Search

α-Chiral allylic amines are prepared by highly regio- and enantioselective hydroamination of various allenes applying a rhodium(I)/Josiphos catalyst. [ABSTRACT FROM AUTHOR]

The scalable method represents the first coupling of aryl tetrazoles with mono and 1,1-disubstituted allenes. [ABSTRACT FROM AUTHOR]

An abstract of the article "Regio- and Enantioselective Synthesis of N-Substituted Pyrazoles by Rhodium-Catalyzed Asymmetric Addition to Allenes" by A. M. Haydl and colleagues is presented.

The title reaction affords both chiral branched and achiral linear products in dependance on the conditions used. [ABSTRACT FROM AUTHOR]

It is found that the Cu(I/II)-catalyzed addition of nitro esters to unsaturated α-ketoesters can be performed in good yields with high enantioselectivity. [ABSTRACT FROM AUTHOR]

The described transformations can be performed with comparable results on a gram scale. [ABSTRACT FROM AUTHOR]

Optimized conditions allow the preparation of α-chiral allylic amines as important synthons in organic chemistry. [ABSTRACT FROM AUTHOR]

In course of this study the reaction is also conducted in water for the first time. [ABSTRACT FROM AUTHOR]

N-Methyl pyrrole, furan and thiophene do not react with (Ia). [ABSTRACT FROM AUTHOR]