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Digital twins (DTs) are becoming increasingly popular in various industries, and their potential for healthcare in the metaverse continues to attract attention. The metaverse is a virtual world where individuals interact with digital replicas of themselves and the environment. This paper focuses on personalized and precise medicine and examines the current application of DTs in healthcare within the metaverse. Healthcare practitioners may use immersive virtual worlds to replicate medical scenarios, improve teaching experiences, and provide personalized care to patients. However, the integration of DTs in the metaverse poses technical, regulatory, and ethical challenges that need to be addressed, including data privacy, standards, and accessibility. Through this examination, we aim to provide insights into the transformative potential of DTs in healthcare within the metaverse and encourage further research and development in this exciting domain. [ABSTRACT FROM AUTHOR]

Digital twin is the digital representation of an entity, and it drives Industry 4.0. This paper presents a bibliometric analysis of digital twin in the supply chain to help researchers, industry practitioners, and academics to understand the trend, development, and focus of the areas of digital twin in the supply chain. This paper found several key clusters of research, including the designing of a digital twin model, integration of a digital twin model, application of digital twin in quality control, and digital twin in digitalization. In the embryonic stage of research, digital twin was tested in the production line with limited optimization. In the development stage, the importance of digital twin in Industry 4.0 was observed, as big data, machine learning, Industrial Internet of Things, blockchain, edge computing, and cloud-based systems complemented digital twin models. Digital twin was applied to improve sustainability in manufacturing and production logistics. In the current prosperity stage with high annual publications, the recent trends of this topic focus on the integration of deep learning, data models, and artificial intelligence for digitalization. This bibliometric analysis also found that the COVID-19 pandemic drove the start of the prosperity stage of digital twin research in the supply chain. Researchers in this field are slowly moving towards applying digital twin for human-centric systems and mass personalization to prepare to transit to Industry 5.0. [ABSTRACT FROM AUTHOR]

Preparing the infrastructure for analyzing, recognizing, and characterizing microorganisms in the Metaverse can transform the fields of biology, medicine, and drug discovery. Accordingly, the realization of digital twins of microorganisms, such as viruses, fungi, algae, bacteria, protozoa, archaea, and multicellular animal parasites, can streamline the applicability of the Metaverse and similar emerging technologies like Cyber-Physical Healthcare Systems (CPHS). This is why a new approach to the digital twinning of bacteria has been presented in this research. This method of digital twinning can revolutionize the research and study of bacteria because it allows us to separate useful and harmful bacterial species, increasing the efficiency of treatment noticeably. This innovative method can easily be used by clinics, medical centers, or even by private users physically and virtually and can be adapted to every centralized or decentralized Metaverse Platform. To determine the proper treatment, biologists have always tried to identify the correct bacterial species that prompted a bacterial infection. They use various indicators, such as the bacterial cell's shape and the size of the colony formed by the bacteria, to classify different types of bacteria with different biochemistries and shapes. However, it is challenging because of the extensive similarities between some species. For instance, such similarities exist between Staphylococcus aureus and Staphylococcus saprophyticus, which has caused numerous false diagnostic reports by operators. Wrong species reports bring about treatment failure and increase antibiotic resistance issues. Therefore, the digital twins of bacteria cover all of their identifiable characteristics and overcome many limitations to study them. In this approach, DTL techniques, including MobileNetV2, EfficientNetV2-S, and ResNet-50, have been employed to build digital twins of bacteria species. A hybrid dataset was used for training and evaluation. Among the models, EfficientNetV2-S exhibited the best performance, with a validation accuracy of 99.58% and a test accuracy of 99.33%. The results showed the ability of deep learning models to make bacteria digital twins based on image processing from different labs, thus assisting experts in speeding up the process and reducing diagnostic errors. In addition, in the mispredicted cases, the correct species was among the first three choices of the model. Therefore, not only can experts use DTL approaches to speed up the digital twin realization of microorganisms in the Metaverse, but they can also use these methods to reduce diagnostic errors. • Introducing a technique to streamline digital twinning of microorganisms using CNN. • Describing machine learning digital twins of microorganisms in the Metaverse. • Presenting an exact, economical digital twinning approach via smartphone photography. • Providing a comprehensive bacteria species dataset for future method development. [ABSTRACT FROM AUTHOR]

Digital twins are undergoing growth that enables highly informative and scaleable interaction between physical objects and virtual twins, which is of great significance to the life cycle analysis of composites. Real-time fine evolution is challenging due to vast combinations of input features and high-resolution calculated variables. Here, we systematically demonstrate an AI-based methodology for digital twinning of complex composite structures. First, three types of deep neural networks are created with optionally used autoencoders as surrogate models, with architectures and data processing inspired by the rule-of-mixture of composites. Second, the prediction accuracy and efficiency are evaluated quantitatively and qualitatively, demonstrating the feasibility of predicting 3D displacement and stress fields directly from sensing data of temperature, pressure and loading displacement, and the optimal architecture is selected to be the evolving digital twin. Finally, the real-time interactive experiments are relayed to the digital twin and demonstrated that it can interact with physical objects and evolve online with high accuracy. These results indicate that the computational time can be reduced by 3∼6 orders of magnitude with high information intensity and scalability compared with conventional numerical and experimental methods, which opens up the avenues for the cost-effective and efficient development of digital twin services for composites. [Display omitted] [ABSTRACT FROM AUTHOR]

• Key application areas of deep learning are identified in urban water and wastewater management. • Popular application areas include anomaly detection, system state forecasting, asset monitoring and assessment. • Industrial application of deep learning is still at an early stage with few implementations reported. • Research challenges include data privacy, algorithm development, explainability, multi-agent system and digital twin. • Deep learning should drive urban water systems towards high intelligence and autonomy. Deep learning techniques and algorithms are emerging as a disruptive technology with the potential to transform global economies, environments and societies. They have been applied to planning and management problems of urban water systems in general, however, there is lack of a systematic review of the current state of deep learning applications and an examination of potential directions where deep learning can contribute to solving urban water challenges. Here we provide such a review, covering water demand forecasting, leakage and contamination detection, sewer defect assessment, wastewater system state prediction, asset monitoring and urban flooding. We find that the application of deep learning techniques is still at an early stage as most studies used benchmark networks, synthetic data, laboratory or pilot systems to test the performance of deep learning methods with no practical adoption reported. Leakage detection is perhaps at the forefront of receiving practical implementation into day-to-day operation and management of urban water systems, compared with other problems reviewed. Five research challenges, i.e., data privacy, algorithmic development, explainability and trustworthiness, multi-agent systems and digital twins, are identified as key areas to advance the application and implementation of deep learning in urban water management. Future research and application of deep learning systems are expected to drive urban water systems towards high intelligence and autonomy. We hope this review will inspire research and development that can harness the power of deep learning to help achieve sustainable water management and digitalise the water sector across the world. [Display omitted] [ABSTRACT FROM AUTHOR]