M.S. Shigematsu, M. Shin, M.-J. Shiri, R. Shirkoohi, R. Shiue, I. Shokraneh, F. Shoman, H. Shrime, M.G. Shupler, M.S. Si, S. Siabani, S. Sibai, A.M. Siddiqi, T.J. Sigfusdottir, I.D. Sigurvinsdottir, R. Silva, D.A.S. Silva, J.P. Silveira, D.G.A. Singh, J.A. Singh, N.P. Singh, V. Sinha, D.N. Skiadaresi, E. Skirbekk, V. Smith, D.L. Smith, M. Sobaih, B.H. Sobhani, S. Somayaji, R. Soofi, M. Sorensen, R.J.D. Soriano, J.B. Soyiri, I.N. Spinelli, A. Sposato, L.A. Sreeramareddy, C.T. Srinivasan, V. Starodubov, V.I. Steckling, N. Stein, D.J. Stein, M.B. Stevanovic, G. Stockfelt, L. Stokes, M.A. Sturua, L. Subart, M.L. Sudaryanto, A. Sufiyan, M.B. Sulo, G. Sunguya, B.F. Sur, P.J. Sykes, B.L. Szoeke, C.E.I. Tabarés-Seisdedos, R. Tabuchi, T. Tadakamadla, S.K. Takahashi, K. Tandon, N. Tassew, S.G. Tavakkoli, M. Taveira, N. Tehrani-Banihashemi, A. Tekalign, T.G. Tekelemedhin, S.W. Tekle, M.G. Temesgen, H. Temsah, M.-H. Temsah, O. Terkawi, A.S. Tessema, B. Teweldemedhin, M. Thankappan, K.R. Theis, A. Thirunavukkarasu, S. Thomas, H.J. Thomas, M.L. Thomas, N. Thurston, G.D. Tilahun, B. Tillmann, T. To, Q.G. Tobollik, M. Tonelli, M. Topor-Madry, R. Torre, A.E. Tortajada-Girbés, M. Touvier, M. Tovani-Palone, M.R. Towbin, J.A. Tran, B.X. Tran, K.B. Truelsen, T.C. Truong, N.T. Tsadik, A.G. Tudor Car, L. Tuzcu, E.M. Tymeson, H.D. Tyrovolas, S. Ukwaja, K.N. Ullah, I. Updike, R.L. Usman, M.S. Uthman, O.A. Vaduganathan, M. Vaezi, A. Valdez, P.R. Van Donkelaar, A. Varavikova, E. Varughese, S. Vasankari, T.J. Venkateswaran, V. Venketasubramanian, N. Villafaina, S. Violante, F.S. Vladimirov, S.K. Vlassov, V. Vollset, S.E. Vos, T. Vosoughi, K. Vu, G.T. Vujcic, I.S. Wagnew, F.S. Waheed, Y. Waller, S.G. Walson, J.L. Wang, Y. Wang, Y. Wang, Y.-P. Weiderpass, E. Weintraub, R.H. Weldegebreal, F. Werdecker, A. Werkneh, A.A. West, J.J. Westerman, R. Whiteford, H.A. Widecka, J. Wijeratne, T. Winkler, A.S. Wiyeh, A.B. Wiysonge, C.S. Wolfe, C.D.A. Wong, T.Y. Wu, S. Xavier, D. Xu, G. Yadgir, S. Yadollahpour, A. Yahyazadeh Jabbari, S.H. Yamada, T. Yan, L.L. Yano, Y. Yaseri, M. Yasin, Y.J. Yeshaneh, A. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. Yotebieng, M. Younis, M.Z. Yousefifard, M. Yu, C. Zaidi, Z. Zaman, S.B. Zamani, M. Zavala-Arciniega, L. Zhang, A.L. Zhang, H. Zhang, K. Zhou, M. Zimsen, S.R.M. Zodpey, S. Murray, C.J.L. GBD 2017 Risk Factor Collaborators

Abstract

Background The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk–outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improved methods, new risks and risk–outcome pairs, and new data on risk exposure levels and risk–outcome associations. Methods We used the CRA framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), by age group, sex, year, and location for 84 behavioural, environmental and occupational, and metabolic risks or groups of risks from 1990 to 2017. This study included 476 risk–outcome pairs that met the GBD study criteria for convincing or probable evidence of causation. We extracted relative risk and exposure estimates from 46 749 randomised controlled trials, cohort studies, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. Using the counterfactual scenario of theoretical minimum risk exposure level (TMREL), we estimated the portion of deaths and DALYs that could be attributed to a given risk. We explored the relationship between development and risk exposure by modelling the relationship between the Socio-demographic Index (SDI) and risk-weighted exposure prevalence and estimated expected levels of exposure and risk-attributable burden by SDI. Finally, we explored temporal changes in risk-attributable DALYs by decomposing those changes into six main component drivers of change as follows: (1) population growth; (2) changes in population age structures; (3) changes in exposure to environmental and occupational risks; (4) changes in exposure to behavioural risks; (5) changes in exposure to metabolic risks; and (6) changes due to all other factors, approximated as the risk-deleted death and DALY rates, where the risk-deleted rate is the rate that would be observed had we reduced the exposure levels to the TMREL for all risk factors included in GBD 2017. Findings In 2017, 34·1 million (95% uncertainty interval [UI] 33·3–35·0) deaths and 1·21 billion (1·14–1·28) DALYs were attributable to GBD risk factors. Globally, 61·0% (59·6–62·4) of deaths and 48·3% (46·3–50·2) of DALYs were attributed to the GBD 2017 risk factors. When ranked by risk-attributable DALYs, high systolic blood pressure (SBP) was the leading risk factor, accounting for 10·4 million (9·39–11·5) deaths and 218 million (198–237) DALYs, followed by smoking (7·10 million [6·83–7·37] deaths and 182 million [173–193] DALYs), high fasting plasma glucose (6·53 million [5·23–8·23] deaths and 171 million [144–201] DALYs), high body-mass index (BMI; 4·72 million [2·99–6·70] deaths and 148 million [98·6–202] DALYs), and short gestation for birthweight (1·43 million [1·36–1·51] deaths and 139 million [131–147] DALYs). In total, risk-attributable DALYs declined by 4·9% (3·3–6·5) between 2007 and 2017. In the absence of demographic changes (ie, population growth and ageing), changes in risk exposure and risk-deleted DALYs would have led to a 23·5% decline in DALYs during that period. Conversely, in the absence of changes in risk exposure and risk-deleted DALYs, demographic changes would have led to an 18·6% increase in DALYs during that period. The ratios of observed risk exposure levels to exposure levels expected based on SDI (O/E ratios) increased globally for unsafe drinking water and household air pollution between 1990 and 2017. This result suggests that development is occurring more rapidly than are changes in the underlying risk structure in a population. Conversely, nearly universal declines in O/E ratios for smoking and alcohol use indicate that, for a given SDI, exposure to these risks is declining. In 2017, the leading Level 4 risk factor for age-standardised DALY rates was high SBP in four super-regions: central Europe, eastern Europe, and central Asia; north Africa and Middle East; south Asia; and southeast Asia, east Asia, and Oceania. The leading risk factor in the high-income super-region was smoking, in Latin America and Caribbean was high BMI, and in sub-Saharan Africa was unsafe sex. O/E ratios for unsafe sex in sub-Saharan Africa were notably high, and those for alcohol use in north Africa and the Middle East were notably low. Interpretation By quantifying levels and trends in exposures to risk factors and the resulting disease burden, this assessment offers insight into where past policy and programme efforts might have been successful and highlights current priorities for public health action. Decreases in behavioural, environmental, and occupational risks have largely offset the effects of population growth and ageing, in relation to trends in absolute burden. Conversely, the combination of increasing metabolic risks and population ageing will probably continue to drive the increasing trends in non-communicable diseases at the global level, which presents both a public health challenge and opportunity. We see considerable spatiotemporal heterogeneity in levels of risk exposure and risk-attributable burden. Although levels of development underlie some of this heterogeneity, O/E ratios show risks for which countries are overperforming or underperforming relative to their level of development. As such, these ratios provide a benchmarking tool to help to focus local decision making. Our findings reinforce the importance of both risk exposure monitoring and epidemiological research to assess causal connections between risks and health outcomes, and they highlight the usefulness of the GBD study in synthesising data to draw comprehensive and robust conclusions that help to inform good policy and strategic health planning. Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.

Published
2019

48. Burden of injury along the development spectrum: Associations between the Socio-demographic Index and disability-adjusted life year estimates from the Global Burden of Disease Study 2017

Author

Haagsma, J.A. James, S.L. Castle, C.D. Dingels, Z.V. Fox, J.T. Hamilton, E.B. Liu, Z. Lucchesi, L.R. Roberts, N.L.S. Sylte, D.O. Adebayo, O.M. Ahmadi, A. Ahmed, M.B. Aichour, M.T.E. Alahdab, F. Alghnam, S.A. Aljunid, S.M. Al-Raddadi, R.M. Alsharif, U. Altirkawi, K. Anjomshoa, M. Antonio, C.A.T. Appiah, S.C.Y. Aremu, O. Arora, A. Asayesh, H. Assadi, R. Awasthi, A. Ayala Quintanilla, B.P. Balalla, S. Banstola, A. Barker-Collo, S.L. Bärnighausen, T.W. Bazargan-Hejazi, S. Bedi, N. Behzadifar, M. Behzadifar, M. Benjet, C. Bennett, D.A. Bensenor, I.M. Bhaumik, S. Bhutta, Z.A. Bijani, A. Borges, G. Borschmann, R. Bose, D. Boufous, S. Brazinova, A. Campuzano Rincon, J.C. Cárdenas, R. Carrero, J.J. Carvalho, F. Castañeda-Orjuela, C.A. Catalá-López, F. Choi, J.-Y.J. Christopher, D.J. Crowe, C.S. Dalal, K. Daryani, A. Davitoiu, D.V. Degenhardt, L. De Leo, D. De Neve, J.-W. Deribe, K. Dessie, G.A. Deveber, G.A. Dharmaratne, S.D. Doan, L.P. Dolan, K.A. Driscoll, T.R. Dubey, M. El-Khatib, Z. Ellingsen, C.L. El Sayed Zaki, M. Endries, A.Y. Eskandarieh, S. Faro, A. Fereshtehnejad, S.-M. Fernandes, E. Filip, I. Fischer, F. Franklin, R.C. Fukumoto, T. Gezae, K.E. Gill, T.K. Goulart, A.C. Grada, A. Guo, Y. Gupta, R. Haghparast Bidgoli, H. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Haro, J.M. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hendrie, D. Henok, A. Híjar, M. Hole, M.K. Homaie Rad, E. Hossain, N. Hostiuc, S. Hu, G. Igumbor, E.U. Ilesanmi, O.S. Irvani, S.S.N. Islam, S.M.S. Ivers, R.Q. Jacobsen, K.H. Jahanmehr, N. Jakovljevic, M. Jayatilleke, A.U. Jha, R.P. Jonas, J.B. Jorjoran Shushtari, Z. Jozwiak, J.J. Jürisson, M. Kabir, A. Kalani, R. Kasaeian, A. Kelbore, A.G. Kengne, A.P. Khader, Y.S. Khafaie, M.A. Khalid, N. Khan, E.A. Khoja, A.T. Kiadaliri, A.A. Kim, Y.-E. Kim, D. Kisa, A. Koyanagi, A. Kuate Defo, B. Kucuk Bicer, B. Kumar, M. Lalloo, R. Lam, H. Lami, F.H. Lansingh, V.C. Leasher, J.L. Li, S. Linn, S. Lunevicius, R. MacHado, F.R. Magdy Abd El Razek, H. Magdy Abd El Razek, M. Mahotra, N.B. Majdan, M. Majeed, A. Malekzadeh, R. Malik, M.A. Malta, D.C. Manda, A.-L. Mansournia, M.A. Massenburg, B.B. Maulik, P.K. Meheretu, H.A.A. Mehndiratta, M.M. Melese, A. Mendoza, W. Mengesha, M.M. Meretoja, T.J. Meretoja, A. Mestrovic, T. Miazgowski, T. Miller, T.R. Mini, G.K. Mirrakhimov, E.M. Moazen, B. Mohammad Gholi Mezerji, N. Mohammadibakhsh, R. Mohammed, S. Molokhia, M. Monasta, L. Mondello, S. Montero-Zamora, P.A. Moodley, Y. Moosazadeh, M. Moradi, G. Moradi-Lakeh, M. Morawska, L. Velásquez, I.M. Morrison, S.D. Moschos, M.M. Mousavi, S.M. Murthy, S. Musa, K.I. Naik, G. Najafi, F. Nangia, V. Nascimento, B.R. Ndwandwe, D.E. Negoi, I. Nguyen, T.H. Nguyen, S.H. Nguyen, L.H. Nguyen, H.L.T. Ningrum, D.N.A. Nirayo, Y.L. Ofori-Asenso, R. Ogbo, F.A. Oh, I.-H. Oladimeji, O. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Orpana, H.M. Otstavnov, S.S. Mahesh, P.A. Pakhale, S. Park, E.-K. Patton, G.C. Pesudovs, K. Phillips, M.R. Polinder, S. Prakash, S. Radfar, A. Rafay, A. Rafiei, A. Rahimi, S. Rahimi-Movaghar, V. Rahman, M.A. Rai, R.K. Ramezanzadeh, K. Rawaf, S. Rawaf, D.L. Renzaho, A.M.N. Resnikoff, S. Rezaeian, S. Roever, L. Ronfani, L. Roshandel, G. Sabde, Y.D. Saddik, B. Salamati, P. Salimi, Y. Salz, I. Samy, A.M. Sanabria, J. Sanchez Riera, L. Santric Milicevic, M.M. Satpathy, M. Sawhney, M. Sawyer, S.M. Saxena, S. Saylan, M. Schneider, I.J.C. Schwebel, D.C. Seedat, S. Sepanlou, S.G. Shaikh, M.A. Shams-Beyranvand, M. Shamsizadeh, M. Sharif-Alhoseini, M. Sheikh, A. Shen, J. Shigematsu, M. Shiri, R. Shiue, I. Silva, J.P. Singh, J.A. Sinha, D.N. Soares Filho, A.M. Soriano, J.B. Soshnikov, S. Soyiri, I.N. Starodubov, V.I. Stein, D.J. Stokes, M.A. Sufiyan, M.B. Sunshine, J.E. Sykes, B.L. Tabarés-Seisdedos, R. Tabb, K.M. Tehrani-Banihashemi, A. Tessema, G.A. Thakur, J.S. Tran, K.B. Tran, B.X. Tudor Car, L. Uthman, O.A. Uzochukwu, B.S.C. Valdez, P.R. Varavikova, E. Vasconcelos, A.M.N. Venketasubramanian, N. Violante, F.S. Vlassov, V. Waheed, Y. Wang, Y.-P. Wijeratne, T. Winkler, A.S. Yadav, P. Yano, Y. Yenesew, M.A. Yip, P. Yisma, E. Yonemoto, N. Younis, M.Z. Yu, C. Zafar, S. Zaidi, Z. Zaman, S.B. Zamani, M. Zhao, Y. Zodpey, S. Hay, S.I. Lopez, A.D. Mokdad, A.H. Vos, T.

Abstract

Background: The epidemiological transition of non-communicable diseases replacing infectious diseases as the main contributors to disease burden has been well documented in global health literature. Less focus, however, has been given to the relationship between sociodemographic changes and injury. The aim of this study was to examine the association between disability-adjusted life years (DALYs) from injury for 195 countries and territories at different levels along the development spectrum between 1990 and 2017 based on the Global Burden of Disease (GBD) 2017 estimates. Methods: Injury mortality was estimated using the GBD mortality database, corrections for garbage coding and CODEm-the cause of death ensemble modelling tool. Morbidity estimation was based on surveys and inpatient and outpatient data sets for 30 cause-of-injury with 47 nature-of-injury categories each. The Socio-demographic Index (SDI) is a composite indicator that includes lagged income per capita, average educational attainment over age 15 years and total fertility rate. Results: For many causes of injury, age-standardised DALY rates declined with increasing SDI, although road injury, interpersonal violence and self-harm did not follow this pattern. Particularly for self-harm opposing patterns were observed in regions with similar SDI levels. For road injuries, this effect was less pronounced. Conclusions: The overall global pattern is that of declining injury burden with increasing SDI. However, not all injuries follow this pattern, which suggests multiple underlying mechanisms influencing injury DALYs. There is a need for a detailed understanding of these patterns to help to inform national and global efforts to address injury-related health outcomes across the development spectrum. © 2020 Author(s).

Published
2019

49. Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016

Author

James, S.L. Bannick, M.S. Montjoy-Venning, W.C. Lucchesi, L.R. Dandona, L. Dandona, R. Hawley, C. Hay, S.I. Jakovljevic, M. Khalil, I. Krohn, K.J. Mokdad, A.H. Naghavi, M. Nichols, E. Reiner, R.C. Smith, M. Feigin, V.L. Vos, T. Murray, C.J.L. Sunshine, J.E. Yost, M.G. Ellenbogen, R.G. Kalani, R. Morrison, S.D. Crowe, C.S. Massenburg, B.B. Theadom, A. Te Ao, B.J. Balalla, S. Jones, K.M. Ofori-Asenso, R. Li, S. Sobhani, S. Hosseini, S.M. Mansournia, M.A. Yaseri, M. Anjomshoa, M. Mousavi, S.M. Haj-Mirzaian, A. Haj-Mirzaian, A. Malekzadeh, R. Poustchi, H. Roshandel, G. Sepanlou, S.G. Afarideh, M. Esteghamati, A. Esteghamati, S. Ganji, M. Kasaeian, A. Rahimi-Movaghar, A. Eskandarieh, S. Sahraian, M.A. Shams-Beyranvand, M. Abbasi, N. Farzadfar, F. Irvani, S.N. Rahimi-Movaghar, V. Salamati, P. Sharif-Alhoseini, M. Fereshtehnejad, S.-M. Mate, K.K.V. Abdulkader, R. Abraha, H.N. Kassa, T.D. Nirayo, Y.L. Weldegwergs, K.G. Gezae, K.E. Zenebe, Z.M. Degefa, M.G. Kahsay, A. Asgedom, S.W. Gebre, A.K. Yimer, E.M. Belachew, A.B. Meles, H. Adsuar, J.C. Zodpey, S. Agrawal, S. Awasthi, A. Kumar, G.A. Ahmadi, A. Najafi, F. Rajati, F. Khazaie, H. Farzaei, M.H. Moradi, M. Rezaei, S. Soofi, M. Siabani, S. Rezaeian, S. Ahmed, M.B. Gebrehiwot, T.T. Feyissa, G.T. Hussen, M.A. Aichour, A. Aichour, I. Aichour, M.T.E. Akinyemi, R.O. Owolabi, M.O. Akseer, N. Bhutta, Z.A. Badawi, A. Alahdab, F. Kassa, G.M. Alebel, A. Wagnew, F.W.S. Belay, Y.A. Leshargie, C.T. Alghnam, S.A. Ali, B.A. Alsharif, U. Temsah, M.-H. Altirkawi, K. Davitoiu, D.V. Hostiuc, S. Beuran, M. Negoi, I. Andrei, C.L. Ansari, H. Ansha, M.G. Antonio, C.A.T. Appiah, S.C.Y. Levi, M. Ariani, F. Biffino, M. Asefa, N.G. Atique, S. Rahman, M.A. Wijeratne, T. Ayala Quintanilla, B.P. Ayuk, T.B. Azzopardi, P.S. Rafiei, A. Badali, H. Mohammadi, M. Moosazadeh, M. Daryani, A. Banstola, A. Tran, K.B. Barker-Collo, S.L. Bärnighausen, T.W. Bedi, N. Tehrani-Banihashemi, A. Shabaninejad, H. Behzadifar, Ma. Kabir, A. Yousefifard, M. Moradi-Lakeh, M. Behzadifar, Me. Bekele, B. Hassen, H.Y. Henok, A. Biadgo, B. Bennett, D.A. Goulart, A.C. Bensenor, I.M. Lotufo, P.A. Wang, Y.P. Yisma, E. Berhane, A. Deribe, K. Yasin, Y.J. Demoz, G.T. Bhalla, A. Bhaumik, S. Bijani, A. Zamani, M. Bililign, N. Kumar, M. Birungi, C. Boufous, S. Brazinova, A. Brown, A.W. Car, M. Majeed, A. Rawaf, S. Rawaf, D.L. Shoman, H. Cárdenas, R. Carrero, J.J. El-Khatib, Z. Roy, N. Carvalho, F. Santos, J.V. Fernandes, E. Silva, J.P. Castañeda-Orjuela, C.A. Hoffman, H.J. Catalá-López, F. Chaiah, Y. Temsah, O. Champs, A.P. Chang, J.-C. Choi, J.-Y.J. Christopher, D.J. Cooper, C. Djalalinia, S. Do, H.P. Nguyen, T.H. Doku, D.T. Drake, T.M. Sheikh, A. Soyiri, I.N. Dubey, M. Santric Milicevic, M.M.M. Dubljanin, E. Faro, A. Filip, I. Radfar, A. Fischer, F. Fukumoto, T. Gankpe, F.G. Gopalkrishna, G. Haagsma, J.A. Polinder, S. Khoja, A.T. Pinilla-Monsalve, G.D. Hamadeh, R.R. Hamidi, S. Haro, J.M. Hassankhani, H. Havmoeller, R. Hegazy, M.I. Hendrie, D. Miller, T.R. Hibstu, D.T. Kassa, Z.Y. Hole, M.K. Homaie Rad, E. Hu, G. Ilesanmi, O.S. Jayaraman, S. Jha, R.P. Jonas, J.B. Moazen, B. Jorjoran Shushtari, Z. Jozwiak, J.J. Jürisson, M. Kahssay, M. Liben, M.L. Karch, A. Kengne, A.P. Khader, Y.S. Safari, H. Khafaie, M.A. Khalid, N. Khan, E.A. Khan, M.S. Usman, M.S. Siddiqi, T.J. Khang, Y.-H. Khubchandani, J. Kiadaliri, A.A. Kim, D. Kim, Y.-E. Yoon, S.-J. Kisa, A. Winkler, A.S. Koyanagi, A. Kuate Defo, B. Kucuk Bicer, B. Lalloo, R. Moradinazar, M. Lami, F.H. Lansingh, V.C. Laryea, D.O. Latifi, A. Safiri, S. Lunevicius, R. Mahotra, N.B. Majdan, M. Manda, A.-L. Mehndiratta, M.M. Mehta, V. Melese, A. Memiah, P.T.N. Mendoza, W. Mengistu, G. Shiferaw, M.S. Tekle, M.G. Meretoja, T.J. Meretoja, A. Szoeke, C.E.I. Mestrovich, T. Miazgowski, T. Mini, G.K. Mirica, A. Mirrakhimov, E.M. Molokhia, M. Monast, L. Ronfani, L. Mondello, S. Moradi, G. Moschos, M.M. Murthy, S. Musa, K.I. Mustafa, G. Naik, G. Schwebel, D.C. Nangia, V. Nascimento, B.R. Ningrum, D.N.A. Nyasulu, P.S. Renzaho, A.M.N. Ogbo, F.A. Oh, I.-H. Okoro, A. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Otstavnov, S.S. Dnb, M.P.A. Pakhale, S. Pandey, A.R. Pesudovs, K. Prakash, S. Qorbani, M. Rafay, A. Rahman, M. Stokes, M.A. Shariful Islam, S.M. Rai, R.K. Ram, U. Reis, C. Resnikoff, S. Roever, L. Sunguy, B.F. Ruhago, G.M. Saddik, B. Saldanha, R.D.F. Samy, A.M. Sanabria, J. Sartorius, B. Satpathy, M. Schneider, I.J.C. Shaikh, M.A.A. Sharif, M. She, J. Shen, J. Sheth, K.N. Shibuya, K. Shigematsu, M. Shiri, R. Shiue, I. Silveira, D.A. Soares Filho, A.M. Sinha, D.N. Soriano, J.B. Stein, D.J. Sufiyan, M.B. Sykes, B.L. Tabarés-Seisdedos, R. Tortajada-Girbés, M. Topor-Madry, R. Tran, B.X. Tudor Car, L. Ukwaja, K.N. Ullah, I. Uthman, O.A. Valdez, P.R. Vasankari, T.J. Venketasubramanian, N. Violante, F.S. Waheed, Y. Werdecker, A. Wyper, G.M.A. Yano, Y. Ye, P. Yip, P. Yonemoto, N. Younis, M.Z. Yu, C. Zaidi, Z. Zaman, S.B. GBD 2016 Traumatic Brain Injury Spinal Cord Injury Collaborators

Abstract

Background Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly recognised as global health priorities in view of the preventability of most injuries and the complex and expensive medical care they necessitate. We aimed to measure the incidence, prevalence, and years of life lived with disability (YLDs) for TBI and SCI from all causes of injury in every country, to describe how these measures have changed between 1990 and 2016, and to estimate the proportion of TBI and SCI cases caused by different types of injury. Methods We used results from the Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016 to measure the global, regional, and national burden of TBI and SCI by age and sex. We measured the incidence and prevalence of all causes of injury requiring medical care in inpatient and outpatient records, literature studies, and survey data. By use of clinical record data, we estimated the proportion of each cause of injury that required medical care that would result in TBI or SCI being considered as the nature of injury. We used literature studies to establish standardised mortality ratios and applied differential equations to convert incidence to prevalence of long-term disability. Finally, we applied GBD disability weights to calculate YLDs. We used a Bayesian meta-regression tool for epidemiological modelling, used causespecific mortality rates for non-fatal estimation, and adjusted our results for disability experienced with comorbid conditions. We also analysed results on the basis of the Socio-demographic Index, a compound measure of income per capita, education, and fertility. Findings In 2016, there were 27.08 million (95% uncertainty interval [UI] 24.30-30.30 million) new cases of TBI and 0.93 million (0.78-1.16 million) new cases of SCI, with age-standardised incidence rates of 369 (331-412) per 100 000 population for TBI and 13 (11-16) per 100 000 for SCI. In 2016, the number of prevalent cases of TBI was 55.50 million (53.40-57.62 million) and of SCI was 27.04 million (24.98-30.15 million). From 1990 to 2016, the agestandardised prevalence of TBI increased by 8.4% (95% UI 7.7 to 9.2), whereas that of SCI did not change significantly (-0.2% [-2.1 to 2.7]). Age-standardised incidence rates increased by 3.6% (1.8 to 5.5) for TBI, but did not change significantly for SCI (-3.6% [-7.4 to 4.0]). TBI caused 8.1 million (95% UI 6.0-10.4 million) YLDs and SCI caused 9.5 million (6.7-12.4 million) YLDs in 2016, corresponding to age-standardised rates of 111 (82-141) per 100 000 for TBI and 130 (90-170) per 100 000 for SCI. Falls and road injuries were the leading causes of new cases of TBI and SCI in most regions. Interpretation TBI and SCI constitute a considerable portion of the global injury burden and are caused primarily by falls and road injuries. The increase in incidence of TBI over time might continue in view of increases in population density, population ageing, and increasing use of motor vehicles, motorcycles, and bicycles. The number of individuals living with SCI is expected to increase in view of population growth, which is concerning because of the specialised care that people with SCI can require. Our study was limited by data sparsity in some regions, and it will be important to invest greater resources in collection of data for TBI and SCI to improve the accuracy of future assessments. © 2018 The Author(s).

Published
2019

50. Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Author

Feigin, V.L. Nichols, E. Alam, T. Bannick, M.S. Beghi, E. Blake, N. Culpepper, W.J. Dorsey, E.R. Elbaz, A. Ellenbogen, R.G. Fisher, J.L. Fitzmaurice, C. Giussani, G. Glennie, L. James, S.L. Johnson, C.O. Kassebaum, N.J. Logroscino, G. Marin, B. Mountjoy-Venning, W.C. Nguyen, M. Ofori-Asenso, R. Patel, A.P. Piccininni, M. Roth, G.A. Steiner, T.J. Stovner, L.J. Szoeke, C.E.I. Theadom, A. Vollset, S.E. Wallin, M.T. Wright, C. Zunt, J.R. Abbasi, N. Abd-Allah, F. Abdelalim, A. Abdollahpour, I. Aboyans, V. Abraha, H.N. Acharya, D. Adamu, A.A. Adebayo, O.M. Adeoye, A.M. Adsuar, J.C. Afarideh, M. Agrawal, S. Ahmadi, A. Ahmed, M.B. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akinyemi, R.O. Akseer, N. Al-Eyadhy, A. Al-Shahi Salman, R. Alahdab, F. Alene, K.A. Aljunid, S.M. Altirkawi, K. Alvis-Guzman, N. Anber, N.H. Antonio, C.A.T. Arabloo, J. Aremu, O. Ärnlöv, J. Asayesh, H. Asghar, R.J. Atalay, H.T. Awasthi, A. Ayala Quintanilla, B.P. Ayuk, T.B. Badawi, A. Banach, M. Banoub, J.A.M. Barboza, M.A. Barker-Collo, S.L. Bärnighausen, T.W. Baune, B.T. Bedi, N. Behzadifar, M. Behzadifar, M. Béjot, Y. Bekele, B.B. Belachew, A.B. Bennett, D.A. Bensenor, I.M. Berhane, A. Beuran, M. Bhattacharyya, K. Bhutta, Z.A. Biadgo, B. Bijani, A. Bililign, N. Bin Sayeed, M.S. Blazes, C.K. Brayne, C. Butt, Z.A. Campos-Nonato, I.R. Cantu-Brito, C. Car, M. Cárdenas, R. Carrero, J.J. Carvalho, F. Castañeda-Orjuela, C.A. Castro, F. Catalá-López, F. Cerin, E. Chaiah, Y. Chang, J.-C. Chatziralli, I. Chiang, P.P.-C. Christensen, H. Christopher, D.J. Cooper, C. Cortesi, P.A. Costa, V.M. Criqui, M.H. Crowe, C.S. Damasceno, A.A.M. Daryani, A. De la Cruz-Góngora, V. De La Hoz, F.P. De Leo, D. Degefa, M.G. Demoz, G.T. Deribe, K. Dharmaratne, S.D. Diaz, D. Dinberu, M.T. Djalalinia, S. Doku, D.T. Dubey, M. Dubljanin, E. Duken, E.E. Edvardsson, D. El-Khatib, Z. Endres, M. Endries, A.Y. Eskandarieh, S. Esteghamati, A. Esteghamati, S. Farhadi, F. Faro, A. Farzadfar, F. Farzaei, M.H. Fatima, B. Fereshtehnejad, S.-M. Fernandes, E. Feyissa, G.T. Filip, I. Fischer, F. Fukumoto, T. Ganji, M. Gankpe, F.G. Garcia-Gordillo, M.A. Gebre, A.K. Gebremichael, T.G. Gelaw, B.K. Geleijnse, J.M. Geremew, D. Gezae, K.E. Ghasemi-Kasman, M. Gidey, M.Y. Gill, P.S. Gill, T.K. Gnedovskaya, E.V. Goulart, A.C. Grada, A. Grosso, G. Guo, Y. Gupta, R. Gupta, R. Haagsma, J.A. Hagos, T.B. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Hankey, G.J. Hao, Y. Haro, J.M. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hay, S.I. Hegazy, M.I. Heidari, B. Henok, A. Heydarpour, F. Hoang, C.L. Hole, M.K. Homaie Rad, E. Hosseini, S.M. Hu, G. Igumbor, E.U. Ilesanmi, O.S. Irvani, S.S.N. Islam, S.M.S. Jakovljevic, M. Javanbakht, M. Jha, R.P. Jobanputra, Y.B. Jonas, J.B. Józwiak, J.J. Jürisson, M. Kahsay, A. Kalani, R. Kalkonde, Y. Kamil, T.A. Kanchan, T. Karami, M. Karch, A. Karimi, N. Kasaeian, A. Kassa, T.D. Kassa, Z.Y. Kaul, A. Kefale, A.T. Keiyoro, P.N. Khader, Y.S. Khafaie, M.A. Khalil, I.A. Khan, E.A. Khang, Y.-H. Khazaie, H. Kiadaliri, A.A. Kiirithio, D.N. Kim, A.S. Kim, D. Kim, Y.-E. Kim, Y.J. Kisa, A. Kokubo, Y. Koyanagi, A. Krishnamurthi, R.V. Kuate Defo, B. Kucuk Bicer, B. Kumar, M. Lacey, B. Lafranconi, A. Lansingh, V.C. Latifi, A. Leshargie, C.T. Li, S. Liao, Y. Linn, S. Lo, W.D. Lopez, J.C.F. Lorkowski, S. Lotufo, P.A. Lucas, R.M. Lunevicius, R. Mackay, M.T. Mahotra, N.B. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malta, D.C. Manafi, N. Mansournia, M.A. Mantovani, L.G. März, W. Mashamba-Thompson, T.P. Massenburg, B.B. Mate, K.K.V. McAlinden, C. McGrath, J.J. Mehta, V. Meier, T. Meles, H.G. Melese, A. Memiah, P.T.N. Memish, Z.A. Mendoza, W. Mengistu, D.T. Mengistu, G. Meretoja, A. Meretoja, T.J. Mestrovic, T. Miazgowski, B. Miazgowski, T. Miller, T.R. Mini, G.K. Mirrakhimov, E.M. Moazen, B. Mohajer, B. Mohammad Gholi Mezerji, N. Mohammadi, M. Mohammadi-Khanaposhtani, M. Mohammadibakhsh, R. Mohammadnia-Afrouzi, M. Mohammed, S. Mohebi, F. Mokdad, A.H. Monasta, L. Mondello, S. Moodley, Y. Moosazadeh, M. Moradi, G. Moradi-Lakeh, M. Moradinazar, M. Moraga, P. Moreno Velásquez, I. Morrison, S.D. Mousavi, S.M. Muhammed, O.S. Muruet, W. Musa, K.I. Mustafa, G. Naderi, M. Nagel, G. Naheed, A. Naik, G. Najafi, F. Nangia, V. Negoi, I. Negoi, R.I. Newton, C.R.J. Ngunjiri, J.W. Nguyen, C.T. Nguyen, L.H. Ningrum, D.N.A. Nirayo, Y.L. Nixon, M.R. Norrving, B. Noubiap, J.J. Nourollahpour Shiadeh, M. Nyasulu, P.S. Ogbo, F.A. Oh, I.-H. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Onwujekwe, O.E. Oren, E. Owolabi, M.O. A, M.P. Pakpour, A.H. Pan, W.-H. Panda-Jonas, S. Pandian, J.D. Patel, S.K. Pereira, D.M. Petzold, M. Pillay, J.D. Piradov, M.A. Polanczyk, G.V. Polinder, S. Postma, M.J. Poulton, R. Poustchi, H. Prakash, S. Prakash, V. Qorbani, M. Radfar, A. Rafay, A. Rafiei, A. Rahim, F. Rahimi-Movaghar, V. Rahman, M. Rahman, M.H.U. Rahman, M.A. Rajati, F. Ram, U. Ranta, A. Rawaf, D.L. Rawaf, S. Reinig, N. Reis, C. Renzaho, A.M.N. Resnikoff, S. Rezaeian, S. Rezai, M.S. Rios González, C.M. Roberts, N.L.S. Roever, L. Ronfani, L. Roro, E.M. Roshandel, G. Rostami, A. Sabbagh, P. Sacco, R.L. Sachdev, P.S. Saddik, B. Safari, H. Safari-Faramani, R. Safi, S. Safiri, S. Sagar, R. Sahathevan, R. Sahebkar, A. Sahraian, M.A. Salamati, P. Salehi Zahabi, S. Salimi, Y. Samy, A.M. Sanabria, J. Santos, I.S. Santric Milicevic, M.M. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Sawant, A.R. Sawhney, M. Schneider, I.J.C. Schöttker, B. Schwebel, D.C. Seedat, S. Sepanlou, S.G. Shabaninejad, H. Shafieesabet, A. Shaikh, M.A. Shakir, R.A. Shams-Beyranvand, M. Shamsizadeh, M. Sharif, M. Sharif-Alhoseini, M. She, J. Sheikh, A. Sheth, K.N. Shigematsu, M. Shiri, R. Shirkoohi, R. Shiue, I. Siabani, S. Siddiqi, T.J. Sigfusdottir, I.D. Sigurvinsdottir, R. Silberberg, D.H. Silva, J.P. Silveira, D.G.A. Singh, J.A. Sinha, D.N. Skiadaresi, E. Smith, M. Sobaih, B.H. Sobhani, S. Soofi, M. Soyiri, I.N. Sposato, L.A. Stein, D.J. Stein, M.B. Stokes, M.A. Sufiyan, M.B. Sykes, B.L. Sylaja, P. Tabarés-Seisdedos, R. Te Ao, B.J. Tehrani-Banihashemi, A. Temsah, M.-H. Temsah, O. Thakur, J.S. Thrift, A.G. Topor-Madry, R. Tortajada-Girbés, M. Tovani-Palone, M.R. Tran, B.X. Tran, K.B. Truelsen, T.C. Tsadik, A.G. Tudor Car, L. Ukwaja, K.N. Ullah, I. Usman, M.S. Uthman, O.A. Valdez, P.R. Vasankari, T.J. Vasanthan, R. Veisani, Y. Venketasubramanian, N. Violante, F.S. Vlassov, V. Vosoughi, K. Vu, G.T. Vujcic, I.S. Wagnew, F.S. Waheed, Y. Wang, Y.-P. Weiderpass, E. Weiss, J. Whiteford, H.A. Wijeratne, T. Winkler, A.S. Wiysonge, C.S. Wolfe, C.D.A. Xu, G. Yadollahpour, A. Yamada, T. Yano, Y. Yaseri, M. Yatsuya, H. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yousefifard, M. Yu, C. Zaidi, Z. Zaman, S.B. Zamani, M. Zandian, H. Zare, Z. Zhang, Y. Zodpey, S. Naghavi, M. Murray, C.J.L. Vos, T. GBD 2016 Neurology Collaborators

Abstract

Background: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders. Methods: We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach. Findings: Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247–308]) and second leading cause of deaths (9·0 million [8·8–9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34–44] and DALYs by 15% [9–21]) whereas their age-standardised rates decreased (deaths by 28% [26–30] and DALYs by 27% [24–31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6–46·1]), migraine (16·3% [11·7–20·8]), Alzheimer's and other dementias (10·4% [9·0–12·1]), and meningitis (7·9% [6·6–10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05–1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burdens, except stroke, for which 88·8% (86·5–90·9) of DALYs are attributable to risk factors, and to a lesser extent Alzheimer's disease and other dementias (22·3% [11·8–35·1] of DALYs are risk attributable) and idiopathic epilepsy (14·1% [10·8–17·5] of DALYs are risk attributable). Interpretation: Globally, the burden of neurological disorders, as measured by the absolute number of DALYs, continues to increase. As populations are growing and ageing, and the prevalence of major disabling neurological disorders steeply increases with age, governments will face increasing demand for treatment, rehabilitation, and support services for neurological disorders. The scarcity of established modifiable risks for most of the neurological burden demonstrates that new knowledge is required to develop effective prevention and treatment strategies. Funding: Bill & Melinda Gates Foundation. © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license

Published
2019

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