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Lateral variations of shear wave velocity (V S) profile and time-averaged shear wave velocity in the upper 30 m (V S 30) are important indicators of site condition and significant contributors to uncertainty in earthquake ground motion and seismic hazards. Few previous studies involved in quantifying these lateral variations, especially at short distances, due to limited data at closely spaced sites. This study quantitatively investigated the lateral variation of V S profile and V S 30 over plain and piedmont terrains, focusing on short distances ranging from hundreds of meters to several kilometers. 2510 plain and 749 piedmont borehole profiles from the mainland China borehole profile database were employed to examine these variations using the variogram as the geo-statistics tool. The main findings include: 1) Over plain terrain, the variation in site conditions between sites does not significantly increase with separation distance within a certain range (typically from 1 km to 3–5 km). Over piedmont terrain, site condition variation steadily increases with distance. 2) The variation of site condition over piedmont terrain is higher than that over plain terrain. Nonetheless, for both terrains, the dispersion of site condition between sites at distance of <1 km is engineering negligible, and the correlation of site conditions between sites within 5 km remains strong; 3) For both terrains, the lateral variation of V S in deeper layers is higher than that in shallower layers. The study outcomes emphasize the importance of incorporating the information of nearby measurements in site condition estimations. The study outcomes can also be utilized in the optimization of borehole sampling design for microzonation projects and the evaluation of site condition dispersion at inferred sites. • Lateral variations of V S profile & V S 30 over plain & piedmont terrains were modeled. • The study focuses on lateral variations at short distance, down to < 1 km scale. • For gentle terrains, site conditions within short distance are strong correlated. • Plain has lower site condition variation than piedmont, with distinct properties. [ABSTRACT FROM AUTHOR]