Author: "Papadopoulos, Theofilos" / Language: english / Publisher: american chemical society - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Papadopoulos, Theofilos" Language english Publisher american chemical society

Author: Frantzi, Maria, Zoidakis, Jerome, Papadopoulos, Theofilos, Zürbig, Petra, Katafigiotis, Ioannis, Stravodimos, Konstantinos, Lazaris, Andreas, Giannopoulou, Ioanna, Ploumidis, Achilles, Mischak, Harald, Mullen, William, and Vlahou, Antonia
Published: 2013
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Author: Papadopoulos, Theofilos, Kelly, Julie A., and Bauer, Karl
Subjects: *BINDING sites, *THYROTROPIN releasing factor, *PEPTIDASE, *ENZYME inhibitors
Abstract: Examines the organization of the active site of the thyrotropin-releasing hormone-degrading ectoenzyme (TRH-DE), a TRH-specific peptidase that catalyzes the inactivation of the peptidergic signal substance TRH. Enzymatic activity of wild-type and mutated TRH-DEs and the inhibitory potencies of various classes of inhibitors; Differences in the evolution of the active sites and in the mechanism of action between TRH-DE and APA.
Published: 2001
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