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We report the discovery of the quadruply lensed quasar SDSS J1433+6007 (RA =14:33:22.8, Dec.=+60:07:13.44), mined in the SDSS DR12 photometric catalogues using a novel outlierselection technique, without prior spectroscopic or ultraviolet excess information. Discovery data obtained at the Nordic Optical Telescope (La Palma) show nearly identical quasar spectra at zs = 2.737 ± 0.003 and four quasar images in a fold configuration, one of which sits on a blue arc, with maximum separation 3.6 arcsec. The deflector redshift is zl = 0.407 ± 0.002, from Keck-ESI spectra. We describe the selection procedure, discovery and follow-up, image positions and BVRi magnitudes, and first results and forecasts from lens model fit to the relative image positions. [ABSTRACT FROM AUTHOR]

We present a tomographic analysis of metal absorption lines arising from the circumgalactic medium (CGM) of galaxies at z ≈ 0.5–2, using Multi Unit Spectroscopic Explorer (MUSE) observations of two background quasars at z ≈ 2.2 and 2.8, which are two of the few currently known quasars with multiple images due to strong gravitational lensing by galaxy clusters at z ≈ 0.6 and 0.5, respectively. The angular separations between different pairs of quasar multiple images enable us to probe the absorption over transverse physical separations of ≈0.4–150 kpc, which are based on strong lensing models exploiting MUSE observations. The fractional difference in rest-frame equivalent width (Δ W r) of Mg  ii , Fe  ii , and C  iv absorption increases on average with physical separation, indicating that the metal-enriched gaseous structures become less coherent with distance, with a likely coherence length-scale of ≈10 kpc. However, Δ W r for all the ions vary considerably over ≈0.08–0.9, indicating a clumpy CGM over the full range of length-scales probed. At the same time, paired Mg  ii absorption is detected across ≈100–150 kpc at similar line-of-sight velocities, which could be probing cool gas clouds within the same halo. No significant dependence of Δ W r is found on the equivalent width and redshift of the absorbing gas and on the galaxy environment associated with the absorption. The high-ionization gas phase traced by C  iv shows a higher degree of coherence than the low-ionization gas phase traced by Mg  ii , with ≈90 per cent of C  iv systems exhibiting Δ W r ≤ 0.5 at separations ≤10 kpc compared to ≈50 per cent of Mg  ii systems. [ABSTRACT FROM AUTHOR]

The detection of the accelerated expansion of the Universe has been one of the major breakthroughs in modern cosmology. Several cosmological probes (Cosmic Microwave Background, Supernovae Type Ia, Baryon Acoustic Oscillations) have been studied in depth to better understand the nature of the mechanism driving this acceleration, and they are being currently pushed to their limits, obtaining remarkable constraints that allowed us to shape the standard cosmological model. In parallel to that, however, the percent precision achieved has recently revealed apparent tensions between measurements obtained from different methods. These are either indicating some unaccounted systematic effects, or are pointing toward new physics. Following the development of CMB, SNe, and BAO cosmology, it is critical to extend our selection of cosmological probes. Novel probes can be exploited to validate results, control or mitigate systematic effects, and, most importantly, to increase the accuracy and robustness of our results. This review is meant to provide a state-of-art benchmark of the latest advances in emerging "beyond-standard" cosmological probes. We present how several different methods can become a key resource for observational cosmology. In particular, we review cosmic chronometers, quasars, gamma-ray bursts, standard sirens, lensing time-delay with galaxies and clusters, cosmic voids, neutral hydrogen intensity mapping, surface brightness fluctuations, stellar ages of the oldest objects, secular redshift drift, and clustering of standard candles. The review describes the method, systematics, and results of each probe in a homogeneous way, giving the reader a clear picture of the available innovative methods that have been introduced in recent years and how to apply them. The review also discusses the potential synergies and complementarities between the various probes, exploring how they will contribute to the future of modern cosmology. [ABSTRACT FROM AUTHOR]

Cold dark matter (CDM) constitutes most of the matter in the Universe. The interplay between dark and luminous matter in dense cosmic environments, such as galaxy clusters, is studied theoretically using cosmological simulations. Observations of gravitational lensing are used to characterize the properties of substructures—the small-scale distribution of dark matter—in clusters. We derive a metric, the probability of strong lensing events produced by dark-matter substructure, and compute it for 11 galaxy clusters. The observed cluster substructures are more efficient lenses than predicted by CDM simulations, by more than an order of magnitude. We suggest that systematic issues with simulations or incorrect assumptions about the properties of dark matter could explain our results. [ABSTRACT FROM AUTHOR]

We analyse the Kormendy relations (KRs) of the two Frontier Fields clusters, Abell S1063, at z = 0.348, and MACS J1149.5+2223, at z = 0.542, exploiting very deep Hubble Space Telescope photometry and Very Large Telescope (VLT)/Multi Unit Spectroscopic Explorer (MUSE) integral field spectroscopy. With this novel data set, we are able to investigate how the KR parameters depend on the cluster galaxy sample selection and how this affects studies of galaxy evolution based on the KR. We define and compare four different galaxy samples according to (a) Sérsic indices: early-type ('ETG'), (b) visual inspection: 'ellipticals', (c) colours: 'red', (d) spectral properties: 'passive'. The classification is performed for a complete sample of galaxies with mF814W = 22.5 ABmag (M* ≳ 1010.0 M☉). To derive robust galaxy structural parameters, we use two methods: (1) an iterative estimate of structural parameters using images of increasing size, in order to deal with closely separated galaxies and (2) different background estimations, to deal with the intracluster light contamination. The comparison between the KRs obtained from the different samples suggests that the sample selection could affect the estimate of the best-fittingKR parameters. TheKR built with ETGs is fully consistent with the one obtained for ellipticals and passive. On the other hand, the KR slope built on the red sample is only marginally consistent with those obtained with the other samples. We also release the photometric catalogue with structural parameters for the galaxies included in the present analysis. [ABSTRACT FROM AUTHOR]

ABSTRACT Strong gravitational lensing magnifies the flux from distant galaxies, allowing us to detect emission lines that would otherwise fall below the detection threshold for medium-resolution spectroscopy. Here we present the detection of temperature-sensitive oxygen emission lines from three galaxies at 2 ≲ z ≲ 3.5, which enables us to directly determine the oxygen abundances and thereby double the number of galaxies at z > 2 for which this has been possible. The three galaxies have ∼10 per cent solar oxygen abundances in agreement with strong emission-line diagnostics. Carbon and nitrogen ratios relative to oxygen are subsolar as expected for young metal-poor galaxies. Two of the galaxies are Lyman α (Lyα) emitters with rest-frame equivalent widths of 20 and 40 Å, respectively, and their high magnification factors allow us for the first time to gain insight into the physical characteristics of high-redshift Lyα emitters. Using constraints from the physical properties of the galaxies, we accurately reproduce their line profiles with radiative transfer models. The models show a relatively small outflow in agreement with the observed small velocity offsets between nebular emission and interstellar absorption lines. [ABSTRACT FROM AUTHOR]

ABSTRACT We present Very Large Telescope/X-shooter spectra of 13 galaxies in the redshift range 1 ≲ z ≲ 6, which are strongly lensed by massive galaxy clusters. Spectroscopic redshifts are measured for nine galaxies, while three sources have redshifts determined from continuum breaks in their spectra. The stellar masses of the galaxies span four orders of magnitude between 107 and 1011 M⊙ and have luminosities at 1500 Å rest frame between 0.004 and 9 L* after correcting for the magnification. This allows us to probe a variety of galaxy types from young, low-mass starburst galaxies to massive evolved galaxies. The lensed galaxies with stellar masses less than 1010 M⊙ have a large scatter compared to the fundamental relation between stellar mass, star formation rates and oxygen abundances. We provide a modified fit to the fundamental relation for low-mass, low-metallicity galaxies with a weaker dependence of the metallicity on either the star formation rate or stellar mass compared to low-redshift, high-mass and high-metallicity Sloan Digital Sky Survey galaxies. [ABSTRACT FROM AUTHOR]

ABSTRACT We show the effectiveness of strong lensing in the characterization of Lyman continuum emission from faint L≲ 0.1 L* star-forming galaxies at redshift ≳3. Past observations of L≳ L* galaxies at redshift ≳3 have provided upper limits of the average escape fraction of ionizing radiation of fesc∼ 5 per cent. Galaxies with relatively high fesc (>10 per cent) seem to be particularly rare at these luminosities; there is therefore the need to explore fainter limits. Before the advent of giant ground-based telescopes, one viable way to probe fesc down to 0.05-0.15 L* was to exploit strong lensing magnification. This is investigated with Monte Carlo simulations that take into account the current observational capabilities. Adopting a lensing cross-section of 10 arcmin2 within which the magnification is higher than 1 (achievable with about four to five galaxy clusters), with a U-band survey depth of 30 (30.5) ( AB, 1σ), it is possible to constrain fesc for z≃ 3 star-forming galaxies down to 15 (10) per cent at 3σ for L < 0.15 L* luminosities. This is particularly interesting if fesc increases at fainter luminosities, as predicted from various H i reionization scenarios and radiation transfer modelling. Ongoing observational programmes on galaxy clusters are discussed and positive prospects for the future are offered, even though from space the Hubble Space Telescope ( HST)/Wide Field Camera 3 (WFC3) instrument represents the only option we have to investigate details of the spatial distribution of the Lyman continuum emission arising from z∼ 2-4 galaxies. [ABSTRACT FROM AUTHOR]

Abstract: A cytolytic assay that could detect palytoxin and its congeners has been developed by the use of an established cell line grown as monolayer to replace the current hemolytic method. We used MCF-7 cells and cytolysis was measured by the release of cytosolic lactate dehydrogenase (LDH) in the buffer added to treated cells (culture supernatant). A dose-dependent increase in LDH activity in culture supernatants was detected when MCF-7 cells were exposed to palytoxin and its analogue ostreocin D. The cytolytic response induced by palytoxin and ostreocin D was specific for this group of compounds, acting on Na+/K+-ATPase, as it was prevented when cells were preincubated with ouabain. The specificity of our assay for palytoxin and its congeners was confirmed by the finding that cytolysis was not detected when MCF-7 cells were exposed to unrelated toxins such as maitotoxin, tetrodotoxin, okadaic acid, and yessotoxin, even in the case of compounds that elicit cytotoxic responses under our experimental conditions. Using extracts from biological materials after spiking with the palytoxin standard, we found a good correlation between palytoxin levels measured by our cytolytic assay and the expected values. Our cytolytic assay detected palytoxin in naturally contaminated materials, but estimates were significantly higher than the palytoxin contents determined by LC–MS, indicating that naturally contaminated materials contain biologically active palytoxin congeners. We conclude that our cytolytic assay based on the use of MCF-7 cell monolayers is a viable alternative to animal-based methods for the determination of palytoxin and its congeners in contaminated materials. [Copyright &y& Elsevier]

In this article we report on the liquid chromatography tandem mass spectrometry (LC-MS) investigation of plankton samples collected in the summer of 2006 along the Ligurian coasts, coinciding with a massive bloom of the tropical microalga Ostreopsis ovata. LC-MS analyses indicated the occurrence of putative palytoxin along with a much more abundant palytoxin-like compound never reported so far, which we named ovatoxin-a. On the basis of molecular formula, fragmentation pattern, and chromatographic behavior, the structure of ovatoxin-a appeared to be strictly related to that of palytoxin. We report also on the analysis of cultured O. ovata, which was necessary to unequivocally demonstrate that putative palytoxin and ovatoxin-a contained in field samples were actually produced by O. ovata itself. [Copyright &y& Elsevier]

A new method for sensitive, specific, and direct determination of palytoxin is proposed herein. It is based on combination of reversed-phase liquid chromatography with mass spectrometry (LC-MS). The new method was set up on a turbo ion spray-triple quadrupole MS instrument operating in selected ion monitoring (SIM) and multiple reaction monitoring (MRM) acquisition modes (positive ions). The minimum detection levels for matrix-free toxin on column were thus estimated from the data to be 200 and 125 pg in SIM and MRM modes, respectively. Spiking experiments before and after extraction allowed us to assess limits of detection and quantitation for palytoxin in matrix, accuracy, and intraday and inter-day reproducibility of the method. The developed method was decisive for the analysis of a plankton sample collected along Genoa coasts in July 2005 when respiratory illness in people exposed to marine aerosols occurred. It is suggested that putative palytoxin was the causative agent responsible for patients' symptoms and demonstrated for the first time the presence of such a toxin in Italian waters. [ABSTRACT FROM AUTHOR]