7 results on '"Shen, Cheng-Che"'
Search Results
2. Risk of Parkinson’s disease following gout: a population-based retrospective cohort study in Taiwan
- Author
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Hu, Li-Yu, Yang, Albert C., Lee, Shyh-Chyang, You, Zi-Hong, Tsai, Shih-Jen, Hu, Chang-Kuo, and Shen, Cheng-Che
- Published
- 2020
- Full Text
- View/download PDF
3. Comorbidity study of borderline personality disorder: applying association rule mining to the Taiwan national health insurance research database.
- Author
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Cheng-Che Shen, Li-Yu Hu, Ya-Han Hu, Shen, Cheng-Che, Hu, Li-Yu, and Hu, Ya-Han
- Subjects
BORDERLINE personality disorder ,TREATMENT of borderline personality disorder ,NATIONAL health insurance ,PATHOLOGICAL psychology ,INTELLECTUAL disabilities ,PATIENTS ,NATIONAL health services ,DATA mining ,COMORBIDITY ,ACQUISITION of data ,DISEASE prevalence ,RETROSPECTIVE studies ,CASE-control method - Abstract
Background: Borderline personality disorder (BPD) is a complex clinical state with highly polymorphic symptoms and signs. Studies have demonstrated that people with a BPD diagnosis are likely to have numerous co-occurring psychiatric disorders and physical comorbidities. The aim of our study was to obtain further insight about the associations among comorbidities of BPD and to demonstrate the practicality of using association rule mining (ARM) technique in clinical databases.Methods: A retrospective case-control study was conducted on information of 1460 patients (292 BPD patients and 1168 control patients) selected from the Taiwan National Health Insurance Research Database. Information on physical and psychiatric comorbidities, which were diagnosed within 3 years before and after enrollment, was collected. A logistic regression model was used to calculate the odds ratios of comorbidities between patients with and without BPD. ARM technique was used to study the associations of BPD and two or more psychiatric comorbidities.Results: We classified physical comorbidities into 13 categories according to the International Classification of Diseases, Ninth Revision, Clinical Modification system, and the results indicated that the 12 categories were more common in the BPD patients than in the control patients (except congenital anomalies). However, psychiatric comorbidities, including depressive disorder, bipolar disorder, anxiety disorder, sleep disorder, substance use disorder, and mental retardation were more common in the BPD patients than in the control patients. Furthermore, the associations of BPD and two or more comorbidities were evaluated.Conclusion: Most physical and psychiatric disorders were more common in the BPD patients than in the control patients. Because the failure to remit from BPD is associated with suffering from chronic physical conditions and because psychiatric comorbidities may lead to delays in diagnosis of BPD, clinicians caring for people with BPD should be aware of possible comorbidities. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
- View/download PDF
4. Comorbidity study of borderline personality disorder: applying association rule mining to the Taiwan national health insurance research database.
- Author
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Shen CC, Hu LY, and Hu YH
- Subjects
- Adult, Case-Control Studies, Female, Humans, Male, Middle Aged, Prevalence, Retrospective Studies, Taiwan epidemiology, Young Adult, Borderline Personality Disorder epidemiology, Comorbidity, Data Mining methods, Datasets as Topic statistics & numerical data, National Health Programs statistics & numerical data
- Abstract
Background: Borderline personality disorder (BPD) is a complex clinical state with highly polymorphic symptoms and signs. Studies have demonstrated that people with a BPD diagnosis are likely to have numerous co-occurring psychiatric disorders and physical comorbidities. The aim of our study was to obtain further insight about the associations among comorbidities of BPD and to demonstrate the practicality of using association rule mining (ARM) technique in clinical databases., Methods: A retrospective case-control study was conducted on information of 1460 patients (292 BPD patients and 1168 control patients) selected from the Taiwan National Health Insurance Research Database. Information on physical and psychiatric comorbidities, which were diagnosed within 3 years before and after enrollment, was collected. A logistic regression model was used to calculate the odds ratios of comorbidities between patients with and without BPD. ARM technique was used to study the associations of BPD and two or more psychiatric comorbidities., Results: We classified physical comorbidities into 13 categories according to the International Classification of Diseases, Ninth Revision, Clinical Modification system, and the results indicated that the 12 categories were more common in the BPD patients than in the control patients (except congenital anomalies). However, psychiatric comorbidities, including depressive disorder, bipolar disorder, anxiety disorder, sleep disorder, substance use disorder, and mental retardation were more common in the BPD patients than in the control patients. Furthermore, the associations of BPD and two or more comorbidities were evaluated., Conclusion: Most physical and psychiatric disorders were more common in the BPD patients than in the control patients. Because the failure to remit from BPD is associated with suffering from chronic physical conditions and because psychiatric comorbidities may lead to delays in diagnosis of BPD, clinicians caring for people with BPD should be aware of possible comorbidities.
- Published
- 2017
- Full Text
- View/download PDF
5. Risk of uterine, ovarian and breast cancer following pelvic inflammatory disease: a nationwide population-based retrospective cohort study.
- Author
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Shen CC, Hu LY, Yang AC, Chiang YY, Hung JH, and Tsai SJ
- Subjects
- Adult, Breast Neoplasms epidemiology, Case-Control Studies, Female, Follow-Up Studies, Humans, Middle Aged, Ovarian Neoplasms epidemiology, Prognosis, Retrospective Studies, Taiwan epidemiology, Uterine Neoplasms epidemiology, Young Adult, Breast Neoplasms etiology, Ovarian Neoplasms etiology, Pelvic Inflammatory Disease complications, Uterine Neoplasms etiology
- Abstract
Background: Pelvic inflammatory disease (PID) is characterized by infection and inflammation of the upper genital tract in women and is associated with health sequelae. We used a nationwide population-based retrospective cohort study to explore the relationship between PID and the subsequent development of gynecological cancers including ovarian, breast or uterine cancer., Methods: We identified subjects diagnosed with PID between January 1
st , 2000 and December 31st , 2002 in the Taiwan National Health Insurance Research Database. A comparison cohort constructed for patients without PID were matched according to age and sex. All PID patients and control groups were observed until diagnosed with ovarian, breast or uterine cancer, or until death, withdrawal from the NHI system, or until December 31st , 2009., Results: The PID cohort consisted of 32,268 patients, and an equal number of matched controls without PID. The adjusted hazard ratio (HR) of ovarian, breast or uterine cancer in subjects with PID were: HR 1.326 (95 % confidence interval: 0.775-2.269), HR: 1.039 (95 % confidence interval: 0.862-1.252), and HR: 1.439 (95 % confidence interval: 0.853-2.426) respectively in comparison with controls during follow-up., Conclusions: This large nationwide population-based cohort study suggests that there is no increased risk for ovarian, breast or uterine cancer among women who have PID compared to a matching population.- Published
- 2016
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- View/download PDF
6. Increased risk of benign paroxysmal positional vertigo in patients with anxiety disorders: a nationwide population-based retrospective cohort study.
- Author
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Chen ZJ, Chang CH, Hu LY, Tu MS, Lu T, Chen PM, and Shen CC
- Subjects
- Adult, Aged, Comorbidity, Databases, Factual, Female, Humans, Incidence, Male, Middle Aged, Odds Ratio, Retrospective Studies, Risk Factors, Sex Factors, Taiwan epidemiology, Anxiety Disorders epidemiology, Benign Paroxysmal Positional Vertigo epidemiology
- Abstract
Background: The objective of this study was to evaluate the risk of benign peripheral persistent vertigo (BPPV) among patients with anxiety disorders by using the Taiwan National Health Insurance Research Database (NHIRD)., Methods: We conducted a retrospective study of 15,470 participants (7735 anxiety disorder patients and 7735 control patients) selected from the NHIRD. Patients were observed for a maximum of 9 years to determine the rates of newly diagnosed BPPV. A Cox regression model was used to evaluate the risk of BPPV among the patients with anxiety disorders., Results: During the 9-year follow-up period, 178 (2.05 per 1000 person-years) anxiety disorder patients and 71 (0.81 per 1000 person-years) control patients were diagnosed with BPPV. The incidence risk ratio of BPPV between anxiety disorder patients and control patients was 2.52 (95 % confidence interval [CI], 1.90-3.37, P < .001). After adjustment for age, sex, and comorbidities, patients with anxiety disorders were found to be 2.17 times more likely to develop BPPV (95 % CI, 1.63-2.90, P < .001) than the control patients. Furthermore, female sex (HR = 1.81, 95 % CI, 1.31-2.50, P < .001) and cerebrovascular disease (HR = 1.53, 95 % CI, 1.00-2.34, P = .050) were independent risk factors for developing new-onset BPPV in patients with anxiety disorders., Conclusions: Anxiety disorder patients may have an increased risk of developing BPPV, especially those who are female or have cerebrovascular disease.
- Published
- 2016
- Full Text
- View/download PDF
7. Risk of psychiatric disorders following trigeminal neuralgia: a nationwide population-based retrospective cohort study.
- Author
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Wu TH, Hu LY, Lu T, Chen PM, Chen HJ, Shen CC, and Wen CH
- Subjects
- Adult, Aged, Anxiety Disorders epidemiology, Anxiety Disorders etiology, Anxiety Disorders psychology, Cohort Studies, Databases, Factual, Depressive Disorder epidemiology, Depressive Disorder etiology, Depressive Disorder psychology, Female, Follow-Up Studies, Humans, Male, Mental Disorders epidemiology, Middle Aged, Retrospective Studies, Risk Factors, Sleep Wake Disorders epidemiology, Sleep Wake Disorders etiology, Sleep Wake Disorders psychology, Taiwan epidemiology, Trigeminal Neuralgia epidemiology, Mental Disorders etiology, Mental Disorders psychology, Population Surveillance methods, Trigeminal Neuralgia complications, Trigeminal Neuralgia psychology
- Abstract
Background: TN is one of the most common causes of facial pain. A higher prevalence of psychiatric co-morbidities, especially depressive disorder, has been proven in patients with TN; however, a clear temporal-causal relationship between TN and specific psychiatric disorders has not been well established. We performed a nationwide population-based retrospective cohort study to explore the relationship between TN and the subsequent development of psychiatric disorders, including schizophrenia, bipolar disorder, depressive disorder, anxiety disorder, and sleep disorder., Methods: We identified subjects who were newly diagnosed with TN between January 1, 2000 and December 31, 2010 in the Taiwan National Health Insurance Research Database. A comparison cohort was constructed for patients without TN who were matched according to age and sex. All TN and control patients were observed until diagnosed with psychiatric disorders, death, withdrawal from the National Health Institute system, or until December 31, 2010., Results: The TN cohort consisted of 3273 patients, and the comparison cohort consisted of 13,092 matched control patients without TN. The adjusted hazard ratio (aHR) of depressive disorder, anxiety disorder and sleep disorder in subjects with TN was higher than that of the controls during the follow-up [aHR: 2.85 (95% confidence interval: 2.11-3.85), aHR: 2.98 (95% confidence interval: 2.12-4.18) and aHR: 2.17 (95% confidence interval: 1.48-3.19), respectively]., Conclusions: TN might increase the risk of subsequent newly diagnosed depressive disorder, anxiety disorder, and sleep disorder, but not schizophrenia or bipolar disorder. Additional prospective studies are required to confirm these findings.
- Published
- 2015
- Full Text
- View/download PDF
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