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With the aging of the global workforce, it is crucial to deepen our understanding of how to keep older workers healthy, motivated, and productive. In this research, we integrate job design with socioemotional selectivity theory to propose that social job characteristics relate to employee performance differently for older and younger workers. Specifically, in a 3-wave survey (N = 454), we tested employee age as a moderator of the relationships between receiving social support and feedback at work, and performance, as well as giving social support and feedback at work, and performance. The results showed that, in general, both receiving and giving social support and feedback are associated more strongly with the performance of older than younger workers. The findings provide important theoretical implications for the study of aging and work; they also offer practical applications for creating workplaces in which older workers can reap the benefits of social relationships to remain productive. [ABSTRACT FROM AUTHOR]

Patient journey mapping is an emerging field of research that uses various methods to map and report evidence relating to patient experiences and interactions with healthcare providers, services, and systems. This research often involves the development of visual, narrative, and descriptive maps or tables, which describe patient journeys and transitions into, through, and out of health services. This methods corner paper presents an overview of how patient journey mapping has been conducted within the health sector, providing cardiovascular examples. It introduces six key steps for conducting patient journey mapping and describes the opportunities and benefits of using patient journey mapping and future implications of using this approach. [ABSTRACT FROM AUTHOR]

Group projects are part of the core educational experience in higher education, but many students report bad experiences with them, characterized by negative emotions and group problems. Group problems may undermine learning and cause stress and frustration. This may be prevented by monitoring and supporting groups, but this is often not feasible for teachers, who lack time and resources. This research aims to find a method for early identification of group work problems via computer-supported assessment. First, interviews and focus groups provided insights into the most common group problems and which visual features students preferred in a peer assessment. Next, two assessment versions were created: a simple, time-efficient version, and a more engaging, interactive one. We also created an initial version of E-Mate, a virtual agent that provides feedback on the assessment. These were tested in a field study. Most students reported a positive experience with the peer assessment, regardless of the version used. Teachers were also positive about its usefulness. Based on the feedback received, new features were added to the peer assessment survey and the E-Mate was redesigned; this new version was tested in a second field study. The results are in line with the previous field study and confirm the positive reception and usefulness of the survey, supporting the use of five attributes to evaluate group collaboration and the usage of a peer assessment survey to assess group work. [ABSTRACT FROM AUTHOR]

We conduct a discrete choice experiment to investigate how the location of a firm in a rural or urban region affects the perceived job attractiveness for university students and graduates and, therewith, contributes to the rural–urban divide. We characterize the attractiveness of a location based on several dimensions (social life, public infrastructure and connectivity) and vary job design and contractual characteristics of the job. We find that job offers from companies in rural areas are generally considered less attractive, regardless of the attractiveness of the region. The negative perception is particularly pronounced among persons of urban origin and singles. In contrast, for individuals with partners and kids this preference is less pronounced. High-skilled individuals who originate from rural areas have no specific regional preference at all. [ABSTRACT FROM AUTHOR]

Research on the effectiveness of age-friendly organizational practices tends to focus on older employees' perceptions of these. Drawing on perceptual congruence and psychological contract theory, we hypothesize that leaders' perceptions of these organizational practices are relevant as well. Specifically, we argue that (dis)agreement between leaders' and older employees' perceptions (i.e. perceptual (in)congruence) of organizational practices related to age-friendly organizational climate, management, and work design plays a role in older employees' well-being. Polynomial regression and response surface analysis were applied to a dyadic sample of 484 older employees and their leaders from 100 diverse organizations. Results reveal that leader-employee perceptual congruence on high levels of perceived age-friendly work design was related to higher employee well-being. By contrast, older employees' well-being was lower when leaders evaluated the three age-friendly organizational practices higher than their older employees. Our findings suggest that further theoretical consideration of the role of leader-employee perceptual (in)congruence for aging workforces is needed, and that scholars and organizations should acknowledge the relevance and interplay of different stakeholders' perceptions within an organization. [ABSTRACT FROM AUTHOR]

Older adults' smartphone use has been shown to be a double-edged sword, linked to health and social benefits but also creating vulnerabilities. Similarly, the use of smartphones and other information and communication technologies (ICTs) in organizations also affords workers advantages, such as increased flexibility, while exposing them to risks such as exhaustion and distress. This research examines older workers' smartphone use and identifies a contextual characteristic that may buffer the negative implications of smartphone use for work purposes. Following the job demands–resources (JD-R) model, we hypothesized that older workers' daily work-related smartphone use is positively related to their experienced stress and negatively related to their mood, and that these relationships would be attenuated by work scheduling autonomy. We conducted an experience sampling method (ESM) study with a sample of 38 workers (ages 50–64) who completed daily measures over 8 days, and tracked their smartphone use objectively using screenshots of time spent using various apps. Contrary to our expectations, smartphone use was not significantly related to stress or mood. There were significant cross-level interactions, such that smartphone use for work was negatively related to experienced stress and positively related to a positive mood for those with lower levels of scheduling autonomy. We interpret these findings and discuss the effects that technology use for work may have on older workers' well-being through the lens of the JD-R model. Our results suggest that ICT use in the workplace combined with work scheduling autonomy may not be advantageous for workers' well-being. [ABSTRACT FROM AUTHOR]

Work design plays an important role in workers' job-related well-being, but not every employee responds to work design in the same way. Given trends toward longer working lives and higher age diversity in the workforce, worker age is an important factor to consider. However, knowledge about the interplay between worker age and work design is limited, especially when considering the multitude of job characteristics that people experience at the same time. Integrating the work design and lifespan/career development literatures and adopting a person-centered approach, we investigated how worker age affects membership in work design profiles and the relationship between work design profiles and occupational well-being. Using two independent samples (N = 989; 980), we conducted latent profile analysis to group workers into work design profiles based on 6 age-relevant job characteristics (autonomy, information-processing, workload, social support, emotional demands, and social conflicts). We identified 3 profiles and linked them to well-being: motivating (most favorable), moderately stimulating, and socially taxing (least favorable). Older workers were more likely to be in, and responded better to motivating work design profiles, and less likely to be in, and responded worse to socially taxing profiles. Meanwhile, younger workers seemed more tolerant of socially taxing work design profiles than older workers. Most age-contingent effects were robust after adding organizational tenure as a covariate. Findings qualify lifespan development theories and shed light on workers' nuanced responses to work design profiles. [ABSTRACT FROM AUTHOR]

Formal job search has undergone massive transformations in the last two decades with the move to online platforms. This makes more stages of the job search process observable, and allows researchers to intervene in this market and improve the design of the job search process and the information available in it. This paper showcases studies that illustrate the potential of analyzing online job search data and of intervening in the online job search process. It presents the current insights and some open questions and highlights conditions under which some of the recent interventions are likely to improve market outcomes overall, rather than improving only the outcomes for the treated individuals. [ABSTRACT FROM AUTHOR]

Confocal X-ray fluorescence analysis is a non-destructive method that enables the determination of the elements depth distribution in the examined sample. Accurate determination of the elements depth distributions in various samples from measured depth profiles is very demanding, and generally, a valid procedure has not been developed as yet. The main aim of this work was to design and test a universal simplified calculation procedure, which would allow the calculation of the approximate shape of the depth profiles for a sample formed from layers of a given thickness and composition. To confirm the proposed calculation method, the standard reference material NIST 1412 was used, which is formed by a homogeneous multicomponent glass containing oxides of several measurable elements. This research compares the results of the measured and calculated depth profiles in the glass reference material, where the resulting depth curves correspond almost perfectly. [ABSTRACT FROM AUTHOR]

Wavelet decompositions of integral operators have proven their efficiency in reducing computing times for many problems, ranging from the simulation of waves or fluids to the resolution of inverse problems in imaging. Unfortunately, computing the decomposition is itself a hard problem which is oftentimes out of reach for large-scale problems. The objective of this work is to design fast decomposition algorithms based on another representation called product-convolution expansion. This decomposition can be evaluated efficiently, assuming that a few impulse responses of the operator are available, but it is usually less efficient than the wavelet decomposition when incorporated in iterative methods. The proposed decomposition algorithms, run in quasi-linear time and we provide some numerical experiments to assess its performance for an imaging problem involving space-varying blurs. [ABSTRACT FROM AUTHOR]

This article suggests that the illuminated initials and borderwork added to ten early printed books in England are attributable to a single illuminator, the 'Incunables Limner', an individual for whom there is circumstantial evidence that he specialized in the illumination of printed books. Five of these books are copies of William Caxton's Golden Legend (Westminster, 1483–84), while the other five are Continental imprints (two from Strasbourg, and one from each of Basel, Verona, and Parma) printed between 1476 and 1484. In addition, a second illuminator can be identified in a sixth copy of Caxton's Golden Legend , working to the same design as that employed within the five copies decorated by the Incunables Limner. The possibility is considered that books illuminated by the Incunables Limner were products of Caxton's overseas trade, and that it was through acting in this capacity that the artist's specialization was viable. The Continental books are explored for what they might imply about Caxton's wider book-selling strategies, and three with evidence for early English ownership are selected for particular attention. [ABSTRACT FROM AUTHOR]

The quality and shelf-life of NCS (non-centrifugal sugar) mainly depend on the moisture content present in it. NCS formed by the current practice of open sun drying contains moisture substantially greater than the acceptable level of 3%. This paper presents the work undertaken to design a tunnel dryer to achieve the required moisture content of granular NCS for various load conditions. An experimental investigation was conducted on a laboratory-scale dryer to achieve the required moisture content for various loads. This experimental data was compared with the output of two drying models and a validated one that could be used to design an industrial-scale dryer. For various load conditions on each tray and dryer exit temperature, nine different cases were determined. The number of trucks, drying time, and energy requirements were computed using the validated theoretical model. A tunnel dryer with a length, height and width of 18, 1.2 and 1 m respectively and 18 trucks with 24 trays on each truck is shown to be dry 1 tone of NCS based on the minimum energy requirement of 176.49 MJ, and a drying time of 68 min. [ABSTRACT FROM AUTHOR]

When the same person is described as a 'Capitalist Revolutionary' and a 'Bourgeois Marxist', you know that there is a tug of war going on between opposing ideologies to claim the ideas of that person: in this case, John Maynard Keynes. James Crotty, in his recent book, Keynes against Capitalism , joins the game. Crotty takes issue with the conventional interpretation: that Keynes was trying to save capitalism. Instead, he argues that from the mid-1920s until his death in 1946, Keynes consistently argued for replacing capitalism with 'liberal socialism'. Crotty also maintains that The General Theory was designed to provide the theoretical foundation in support of his case against capitalism, in favour of liberal socialism. We contend that these labels, however clear they might have been to Keynes, are now laden with all sorts of interpretive baggage, and that Keynes's thinking was rather too subtle and complex to be comfortably described by them. To make this case, we examine the social purpose that Keynes's theoretical and policy work was designed to achieve and the means by which he thought it could best be achieved, as his thinking developed in the context of the rapidly changing times through which he lived. [ABSTRACT FROM AUTHOR]

This commentary describes the creation of a microbiology-themed Monopoly™ gameboard assignment for studying microbial diversity. Students worked in groups to redesign the standard Monopoly™ playing tokens, currency, action cards, properties, and special spaces for any microbial-themed topic using a provided template. A postassignment anonymous survey found that the students enjoyed this assignment and the opportunity to share their knowledge in a unique and creative format. While this assignment is especially amenable to microbiology due the large diversity seen in the microbial world, it could easily be adapted to other topics such as genetics, chemistry, or even math, where categorical associations or patterns are prevalent. [ABSTRACT FROM AUTHOR]

Reversible data hiding (RDH) with contrast enhancement (RDH-CE) is a special type of RDH in improving the subjective visual perception by enhancing the image contrast during the process of data embedding. In RDH-CE, data hiding is achieved via pairwise histogram expansion, and the embedding rate can be increased by performing multiple cycles of histogram expansions. However, when embedding rate gets high, human visible image degradation is observed. Previous work designed an upper bound of the embedding level for RDH-CE, which effectively avoids image over-sharping but offers limited embedding capacity. In this paper, a better tunable bound is designed to enhance the embedding capacity of RDH-CE by exploiting the characteristics of histogram distribution. Furthermore, the objective distortion introduced by histogram pre-shifting is minimized when the embedding level is no more than the upper bound, and the human visible degradation is minimized when the embedding level exceeds the limitation of the proposed upper bound. Experimental results validate that the proposed method provides appropriate upper bound of the embedding level, increases the effective embedding capacity and offers better image contrast. [ABSTRACT FROM AUTHOR]

Local air pollution has led authorities in many cities around the world to impose limits on car use by means of driving restrictions or license-plate bans. By placing uniform restrictions on all cars, many of these programs have created incentives for drivers to buy additional, more polluting cars. We study vintage-specific restrictions, which place heavy limits on older, polluting vehicles and no limits on newer, cleaner ones. We use a novel model of the car market and results from Santiago's 1992 program, the earliest program to use vintage-specific restrictions, to show that such restrictions should be designed to work exclusively through the extensive margin (type of car driven), never through the intensive margin (number of miles driven). If so, vintage restrictions can yield important welfare gains by moving the fleet composition toward cleaner cars, comparing well to alternative instruments such as scrappage subsidies and pollution-based registration fees. [ABSTRACT FROM AUTHOR]

In this article, we explore how classical organization theory can contribute to better comprehend the phenomenon "organizational networks." We will demonstrate that this juxtaposition can produce new and interesting insights. First, we argue that an organizational network can be understood as an organization following the classical definition by March and Simon. Second, we assume that organizational networks, as any other form of organizing, need to find solutions to four universal problems as suggested by Puranam and colleagues to be effective: task division, task allocation, reward provision, and information provision. Third, introducing and analyzing an existing organizational network for the management of housing expenses in a Dutch municipality helps us to reflect on how organizational networks in general and this network in particular have found solutions to the four problems of organizing. Finally, we present a number of interesting observations and implications resulting from the confrontation between organizational networks and organization theory and formulate a number of propositions to inspire and guide further research. [ABSTRACT FROM AUTHOR]

This paper examines the optimal compensation scheme, job design, and severance policy for a team using a model of repeated moral hazard. In the optimal contract, the agent may be paid to quit after a poor performance. We show that a generous severance policy facilitates the adoption of team incentives and team-based production by making it cost-effective to implement peer monitoring and sanction among the agents. [ABSTRACT FROM AUTHOR]

Background Few data exist to guide the physical design of biocontainment units, particularly the doffing area. This can impact the contamination risk of healthcare workers (HCWs) during doffing of personal protective equipment (PPE). Methods In phase I of our study, we analyzed simulations of a standard patient care task with 56 trained HCWs focusing on doffing of high-level PPE. In phase II, using a rapid cycle improvement approach, we tested different balance aids and redesigned doffing area layouts with 38 students. In phase III, we tested 1 redesigned layout with an additional 10 trained HCWs. We assessed the effectiveness of design changes on improving the HCW performance (measured by occurrence and number of risky behaviors) and reducing the physical and cognitive load by comparing the results from phase I and phase III. Results The physical load was highest when participants were removing their shoe covers without any balance aid; the use of a chair required the lowest physical effort, followed by horizontal and vertical grab bars. In the revised design (phase III), the overall performance of participants improved. There was a significant decrease in the number of HCW risky behaviors (P =.004); 5 risky behaviors were eliminated and 2 others increased. There was a significant decrease in physical load when removing disposable shoe covers (P =.04), and participants reported a similar workload in the redesigned doffing layout (P =.43). Conclusions Through optimizing the design and layout of the doffing space, we reduced risky behaviors of HCWs during doffing of high-level PPE. [ABSTRACT FROM AUTHOR]

Background: Few data exist to guide the physical design of biocontainment units, particularly the doffing area. This can impact the contamination risk of healthcare workers (HCWs) during doffing of personal protective equipment (PPE). Methods: In phase I of our study, we analyzed simulations of a standard patient care task with 56 trained HCWs focusing on doffing of high-level PPE. In phase II, using a rapid cycle improvement approach, we tested different balance aids and redesigned doffing area layouts with 38 students. In phase III, we tested 1 redesigned layout with an additional 10 trained HCWs. We assessed the effectiveness of design changes on improving the HCW performance (measured by occurrence and number of risky behaviors) and reducing the physical and cognitive load by comparing the results from phase I and phase III. Results: The physical load was highest when participants were removing their shoe covers without any balance aid; the use of a chair required the lowest physical effort, followed by horizontal and vertical grab bars. In the revised design (phase III), the overall performance of participants improved. There was a significant decrease in the number of HCW risky behaviors (P =.004); 5 risky behaviors were eliminated and 2 others increased. There was a significant decrease in physical load when removing disposable shoe covers (P =.04), and participants reported a similar workload in the redesigned doffing layout (P =.43). Conclusions: Through optimizing the design and layout of the doffing space, we reduced risky behaviors of HCWs during doffing of high-level PPE. The physical design of biocontainment units impacts the contamination risk of healthcare workers (HCWs) during doffing of personal protective equipment. Through optimizing the design and layout of the doffing space, HCWs perform fewer risky behaviors and are safer. [ABSTRACT FROM AUTHOR]

Motivation Accurate and wide-ranging prediction of thermodynamic parameters for biochemical reactions can facilitate deeper insights into the workings and the design of metabolic systems. Results Here, we introduce a machine learning method with chemical fingerprint-based features for the prediction of the Gibbs free energy of biochemical reactions. From a large pool of 2D fingerprint-based features, this method systematically selects a small number of relevant ones and uses them to construct a regularized linear model. Since a manual selection of 2D structure-based features can be a tedious and time-consuming task, requiring expert knowledge about the structure-activity relationship of chemical compounds, the systematic feature selection step in our method offers a convenient means to identify relevant 2D fingerprint-based features. By comparing our method with state-of-the-art linear regression-based methods for the standard Gibbs free energy prediction, we demonstrated that its prediction accuracy and prediction coverage are most favorable. Our results show direct evidence that a number of 2D fingerprints collectively provide useful information about the Gibbs free energy of biochemical reactions and that our systematic feature selection procedure provides a convenient way to identify them. Availability and implementation Our software is freely available for download at http://sfb.kaust.edu.sa/Pages/Software.aspx. Supplementary information Supplementary data are available at Bioinformatics online. [ABSTRACT FROM AUTHOR]

Background Falling retention in UK general practice is a well-described problem but there has been little previous research into its underlying causes. Poor psychosocial work conditions may help explain falling workforce morale and early retirement from the profession. Aims To explore the impact upon morale and retirement decisions of changes in psychosocial aspects of UK general practice over the course of a career. Methods Biographical narrative interviewing method (BNIM) was used to obtain and analyse career narratives of 12 London general practitioners (GPs), aged 55–65, half of whom had retired. Findings were theorized using the Job Demands-Control-Support (JDCS) model. Results A spontaneous, consistent theme was evident across all 12 interviews: changes in the psychosocial work environment had contributed to a steady decline in morale. Sequential, multilayered reductions in autonomy were the most commonly cited causes for reduced enthusiasm. Increasing demands in the form of both a rising workload as well as a complaints culture drained energy and morale. The GPs described increasingly fragmented teams and therefore reduced social support for the role. Nonetheless, retirement decisions were not straightforward, provoking complex emotions. Conclusions The combination of increasing demands with reduced autonomy puts practitioners under intense strain, diminishing the satisfaction they derive from their work and affecting retirement decisions. The Job Demands-Control-Support (JDCS) model is an empirically tested model that could be used to inform improved work design in general practice. [ABSTRACT FROM AUTHOR]

We develop and evaluate experimentally a novel tool that redesigns the job search process by providing tailored advice at low cost. We invited jobseekers to our computer facilities for twelve consecutive weekly sessions to search for real jobs on our web interface. For one-half, instead of relying on their own search criteria, we use readily available labour market data to display relevant alternative occupations and associated jobs. The data indicate that this broadens the set of jobs they consider and increases their job interviews especially for participants who otherwise search narrowly and have been unemployed for a few months. [ABSTRACT FROM AUTHOR]

Social scientists and management scholars have tended to see workplace interaction through the lens of hierarchy. However, modern workplaces include many people who do not fit neatly into such hierarchies because their work is designed to assess, support, sanction, or monitor other workers who already have well-established positions. Motivated by this observation, we conducted interviews with 193 infection preventionists—healthcare workers whose job it is to work with higher status physicians to monitor and suppress healthcare-acquired infections—to assess how workers outside of existing hierarchies can integrate their work. Inductive analyses of these interviews suggest three strategies: deference; relying on bureaucracy's routines and practices; and recruiting higher status confederates, which we call side-channeling. From these analyses, we introduce the concept of complementary work to describe labor that seeks to supplement existing workplace hierarchies. [ABSTRACT FROM AUTHOR]

The optical design of the Multi Conjugate Adaptive Optics RelaY for the Extremely Large Telescope experienced many modifications since Phase A conclusion in late 2009. These modifications were due to the evolution of the telescope design, the more and more accurate results of the performance simulations and the variations of the opto-mechanical interfaces with both the telescope and client instruments. Besides, in light of the optics manufacturing assessment feedbacks, the optical design underwent to a global simplification respect to the former versions. Integration, alignment, accessibility and maintenance issues took also a crucial role in the design tuning during the last phases of its evolution. This paper intends to describe the most important steps in the evolution of the optical design, whose rationale has always been to have a feasible and robust instrument, fulfilling all the requirements and interfaces. Among the wide exploration of possible solutions, all the presented designs are compliant with the high-level scientific requirements, concerning the maximum residual wavefront error and the geometrical distortion at the exit ports. The outcome of this decennial work is the design chosen as baseline at the kick-off of the Phase B in 2016 and subsequently slightly modified, after requests and inputs from alignment and maintenance side. [ABSTRACT FROM AUTHOR]

This article examines the effects of job task characteristics and job satisfaction on subjective well-being, often referred to as happiness, among Japanese employees. Because past research has recognized happiness as a source of greater performance, and on account of recent events related to karōshi (death by overwork), conditions in the workplace are of great interest for both research and practice. This research, using conditional process analysis with data gathered from Japanese managers and front-line workers within Japanese firms in Japan, found that job satisfaction fully mediates the relationship between job task characteristics and subjective well-being. Among job satisfaction factors, self-accomplishment and 'relatedness' (mutual respect and reliance with others) displayed the strongest mediating influences between job task characteristics and positive well-being. First, these findings suggest that companies cannot rely on job design alone to directly foster employee well-being but must ensure that task characteristics translate into work-related outcomes, such as job satisfaction. Second, at least for Japanese employees, careful attention must be paid to designing jobs that foster feelings of self-accomplishment and relatedness in order to enhance subjective well-being. These results indicate that job satisfaction plays a central role in the relationship between job design and well-being. [ABSTRACT FROM AUTHOR]

Objectives: In a clinical laboratory, the design of the workspace directs the workflow and significantly affects the productivity of clinical laboratory scientists (CLS). With the chronic shortage of CLS, a well-designed workspace is essential to take full advantage of available staff, especially in high-volume laboratories.Methods: Through the use of quality improvement tools, a manual body fluid testing workspace was redesigned to address weaknesses in the layout that led to excessive physical steps taken by staff.Results: System engineering tools such as a fishbone diagram, spaghetti diagrams, Plan-Do-Study-Act cycles, and a counterbalance measure were all used in a CLS-led quality improvement initiative to redesign a workspace in the manual body fluid processing area of a clinical laboratory at Mayo Clinic.Conclusions: After the redesign, physical steps taken and time to process body fluids were reduced by an average of 40% and 32%, respectively, demonstrating the utility of quality improvement tools in clinical laboratory settings. [ABSTRACT FROM AUTHOR]

The article discusses the steps of implementation of the direct oral anticoagulant (DOAC) therapy. Topics covered include the establishment of an interprofessional work group, the identification of access options for DOAC therapy and the creation of patient education materials. Also mentioned is the creation of the acute venous thromboembolism (VTE) program order set in the electronic medical record (EMR).

Motivation High-Throughput Sequencing technologies produce huge amounts of data in the form of short genomic reads, associated quality values and read identifiers. Because of the significant structure present in these FASTQ datasets, general-purpose compressors are unable to completely exploit much of the inherent redundancy. Although there has been a lot of work on designing FASTQ compressors, most of them lack in support of one or more crucial properties, such as support for variable length reads, scalability to high coverage datasets, pairing-preserving compression and lossless compression. Results In this work, we propose SPRING, a reference-free compressor for FASTQ files. SPRING supports a wide variety of compression modes and features, including lossless compression, pairing-preserving compression, lossy compression of quality values, long read compression and random access. SPRING achieves substantially better compression than existing tools, for example, SPRING compresses 195 GB of 25× whole genome human FASTQ from Illumina's NovaSeq sequencer to less than 7 GB, around 1.6× smaller than previous state-of-the-art FASTQ compressors. SPRING achieves this improvement while using comparable computational resources. Availability and implementation SPRING can be downloaded from https://github.com/shubhamchandak94/SPRING. Supplementary information Supplementary data are available at Bioinformatics online. [ABSTRACT FROM AUTHOR]

Background: Although automation has become widely utilized in certain areas of diagnostic testing, its adoption in diagnostic microbiology has proceeded much more slowly. Objective: To describe our real-world experience of integrating an automated instrument for diagnostic microbiology (Walk-Away Specimen Processor, WASPLab) within a model of total laboratory automation (TLA). Methods: The implementation process was divided into 2 phases. The former period, lasting approximately 6 weeks, entailed the installation of the WASPLab processor to operate as a standalone instrumentation, whereas the latter, lasting approximately 2 weeks, involved physical connection of the WASPLab with the automation. Results: Using the WASPLab instrument in conjunction with the TLA model, we obtained a time savings equivalent to the work of 1.2 full-time laboratory technicians for diagnostic microbiology. The connection of WASPLab to TLA allowed its management by a generalist or clinical chemistry technician, with no need for microbiology skills on the part of either worker. Hence, diagnostic microbiology could be performed by the staff that is already using the TLA, extending their activities to include processing urgent clinical chemistry and hematology specimens. The time to result was also substantially improved. Conclusions: According to our experience, using the WASPLab instrument as part of a TLA in diagnostic microbiology holds great promise for optimizing laboratory workflow and improving the quality of testing. [ABSTRACT FROM AUTHOR]

Background: Research findings on the relationship between the psychosocial work environment and leisure-time physical activity (LTPA) are equivocal. This might partly be due to studies having focused on a restricted set of psychosocial dimensions, thereby failing to capture all relevant domains. Aims: To examine cross-sectional associations between seven psychosocial work environment domains and LTPA in a large sample of UK civil servants and to profile LTPA and consider this in relation to UK government recommendations on physical activity. Methods: In 2012 Northern Ireland Civil Service employees completed a questionnaire including measures of psychosocial working conditions (Management Standards Indicator Tool) and LTPA. We applied bivariate correlations and linear regression analyses to examine relations between psychosocial working conditions and LTPA. Results: Of 26 000 civil servants contacted, 5235 (20%) completed the questionnaire. 24% of men and 17% of women reported having undertaken 30 min or more of physical activity on five or more days in the past week. In men, job control (-0.08) and peer support (-0.05) were weakly but significantly negatively correlated with LTPA, indicating that higher levels of exposure to these psychosocial hazards was associated with lower levels of LTPA. Job role (-0.05) was weakly but significantly negatively correlated with LTPA in women. These psychosocial work characteristics accounted for 1% or less of the variance in LTPA. Conclusions: Longitudinal research to examine cause-effect relations between psychosocial work characteristics and LTPA might identify opportunities for psychosocial job redesign to increase employees' physical activity during leisure time. [ABSTRACT FROM AUTHOR]

Focus of Presentation People with disability experience inequality in relation to social determinants of health such as employment, education and housing. Under the UN Convention on the Rights of Persons with Disabilities, Australia must collect data to assess fulfilment of its Convention obligations and to identify and address barriers faced by people with disability in exercising their rights. The objective of our research was to determine the extent to which such data are currently available. Findings With input from people with disability, we developed a monitoring framework and indicators to measure inequalities between Australians with and without disability in relation to social determinants of health. National data sources that included a disability identifier were available to report on 73% of the 128 indicators. For example, in the domain 'Employment', national data were available for indicators of labour force status, long-term unemployment, leave entitlements, and employment in high-skill jobs. Data were not available for the following indicators: under-employment, access to job design modifications, and disability-related discrimination in the workplace. Conclusions/Implications It is currently not possible to quantify inequalities between Australians with and without disability, track change over time, or identify factors that can inform effective policy responses for indicators where we lack national data that include a disability identifier. Key messages Addressing data gaps, including by facilitating disability identification in existing data collections, is essential for tackling disability-related inequalities on social determinants of health and meeting our obligations under the UN Convention on the Rights of Persons with Disabilities. [ABSTRACT FROM AUTHOR]