1. Regression of venous thrombus after trans‐sphenoidal hypophysectomy for pituitary‐dependent hyperadrenocorticism in a dog.
- Author
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Tanaka, S., Suzuki, S., Teshima, T., Yamashita, R., Hamamoto, Y., and Hara, Y.
- Subjects
THROMBOSIS ,PORTAL vein ,FIBRINOLYTIC agents ,LIVER ,DOGS ,BLOOD coagulation - Abstract
An 8.0‐kg 8‐year‐old male dachshund was presented for surgical treatment of suspected pituitary‐dependent hyperadrenocorticism with portal vein thrombosis. Advanced diagnostic imaging revealed a thrombus in the splenic and portal veins. For the portal vein thrombus, CT angiography showed an enhanced timing delay in the lateral right and caudate liver lobes. Blood tests showed a marked increase in the liver panel, including total bile acid. Brain MRI revealed a pituitary mass, suggesting pituitary‐dependent hyperadrenocorticism. The mass was completely resected. The preoperative antithrombotic therapy of rivaroxaban (0.66 mg/kg, PO, once per day) and clopidogrel sulphate (1.66 mg/kg, PO, once per day) was continued postoperatively. Six months after resection of the pituitary mass, the thrombus had disappeared. Further studies are required to prove a causal association between the disappearance of the thrombus and the treatments provided. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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