72 results on '"Graff JC"'
Search Results
2. Association between population density and infection rate suggests the importance of social distancing and travel restriction in reducing the COVID-19 pandemic.
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Yin H, Sun T, Yao L, Jiao Y, Ma L, Lin L, Graff JC, Aleya L, Postlethwaite A, Gu W, and Chen H
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- China epidemiology, Humans, Physical Distancing, Population Density, SARS-CoV-2, COVID-19, Pandemics
- Abstract
Currently, 2019-nCoV has spread to most countries of the world. Understanding the environmental factors that affect the spread of the disease COVID-19 infection is critical to stop the spread of the disease. The purpose of this study is to investigate whether population density is associated with the infection rate of the COVID-19. We collected data from official webpages of cities in China and in the USA. The data were organized on Excel spreadsheets for statistical analyses. We calculated the morbidity and population density of cities and regions in these two countries. We then examined the relationship between morbidity and other factors. Our analysis indicated that the population density in cities in Hubei province where the COVID-19 was severe was associated with a higher percentage of morbidity, with an r value of 0.62. Similarly, in the USA, the density of 51 states and territories is also associated with morbidity from COVID-19 with an r value of 0.55. In contrast, as a control group, there is no association between the morbidity and population density in 33 other regions of China, where the COVID-19 epidemic is well under control. Interestingly, our study also indicated that these associations were not influenced by the first case of COVID-19. The rate of morbidity and the number of days from the first case in the USA have no association, with an r value of - 0.1288. Population density is positively associated with the percentage of patients with COVID-19 infection in the population. Our data support the importance of such as social distancing and travel restriction in the prevention of COVID-19 spread., (© 2021. This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.)
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- 2021
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3. Democracy and case fatality rate of COVID-19 at early stage of pandemic: a multicountry study.
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Yao L, Li M, Wan JY, Howard SC, Bailey JE, and Graff JC
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- Democracy, Humans, SARS-CoV-2, World Health Organization, COVID-19, Pandemics
- Abstract
Many studies have evaluated factors that influence the course of the COVID-19 pandemic in different countries. This multicountry study assessed the influence of democracy and other factors on the case fatality rate of COVID-19 during the early stage of the pandemic. We accessed the World Health Organization, World Bank, and the Democracy Index 2019 databases for data from the 148 countries. Multiple analyses were conducted to examine the association between the Democracy Index and case fatality rate of COVID-19. Within 148 countries, the percentage of the population aged 65 years and above (p = 0.0193), and health expenditure as a percentage of GDP (p = 0.0237) were positively associated with countries' case fatality rates. By contrast, hospital beds per capita helped to reduce the case fatality rates. In particular, the Democracy Index was positively associated with case fatality rates in a subgroup of 47 high-income countries. This study suggests that enhancing the health system with increased hospital beds and healthcare workforce per capita should reduce case fatality rate. The findings suggest that a higher Democracy Index is associated with more deaths from COVID-19 at the early stage of the pandemic, possibly due to the decreased ability of the government., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2022
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4. African American Women Breast Cancer Survivors: Coping with the COVID-19 Pandemic.
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Hamilton JB, Abiri AN, Nicolas CA, Gyan K, Chandler RD, Worthy VC, and Grant EJ
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- Female, Humans, Black or African American, Pandemics, Adaptation, Psychological, Breast Neoplasms, Cancer Survivors, COVID-19 epidemiology
- Abstract
African American women breast cancer survivors are among those with the greater burden of cancer. Breast cancer is the second leading cause of death among black women, and this death rate is 40% higher than that of white women. The COVID-19 pandemic increased the burden of morbidity and mortality among this population of cancer survivors. In this report, we explore the ways in which the COVID-19 pandemic was a source of stress for African American women breast cancer survivors and their subsequent responses to these stressors. This is a qualitative descriptive study with content analysis of data from the narratives of 18 African American breast cancer survivors. Participants were interviewed via phone and video conferencing platform and asked questions related to their experiences with the COVID-19 pandemic. The findings suggest stressors associated with (1) potential COVID-19 spreaders in their immediate environments; (2) closures and restricted access to social- and faith-based activities; (3) televised news broadcasts of COVID-19; and (4) disruptions to planned cancer prevention and control healthcare. Three categories emerged that captured the ways in which these women responded to stressors during the early phase of this pandemic: (1) seeking control in their social environments; (2) following the rules; and (3) seeking support from God, family, and friends. These findings can be used to better support breast cancer patients during the early phases of a pandemic., (© 2023. The Author(s) under exclusive licence to American Association for Cancer Education.)
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- 2023
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5. Effects of strict containment policies on COVID-19 pandemic crisis: lessons to cope with next pandemic impacts.
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Coccia M
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- Humans, Pandemics prevention & control, SARS-CoV-2, Health Policy, Public Policy, COVID-19
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The goal of the study here is to analyze and assess whether strict containment policies to cope with Coronavirus Disease 2019 (COVID-19) pandemic crisis are effective interventions to reduce high numbers of infections and deaths. A homogenous sample of 31 countries is categorized in two sets: countries with high or low strictness of public policy to cope with COVID-19 pandemic crisis. The findings here suggest that countries with a low intensity of strictness have average confirmed cases and fatality rates related to COVID-19 lower than countries with high strictness in containment policies (confirmed cases are 24.69% vs. 26.06% and fatality rates are 74.33% vs. 76.38%, respectively, in countries with low and high strictness of COVID-19 public policies of containment). What this study adds is that high levels of strict restriction policies may not be useful measures of control in containing the spread and negative impact of pandemics similar to COVID-19 and additionally a high strictness in containment policies generates substantial social and economic costs. These findings can be explained with manifold socioeconomic and environmental factors that support transmission dynamics and circulation of COVID-19 pandemic. Hence, high levels of strictness in public policy (and also a high share of administering new vaccines) seem to have low effectiveness to stop pandemics similar to COVID-19 driven by mutant viral agents. These results here suggest that the design of effective health policies for prevention and preparedness of future pandemics should be underpinned in a good governance of countries and adoption of new technology, rather than strict and generalized health polices having ambiguous effects of containment in society., (© 2022. The Author(s).)
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- 2023
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6. The ISO 26000's labor environmental issues during COVID-19: does corporate social responsibility help? Evidence from the Egyptian small and medium enterprises.
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Kholaif MMNHK, Ming X, Moosa A, and David KG
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- Egypt, Humans, Pandemics, SARS-CoV-2, Social Responsibility, COVID-19
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Based on both the "stakeholder" and "cognitive" theories, this study shed light on the optimistic side of the COVID-19 pandemic, as it also brings the concepts of corporate social responsibility (CSR) and sustainability back into the light, which helps in solving the labor environmental issues. Our research aims to profoundly investigate the correlation between CSR and labor environmental issues based on the International Organization for Standardization's standard 26,000 (ISO 26000) during COVID-19 and to also examine how CSR practices help solve labor environmental issues in the Egyptian small and medium enterprises (SMEs). Partial least squares structural equation modeling (PLS-SEM) was adopted, for data analysis and hypotheses testing, on a sample of 307 manager-level employees in the Egyptian SMEs. Results indicate that CSR positively impacts labor practices dimensions (employment relationships, human development and training, social dialog, and health and safety at work). However, CSR has an insignificant effect on social protection and work conditions. This study is scientifically valuable since it helps better understand the pandemic's effects on environmental labor issues in the Egyptian SMEs and shows how CSR helps solve those issues. Also, it discussed the theoretical contributions and practical implications and showed the limitations and future research for this study area., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2022
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7. Impact of the COVID-19 pandemic on interest in renal diseases.
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Oto OA, Kardeş S, Guller N, Safak S, Dirim AB, Başhan Y, Demir E, Artan AS, Yazıcı H, and Turkmen A
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- Humans, Infodemiology, Pandemics, SARS-CoV-2, Search Engine, COVID-19, Kidney Diseases epidemiology
- Abstract
There is an information gap about the public's interest in nephrological diseases in the COVID-19 era. The objective was to identify public interest in kidney diseases during the pandemic. In this infodemiology study, Google Trends was queried for a total of 50 search queries corresponding to a broad spectrum of nephrological diseases and the term "nephrologist." Two time intervals of 2020 (March 15-July 4 and July 5-October 31) were compared to similar time intervals of 2016-2019 for providing information on interest in different phases of the pandemic. Compared to the prior 4 years, analyses showed significant decreases in relative search volume (RSV) in the majority (76%) of search queries on March 15-July 4, 2020 period. However, RSV of the majority of search queries (≈70%) on July 5-October 31, 2020 period was not significantly different from similar periods of the previous 4 years, with an increase in search terms of amyloidosis, kidney biopsy, hematuria, chronic kidney disease, hypertension, nephrolithiasis, acute kidney injury, and Fabry disease. During the early pandemic, there have been significant decreases in search volumes for many nephrological diseases. However, this trend reversed in the period from July 5 to October 31, 2020, implying the increased need for information on kidney diseases. The results of this study enable us to understand how COVID-19 impacted the interest in kidney diseases and demands/needs for kidney diseases by the general public during the pandemic., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2022
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8. Nutrition and Brain Development.
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Cusick SE, Barks A, and Georgieff MK
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- Iron metabolism, Brain metabolism, Nutritional Status
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All nutrients are essential for brain development, but pre-clinical and clinical studies have revealed sensitive periods of brain development during which key nutrients are critical. An understanding of these nutrient-specific sensitive periods and the accompanying brain regions or processes that are developing can guide effective nutrition interventions as well as the choice of meaningful circuit-specific neurobehavioral tests to best determine outcome. For several nutrients including protein, iron, iodine, and choline, pre-clinical and clinical studies align to identify the same sensitive periods, while for other nutrients, such as long-chain polyunsaturated fatty acids, zinc, and vitamin D, pre-clinical models demonstrate benefit which is not consistently shown in clinical studies. This discordance of pre-clinical and clinical results is potentially due to key differences in the timing, dose, and/or duration of the nutritional intervention as well as the pre-existing nutritional status of the target population. In general, however, the optimal window of success for nutritional intervention to best support brain development is in late fetal and early postnatal life. Lack of essential nutrients during these times can lead to long-lasting dysfunction and significant loss of developmental potential., (© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.)
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- 2022
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9. Does temperature matter for COVID-19 transmissibility? Evidence across Pakistani provinces.
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Irfan M, Ikram M, Ahmad M, Wu H, and Hao Y
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- Humans, Pakistan, Pandemics, SARS-CoV-2, Temperature, COVID-19
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The outbreak of novel coronavirus (COVID-19) has become a global concern that is deteriorating environmental quality and damaging human health. Though some researchers have investigated the linkage between temperature and COVID-19 transmissibility across different geographical locations and over time, yet these studies are scarce. This study aims to bridge this gap using daily temperature and COVID-19 cases (transmissibility) by employing grey incidence analysis (GIA) models (i.e., Deng's grey incidence analysis (DGIA), the absolute degree GIA (ADGIA), the second synthetic degree GIA (SSDGIA), the conservative (maximin) model) and correlation analysis. Data on temperature are accessed from the NASA database, while the data on COVID-19 cases are collected from the official website of the government of Pakistan. Empirical results reveal the existence of linkages between temperature and COVID-19 in all Pakistani provinces. These linkages vary from a relatively stronger to a relatively weaker linkage. Based on calculated weights, the strength of linkages is ranked across provinces as follows: Gilgit Baltistan (0.715301) > Baluchistan (0.675091) > Khyber Pakhtunkhwa (0.619893) > Punjab (0.619286) > Sindh (0.601736). The disparity in the strength of linkage among provinces is explained by the discrepancy in the intensity of temperature. Besides, the diagrammatic correlation analysis shows that temperature is inversely linked to COVID-19 cases (per million persons) over time, implying that low temperatures are associated with high COVID-19 transmissibility and vice versa. This study is among the first of its kind to consider the linkages between temperature and COVID-19 transmissibility for a tropical climate country (Pakistan) using the advanced GIA models. Research findings provide an up-to-date glimpse of the outbreak and emphasize the need to raise public awareness about the devastating impacts of the COVID-19. The educational syllabus should provide information on the causes, signs, and precautions of the pandemic. Additionally, individuals should practice handwashing, social distancing, personal hygiene, mask-wearing, and the use of hand sanitizers to ensure a secure and supportive atmosphere for preventing and controlling the current pandemic., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2021
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10. Changing intergenerational patterns of emotional dysregulation in families with perinatal borderline personality disorder.
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Sved Williams A, Osborn A, Yelland C, and Hollamby S
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- Emotions, Female, Humans, Infant, Mothers, Parenting, Pilot Projects, Borderline Personality Disorder therapy
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A pilot study with women with borderline personality disorder (BPD) and their infants showed promising results. This clinical research program sought to discover whether ongoing implementation confirmed preliminary results in relation to maternal mental health and, in addition, whether parenting and the mother-infant relationship showed sufficient improvement. Women with BPD and their infants were referred to a 25-week group program of Mother-Infant Dialectical Behavior Therapy (MI-DBT). During groups, infants were provided care by childcare workers while mothers took part in a skills training session. Mothers and infants then reunited and took part in an activity together that incorporated skills taught in the teaching session. Sixty-nine of 98 women commencing MI-DBT completed the program, demonstrating a 71% completion rate. Women showed improvement on all measures of mental health including depression, anxiety, and BPD symptoms. While women reported improvement in parenting confidence, an objective measure of the mother-infant relationship showed continuation of concerning relationships in a significant percentage. MI-DBT was found to be effective at improving mothers' mental health, both at the initial site and in community settings, with different clinicians and with different childcare options. While there were some improvements found in measures of the mother's perception of the infant-parent relationship, there were no significant improvements in currently used observational measures of the interaction or the infant's social-emotional development, suggesting that additional intervention such as infant-parent therapy may be needed to augment the benefits of MI-DBT to improve outcomes in these areas.
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- 2021
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11. The Diagnostic Period for Autism: Risk and Protective Factors for Family Quality of Life in Early Childhood
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Rivard, Mélina, Morin, Diane, Coulombe, Patrick, Morin, Marjorie, and Mello, Catherine
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Pervasive developmental disorders -- Diagnosis -- Risk factors -- Care and treatment ,Family services -- Usage ,Quality of life -- Demographic aspects ,Health - Abstract
During the diagnostic evaluation period for autism or intellectual disability (ID), families of young children are at risk for poor adjustment. The present study aimed to document family quality of life (FQOL), along with associated risk and protective factors, during this critical step of families' services trajectory. FQOL was measured in a large sample of families of children recently diagnosed with a neurodevelopmental disorder and examined in relation to the type of services received, children's clinical profile, and family variables. FQOL was related to types of services, children's challenging behavior, parenting stress, and several aspects of family composition and status. These findings highlight a need for mental health support for parents, coaching interventions for challenging behaviors, and family-centered supports., Author(s): Mélina Rivard [sup.1] , Diane Morin [sup.1] , Patrick Coulombe [sup.2] , Marjorie Morin [sup.1] , Catherine Mello [sup.3] Author Affiliations: (1) grid.38678.32, 0000 0001 2181 0211, Université du [...]
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- 2023
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12. Family Functioning and Emotional Aspects of Children with Autism Spectrum Disorder in Southern Brazil
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Flenik, Tatiana M. N., Bara, Tiago S., and Cordeiro, Mara L.
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Pervasive developmental disorders -- Diagnosis -- Demographic aspects ,Autistic children -- Care and treatment ,Health - Abstract
Autism spectrum disorder (ASD) affects children and their families. We investigated the family environment of children with ASD in Brazil. Twenty-one families participated. Outcome measures administered to parents included the Strengths and Difficulties Questionnaire, Questionnaire on Resources and Stress-Short Form, and the Family Environment Scale. All families reported a number of difficulties, including social interactions and peer relationships, stress levels, and communication difficulties. Families also reported great concern for their child's future. Brazil is a developing country, yet there are few national resources and studies related to ASD. The challenges continue from diagnosis through treatment. Our results emphasize the need to understand the family environment of children with autism and their parents' apprehensions to develop effective coping programs., Author(s): Tatiana M. N. Flenik [sup.1] , Tiago S. Bara [sup.1] [sup.2] , Mara L. Cordeiro [sup.1] [sup.2] [sup.3] Author Affiliations: (1) Faculdades Pequeno Príncipe, , Curitiba, Brazil (2) grid.517863.e, [...]
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- 2023
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13. Acceptance and Commitment Therapy Group Intervention for Parents of Children with Disabilities (Navigator ACT): An Open Feasibility Trial
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Holmberg Bergman, T., Renhorn, E., Berg, B., Lappalainen, P., Ghaderi, A., and Hirvikoski, T.
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Mental health -- Care and treatment ,Disabled children -- Care and treatment ,Parenting -- Evaluation ,Health - Abstract
Parents of children with autism spectrum disorder and other disabilities report high levels of distress, but systematically evaluated interventions are few. This study aimed to evaluate the feasibility of a novel, manualized Acceptance and Commitment Therapy group intervention (Navigator ACT) in a sample of 94 parents of children with disabilities. Feasibility was measured by treatment completion, credibility, and satisfaction, and preliminary outcomes by using self-rating scales administered at the baseline, post-intervention, and follow-up. The results imply the intervention is feasible in the context of Swedish outpatient habilitation services. A preliminary analysis of the outcome measures suggests that parents experienced significant improvements in well-being. The results indicate that the treatment is feasible and should be evaluated in a randomized controlled trial., Author(s): T. Holmberg Bergman [sup.1] [sup.2] [sup.3] , E. Renhorn [sup.1] [sup.2] [sup.3] , B. Berg [sup.2] , P. Lappalainen [sup.5] , A. Ghaderi [sup.4] , T. Hirvikoski [sup.1] [sup.2] [...]
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- 2023
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14. Homicide Incidents Involving Children with Autism Spectrum Disorder as Victims Reported in the US News Media, 2000-2019
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Guan, Joseph, Blanchard, Ashley, DiGuiseppi, Carolyn G., Chihuri, Stanford, and Li, Guohua
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Homicide -- Media coverage -- Demographic aspects ,Autistic children -- Demographic aspects -- Crimes against ,Health - Abstract
Recent research indicates that children with autism are at increased risk of maltreatment. We examined news media reports on homicide incidents involving children with autism as victims in the United States between 2000 and 2019. Of the 52 victims studied, 47 (90.4%) were male. Age of victims ranged from 2 to 20 years (mean = 10.4 ± 5.3 years). Parents and other caregivers accounted for 63.5% and 13.5% of the perpetrators, respectively. The leading injury mechanism was gunshot wounds (23.1%), followed by drowning (19.2%), and suffocation, strangulation, or asphyxiation (19.2%). The most commonly cited contributing factor (47.1%) was overwhelming stress from caring for the autistic child. These results underscore the importance of supporting services for caregivers of children with autism., Author(s): Joseph Guan [sup.1] , Ashley Blanchard [sup.2] , Carolyn G. DiGuiseppi [sup.3] , Stanford Chihuri [sup.4] , Guohua Li [sup.4] [sup.5] Author Affiliations: (1) grid.262743.6, 0000000107058297, Rush Medical College, [...]
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- 2022
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15. Externalizing Behaviors are Associated with Increased Parenting Stress in Caregivers of Young Children with Autism
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Olson, Lindsay, Chen, Bosi, Ibarra, Cynthia, Wang, Tiffany, Mash, Lisa, Linke, Annika, and Kinnear, Mikaela
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Parents -- Psychological aspects -- Health aspects ,Pervasive developmental disorders -- Diagnosis -- Complications and side effects -- Demographic aspects ,Stress (Psychology) -- Demographic aspects -- Risk factors ,Health - Abstract
Parents of children diagnosed with autism spectrum disorder (ASD) report higher levels of stress than parents of typically developing children. Few studies have examined factors associated with parental stress in early childhood. Even fewer have investigated the simultaneous influence of sociodemographic, clinical, and developmental variables on parental stress. We examined factors associated with stress in parents of young children with ASD. Multiple regression models were used to test for associations between socioeconomic indices, developmental measures, and parental stress. Externalizing behaviors, communication, and socialization skills accounted for variance in parental stress, controlling for ASD diagnosis. Results highlight the importance of interventions aimed at reducing externalizing behaviors in young children as well as addressing stress in caregivers of children with ASD., Author(s): Lindsay Olson [sup.1] [sup.2] , Bosi Chen [sup.1] [sup.2] , Cynthia Ibarra [sup.1] , Tiffany Wang [sup.1] , Lisa Mash [sup.1] [sup.2] , Annika Linke [sup.1] , Mikaela Kinnear [...]
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- 2022
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16. Quality of Life Among Malaysian Parents with Autism Spectrum Disorder Child: The Double ABCX Model Approach
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Ismail, Mohd Fahmi, Safii, Razitasham, Saimon, Rosalia, and Rahman, Md. Mizanur
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Pervasive developmental disorders -- Health aspects -- Social aspects ,Parenting -- Social aspects -- Psychological aspects -- Health aspects ,Quality of life -- Health aspects ,Autistic children -- Social aspects ,Health - Abstract
This paper reported the quality of life (QoL) of 260 Malaysian parents with autism spectrum disorder (ASD) and factors which influencing it. About half of these parents reported to having good QoL. The factors identified in the double ABCX model showed that perceived social support and sense of coherence (SOC) were mediated by coping strategies and had a positive direct and indirect effect on parents' QoL. These finding reiterate the importance of social support, coping skills, and strong SOC reflection skills in influencing the QoL of parents with ASD child. We therefore suggest parents to utilize the widely available social and organization supports to gain good QoL, which is also important for the wellbeing of their child., Author(s): Mohd Fahmi Ismail [sup.1] , Razitasham Safii [sup.1] , Rosalia Saimon [sup.1] , Md. Mizanur Rahman [sup.1] Author Affiliations: (1) grid.412253.3, 0000 0000 9534 9846, Department of Community Medicine [...]
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- 2022
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17. Fungal Resources for Sustainable Economy : Current Status and Future Perspectives
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Ishwar Singh, Vijay Rani Rajpal, Shrishail S. Navi, Ishwar Singh, Vijay Rani Rajpal, and Shrishail S. Navi
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- Fungi in agriculture, Sustainable development, Fungi, Mycology
- Abstract
This edited book provides a comprehensive account of the new developments in various facets of fungal biology related to the impact and application of fungi on the sustainable economy. The book consists of 24 chapters distributed under five sections written by active researchers and academicians from India and abroad. The five sections of the book are- 1. Fungi in Sustainable Economy, 2. Fungal Resources: Current and Potential Industrial Applications, 3. Fungal Resources: Current and Potential Agricultural Applications, 4. Fungi and their Secondary metabolites: Implications and 5. Fungi: Burden to health and Indoor Environment.The book explores the utility of fungi as food, enzymes, organic compounds, nutraceuticals, pharmaceuticals and agricultural productivity promoter. It also highlights the negative fungal impacts on food production, health and environment. The book is useful to postgraduate students studying mycology, plant pathology, crop protection, agricultural sciences, and plant sciences. In addition, scientists involved in biological and agricultural research, crop management, and various industries that manufacture or utilize fungal products on a small to large scale shall also find the book helpful.
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- 2023
18. Sleep Medicine : A Comprehensive Guide for Transitioning Pediatric to Adult Care
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Amir Sharafkhaneh, David Gozal, Amir Sharafkhaneh, and David Gozal
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- Adulthood, Sleep disorders in adolescence--Treatment, Sleep disorders--Treatment
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Many fields of medicine have looked at the issue of transitioning care from pediatrics to adults. This book focuses on that transition within the field of sleep medicine. This book gathers and presents in volume information that will assist practitioners to transition the care of their pediatric patients suffering from sleep disorders. The book will discuss anatomical, physiological and psychological aspects as children grow into adulthood. Specifically, changes in brain function and anatomy, cardiorespiratory function and anatomy, and changes in facial structure are explored. Also discussed are the tools that are used for assessing sleep and how it may apply differently to children and adults. Chapters cover each group of sleep disorders with focus on how the diagnosis, prognosis, and management may change with the transition from childhood through adolescence to adulthood. In addition, gaps in needs and research are discussed.
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- 2023
19. Neurodevelopmental Pediatrics : Genetic and Environmental Influences
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David D. Eisenstat, Dan Goldowitz, Tim F. Oberlander, Jerome Y. Yager, David D. Eisenstat, Dan Goldowitz, Tim F. Oberlander, and Jerome Y. Yager
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- Pediatric neuropsychology, Pediatric neurology, Developmental disabilities--Genetic aspects
- Abstract
This book explores the interrelationship of genetics, the environment, or both, in the causation of three neurodevelopmental disorders: autism/autism spectrum disorder (ASD), fetal alcohol spectrum disorder (FASD), and cerebral palsy (CP). It links common clinical problems in developmental pediatrics and pediatric neurology to current concepts and translational research advances in developmental neurosciences, medical genetics, and related disciplines. The first section of the book provides a comprehensive and up-to-date overview of development of the brain, including topics such as neuronal stem cells, epigenetics, and the influence of the prenatal environment. The next three sections analyze the epidemiology, diagnosis, interventions, and controversies and research directions associated with each of the three neurodevelopmental disorders. It also examines co-morbidities common to all three disorders, such as disturbed sleep, seizures, behavioral disorders, and pain. It concludes by highlighting the impact of ASD, FASD, and CP on family dynamics and provides tools and resources based on foundational concepts such as neuroethics, bioinformatics, community engagement, and advocacy. Learning objectives, key points, clinical vignettes, and multiple choice questions are incorporated throughout the book. With its comprehensive treatment of disease mechanisms, genetics, and pathophysiology associated with these disorders and its discussion of potential therapies and novel treatments, Neurodevelopmental Pediatrics: Genetic and Environmental Influences is an essential resource for developmental pediatricians, child neurologists, fellows, residents and graduate students.
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- 2023
20. Proceedings of ASEAN-Australian Engineering Congress (AAEC2022) : Engineering Solutions in the Age of Digital Disruption
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Chung Siung Choo, Basil T. Wong, Khairul Hafiz Bin Sharkawi, Daniel Kong, Chung Siung Choo, Basil T. Wong, Khairul Hafiz Bin Sharkawi, and Daniel Kong
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- Control engineering, Robotics, Automation, Internet of things, Industrial engineering, Production engineering
- Abstract
This book presents the proceedings of the ASEAN-Australian Engineering Congress (AAEC2022), held as a virtual event, 13–15 July 2022 with the theme “Engineering Solutions in the Age of Digital Disruption”. The book presents selected papers covering scientific research in the field of Engineering Computing, Network, Communication and Cybersecurity, Artificial Intelligence & Machine Learning, Materials Science & Manufacturing, Automation and Sensors, Smart Energy & Cities, Simulation & Optimisation and other Industry 4.0 related Technologies. The book appeals to researchers, academics, scientists, students, engineers and practitioners who are interested in the latest developments and applications related to addressing the Fourth Industrial Revolution (IR4.0).
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- 2023
21. Advancements in Materials Science and Technology Led by Women
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Azman Ismail, Fatin Nur Zulkipli, Husna Sarirah Husin, Andreas Öchsner, Azman Ismail, Fatin Nur Zulkipli, Husna Sarirah Husin, and Andreas Öchsner
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- Women in science, Materials science
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This book is a noteworthy series of works authored by women from diverse research areas and expertise. This book contains research papers from fundamental, experimental, and empirical studies in the fields of mechanical engineering and materials science is included in this book series. Methods for modelling data, structures, and materials using numerical and analytical techniques are described along with experimental data and methodologies.
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- 2023
22. Parenting Stress and its Associated Components Prior to an Autism Spectrum Disorder (ASD) Diagnostic Evaluation
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Voliovitch, Yair, Leventhal, John M., Fenick, Ada M., Gupta, Abha R., Feinberg, Emily, Hickey, Emily J., and Shabanova, Veronika
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Pervasive developmental disorders -- Diagnosis -- Risk factors ,Parenting -- Psychological aspects -- Health aspects ,Stress (Psychology) -- Demographic aspects -- Health aspects ,Health - Abstract
Parents of children with autism spectrum disorder (ASD) show increased levels of parenting stress, but only one study has examined this association before a diagnostic evaluation. We conducted a cross-sectional study of parenting stress in 317 low SES parents with children at-risk for ASD before a diagnostic evaluation. Multiple regression modeling evaluated the associations between parenting stress and parent and child factors. Parenting stress was negatively associated with social support and positively associated with active avoidance coping and parental worry. However, parenting stress was not associated with the child's ASD symptom severity or adaptive functioning, except for self-direction. Findings suggest parenting stress among parents of children at risk of ASD should be assessed prior to diagnosis., Author(s): Yair Voliovitch [sup.1] [sup.5] , John M. Leventhal [sup.1] , Ada M. Fenick [sup.1] , Abha R. Gupta [sup.1] , Emily Feinberg [sup.2] [sup.3] , Emily J. Hickey [sup.2] [...]
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- 2021
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23. Nutrition and Psychiatric Disorders
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Wael Mohamed, Firas Kobeissy, Wael Mohamed, and Firas Kobeissy
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- Nutrition--Psychological aspects, Mental health--Nutritional aspects
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The book comprehensively reviews the role of nutrition in psychiatric disorders. It provides mechanistic insights into the effects of nutrition on metabolic pathways, mitochondrial nutrients, neurodegeneration and CNS disorders, cell signaling, and neuronal functions. The book further highlights the role of diet in preventing and treating mental health and modifying drug treatment effects. Further, it explores the relationship between nutrition and psychiatric disorders, including depression, autism, anxiety, Attention-Deficit / Hyperactivity Disorder, and OCD. The book further explores the recent advancements in understanding the important role of nutrients as therapeutics in various psychiatric disorders. Lastly, it presents an overview of nutrients as neuroprotective agents along with the main principles of nutrigenomics. The book is essential reading for neuroscientists interested interest in food therapeutic strategies.
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- 2022
24. Sensitive Periods of Brain Development and Preventive Interventions
- Author
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Susan L. Andersen and Susan L. Andersen
- Subjects
- Brain--Growth, Nature and nurture, Child development
- Abstract
Sensitive periods occur when unique experiences permanently influence brain development either by their presence or absence. This volume covers underlying brain systems and behaviors that are sculpted by the environment in humans and animals in a search for commonalities. The mechanisms involved, the importance of timing in the process, and factors that can change the brain are discussed in this exciting book. Different chapters examine how experience guides the development of cells, circuits, and function using vision, cortical circuits, and cognition as frameworks. Scientific evidence for effective preventative intervention approaches, including diet, exercise, and music, are included to find ways to maximize child and adolescent development. The adverse effects of early brain injury are also included. As sensitive periods are gaining importance in their application in the real-world, novel statistical approaches for human studies are presented and the importance of sensitive periodsare covered by examining the juvenile justice system. The book has interdisciplinary appeal and scholars with an interest in brain resiliency or vulnerability will find it of particular interest.
- Published
- 2022
25. COVID 19, Containment, Life, Work and Restart : Urban Studies
- Author
-
T. M. Vinod Kumar and T. M. Vinod Kumar
- Subjects
- Sustainability, Medicine, Preventive, Health promotion, Internet of things, Sociology, Urban
- Abstract
This book is about containment, life, work, and restart cities affected by COVID 19, using selected empirical case studies. This book presents the spread of coronavirus spatially and temporally, analyses containment strategies and includes recommended strategies. Further, it analyses how life and work get transformed during the lockdown, and gradual opening up, and presents the future of work and life in cities impacted by COVID-19. This book discusses the concept of smart life and works in cities post-COVID-19 such that they do not reduce the quality of work and life and cannot create adverse economic and living consequences called the restart of a city after COVID-19.Selected Cities of special interest are studied. Special interest is because Kerala and Maharashtra got the worst affected in India by COVID 19 pandemic and the book focus on that.
- Published
- 2022
26. Perceptions of Families of Individuals with Autism Spectrum Disorder during the COVID-19 Crisis
- Author
-
Manning, Janessa, Billian, Joseph, Matson, Jill, Allen, Colleen, and Soares, Neelkamal
- Subjects
Pervasive developmental disorders -- Diagnosis -- Social aspects ,Domestic relations -- Psychological aspects ,Health - Abstract
Caring for an individual with autism spectrum disorder (ASD) in ideal circumstances can be stressful, and the Coronavirus disease (COVID-19) pandemic created a high degree of disruption to life and stress to families living with an individual with ASD. We conducted an online survey of families in Michigan that revealed higher levels of stress in caregivers of younger individuals with ASD and those with greater severity of ASD symptoms. Stress around therapeutic service disruption, finances, and illness predominated and greater stress was reported for caregivers of individuals receiving greater intensity of services pre-COVID-19. Respondents voiced concerns about receiving respite care during COVID-19, and those expressing interest in respite also reported greater symptom severity in the person with ASD., Author(s): Janessa Manning [sup.1] , Joseph Billian [sup.2] , Jill Matson [sup.1] , Colleen Allen [sup.1] , Neelkamal Soares [sup.3] Author Affiliations: (1) Autism Alliance of Michigan, , 48025, Bingham [...]
- Published
- 2021
- Full Text
- View/download PDF
27. Emerging Trends in Plant Pathology
- Author
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Krishna P. Singh, Shamarao Jahagirdar, Birinchi Kumar Sarma, Krishna P. Singh, Shamarao Jahagirdar, and Birinchi Kumar Sarma
- Subjects
- Plant genetics, Plant diseases, Botanical chemistry, Plant physiology
- Abstract
This book offers a comprehensive guide to the identification, detection, characterization, classification and management of plant pathogens and other beneficial microbes in agriculture. The science of plant pathology is a dynamic field and, given the growing interest in sustainable agricultural practices, plant disease management has also gained importance. Further, there has been a shift from traditional chemical-based methods to eco-friendly integrated disease management strategies with a greater focus on bio-control and other eco-friendly technologies. This book provides a comprehensive and timely account of latest concepts and advances in the field of plant pathology, including detection and diagnosis, host resistance, disease forecasting and plant biotechnological approaches. Accordingly, it will be of great interest to academics and all stakeholders working in the fields of plant pathology, microbiology, biotechnology, plant breeding, and other life sciences.
- Published
- 2021
28. Applications of Artificial Intelligence in COVID-19
- Author
-
Sachi Nandan Mohanty, Shailendra K. Saxena, Suneeta Satpathy, Jyotir Moy Chatterjee, Sachi Nandan Mohanty, Shailendra K. Saxena, Suneeta Satpathy, and Jyotir Moy Chatterjee
- Subjects
- Artificial intelligence, COVID-19 (Disease)--Data processing, Artificial intelligence--Medical applications
- Abstract
The book examines the role of artificial intelligence during the COVID-19 pandemic, including its application in i) early warnings and alerts, ii) tracking and prediction, iii) data dashboards, iv) diagnosis and prognosis, v) treatments, and cures, and vi) social control. It explores the use of artificial intelligence in the context of population screening and assessing infection risks, and presents mathematical models for epidemic prediction of COVID-19. Furthermore, the book discusses artificial intelligence-mediated diagnosis, and how machine learning can help in the development of drugs to treat the disease. Lastly, it analyzes various artificial intelligence-based models to improve the critical care of COVID-19 patients.
- Published
- 2021
29. COVID-19 Pandemic Dynamics : Mathematical Simulations
- Author
-
Igor Nesteruk and Igor Nesteruk
- Subjects
- COVID-19 Pandemic, 2020---Forecasting, COVID-19 Pandemic, 2020---Mathematical models
- Abstract
This book highlights the estimate of epidemic characteristics for different countries/regions in the world with the use of known SIR (susceptible-infected-removed) model for the dynamics of the epidemic, the known exact solution of the linear differential equations and statistical approach developed before. The COVID-19 pandemic is of great interest to researchers due to its high mortality and a negative impact to the world economy. Correct simulation of the pandemic dynamics needs complicated mathematical models and many efforts for unknown parameters identification. The simple method of detection of the new pandemic wave is proposed and SIR model generalized. The hidden periods, epidemic durations, final numbers of cases, the effective reproduction numbers and probabilities of meeting an infected person are presented for countries like USA, Germany, UK, the Republic of Korea, Italy, Spain, France, the Republic of Moldova, Ukraine, and for the world. The presented information is useful to regulate the quarantine activities and to predict the medical and economic consequences of different/future pandemics.
- Published
- 2021
30. Endophytes : Potential Source of Compounds of Commercial and Therapeutic Applications
- Author
-
Ravindra H. Patil, Vijay L. Maheshwari, Ravindra H. Patil, and Vijay L. Maheshwari
- Subjects
- Microbial ecology, Pharmacology, Microbiology, Biotechnology
- Abstract
This book describes the various therapeutic and commercial applications of compounds produced by endophytes. Endophytes are microorganisms that reside in the living internal tissues of plants without showing any apparent symptom of their presence. During their life cycle, they establish a symbiotic or parasitic relationship with the host plant. The book discusses different kinds of compounds that these endophytes produce, and their potential properties such as antimicrobial, anti-oxidative, anti-inflammatory, anticancer, neutraceutical, immunomodulatory etc. Other prospects of entophytic biology such as fungi of wild and domesticated crop plants and their applications in sustainable agriculture have also been included. The book also provides details about various techniques used in endophyte research, metabolite detection and bioactivity-based assays to explore endophytes. Endophytes with phytohormones‐producing potential and their role in plant —microbial interactions under stress are also discussed. The book also highlights novel strategies to tap into the hidden potential of endophytic fungi for the production of novel biomolecules using an integrated approach.These microorganisms have attracted a lot of scientific attention worldwide because of their huge potential for novel phytochemicals, pharmaceuticals and lead compounds. Hundreds of new novel endophytic fungi have been isolated, identified and systematically studied in last decade. However, this is the first of its kind, systematic compilation of potential biotechnological applications of endophytic compounds. Chapter contributions from groups across the globe make this book very up-to-date and informative. This book is very useful and interesting for students and researchers in the field of microbiology, plant sciences, mycology and pharmacology. It is also helpful for industry experts working on developing novel compounds.
- Published
- 2021
31. Neotropical Endophytic Fungi : Diversity, Ecology, and Biotechnological Applications
- Author
-
Luiz Henrique Rosa and Luiz Henrique Rosa
- Subjects
- Plant-fungus relationships--Central America, Endophytic fungi--South America, Endophytic fungi--Central America, Plant-fungus relationships--South America, Fungi--Biotechnology--South America, Fungi--Biotechnology--Central America
- Abstract
This pioneering book focuses on Neotropical endophytic fungi, providing a comprehensive overview of their diversity, ecology, and biotechnological applications in medicine, agriculture, and industry. Despite their rich diversity, the endophytic fungi associated with plants of Central and South American biomes remain largely unknown. The book addresses that knowledge gap by offering insights into Neotropic endophytic fungal community.
- Published
- 2021
32. Essentials of Neurosurgical Anesthesia & Critical Care : Strategies for Prevention, Early Detection, and Successful Management of Perioperative Complications
- Author
-
Ansgar M. Brambrink, Jeffrey R. Kirsch, Ansgar M. Brambrink, and Jeffrey R. Kirsch
- Subjects
- Anesthesia--Complications, Anesthesia, Nervous system--Surgery--Complications, Nervous system--Surgery
- Abstract
This comprehensive, evidence-based book is intended to serve as a reference for medical practitioners involved in the perioperative care of neurosurgical patients. Fundamental aspects of neuroanesthesiology and neurocritical care are thoroughly examined across 101 chapters, outlining key elements that are crucial to a care provider's knowledge of the practice. These elements include specific diagnostic procedures and treatment options, concepts and applicable details of the available neurosurgical interventions and techniques, and mechanisms necessary to provide top of the line care for patients. Each chapter features definitive and distinct areas of this multi-specialty discipline, and is designed to guide the reader from problem to solution in situations that can arise in the clinical setting.Essentials of Neurosurgical Anesthesia & Critical Care, 2nd edition is a problem-oriented approach textbook that will aid a wide variety of readers in handling day-to-day issues and developments relevant to the perioperative care of neurosurgical patients.
- Published
- 2020
33. A Guide to Pediatric Anesthesia
- Author
-
Craig Sims, Dana Weber, Chris Johnson, Craig Sims, Dana Weber, and Chris Johnson
- Subjects
- Children, Human beings, Pediatric anesthesia, Anesthesia, Infants
- Abstract
The second edition of the successful book'Your Guide to Pediatric Anesthesia'offers a practical approach to pediatric anesthesia with a concise account of the topic in a reader-friendly format. The book begins with an overview of pediatric anesthesia then continues with chapters related to different pediatric surgeries and the relevant anesthetic issues, including a chapter of emergency scenarios in pediatric anesthesia. The final section has chapters containing past exam questions in pediatric anesthesia, a set of clinical scenarios written in an exam question and answer format, and a glossary of syndromes and conditions with brief, important information and practical recommendations. The book also includes an accurate and comprehensive index which helps readers guide themselves through the book. Written in a consistent, exam-focused, non-academic writing style, chapters provide a clear explanation of each topic with a review of management options, discussingadvantages and disadvantages, and concluding with a suggested practical approach in each case. It contains the syllabus for the College exams, but is also full of practical techniques and discussion for trainees during their pediatric rotation. It is relevant and useful for anesthetists who have completed their exams and are now caring for children in their practice. A Guide to Pediatric Anesthesia covers the important topics at a level suitable for trainees, occasional pediatric anesthetists and anesthetic assistants.
- Published
- 2020
34. Linking Child Autism to Parental Depression and Anxiety: The Mediating Roles of Enacted and Felt Stigma
- Author
-
Chan, Kevin Ka Shing and Leung, Donald Chi Kin
- Subjects
Pervasive developmental disorders -- Diagnosis -- Social aspects ,Parents -- Health aspects -- Psychological aspects ,Depression, Mental -- Risk factors -- Demographic aspects ,Anxiety -- Risk factors -- Demographic aspects ,Stigma (Social psychology) -- Influence ,Health - Abstract
This study examined whether child autistic symptoms would heighten parental affective symptoms through evoking enacted stigma from the community (i.e., public and courtesy stigma) and felt stigma within the parents (i.e., vicarious and self-stigma). Cross-sectional questionnaire data were collected from 441 parents of children with autism spectrum disorder. Path analyses showed that social communication and interaction deficits and restricted and repetitive behaviors in child autism were positively associated with public and courtesy stigma. While public stigma was positively associated with parental vicarious stigma, courtesy stigma was positively associated with parental self-stigma. Both vicarious and self-stigma were positively associated with depressive and anxiety symptoms among parents. Findings revealed how child autism could compromise parental well-being through exacerbating the family's stigmatizing experiences., Author(s): Kevin Ka Shing Chan [sup.1] [sup.2] , Donald Chi Kin Leung [sup.1] Author Affiliations: (1) grid.419993.f, 0000 0004 1799 6254, Department of Psychology, The Education University of Hong Kong, [...]
- Published
- 2021
- Full Text
- View/download PDF
35. Characterization of Family-Directed Care Coordination and Involvement in Behavioral Treatments in an Autism-Specific Medicaid Waiver
- Author
-
Chasson, Gregory S., Eskow, Karen Goldrich, Summers, Jean Ann, and Dreher, Taylor M.
- Subjects
Child health services -- Laws, regulations and rules -- Usage ,Community health services for children -- Laws, regulations and rules -- Usage ,Medicaid -- Laws, regulations and rules ,Behavior therapy -- Methods ,Parent and child -- Health aspects ,Community health services -- Laws, regulations and rules -- Usage ,Pediatric research ,Autistic children -- Care and treatment ,Government regulation ,Health - Abstract
Services for children with autism spectrum disorder (ASD) and their families have evolved with the advent of the Medicaid waiver, leading to more family-based coordination of care. Evaluating family involvement, the current investigation compared 230 families of children with ASD receiving Medicaid waiver services to a propensity-score matched group of 230 families who were waiting for such services (i.e., registry families). Compared to the registry, waiver families reported more involvement in service planning tasks, but not activities related to future-planning, managing crisis situations, or searching for and securing funding. Additional analyses characterize waiver families as engaging in high levels of coordinating and delivering behavioral interventions for their child. Implications for family burden and future programming for waiver programs are discussed., Author(s): Gregory S. Chasson [sup.1] , Karen Goldrich Eskow [sup.2] , Jean Ann Summers [sup.3] , Taylor M. Dreher [sup.1] Author Affiliations: (1) grid.62813.3e, 0000 0004 1936 7806, Department of [...]
- Published
- 2021
- Full Text
- View/download PDF
36. Nutrition and Immunity
- Author
-
Maryam Mahmoudi, Nima Rezaei, Maryam Mahmoudi, and Nima Rezaei
- Subjects
- Immunity--Nutritional aspects
- Abstract
This volume provides readers with a systematic assessment of current literature on the link between nutrition and immunity. Chapters cover immunonutrition topics such as child development, cancer, aging, allergic asthma, food intolerance, obesity, and chronic critical illness. It also presents a thorough review of microflora of the gut and the essential role it plays in regulating the balance between immune tolerance and inflammation. Written by experts in the field, Nutrition and Immunity helps readers to further understand the importance of healthy dietary patterns in relation to providing immunity against disorders and offering readily available immunonutritional programming in clinical care. It will be a valuable resource for dietitians, immunologists, endocrinologists and other healthcare professionals.
- Published
- 2019
37. Dental Care for Children with Special Needs : A Clinical Guide
- Author
-
Travis M. Nelson, Jessica R. Webb, Travis M. Nelson, and Jessica R. Webb
- Subjects
- Human beings, Infants, Children with disabilities--Dental care, Children
- Abstract
This concise manual offers best practice guidance on dental treatment of pediatric patients with special health care needs (CSHCN). The straightforward approaches described will enable clinicians to deliver high-quality, patient-centered care to children with intellectual and developmental disabilities. Readers will find up-to-date information on case-based treatment planning, alternative caries management strategies, the use of behavioral and pharmacological interventions to facilitate delivery of quality treatment, and a team approach to care. Practical clinical tips are provided on how to achieve and maintain oral health, including good oral hygiene and nutrition. A systematic framework for patient assessment and interaction with medical colleagues will assist readers in understanding when dental protocols must be altered. Other important topics include techniques for effective communication with CSHCN, behavioral strategies to improve treatment acceptance, the role of occupational therapy techniques, the sensory adapted dental environment, and the use protective stabilization.
- Published
- 2019
38. Medically Important Plant Biomes: Source of Secondary Metabolites
- Author
-
Dilfuza Egamberdieva, Antonio Tiezzi, Dilfuza Egamberdieva, and Antonio Tiezzi
- Subjects
- Agriculture, Sustainability, Biotic communities, Biodiversity, Plant ecology
- Abstract
This book provides insights into various aspects of medicinal plant-associated microbes, known to be a unique source of biological active compounds, including their biotechnological uses and their potential in pharmaceutical, agricultural and industrial applications. Featuring review papers and original research by leading experts in the field, it discusses medicinal plants and their interactions with the environment; medicinal plants as a source of biologically active compounds; medicinal plant-associated microbes (diversity and metabolites); their pharmaceutical, agricultural and industrial applications as well as their potential applications as plant growth stimulators and biocontrol agents. As such the book offers a valuable, up-to-date overview of the current research on medicinal plants, their ecology, biochemistry and associated biomes.
- Published
- 2019
39. SOLACE: A Psychosocial Stigma Protection Intervention to Improve the Mental Health of Parents of Autistic Children-A Feasibility Randomised Controlled Trial
- Author
-
Lodder, Annemarie, Papadopoulos, Chris, and Randhawa, Gurch
- Subjects
Parents -- Psychological aspects -- Health aspects -- Social aspects ,Parent and child -- Health aspects -- Psychological aspects -- Social aspects ,Stigma (Social psychology) -- Demographic aspects -- Health aspects ,Health - Abstract
This study presents findings from a feasibility trial, testing an 8-week psychosocial stigma protection intervention (SOLACE) designed to improve the mental health of parents of autistic children. Seventeen parents were stratified then randomly assigned to either SOLACE (n = 9) or control group (n = 8). Retention and adherence rates were excellent with minimal missing data suggesting SOLACE had good acceptability and feasibility. Quantitative analysis revealed that mental health scores had significantly improved for those who took part in SOLACE compared to no significant changes for control group participants. In addition, changes in secondary outcome measures (e.g. stigma, self-esteem and self-compassion) were in favour of SOLACE. Focus group interviews revealed that SOLACE was acceptable to parents. Results suggest that a full randomised controlled trial is warranted., Author(s): Annemarie Lodder [sup.1] , Chris Papadopoulos [sup.1] , Gurch Randhawa [sup.1] Author Affiliations: (1) grid.15034.33, 0000 0000 9882 7057, Institute for Health Research, University of Bedfordshire, , Putteridge Bury, [...]
- Published
- 2020
- Full Text
- View/download PDF
40. Brief Report: Stress and Perceived Social Support in Parents of Children with ASD
- Author
-
Drogomyretska, Kateryna, Fox, Robert, and Colbert, Dylan
- Subjects
Parents -- Surveys -- Psychological aspects -- Health aspects ,Caregivers -- Surveys -- Psychological aspects -- Health aspects ,Social networks -- Surveys -- Health aspects -- Psychological aspects ,Autistic children -- Care and treatment -- Social aspects ,Stress (Psychology) -- Surveys ,Health - Abstract
Previous literature has indicated that perceptions of social support (PSS) may be an important predictor of parental stress levels, particularly for parents of children diagnosed with autism spectrum disorders (ASD). The current study implemented structural equation modelling to further investigate the relationship between PSS and parental stress in a sample of 454 parents of children diagnosed with ASD. Results indicate that PSS derived from friends was the most important factor in protecting against stress, with PSS from both a significant other and family appearing to be less pervasive in this regard. In addition, the importance of PSS was further underlined by the finding that it remained a significant predictor of parental stress after controlling for the absence/presence of professional support., Author(s): Kateryna Drogomyretska [sup.1] , Robert Fox [sup.2] , Dylan Colbert [sup.1] Author Affiliations: (1) grid.462116.6, 0000 0000 9626 1897, Department of Psychology, Dublin Business School, , 73/83 South Georges [...]
- Published
- 2020
- Full Text
- View/download PDF
41. A Virtual Resiliency Intervention for Parents of Children with Autism: A Randomized Pilot Trial
- Author
-
Kuhlthau, Karen A., Luberto, Christina M., Traeger, Lara, Millstein, Rachel A., Perez, Giselle K., Lindly, Olivia J., and Chad-Friedman, Emma
- Subjects
Parents -- Health aspects -- Psychological aspects -- Training ,Mind and body therapies -- Testing -- Health aspects -- Psychological aspects ,Resilience (Personality trait) -- Training -- Health aspects -- Psychological aspects ,Autistic children -- Family -- Health aspects -- Training -- Psychological aspects ,Stress (Psychology) -- Risk factors -- Demographic aspects ,Health - Abstract
Parents of children with Autism experience high levels of stress. Resiliency is the ability to cope and adapt when faced with stressful events. This randomized, waitlist controlled pilot trial examines the feasibility, acceptability, and preliminary efficacy of an adapted virtual mind-body group intervention for parents of children with ASD. The intervention was feasible and acceptable. The immediate treatment group showed no difference in distress and greater improvement in resiliency and stress reactivity/coping relative to the delayed treatment group, (M difference 5.78; p = .038 and M difference 7.78; p = .001 respectively). Findings showed promising feasibility, acceptability, and preliminary efficacy for parents of children with ASD., Author(s): Karen A. Kuhlthau [sup.2] [sup.3] , Christina M. Luberto [sup.4] , Lara Traeger [sup.4] , Rachel A. Millstein [sup.1] [sup.4] , Giselle K. Perez [sup.1] [sup.4] , Olivia J. [...]
- Published
- 2020
- Full Text
- View/download PDF
42. Stigma and Forgiveness in Ghanaian Mothers of Children with Autism Spectrum Disorders (ASD)
- Author
-
Oti-Boadi, M., Dankyi, E., and Kwakye-Nuako, C. O.
- Subjects
Forgiveness -- Analysis -- Psychological aspects ,Mothers -- Family -- Psychological aspects -- Beliefs, opinions and attitudes -- Analysis ,Stigma (Social psychology) -- Analysis -- Psychological aspects ,Autistic children -- Family -- Beliefs, opinions and attitudes ,Health - Abstract
This study explored stigma experiences of mothers of children with ASD and forgiveness as their coping response. Semi-structured interviews were conducted with 6 mothers of children with ASD. Results of this study found several noteworthy themes including, feelings of mother, family/societal reactions, forgiveness factors, and impact of forgiveness. Mothers reported significant stigmatization from families and society. Some expressed their feelings towards themselves, others and God, and finally recounted the use of forgiveness as a coping resource which contributed significantly to their well-being. Findings from this study contribute to the emerging literature on forgiveness as a coping resource for persons who are offended. Implications for clinical practice, intervention and policy are discussed., Author(s): M. Oti-Boadi [sup.1] , E. Dankyi [sup.2] , C. O. Kwakye-Nuako [sup.3] Author Affiliations: (1) grid.8652.9, 0000 0004 1937 1485, Department of Psychology, University of Ghana, , Legon, LG [...]
- Published
- 2020
- Full Text
- View/download PDF
43. JIMD Reports, Volume 41 : Focus Issue: Adults and Metabolism
- Author
-
Eva Morava, Matthias Baumgartner, Marc Patterson, Shamima Rahman, Johannes Zschocke, Verena Peters, Eva Morava, Matthias Baumgartner, Marc Patterson, Shamima Rahman, Johannes Zschocke, and Verena Peters
- Subjects
- Metabolism, Inborn errors of, Metabolism--Disorders
- Abstract
JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
- Published
- 2018
44. Fungi and Their Role in Sustainable Development: Current Perspectives
- Author
-
Praveen Gehlot, Joginder Singh, Praveen Gehlot, and Joginder Singh
- Subjects
- Sustainable agriculture, Fungi--Economic aspects, Fungi--Industrial applications, Fungi--Biotechnology
- Abstract
This book illustrates the multiple roles of fungi in everyday life. Fungi are the large group of organisms with tremendous diversity and economic importance. Their ability to produce commercially efficient useful products makes them the vulnerable sustainable tool for the future generation. This book describes a systems approach and provides a means to share the latest developments and advances about the benefits of fungi including their wide application, traditional uses, modern practices, along with designing of strategies to harness their potential. The chapters are organized with data, providing information related to different sustainable aspects of fungi in agriculture, its cultivation and conservation strategies, industrial and environmental utilization, advanced bioconversion technologies and modern biotechnological interventions. Updated information and current opinion related to its application for sustainable agriculture, environment, and industries as futuristic tools havebeen presented and discussed in different chapters. The book also elucidates a comprehensive yet a representative description of the challenges associated with the sustained application of fungi to achieve the goals of sustainability.
- Published
- 2018
45. Medicinal Plants and Fungi: Recent Advances in Research and Development
- Author
-
Dinesh Chandra Agrawal, Hsin-Sheng Tsay, Lie-Fen Shyur, Yang-Chang Wu, Sheng-Yang Wang, Dinesh Chandra Agrawal, Hsin-Sheng Tsay, Lie-Fen Shyur, Yang-Chang Wu, and Sheng-Yang Wang
- Subjects
- Fungi--Therapeutic use, Medicinal plants
- Abstract
This book highlights the latest international research on different aspects of medicinal plants and fungi. Studies over the last decade have demonstrated that bioactive compounds isolated from medicinal fungi have promising antitumor, cardiovascular, immunomodulatory, anti-allergic, anti-diabetic, and hepatoprotective properties. In the light of these studies, the book includes chapters (mostly review articles) by eminent researchers from twelve countries across the globe working in different disciplines of medicinal plants and fungi. It discusses topics such as the prevention of major neurodegenerative and neurotoxic mechanisms by Centella asiatica; the medicinal properties and therapeutic applications of several mushrooms species found in different parts of the world; and fungal endophytes as a source of bioactive metabolites including anticancer and cardioprotective agents. There are also chapters on strategies for identifying bioactive secondary metabolitesof fungal origin; the use of genomic information to explore the biotechnological potential of medicinal mushrooms; and solid state fermentation of agro-industrial and forestry residues for the production of medicinal mushrooms. It is a valuable resource for the researchers, professionals and students working in the area of medicinal plants and fungi.
- Published
- 2017
46. Health Care for People with Intellectual and Developmental Disabilities Across the Lifespan
- Author
-
I. Leslie Rubin, Joav Merrick, Donald E. Greydanus, Dilip R. Patel, I. Leslie Rubin, Joav Merrick, Donald E. Greydanus, and Dilip R. Patel
- Subjects
- Intellectual disability, People with mental disabilities--Care
- Abstract
This book provides a broad overview of quality health care for people with intellectual and developmental disabilities (IDD). It focuses on providing the reader a practical approach to dealing with the health and well-being of people with IDD in general terms as well as in dealing with specific conditions. In addition, it offers the reader a perspective from many different points of view in the health care delivery system as well as in different parts of the world. This is the 3rd, and much expanded edition, of a text that was first published in 1989 (Lea and Fibiger). The second edition was published in 2006 (Paul Brookes) and has been used as a formal required text in training programs for physicians, nurses and nurse practitioners as well as by administrators who are responsible for programs serving people with IDD. This book is considered the “Bible” in the field of health care for people with IDD since 1989 when the first edition came out.
- Published
- 2016
47. 'I Would Like for My Child to be Happy with His Life': Parental Hopes for Their Children with ASD Across the Lifespan
- Author
-
Finke, Erinn H., Kremkow, Jennifer M.D., Drager, Kathryn D.R., Murillo, Angelique, Richardson, Laura, and Serpentine, Elizabeth C.
- Subjects
Autistic children -- Family -- Social aspects ,Hope -- Social aspects ,Parents -- Beliefs, opinions and attitudes -- Family -- Social aspects ,Parent-child relations ,Health - Abstract
The purpose of this project was to understand the hopes of parents with children with ASD. Particularly understudied are the hopes parents have for long-term outcomes for their child. A cross-sectional focus group design was used and six focus groups were completed. These groups included parents of (1) preschool aged children who were recently diagnosed, (2) children in early elementary school, (3) children in later elementary school, (4) children in middle school, (5) children in high school, and (6) children who are adults with ASD. Results indicated 77.4% of the data were devoted to hopes for the children's independence, happiness, and skill improvement; increased authentic socially significant relationships; and future employment., Author(s): Erinn H. Finke [sup.1] , Jennifer M. D. Kremkow [sup.2] , Kathryn D. R. Drager [sup.3] , Angelique Murillo [sup.3] , Laura Richardson [sup.3] , Elizabeth C. Serpentine [sup.4] [...]
- Published
- 2019
- Full Text
- View/download PDF
48. The Role of Child Problem Behaviors in Autism Spectrum Symptoms and Parenting Stress: A Primary School-Based Study
- Author
-
Siu, Queenie K. Y., Yi, Huso, Chan, Randolph C. H., Chio, Floria H. N., Chan, Dorothy F. Y., and Mak, Winnie W. S.
- Subjects
Health screening -- Usage ,Parenting -- Psychological aspects ,Child behavior -- Psychological aspects ,Structural equation modeling -- Usage ,Pervasive developmental disorders -- Development and progression -- Diagnosis ,Parent-child relations -- Psychological aspects ,Health - Abstract
Parents of children with autism spectrum disorders (ASD) reported higher stress than those of typically developing children. The role of child problem behaviors in the relationship between autism spectrum symptoms and parenting stress is little known. A total of 731 parents of 177 children with ASD and 554 typically developing children in primary schools (6-11 years old) completed an ASD screening survey containing measures of parenting stress and child problem behaviors. While autism spectrum symptoms were positively associated with parenting stress, the relationship was mediated by child problem behaviors. Results suggest neither the severity of autism spectrum symptoms nor knowledge of ASD diagnosis was a primary source of parenting stress. A hypothesized path model was tested using structural equation modeling., Author(s): Queenie K. Y. Siu [sup.1] , Huso Yi [sup.2] , Randolph C. H. Chan [sup.3] , Floria H. N. Chio [sup.4] , Dorothy F. Y. Chan [sup.5] , Winnie [...]
- Published
- 2019
- Full Text
- View/download PDF
49. I Domain Integrins
- Author
-
Donald Gullberg and Donald Gullberg
- Subjects
- Integrins
- Abstract
The integrin family is composed of 24 members and approximately ten years ago (2003) we published a book devoted to the nine I domain integrin subunits. In this second edition, I am pleased that most of the original authors have been able to contribute to the updated version.I domain containing integrins include collagen receptors and leukocyte receptors. In 2003 the knockout mouse phenotypes for all of the I domain integrins had not yet been published; they are now, and are summarized and discussed in this edition.Interestingly, a recent 10 integrin mutation in dogs has indicated that collagen-binding integrins in the musculoskeletal system might have much more severe phenotypes in larger animals/humans compared to the mild integrin phenotypes observed in collagen-binding integrin deficient mice. This finding is further discussed in the book.In the cancer field, the microenvironment is taking center stage, and here collagen receptors on fibroblasts are predicted to play important roles in paracrine signaling, in regulating tissue stiffness and matrix remodeling.New technologies, new mouse models in combination with analyses of I integrins in larger animals/humans are thus predicted to increase our knowledge about this group of receptors. With this in mind we look forward to another 10 years of research with I domain integrins.
- Published
- 2014
50. The Association Between Emotional and Behavioral Problems in Children with Autism Spectrum Disorder and Psychological Distress in Their Parents: A Systematic Review and Meta-analysis
- Author
-
Yorke, Isabel, White, Pippa, Weston, Amelia, Rafla, Monica, Charman, Tony, and Simonoff, Emily
- Subjects
Child health -- Management ,Pervasive developmental disorders -- Development and progression ,Parent-child relations ,Company business management ,Health - Abstract
This review (Prospero Registration Number: CRD42017057915) aimed to systematically identify and summarize existing research on the relationship between additional emotional and behavioral problems (EBP) in children with autism, and parenting stress (PS) and mental health problems (MHP) in their parents. Sixty-seven studies met criteria for inclusion in the review, 61 of which were included in the meta-analysis. Pooled correlation coefficients were in the low to moderate range ( [Formula omitted]). Some evidence for moderation by measurement characteristics was found. Narrative review of concurrent adjusted associations showed some evidence for shared relationships with other factors, most notably ASD severity and parent perception of own parenting. Longitudinal studies showed mixed evidence for bidirectional predictive relationships between child EBP and parent psychological distress variables., Author(s): Isabel Yorke [sup.1] , Pippa White [sup.1] , Amelia Weston [sup.2] , Monica Rafla [sup.1] , Tony Charman [sup.1] , Emily Simonoff [sup.1] Author Affiliations: (Aff1) 0000 0001 2322 [...]
- Published
- 2018
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