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In this paper, the collapse of a void bubble filled with vapor content is numerically investigated using a novel moving particle semi-implicit with meshless advection by flow-directional local grid (MPS-MAFL) method. The interfacial velocity, collapse time, bubble shape variation, peak pressure, rebound bubble radius, and other interesting parameters were obtained and are discussed profoundly. The vapor bubble undergoes several cycles of oscillation with reduced amplitude during the whole collapse process, which is similar to cavitation bubble collapse. The computational results show that the bubble collapse time is linearly proportional to the initial bubble size, which agrees with the Rayleigh equation. The minimum rebound bubble radius ratio is less affected by initial bubble size for a large bubble. Comparison work was also conducted against experimental data by Board and Kimpton. The comparison revealed that the MPS method supplied with an adiabatic compression assumption for vapor content is more suitable to evaluate the collapse behaviors of a low-pressure vapor bubble. This work is helpful for further application of the moving particle semi-implicit with meshless advection using flow-directional local grid (MPS-MAFL) method to solving complicated bubble dynamics. [ABSTRACT FROM AUTHOR]