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Your search keyword '"Jørgensen, Erik"' showing total 623 results
Start Over Author "Jørgensen, Erik" Publication Year Range Last 50 years Language english
623 results on '"Jørgensen, Erik"'

2. The importance of nonobstructive plaque characteristics in symptomatic and asymptomatic coronary artery disease

Author

Kofoed, Klaus F., Nordestgaard, Børge, Køber, Lars V., Kühl, J. Tobias, Fuchs, Andreas, Sigvardsen, Per E., Sørgaard, Mathias, de Knegt, Martina C., Norsk, Jakob, Frestad, Daria, Mejdahl, Mads, Elming, Marie, Sørensen, Samuel Kiil, Hindsøe, Louise, Thomsen, Anna Foged, Udholm, Patricia Martens, Pihl, Christian, Nilsson, Julia, Byrne, Christina, Knudsen, Andreas Dehlbæk, Haugen, Morten, Windfeld-Mathiasen, Josefine, Laura Wiegandt, Yaffah Tamar, Pham, Michael H.C., Ballegaard, Christian, Arnaa, Kirsten, Møller, Christina, Thrysøe, Kirsten, Linde, Jesper J., Hove, Jens D., Jensen, Gorm B., Kelbæk, Henning, Nielsen, Walter, Trysøe, Kirsten, Bock-Pedersen, Tina, Hansen, Bettina, Kløvgaard, Lene, Holmvang, Lene, Engstrøm, Thomas, Helquist, Steffen, Jørgensen, Erik, Petersen, Frans, Saunamaki, Kari, Clemmensen, Peter, Høfsten, Dan E., Sadjadieh, Golnaz, Laursen, Peter Nørkjær, Petersen, Christian Torp, Hansen, Peter Riis, Gislason, Gunnar, Abildgaard, Ulrik, Jensen, Jan Skov, Galatius, Søren, Fritz-Hansen, Thomas, Bech, Jan, Wachtell, Christian, Madsen, Jan Kyst, Smedegaard, Lærke, Özcan, Cengiz, Heitmann, Merete, Svendsen, Ida Hastrup, Nielsen, Olav Wendelboe, Kristiansen, Ole, Bjerre, Andreas Fabricius, Dixen, Ulrik, Madsen, Johnny Koertz, Fornitz, Gitte Gleerup, Raymond, Ilan, Abdulla, Jawdat, Lyngbæk, Stig, Steffensen, Rolf, Jurlander, Birgit, Kragelund, Charlotte, Dominguez, Helena, Schou, Morten, Elming, Hanne, Therkelsen, Susette, Jensen, Andreas K., Hansen, Peter R., and Nordestgaard, Børge G.

Published
2024
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5. Prognostic Value of Coronary CT Angiography in Patients With Non–ST-Segment Elevation Acute Coronary Syndromes

Author

Kofoed, Klaus F., Engstrøm, Thomas, Sigvardsen, Per E., Linde, Jesper J., Torp-Pedersen, Christian, de Knegt, Martina, Hansen, Peter R., Fritz-Hansen, Thomas, Bech, Jan, Heitmann, Merete, Nielsen, Olav W., Høfsten, Dan, Kühl, Jørgen T., Raymond, Ilan E., Kristiansen, Ole P., Svendsen, Ida H., Domínguez Vall-Lamora, M.H., Kragelund, Charlotte, Hove, Jens D., Jørgensen, Tem, Fornitz, Gitte G., Steffensen, Rolf, Jurlander, Birgit, Abdulla, Jawdat, Lyngbæk, Stig, Elming, Hanne, Therkelsen, Susette K., Jørgensen, Erik, Kløvgaard, Lene, Bang, Lia E., Helqvist, Steffen, Galatius, Søren, Pedersen, Frants, Abildgaard, Ulrik, Clemmensen, Peter, Saunamäki, Kari, Holmvang, Lene, Gislason, Gunnar, Kelbæk, Henning, and Køber, Lars V.

Published
2021
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8. Complete Revascularization Versus Culprit Lesion Only in Patients With ST-Segment Elevation Myocardial Infarction and Multivessel Disease: A DANAMI-3–PRIMULTI Cardiac Magnetic Resonance Substudy

Author

Kyhl, Kasper, Ahtarovski, Kiril Aleksov, Nepper-Christensen, Lars, Ekström, Kathrine, Ghotbi, Adam Ali, Schoos, Mikkel, Göransson, Christoffer, Bertelsen, Litten, Helqvist, Steffen, Holmvang, Lene, Jørgensen, Erik, Pedersen, Frants, Saunamäki, Kari, Clemmensen, Peter, De Backer, Ole, Høfsten, Dan Eik, Køber, Lars, Kelbæk, Henning, Vejlstrup, Niels, Lønborg, Jacob, and Engstrøm, Thomas

Published
2019
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9. Bleeding Events After ST-segment Elevation Myocardial Infarction in Patients Randomized to an All-comer Clinical Trial Compared With Unselected Patients

Author

Sadjadieh, Golnaz, Engstrøm, Thomas, Høfsten, Dan Eik, Helqvist, Steffen, Køber, Lars, Pedersen, Frants, Laursen, Peter Nørkjær, Andersson, Hedvig Bille, Nepper-Christensen, Lars, Clemmensen, Peter, Sørensen, Rikke, Jørgensen, Erik, Saunamäki, Kari, Tilsted, Hans-Henrik, Kelbæk, Henning, and Holmvang, Lene

Published
2018
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11. Relation of Bleeding Events to Mortality in Patients With ST-Segment Elevation Myocardial Infarction Treated by Percutaneous Coronary Intervention (a DANAMI-3 Substudy)

Author

Sadjadieh, Golnaz, Engstrøm, Thomas, Helqvist, Steffen, Høfsten, Dan Eik, Køber, Lars, Pedersen, Frants, Laursen, Peter Nørkjær, Nepper-Christensen, Lars, Clemmensen, Peter, Møller-Helgestad, Ole Kristian, Sørensen, Rikke, Ravkilde, Jan, Terkelsen, Christian Juhl, Jørgensen, Erik, Saunamäki, Kari, Tilsted, Hans-Henrik, Kelbæk, Henning, and Holmvang, Lene

Published
2018
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17. Comparison of Outcome of Patients With ST-Segment Elevation Myocardial Infarction and Complete Versus Incomplete ST-Resolution Before Primary Percutaneous Coronary Intervention

Author

Lønborg, Jacob, Kelbæk, Henning, Holmvang, Lene, Helqvist, Steffen, Vejlstrup, Niels, Jørgensen, Erik, Saunamäki, Kari, Dridi, Nadia P., Kløvgaard, Lene, Kaltoft, Anne, Bøtker, Hans-Erik, Lassen, Jens F., Clemmensen, Peter, Terkelsen, Christian Juhl, and Engstrøm, Thomas

Published
2016
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18. Deferred versus conventional stent implantation in patients with ST-segment elevation myocardial infarction (DANAMI 3-DEFER): an open-label, randomised controlled trial

Author

Kelbæk, Henning, Høfsten, Dan Eik, Køber, Lars, Helqvist, Steffen, Kløvgaard, Lene, Holmvang, Lene, Jørgensen, Erik, Pedersen, Frants, Saunamäki, Kari, De Backer, Ole, Bang, Lia E, Kofoed, Klaus F, Lønborg, Jacob, Ahtarovski, Kiril, Vejlstrup, Niels, Bøtker, Hans E, Terkelsen, Christian J, Christiansen, Evald H, Ravkilde, Jan, Tilsted, Hans-Henrik, Villadsen, Anton B, Aarøe, Jens, Jensen, Svend E, Raungaard, Bent, Jensen, Lisette O, Clemmensen, Peter, Grande, Peer, Madsen, Jan K, Torp-Pedersen, Christian, and Engstrøm, Thomas

Published
2016
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21. Early Versus Standard Care Invasive Examination and Treatment of Patients With Non-ST-Segment Elevation Acute Coronary Syndrome: VERDICT Randomized Controlled Trial

Author

Kofoed, Klaus F., Kelbæk, Henning, Hansen, Peter Riis, Torp-Pedersen, Christian, Høfsten, Dan, Kløvgaard, Lene, Holmvang, Lene, Helqvist, Steffen, Jørgensen, Erik, Galatius, Søren, Pedersen, Frants, Bang, Lia, Saunamaki, Kari, Clemmensen, Peter, Linde, Jesper J., Heitmann, Merete, Wendelboe Nielsen, Olav, Raymond, Ilan E., Kristiansen, Ole Peter, Svendsen, Ida Hastrup, Bech, Jan, Dominguez Vall-Lamora, Maria Helena, Kragelund, Charlotte, Hansen, Thomas Fritz, Dahlgaard Hove, Jens, Jørgensen, Tem, Fornitz, Gitte G., Steffensen, Rolf, Jurlander, Birgit, Abdulla, Jawdat, Lyngbæk, Stig, Elming, Hanne, Therkelsen, Susette Krohn, Abildgaard, Ulrik, Jensen, Jan Skov, Gislason, Gunnar, Køber, Lars V., and Engstrøm, Thomas

Published
2018
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22. Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI-3—PRIMULTI): an open-label, randomised controlled trial

Author

Engstrøm, Thomas, Kelbæk, Henning, Helqvist, Steffen, Høfsten, Dan Eik, Kløvgaard, Lene, Holmvang, Lene, Jørgensen, Erik, Pedersen, Frants, Saunamäki, Kari, Clemmensen, Peter, De Backer, Ole, Ravkilde, Jan, Tilsted, Hans-Henrik, Villadsen, Anton Boel, Aarøe, Jens, Jensen, Svend Eggert, Raungaard, Bent, and Køber, Lars

Published
2015
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24. Impact of Health Care System Delay in Patients With ST-Elevation Myocardial Infarction on Return to Labor Market and Work Retirement

Author

Laut, Kristina Grønborg, Hjort, Jacob, Engstrøm, Thomas, Jensen, Lisette Okkels, Tilsted Hansen, Hans-Henrik, Jensen, Jan Skov, Pedersen, Frants, Jørgensen, Erik, Holmvang, Lene, Pedersen, Alma Becic, Christensen, Erika Frischknecht, Lippert, Freddy, Lang-Jensen, Torsten, Jans, Henning, Hansen, Poul Anders, Trautner, Sven, Kristensen, Steen Dalby, Lassen, Jens Flensted, Lash, Timothy L., Clemmensen, Peter, and Terkelsen, Christian Juhl

Published
2014
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29. Cryopreserved Off‐the‐Shelf Allogeneic Adipose‐Derived Stromal Cells for Therapy in Patients with Ischemic Heart Disease and Heart Failure—A Safety Study

Author

Kastrup, Jens, Haack‐Sørensen, Mandana, Juhl, Morten, Harary Søndergaard, Rebekka, Follin, Bjarke, Drozd Lund, Lisbeth, Mønsted Johansen, Ellen, Ali Qayyum, Abbas, Bruun Mathiasen, Anders, Jørgensen, Erik, Helqvist, Steffen, Jørgen Elberg, Jens, Bruunsgaard, Helle, and Ekblond, Annette

Published
2017
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30. Effect of allogeneic adipose tissue‐derived mesenchymal stromal cell treatment in chronic ischaemic heart failure with reduced ejection fraction – the SCIENCE trial.

Author

Qayyum, Abbas Ali, van Klarenbosch, Bas, Frljak, Sabina, Cerar, Andraz, Poglajen, Gregor, Traxler‐Weidenauer, Denise, Nadrowski, Pawel, Paitazoglou, Christina, Vrtovec, Bojan, Bergmann, Martin W., Chamuleau, Steven A. J., Wojakowski, Wojtek, Gyöngyösi, Mariann, Kraaijeveld, Adriaan, Hansen, Kristian Schultz, Vrangbæk, Karsten, Jørgensen, Erik, Helqvist, Steffen, Joshi, Francis Richard, and Johansen, Ellen Mønsted

Subjects
BRAIN natriuretic factor, STROMAL cells, HEART failure, VENTRICULAR ejection fraction, ADIPOSE tissue diseases, CARDIAC patients
Abstract

Aims: The aim of the SCIENCE trial was to investigate whether a single treatment with direct intramyocardial injections of adipose tissue‐derived mesenchymal stromal cells (CSCC_ASCs) was safe and improved cardiac function in patients with chronic ischaemic heart failure with reduced ejection fraction (HFrEF). Methods and results: The study was a European multicentre, double‐blind, placebo‐controlled phase II trial using allogeneic CSCC_ASCs from healthy donors or placebo (2:1 randomization). Main inclusion criteria were New York Heart Association (NYHA) class II–III, left ventricular ejection fraction (LVEF) <45%, and N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) levels >300 pg/ml. CSCC_ASCs or placebo (isotonic saline) were injected directly into viable myocardium. The primary endpoint was change in left ventricular end‐systolic volume (LVESV) at 6‐month follow‐up measured by echocardiography. A total of 133 symptomatic HFrEF patients were included. The treatment was safe without any drug‐related severe adverse events or difference in cardiac‐related adverse events during a 3‐year follow‐up period. There were no significant differences between groups during follow‐up in LVESV (0.3 ± 5.0 ml, p = 0.945), nor in secondary endpoints of left ventricular end‐diastolic volume (−2.0 ± 6.0 ml, p = 0.736) and LVEF (−1.6 ± 1.0%, p = 0.119). The NYHA class improved slightly within the first year in both groups without any difference between groups. There were no changes in 6‐min walk test, NT‐proBNP, C‐reactive protein or quality of life the first year in any groups. Conclusion: The SCIENCE trial demonstrated safety of intramyocardial allogeneic CSCC_ASC therapy in patients with chronic HFrEF. However, it was not possible to improve the pre‐defined endpoints and induce restoration of cardiac function or clinical symptoms. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Danish phase II trial using adipose tissue derived mesenchymal stromal cells for patients with ischaemic heart failure.

Author

Qayyum, Abbas Ali, Mouridsen, Mette, Nilsson, Brian, Gustafsson, Ida, Schou, Morten, Nielsen, Olav Wendelboe, Hove, Jens Dahlgaard, Mathiasen, Anders Bruun, Jørgensen, Erik, Helqvist, Steffen, Joshi, Francis Richard, Johansen, Ellen Mønsted, Follin, Bjarke, Juhl, Morten, Højgaard, Lisbeth Drozd, Haack‐Sørensen, Mandana, Ekblond, Annette, and Kastrup, Jens

Subjects
HEART failure, HEART failure patients, STROMAL cells, ADIPOSE tissues, VENTRICULAR ejection fraction, FAT cells
Abstract

Aims: Patients suffering from chronic ischaemic heart failure with reduced left ventricular ejection fraction (HFrEF) have reduced quality‐of‐life, repetitive hospital admissions, and reduced life expectancy. Allogeneic cell therapy is currently investigated as a potential treatment option after initially encouraging results from clinical autologous and allogeneic trials in patients with HFrEF. We aimed to investigate the allogeneic Cardiology Stem Cell Centre Adipose tissue derived mesenchymal Stromal Cell product (CSCC_ASC) as an add‐on therapy in patients with chronic HFrEF. Methods and results: This is a Danish multi‐centre double‐blinded placebo‐controlled phase II study with direct intra‐myocardial injections of allogeneic CSCC_ASC. A total of 81 HFrEF patients were included and randomized 2:1 to CSCC_ASC or placebo injections. The inclusion criteria were reduced left ventricular ejection fraction (LVEF ≤ 45%), New York Heart Association (NYHA) class II‐III despite optimal anti‐congestive heart failure medication and no further revascularization options. Injections of 0.3 mL CSCC_ASC (total cell dose 100 × 106 ASCs) (n = 54) or isotonic saline (n = 27) were performed into the viable myocardium in the border zone of infarcted tissue using the NOGA Myostar® catheter (Biological Delivery System, Cordis, Johnson & Johnson, USA). The primary endpoint, left ventricular end systolic volume (LVESV), was evaluated at 6‐month follow‐up. The safety was measured during a 3‐years follow‐up period. Results: Mean age was 67.0 ± 9.0 years and 66.6 ± 8.1 years in the ASC and placebo groups, respectively. LVESV was unchanged from baseline to 6‐month follow‐up in the ASC (125.7 ± 68.8 mL and 126.3 ± 72.5 mL, P = 0.827) and placebo (134.6 ± 45.8 mL and 135.3 ± 49.6 mL, P = 0.855) group without any differences between the groups (0.0 mL (95% CI −9.1 to 9.0 mL, P = 0.992). Neither were there significant changes in left ventricular end diastolic volume or LVEF within the two groups or between groups −5.7 mL (95% CI −16.7 to 5.3 mL, P = 0.306) and −1.7% (95% CI −4.4. to 1.0, P = 0.212), respectively). NYHA classification and 6‐min walk test did not alter significantly in the two groups (P > 0.05). The quality‐of‐life, total symptom, and overall summary score improved significantly only in the ASC group but not between groups. There were 24 serious adverse events (SAEs) in the ASC group and 11 SAEs in the placebo group without any significant differences between the two groups at 1‐year follow‐up. Kaplan–Meier plot using log‐rank test of combined cardiac events showed an overall mean time to event of 30 ± 2 months in the ASC group and 29 ± 2 months in the placebo group without any differences between the groups during the 3 years follow‐up period (P = 0.994). Conclusions: Intramyocardial CSCC_ASC injections in patients with chronic HFrEF were safe but did not improve myocardial function or structure, nor clinical symptoms. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Long-Term Outcome After Drug-Eluting Versus Bare-Metal Stent Implantation in Patients With ST-Segment Elevation Myocardial Infarction: 5 Years Follow-Up From the Randomized DEDICATION Trial (Drug Elution and Distal Protection in Acute Myocardial Infarction)

Author

Holmvang, Lene, Kelbæk, Henning, Kaltoft, Anne, Thuesen, Leif, Lassen, Jens Flensted, Clemmensen, Peter, Kløvgaard, Lene, Engstrøm, Thomas, Bøtker, Hans E., Saunamäki, Kari, Krusell, Lars R., Jørgensen, Erik, Tilsted, Hans-Henrik, Christiansen, Evald H., Ravkilde, Jan, Køber, Lars, Kofoed, Klaus Fuglsang, Terkelsen, Christian J., and Helqvist, Steffen

Published
2013
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35. Association Between Early Q Waves and Reperfusion Success in Patients With ST-Segment–Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention: A Cardiac Magnetic Resonance Imaging Study

Author

Topal, Divan Gabriel, Lønborg, Jacob, Ahtarovski, Kiril Aleksov, Nepper-Christensen, Lars, Helqvist, Steffen, Holmvang, Lene, Pedersen, Frants, Clemmensen, Peter, Saünamaki, Kari, Jørgensen, Erik, Kyhl, Kasper, Ghotbi, Ali, Schoos, Mikkel Malby, Göransson, Christoffer, Bertelsen, Litten, Høfsten, Dan, Køber, Lars, Kelbæk, Henning, Vejlstrup, Niels, and Engstrøm, Thomas

Published
2017
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46. Usefulness of Preprocedure High-Sensitivity C-Reactive Protein to Predict Death, Recurrent Myocardial Infarction, and Stent Thrombosis According to Stent Type in Patients With ST-Segment Elevation Myocardial Infarction Randomized to Bare Metal or Drug-Eluting Stenting During Primary Percutaneous Coronary Intervention

Author

Schoos, Mikkel Malby, Kelbæk, Henning, Kofoed, Klaus F., Køber, Lars, Kløvgaard, Lene, Helqvist, Steffen, Engstrøm, Thomas, Saunamäki, Kari, Jørgensen, Erik, Holmvang, Lene, and Clemmensen, Peter

Published
2011
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