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247 results on '"Johnson, Warren E."'

2. The evolutionary history of extinct and living lions

Author

de Manuel, Marc, Barnett, Ross, Sandoval-Velasco, Marcela, Yamaguchi, Nobuyuki, Vieira, Filipe Garrett, Mendoza, M. Lisandra Zepeda, Liu, Shiping, Martin, Michael D., Sinding, Mikkel-Holger S., Mak, Sarah S. T., Carøe, Christian, Liu, Shanlin, Guo, Chunxue, Zheng, Jiao, Zazula, Grant, Baryshnikov, Gennady, Eizirik, Eduardo, Koepfli, Klaus-Peter, Johnson, Warren E., Antunes, Agostinho, Sicheritz-Ponten, Thomas, Gopalakrishnan, Shyam, Larson, Greger, Yang, Huanming, O’Brien, Stephen J., Hansen, Anders J., Zhang, Guojie, Marques-Bonet, Tomas, and Gilbert, M. Thomas P.

Published
2020

3. Towards complete and error-free genome assemblies of all vertebrate species

Author

Rhie, Arang, McCarthy, Shane A., Fedrigo, Olivier, Damas, Joana, Formenti, Giulio, Koren, Sergey, Uliano-Silva, Marcela, Chow, William, Fungtammasan, Arkarachai, Kim, Juwan, Lee, Chul, Ko, Byung June, Chaisson, Mark, Gedman, Gregory L., Cantin, Lindsey J., Thibaud-Nissen, Francoise, Haggerty, Leanne, Bista, Iliana, Smith, Michelle, Haase, Bettina, Mountcastle, Jacquelyn, Winkler, Sylke, Paez, Sadye, Howard, Jason, Vernes, Sonja C., Lama, Tanya M., Grutzner, Frank, Warren, Wesley C., Balakrishnan, Christopher N., Burt, Dave, George, Julia M., Biegler, Matthew T., Iorns, David, Digby, Andrew, Eason, Daryl, Robertson, Bruce, Edwards, Taylor, Wilkinson, Mark, Turner, George, Meyer, Axel, Kautt, Andreas F., Franchini, Paolo, Detrich, III, H. William, Svardal, Hannes, Wagner, Maximilian, Naylor, Gavin J. P., Pippel, Martin, Malinsky, Milan, Mooney, Mark, Simbirsky, Maria, Hannigan, Brett T., Pesout, Trevor, Houck, Marlys, Misuraca, Ann, Kingan, Sarah B., Hall, Richard, Kronenberg, Zev, Sović, Ivan, Dunn, Christopher, Ning, Zemin, Hastie, Alex, Lee, Joyce, Selvaraj, Siddarth, Green, Richard E., Putnam, Nicholas H., Gut, Ivo, Ghurye, Jay, Garrison, Erik, Sims, Ying, Collins, Joanna, Pelan, Sarah, Torrance, James, Tracey, Alan, Wood, Jonathan, Dagnew, Robel E., Guan, Dengfeng, London, Sarah E., Clayton, David F., Mello, Claudio V., Friedrich, Samantha R., Lovell, Peter V., Osipova, Ekaterina, Al-Ajli, Farooq O., Secomandi, Simona, Kim, Heebal, Theofanopoulou, Constantina, Hiller, Michael, Zhou, Yang, Harris, Robert S., Makova, Kateryna D., Medvedev, Paul, Hoffman, Jinna, Masterson, Patrick, Clark, Karen, Martin, Fergal, Howe, Kevin, Flicek, Paul, Walenz, Brian P., Kwak, Woori, Clawson, Hiram, Diekhans, Mark, Nassar, Luis, Paten, Benedict, Kraus, Robert H. S., Crawford, Andrew J., Gilbert, M. Thomas P., Zhang, Guojie, Venkatesh, Byrappa, Murphy, Robert W., Koepfli, Klaus-Peter, Shapiro, Beth, Johnson, Warren E., Di Palma, Federica, Marques-Bonet, Tomas, Teeling, Emma C., Warnow, Tandy, Graves, Jennifer Marshall, Ryder, Oliver A., Haussler, David, O’Brien, Stephen J., Korlach, Jonas, Lewin, Harris A., Howe, Kerstin, Myers, Eugene W., Durbin, Richard, Phillippy, Adam M., and Jarvis, Erich D.

Published
2021
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4. History of Diversification and Adaptation from North to South Revealed by Genomic Data: Guanacos from the Desert to Sub-Antarctica.

Author

León, Fabiola, Pizarro, Eduardo J, Noll, Daly, Pertierra, Luis R, Gonzalez, Benito A, Johnson, Warren E, Marín, Juan Carlos, and Vianna, Juliana A

Subjects
ANTHROPOGENIC effects on nature, EXTREME environments, DESERTS, GENETIC variation, SUBSPECIES, UNGULATES, PHYSIOLOGICAL adaptation
Abstract

The increased availability of quality genomic data has greatly improved the scope and resolution of our understanding of the recent evolutionary history of wild species adapted to extreme environments and their susceptibility to anthropogenic impacts. The guanaco (Lama guanicoe), the largest wild ungulate in South America, is a good example. The guanaco is well adapted to a wide range of habitats, including the Sechura Desert, the high Andes Mountains to the north, and the extreme temperatures and conditions of Navarino Island to the south. Guanacos also have a long history of overexploitation by humans. To assess the evolutionary impact of these challenging habitats on the genomic diversity, we analyzed 38 genomes (∼10 to 16×) throughout their extensive latitudinal distribution from the Sechura and Atacama Desert to southward into Tierra del Fuego Island. These included analyses of patterns of unique differentiation in the north and geographic region further south with admixture among L. g. cacsilensis and L. g. guanicoe. Our findings provide new insights on the divergence of the subspecies ∼800,000 yr BP and document two divergent demographic trajectories and to the initial expansion of guanaco into the more southern portions of the Atacama Desert. Patagonian guanacos have experienced contemporary reductions in effective population sizes, likely the consequence of anthropogenic impacts. The lowest levels of genetic diversity corresponded to their northern and western limits of distribution and some varying degrees of genetic differentiation. Adaptive genomic diversity was strongly linked with environmental variables and was linked with colonization toward the south followed by adaptation. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Earth BioGenome Project : Sequencing life for the future of life

Author

Lewin, Harris A., Robinson, Gene E., Kress, W. John, Baker, William J., Coddington, Jonathan, Crandall, Keith A., Durbin, Richard, Edwards, Scott V., Forest, Félix, Gilbert, M. Thomas P., Goldstein, Melissa M., Grigoriev, Igor V., Hackett, Kevin J., Haussler, David, Jarvis, Erich D., Johnson, Warren E., Patrinos, Aristides, Richards, Stephen, Castilla-Rubio, Juan Carlos, van Sluys, Marie-Anne, Soltis, Pamela S., Xu, Xun, Yang, Huanming, and Zhang, Guojie

Published
2018

10. Puma genomes from North and South America provide insights into the genomic consequences of inbreeding

Author

Saremi, Nedda F., Supple, Megan A., Byrne, Ashley, Cahill, James A., Coutinho, Luiz Lehmann, Dalén, Love, Figueiró, Henrique V., Johnson, Warren E., Milne, Heather J., O’Brien, Stephen J., O’Connell, Brendan, Onorato, David P., Riley, Seth P. D., Sikich, Jeff A., Stahler, Daniel R., Villela, Priscilla Marqui Schmidt, Vollmers, Christopher, Wayne, Robert K., Eizirik, Eduardo, Corbett-Detig, Russell B., Green, Richard E., Wilmers, Christopher C., and Shapiro, Beth

Published
2019
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15. Chromosome-length genome assembly and karyotype of the endangered black-footed ferret (Mustela nigripes).

Author

Kliver, Sergei, Houck, Marlys L, Perelman, Polina L, Totikov, Azamat, Tomarovsky, Andrey, Dudchenko, Olga, Omer, Arina D, Colaric, Zane, Weisz, David, Aiden, Erez Lieberman, Chan, Saki, Hastie, Alex, Komissarov, Aleksey, Ryder, Oliver A, Graphodatsky, Alexander, Johnson, Warren E, Maldonado, Jesús E, Pukazhenthi, Budhan S, Marinari, Paul E, and Wildt, David E

Subjects
KARYOTYPES, FERRET, GENOMES, ENDANGERED species, CHROMOSOMES, DISEASE susceptibility
Abstract

The black-footed ferret (Mustela nigripes) narrowly avoided extinction to become an oft-cited example of the benefits of intensive management, research, and collaboration to save a species through ex situ conservation breeding and reintroduction into its former range. However, the species remains at risk due to possible inbreeding, disease susceptibility, and multiple fertility challenges. Here, we report the de novo genome assembly of a male black-footed ferret generated through a combination of linked-read sequencing, optical mapping, and Hi-C proximity ligation. In addition, we report the karyotype for this species, which was used to anchor and assign chromosome numbers to the chromosome-length scaffolds. The draft assembly was ~2.5 Gb in length, with 95.6% of it anchored to 19 chromosome-length scaffolds, corresponding to the 2n = 38 chromosomes revealed by the karyotype. The assembly has contig and scaffold N50 values of 148.8 kbp and 145.4 Mbp, respectively, and is up to 96% complete based on BUSCO analyses. Annotation of the assembly, including evidence from RNA-seq data, identified 21,406 protein-coding genes and a repeat content of 37.35%. Phylogenomic analyses indicated that the black-footed ferret diverged from the European polecat/domestic ferret lineage 1.6 million yr ago. This assembly will enable research on the conservation genomics of black-footed ferrets and thereby aid in the further restoration of this endangered species. [ABSTRACT FROM AUTHOR]

Published
2023
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16. Comparative genomics reveals insights into avian genome evolution and adaptation

Author

Zhang, Guojie, Li, Cai, Li, Qiye, Li, Bo, Larkin, Denis M., Lee, Chul, Storz, Jay F., Antunes, Agostinho, Greenwold, Matthew J., Meredith, Robert W., Ödeen, Anders, Cui, Jie, Zhou, Qi, Xu, Luohao, Pan, Hailin, Wang, Zongji, Jin, Lijun, Zhang, Pei, Hu, Haofu, Yang, Wei, Hu, Jiang, Xiao, Jin, Yang, Zhikai, Liu, Yang, Xie, Qiaolin, Yu, Hao, Lian, Jinmin, Wen, Ping, Zhang, Fang, Li, Hui, Zeng, Yongli, Xiong, Zijun, Liu, Shiping, Zhou, Long, Huang, Zhiyong, An, Na, Wang, Jie, Zheng, Qiumei, Xiong, Yingqi, Wang, Guangbiao, Wang, Bo, Wang, Jingjing, Fan, Yu, da Fonseca, Rute R., Alfaro-Núñez, Alonzo, Schubert, Mikkel, Orlando, Ludovic, Mourier, Tobias, Howard, Jason T., Ganapathy, Ganeshkumar, Pfenning, Andreas, Whitney, Osceola, Rivas, Miriam V., Hara, Erina, Smith, Julia, Farré, Marta, Narayan, Jitendra, Slavov, Gancho, Romanov, Michael N, Borges, Rui, Machado, João Paulo, Khan, Imran, Springer, Mark S., Gatesy, John, Hoffmann, Federico G., Opazo, Juan C., Håstad, Olle, Sawyer, Roger H., Kim, Heebal, Kim, Kyu-Won, Kim, Hyeon Jeong, Cho, Seoae, Li, Ning, Huang, Yinhua, Bruford, Michael W., Zhan, Xiangjiang, Dixon, Andrew, Bertelsen, Mads F., Derryberry, Elizabeth, Warren, Wesley, Wilson, Richard K, Li, Shengbin, Ray, David A., Green, Richard E., O'Brien, Stephen J., Griffin, Darren, Johnson, Warren E., Haussler, David, Ryder, Oliver A., Willerslev, Eske, Graves, Gary R., Alström, Per, Fjeldså, Jon, Mindell, David P., Edwards, Scott V., Braun, Edward L., Rahbek, Carsten, Burt, David W., Houde, Peter, Zhang, Yong, Yang, Huanming, Wang, Jian, Consortium, Avian Genome, Jarvis, Erich D., Gilbert, M. Thomas P., and Wang, Jun

Published
2014

18. Assessing patterns of genetic diversity and connectivity among guanacos (Lama guanicoe) in the Bolivian Chaco: implications for designing management strategies.

Author

Mesas, Andrés, Cuéllar-Soto, Erika, Romero, Karina, Zegers, Trinidad, Varas, Valeria, González, Benito A., Johnson, Warren E., and Marín, Juan C.

Subjects
GENETIC variation, ENDANGERED species, MICROSATELLITE repeats, INBREEDING, MITOCHONDRIAL DNA, GENE flow, HAPLOTYPES
Abstract

Although guanacos (Lama guanicoe) are widely distributed throughout much of their historic range, they are often restricted to small, isolated populations that are at risk of inbreeding and loss of genetic diversity. Here we document and interpret baseline patterns of genetic variation in a guanaco population inhabiting in the Bolivian Chaco that is threatened by hunting and habitat degradation. The region, once open grasslands, is dominated by dense shrubs, the result of livestock grazing. The most-recent census identified only 74 individuals and is designated as at 'risk of extinction' by the Bolivian government. We assessed the population's genetic health and uniqueness from the genetic patterns of 16 microsatellite loci, the Hyper-variable Domain I of the mitochondrial Control Region and SRY gene with 29 fecal samples. We identified 19 male and 10 female unique individuals. Microsatellite variation (Ho = 0.64) was similar to larger, less-isolated populations. However, the estimated effective population size was low and consistent with the continuing loss of allelic variation. The two observed mtDNA haplotypes are common in other L. g. guanicoe populations. Although we documented moderate genetic diversity, gene flow among Bolivian and Paraguayan guanaco Chaco populations should be assessed and integrated into explicit conservation management plans. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Genetic Restoration of the Florida Panther

Author

Johnson, Warren E., Onorato, David P., Roelke, Melody E., Land, E. Darrell, Cunningham, Mark, Belden, Robert C., McBride, Roy, Jansen, Deborah, Lotz, Mark, Shindle, David, Howard, JoGayle, Wildt, David E., Penfold, Linda M., Hostetler, Jeffrey A., Oli, Madan K., and O'Brien, Stephen J.

Published
2010

24. The near Eastern Origin of Cat Domestication

Author

Driscoll, Carlos A., Menotti-Raymond, Marilyn, Roca, Alfred L., Hupe, Karsten, Johnson, Warren E., Geffen, Eli, Harley, Eric H., Delibes, Miguel, Pontier, Dominique, Kitchener, Andrew C., Yamaguchi, Nobuyuki, O'Brien, Stephen J., and Macdonald, David W.

Published
2007
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33. Comparative genomics uncovers the evolutionary history, demography, and molecular adaptations of South American canids.

Author

Chavez, Daniel E., Gronau, Ilan, Hains, Taylor, Dikow, Rebecca B., Frandsen, Paul B., Figueiró, Henrique V., Garcez, Fabrício S., Tchaicka, Ligia, de Paula, Rogério C., Rodrigues, Flávio H. G., Jorge, Rodrigo S. P., Lima, Edson S., Songsasen, Nucharin, Johnson, Warren E., Eizirik, Eduardo, Koepfli, Klaus-Peter, and Wayne, Robert K.

Subjects
CANIDAE, COMPARATIVE genomics, SHORT-chain fatty acids, DEMOGRAPHY, GENETIC variation
Abstract

The remarkable radiation of South American (SA) canids produced 10 extant species distributed across diverse habitats, including disparate forms such as the short-legged, hypercarnivorous bush dog and the long-legged, largely frugivorous maned wolf. Despite considerable research spanning nearly two centuries, many aspects of their evolutionary history remain unknown. Here, we analyzed 31 whole genomes encompassing all extant SA canid species to assess phylogenetic relationships, interspecific hybridization, historical demography, current genetic diversity, and the molecular bases of adaptations in the bush dog and maned wolf. We found that SA canids originated from a single ancestor that colonized South America 3.9 to 3.5 Mya, followed by diversification east of the Andes and then a single colonization event and radiation of Lycalopex species west of the Andes. We detected extensive historical gene flow between recently diverged lineages and observed distinct patterns of genomic diversity and demographic history in SA canids, likely induced by past climatic cycles compounded by human-induced population declines. Genome-wide scans of selection showed that disparate limb proportions in the bush dog and maned wolf may derive from mutations in genes regulating chondrocyte proliferation and enlargement. Further, frugivory in the maned wolf may have been enabled by variants in genes associated with energy intake from short-chain fatty acids. In contrast, unique genetic variants detected in the bush dog may underlie interdigital webbing and dental adaptations for hypercarnivory. Our analyses shed light on the evolution of a unique carnivoran radiation and how it was shaped by South American topography and climate change. [ABSTRACT FROM AUTHOR]

Published
2022
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34. Complex Evolutionary History of the South American Fox Genus Lycalopex (Mammalia, Carnivora, Canidae) Inferred from Multiple Mitochondrial and Nuclear Markers.

Author

Favarini, Marina O., Simão, Taiz L. L., Macedo, Gabriel S., Garcez, Fabrício S., Oliveira, Larissa R., Cárdenas-Alayza, Susana, Cardeña Mormontoy, Marco, Angulo, Fernando, Kasper, Carlos Benhur, Johnson, Warren E., and Eizirik, Eduardo

Subjects
CANIDAE, UNITED States history, MITOCHONDRIA, MAMMALS, MITOCHONDRIAL DNA, CARNIVORA, SPECIES hybridization
Abstract

The canid genus Lycalopex comprises six recently diversified South American species whose evolutionary relationships have been remarkably challenging to resolve. We analyzed 6000 bp of mitochondrial DNA (mtDNA) from 55 Lycalopex individuals (L. sechurae = 4, L. culpaeus = 7, L.griseus = 8, L.gymnocercus = 17, L.vetulus = 13 and L. fulvipes = 6), and nine specimens from the closely related species Cerdocyon thous, Chrysocyon brachyurus and Speothos venaticus, to reconstruct their phylogenetic relationships, estimate the support for species-level monophyly, and date their divergences. In addition, we also sequenced seven nuclear segments from the same taxa. Three different phylogenetic approaches converged on the same mitochondrial topology with strong support for most nodes. All species were confirmed to be monophyletic for mtDNA, except for one intriguing case in which two L. vetulus individuals carried L. gymnocercus haplotypes, potentially implying a case of interspecies admixture. L. vetulus was the first species to diverge (ca. 1.2 Mya), followed by L. sechurae and then L. gymnocercus. The most internal group comprised L. griseus and the sister-species L. culpaeus and L. fulvipes, which diverged around 430,000 years ago in southern Argentina or Chile. The analysis of nuclear markers revealed several examples of intra-specific variation coupled with lack of species monophyly, consistent with pervasive incomplete lineage sorting and/or hybridization in this recent radiation. Our results provide robust mitochondrial resolution of this challenging radiation, and illustrate the difficulty of attaining similar success with traditional nuclear markers. [ABSTRACT FROM AUTHOR]

Published
2022
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35. RESEARCH ARTICLE: Comparative genomics reveals insights into avian genome evolution and adaptation

Author

Zhang, Guojie, Li, Cai, Li, Qiye, Li, Bo, Larkin, Denis M., Lee, Chul, Storz, Jay F., Antunes, Agostinho, Greenwold, Matthew J., Meredith, Robert W., Ödeen, Anders, Cui, Jie, Zhou, Qi, Xu, Luohao, Pan, Hailin, Wang, Zongji, Jin, Lijun, Zhang, Pei, Hu, Haofu, Yang, Wei, Hu, Jiang, Xiao, Jin, Yang, Zhikai, Liu, Yang, Xie, Qiaolin, Yu, Hao, Lian, Jinmin, Wen, Ping, Zhang, Fang, Li, Hui, Zeng, Yongli, Xiong, Zijun, Liu, Shiping, Zhou, Long, Huang, Zhiyong, An, Na, Wang, Jie, Zheng, Qiumei, Xiong, Yingqi, Wang, Guangbiao, Wang, Bo, Wang, Jingjing, Fan, Yu, da Fonseca, Rute R., Alfaro-Núñez, Alonzo, Schubert, Mikkel, Orlando, Ludovic, Mourier, Tobias, Howard, Jason T., Ganapathy, Ganeshkumar, Pfenning, Andreas, Whitney, Osceola, Rivas, Miriam V., Hara, Erina, Smith, Julia, Farré, Marta, Narayan, Jitendra, Slavov, Gancho, Romanov, Michael N, Borges, Rui, Machado, João Paulo, Khan, Imran, Springer, Mark S., Gatesy, John, Hoffmann, Federico G., Opazo, Juan C., Håstad, Olle, Sawyer, Roger H., Kim, Heebal, Kim, Kyu-Won, Kim, Hyeon Jeong, Cho, Seoae, Li, Ning, Huang, Yinhua, Bruford, Michael W., Zhan, Xiangjiang, Dixon, Andrew, Bertelsen, Mads F., Derryberry, Elizabeth, Warren, Wesley, Wilson, Richard K, Li, Shengbin, Ray, David A., Green, Richard E., OʼBrien, Stephen J., Griffin, Darren, Johnson, Warren E., Haussler, David, Ryder, Oliver A., Willerslev, Eske, Graves, Gary R., Alström, Per, Fjeldså, Jon, Mindell, David P., Edwards, Scott V., Braun, Edward L., Rahbek, Carsten, Burt, David W., Houde, Peter, Zhang, Yong, Yang, Huanming, Wang, Jian, Consortium, Avian Genome, Jarvis, Erich D., Gilbert, M. Thomas P., and Wang, Jun

Published
2014
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41. Genomic Signatures of Divergent Ecological Strategies in a Recent Radiation of Neotropical Wild Cats.

Author

Ramirez, Jorge L., Lescroart, Jonas, Figueiró, Henrique V., Torres-Florez, Juan Pablo, Villela, Priscilla M. S., Coutinho, Luiz L., Freitas, Patricia D., Johnson, Warren E., Antunes, Agostinho, Galetti, Pedro M., and Eizirik, Eduardo

Subjects
FELIDAE, WHOLE genome sequencing, MOLECULAR phylogeny, RADIATION, COMPARATIVE historiography, EYE color
Abstract

Ecological differentiation among diverging species is an important component of the evolutionary process and can be investigated in rapid and recent radiations. Here, we use whole genome sequences of five species from the genus Leopardus , a recently diversified Neotropical lineage with species bearing distinctive morphological, ecological, and behavioral features, to investigate genome-wide diversity, comparative demographic history and signatures of positive selection. Our results show that divergent ecological strategies are reflected in genomic features, for example a generalist species shows historically larger effective population size and higher heterozygosity than habitat specialists. The demographic history of these cats seems to have been jointly driven by climate fluctuations and habitat specialization, with different ecological adaptations leading to distinct trajectories. Finally, a gene involved in vertebrate retinal neurogenesis (POU4F2) was found to be under positive selection in the margay, a cat with notoriously large eyes that are likely associated with its nocturnal and arboreal specializations. [ABSTRACT FROM AUTHOR]

Published
2022
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42. Genetic characterization of feline leukemia virus from Florida panthers

Author

Brown, Meredith A., Cunningham, Mark W., Roca, Alfred L., Troyer, Jennifer L., Johnson, Warren E., and O'Brien, Stephen J.

Subjects
Feline leukemia virus -- Identification and classification, Feline leukemia virus -- Health aspects, Feline leukemia virus -- Genetic aspects, Feline leukemia virus -- Distribution, Feline leukemia virus -- Research, Panthers -- Health aspects, Panthers -- Genetic aspects, Panthers -- Research
Abstract

From 2002 through 2005, an outbreak of feline leukemia virus (FeLV) occurred in Florida panthers (Puma concolor coryi). Clinical signs included lymphadenopathy, anemia, septicemia, and weight loss; 5 panthers died. [...]

Published
2008

43. The evolution of cats

Author

O'Brien, Stephen J. and Johnson, Warren E.

Subjects
Felidae -- Natural history, Felidae -- Genetic aspects, Cats -- Natural history, Cats -- Genetic aspects
Published
2007

47. Molecular phylogenetics and the origins of placental mammals

Author

Murphy, William J., Eizirik, Eduardo, Johnson, Warren E., Zhang, Ya Ping, Ryder, Oliver A., and O'Brien, Stephen J.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): William J. Murphy [1, 2]; Eduardo Eizirik [1, 3, 2]; Warren E. Johnson [1]; Ya Ping Zhang [4]; Oliver A. Ryder [5]; Stephen J. O'Brien (corresponding author) [1] The [...]

Published
2001
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