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Traditional fermented foods are known to offer cardiovascular health benefits. However, the potential of fermented Chinese chives (FCC) in reducing coronary heart disease (CHD) remains unclear. This study employed anaerobic fermentation to investigate Lactiplantibacillus plantarum (L. plantarum) P470 from FCC. The results indicated that L. plantarum P470 enhanced hydroxyl radical scavenging and exhibited anti-inflammatory effects on RAW264.7 macrophages in the fecal fermentation supernatant of CHD patients. These effects were attributed to the modulation of gut microbiota and metabolites, including short-chain fatty acids (SCFAs). Specifically, L. plantarum P470 increased the abundance of Bacteroides and Lactobacillus while decreasing Escherichia-Shigella, Enterobacter, Veillonella, Eggerthella, and Helicobacter in CHD patient fecal samples. Furthermore, L. plantarum P470 regulated the biosynthesis of unsaturated fatty acids and linoleic acid metabolism. These findings suggest that L. plantarum P470 from FCC can improve the fecal physiological status in patients with CHD by modulating intestinal microbiota, promoting SCFA production, and regulating lipid metabolism. [ABSTRACT FROM AUTHOR]

It has been strongly suggested that selenium deficiency and T-2 toxin contamination have a strong relationship with the occurrence and development of Kashin–Beck disease (KBD). In order to provide information for understanding the high prevalence of KBD in Tibet, this study collected the responses to a cubital venous blood and dietary questionnaire of 125 subjects including 75 KBD patients and 50 healthy controls in a KBD-prevalent county (Luolong County) in Tibet, China. A total of 10 household local families were randomly selected in this area, and local diet samples of brick tea, Zanba powder, milk residue, and hulless Barley were collected from these residents. Selenium content in blood was detected by inductively coupled plasma mass spectrometry (ICP-MS). The T-2 toxin contamination level in food sample was assayed using an ELISA kit. The selenium levels of patients and controls were 42.0 ± 19.8 and 56.06 ± 22.4 μg/L, respectively. The serum selenium level in controls was higher than that in patients, but there was no significant difference, and the serum selenium level both in patients and controls in Tibet was lower than the normal range. The results of the dietary survey showed that the number of respondents who consumed butter tea was large; 46.67% of patients indicated that they drank buttered tea every day, which was significantly higher than in controls. The contents of T-2 toxin in Zanba powder, milk residue, hulless barley and drinking water samples were below the detection limit (0.05 μg/kg); this result was labeled Tr. Unexpectedly, the contents of T-2 toxin in brick tea were higher, with average levels of 424 ± 56 μg/kg in Detong village and 396 ± 24 μg/kg in Langcuo village. For the first time, we report the presence of an extremely high concentration of T-2 toxin in brick tea of Tibet. [ABSTRACT FROM AUTHOR]

In the context of global climate change and urban expansion, urban residents are encountering greater rainstorm waterlogging risk. Quantifying population exposure to rainstorms is an important component of rainstorm waterlogging risk assessments. This study utilized a two-dimensional hydrodynamic model to simulate the inundation water depth and inundation area resulting from rainstorms, with return periods of 5, 10, 50, and 100 years, in the Xiong'an New Area, and overlaid the gridded population data in 2017 and in 2035 under SSP2 to assess the change in population exposure. The results show that the average inundation depth and area increase were from 0.11 m and 207.9 km2 to 0.18 m and 667.2 km2 as the rainstorm return period increased from once in 5 years to once in 100 years. The greatest water depths in the main urban areas were mainly located in the low-lying areas along the Daqing River. The total population exposed to rainstorm waterlogging for the 5-, 10-, 50-, and 100-year return periods was 0.31, 0.37, 0.50, and 0.53 million, respectively, in 2017. However, this is projected to rise significantly by 2035 under SSP2, increasing 2–4-fold compared with that in 2017 for the four return periods. Specifically, the projected population exposure is expected to be 0.7, 1.0, 1.8, and 2.0 million, respectively. The longer the return period, the greater the increase in population exposure. The proportion of the population exposed at the 0.05–0.2 m water depth to the total population exposure decreases as the return periods increases, whereas the proportion changes in the opposite direction at the 0.2–0.6 m and >0.6 m depth intervals. Spatially, high-exposure areas are concentrated in densely populated main urban regions in the Xiong'an New Area. In the future, more attention should be paid to densely populated low-lying areas and extreme recurrence rainstorm events for urban flood-risk management to ensure population safety and sustainable urban development. [ABSTRACT FROM AUTHOR]

In the electronic brake system (EBS) of commercial vehicles, due to the compressibility of gas, it is difficult to achieve accurate control in the pneumatic pipeline. To address this issue, a vertical load estimator based on unscented particle filtering (UPF) was designed, which can estimate vertical load during the running of the vehicle. Then, the EBS dynamics model was established based on software, including a brake signal sensor, single-channel bridge control module, ABS solenoid valve, and dual-channel bridge control module. Finally, based on the characteristics of the EBS valve, the control algorithm of the valve was studied, and the algorithm was tested using a hardware-in-the-loop experiment. The experiment results showed that the designed algorithm could improve braking performance. [ABSTRACT FROM AUTHOR]

Intestinal diseases caused by sleep deprivation (SD) are severe public health threats worldwide. However, whether or not probiotics attenuate the intestinal damage associated with SD remains unclear. In this study, we used antibiotic pretreatment and fecal microbiota transplantation to investigate the protective role of Lactiplantibacillus plantarum (L. plantarum) 124 against SD-related intestinal barrier damage in C57BL/6 mice. Compared with those of a normal sleeping mouse, we observed that intestinal antioxidant capacity and anti-inflammatory cytokine levels were decreased, while pro-inflammatory cytokines were increased in sleep deprivation mice with an increasing duration of sleep deprivation. This resulted in decreased tight junction protein expression and increased intestinal barrier permeability. In contrast, intragastric administration with L. plantarum 124 reversed SD-associated intestinal oxidative stress, inflammation, colonic barrier damage, and the dysbiosis of the microbiota in the colon. In addition, L. plantarum 124 restored gut microbiota homeostasis via restoring abundance, including that of Dubosiella, Faecalibaculum, Bacillus, Lachnoclostridium, and Bifidobacterium. Further studies showed that gut microbiota mediated SD-associated intestinal damage and the treatment L. plantarum 124 in SD-associated colonic barrier damage. L. plantarum 124 is a potential candidate for alleviating SD-associated intestinal barrier damage. Overall, L. plantarum 124 consumption attenuates intestinal oxidative stress, inflammation, and intestinal barrier damage in SD-associated mice via the modulation of gut microbes. [ABSTRACT FROM AUTHOR]

Plant viruses, as obligate intracellular parasites, induce significant changes in the cellular physiology of host cells to facilitate their multiplication. These alterations often lead to the development of symptoms that interfere with normal growth and development, causing USD 60 billion worth of losses per year, worldwide, in both agricultural and horticultural crops. However, existing literature often lacks a clear and concise presentation of the key information regarding the mechanisms underlying plant virus-induced symptoms. To address this, we conducted a comprehensive review to highlight the crucial interactions between plant viruses and host factors, discussing key genes that increase viral virulence and their roles in influencing cellular processes such as dysfunction of chloroplast proteins, hormone manipulation, reactive oxidative species accumulation, and cell cycle control, which are critical for symptom development. Moreover, we explore the alterations in host metabolism and gene expression that are associated with virus-induced symptoms. In addition, the influence of environmental factors on virus-induced symptom development is discussed. By integrating these various aspects, this review provides valuable insights into the complex mechanisms underlying virus-induced symptoms in plants, and emphasizes the urgency of addressing viral diseases to ensure sustainable agriculture and food production. [ABSTRACT FROM AUTHOR]

Due to their superior antibacterial properties, biocompatibility and high conductivity, nanomaterials have shown a broad prospect in the biomedical field and have been widely used in the prevention and treatment of oral diseases. Also due to their small particle sizes and biodegradability, nanomaterials can provide solutions for tissue engineering, especially for oral tissue rehabilitation and regeneration. At present, research on nanomaterials in the field of dentistry focuses on the biological effects of various types of nanomaterials on different oral diseases and tissue engineering applications. In the current review, we have summarized the biological effects of nanoparticles on oral diseases, their potential action mechanisms and influencing factors. We have focused on the opportunities and challenges to various nanomaterial therapy strategies, with specific emphasis on overcoming the challenges through the development of biocompatible and smart nanomaterials. This review will provide references for potential clinical applications of novel nanomaterials in the field of oral medicine for the prevention, diagnosis and treatment of oral diseases. [ABSTRACT FROM AUTHOR]

Airborne synthetic aperture radar (SAR) is susceptible to atmospheric disturbance and other factors that cause the position offset error of the antenna phase center and motion error. In close-range detection scenarios, the large elevation angle may make it impossible to directly observe areas near the underlying plane, resulting in observation blind spots. In cases where the illumination elevation angle is extremely large, the influence of range variant envelope error and phase modulations becomes more serious, and traditional two-step motion compensation (MOCO) methods may fail to provide accurate imaging. In addition, conventional phase gradient autofocus (PGA) algorithms suffer from reduced performance in scenes with few strong scattering points. To address these practical challenges, we propose an improved phase-weighted estimation PGA algorithm that analyzes the motion error of UAV SAR under a large elevation angle, providing a solution for high-order range variant motion error. Based on this algorithm, we introduce a combined focusing method that applies a threshold value for selection and optimization. Unlike traditional MOCO methods, our proposed method can more accurately compensate for spatially variant motion error in the case of scenes with few strong scattering points, indicating its wider applicability. The effectiveness of our proposed approach is verified by simulation and real data experimental results. [ABSTRACT FROM AUTHOR]

The tailwater tunnel of the Wuyue pumped storage power station is located in bedrock and extends to depths between tens and hundreds of meters. It is impossible to analyze and evaluate the whole engineering area from geological exploration data, and the hydrogeological conditions are complicated. In the early stages of the tailwater tunnel's construction, the drinking water wells in four villages dried up. This paper reports the results from a field investigation, in situ tests, laboratory tests, and numerical simulation carried out to determine how the groundwater was affected when the tunnel was excavated. A hydrogeological model of the region was established from the inverted regional natural flow field parameters. The model was validated, and an analysis of the errors showed that there was an average error of 1.98% between the natural flow field and the hydrogeological survey flow field. The model was then used to simulate the three-dimensional transient seepage fields under normal seepage conditions and limited seepage conditions, as far as was practical. The results showed that, as the excavation of the tailwater tunnel advanced, the water inflow to the tunnel also increased. When the water inflow increased from 1000 to 5000 m3/d, the water level at a distance of 100 m from the axis of the tunnel dropped from −0.956 to −1.604 m. We then analyzed how the water level changed as the water inflow varied and proposed a formula for calculating the extent of the influence on the groundwater. We studied how the water level changed at different well points to ascertain how a groundwater well became depleted and determined the factors that influenced seepage in the regional flow field. The water level in different areas of the project area was simulated and analyzed, and the extent of the groundwater area affected by the tunnel construction was clarified. We then studied how the groundwater in different areas of, and distances from, the project area was influenced by normal seepage conditions and limited seepage conditions and proposed a formula for calculating the extent of the influence on groundwater for different water inflows. We constructed a 'smart site' for visualizing data, sharing information, and managing the project. Time–frequency domain analysis was applied to explore the extent of the impacts and range of the vibration effects on residential housing at different distances from the project area caused by the different methods for excavating the tailwater tunnel. The results from this analysis will provide useful insights into how the excavation of this tailwater tunnel will impact the local residents and living areas. [ABSTRACT FROM AUTHOR]

The dynamics parameters cause sudden change during the damage of the structural plane of landslide perilous rocks, and these can be easily accessed. Therefore the changes in dynamics parameters can effectively achieve early identification, stability evaluation, and monitoring and pre-alarming of the perilous rocks. Seven kinds of dynamic indexes, such as pulse indicator, margin index, the center of gravity frequency, root mean square frequency, impact energy, relative energy of the first frequency band, and damping ratio, are introduced and the early identification of landslide perilous rock is achieved based on the support vector machines (SVM) model, improved by particle swarm optimization algorithm. A laser vibrometer collected seven dynamic indexes of two rock masses on the reservoir bank slope in Baihebao Reservoir, China. Based on the particle group optimization algorithm optimization support vector (PSO–SVM) perilous rocks recognition model, and seven dynamic indicators, the stability of two rock masses was recognized with high efficiency and accuracy. The identification results were consistent with the landslide perilous rock identification results based on natural vibration frequency, and the results verify the accuracy of the PSO–SVM perilous rocks identification model. The results show that the sensitivity order of each identification index is: root mean square frequency > margin index > relative energy of the first frequency band > center of gravity frequency > impact energy > pulse indicator > damping ratio. The accuracy of the multi-dynamics parameters landslide perilous rock mass identification model can be improved by selecting appropriate dynamic indexes with good sensitivity. The research results have high theoretical significance and application value for early identification of landslide perilous rocks, stability evaluation, and safety monitoring, and early warning. [ABSTRACT FROM AUTHOR]

Understanding the brittle fracture behavior of rock is crucial for engineering and Earth science. In this paper, based on acoustic emission (AE) and laser Doppler vibration (LDV) monitoring technology, the staged damage behaviors of rock-like materials with different brittleness degrees under uniaxial compression are studied via multiple parameters. The results show that the brittleness degree determines the fracture mode. As the specimen's brittleness degree increases, the tensile failure increases and shear failure decreases. AE activity is enhanced at the crack damage point. With an increasing specimen brittleness degree, different instability precursor information is shown during the unstable crack growth stage: the AE b value changes from the fluctuating to continuously decreasing state, and the natural frequency changes from the stable fluctuation to upward fluctuation state. The AE b value near the stress drop is the smallest, and it decreases with an increasing brittleness degree. The natural frequency reduction indicates the rock-like fracture. The natural frequency is a symbolic index that reflects staged damage characteristics and predicts the amount of energy released by brittle failure. These findings provide guidelines for rock stability monitoring and provide support for better responses to stability evaluations of rock slopes, rock collapses, and tunnel surrounding rock in engineering. [ABSTRACT FROM AUTHOR]

Perilous rock instability on the soil slope brings a substantial threat to project operation and even people's lives. The buried depth of the perilous rock is a challenge to deal with and primarily determines its stability, and the indirect rapid identification of its buried depth is the key to its stability evaluation. The paper aims to find a new and quick method to measure the buried depth of perilous rock on the soil slope and to solve the hard-to-measure buried depth stability evaluation. When the damping ratio is less than one, and the deformation is linear elastic throughout the amplitude range, the potentially perilous rock vibration model may reduce to a multi-degree-of-freedom vibration one. By theoretical deduction, a quantitative relationship is established among the perilous rock mass, the basement response coefficient, the buried depth of the perilous rock, and the natural horizontal vibration frequency. In addition, the accuracy of this relationship is confirmed via numerous indoor experiments, showing that the horizontal vibration frequency of the perilous rock model in one dimension increases as the buried depth increases. Finally, based on the natural vibration frequency and guided by the limit balance model, a stability evaluation model of the perilous rock on the soil slope is constructed. Hence, the example shows that the method is feasible. The research findings are of vital significance for the stability evaluation of the perilous rock on the soil slope and give a novel approach and theoretical foundation for quick identification and monitoring. [ABSTRACT FROM AUTHOR]

Rice black-streaked dwarf virus (RBSDV) is the main pathogen causing maize rough dwarf disease (MRDD) in China. Typical enation symptoms along the abaxial leaf veins prevail in RBSDV-infected maize inbred line B73 (susceptible to RBSDV), but not in X178 (resistant to RBSDV). Observation of the microstructures of epidermal cells and cross section of enations from RBSDV-infected maize leaves found that the increase of epidermal cell and phloem cell numbers is associated with enation formation. To identify proteins associated with enation formation and candidate proteins against RBSDV infection, comparative proteomics between B73 and X178 plants were conducted using isobaric tags for relative and absolute quantitation (iTRAQ) with leaf samples at the enation forming stage. The proteomics data showed that 260 and 316 differentially expressed proteins (DEPs) were identified in B73 and X178, respectively. We found that the majority of DEPs are located in the chloroplast and cytoplasm. Moreover, RBSDV infection resulted in dramatic changes of DEPs enriched by the metabolic process, response to stress and the biosynthetic process. Strikingly, a cell number regulator 10 was significantly down-regulated in RBSDV-infected B73 plants. Altogether, these data will provide value information for future studies to analyze molecular events during both enation formation and resistance mechanism to RBSDV infection. [ABSTRACT FROM AUTHOR]

In this study, through simple ammonia impregnation, more amine functional groups could be introduced into the zeolite 4A synthesized using fly ash, which efficiently improved the mercury ion removal capacity of modified zeolites. The impregnation-modification mechanism of NH3·H2O, ammonium chloride, and silane coupling agent (KH792) for zeolite 4A, and the Hg2+ ion removal-efficiency by aminated zeolites, were studied and compared. Through ion exchange and hydroxyl reactions, NH3·H2O impregnation introduced the same kinds of nitrogen-containing groups into zeolite as KH792 grafting, which was more than the NH4Cl modification. The Hg2+ ion adsorption capacity of NH3·H2O-zeolite was higher than those of KH792-zeolite and NH4Cl-zeolite through ion exchange and the complexation of nitrogen-containing groups. When coexisting with Pb2+, Cu2+, and Zn2+ ions, the Hg2+ ion removal rate of NH3·H2O-zeolite was still higher than 99%. After five adsorption and desorption cycles, the Hg2+ ion removal rate of NH3·H2O-zeolite was 72.03%. When NH3·H2O-zeolite was added to the leaching of mercury-contaminated soil, the content of soluble mercury significantly decreased. Therefore, we synthesized a potential cheap and safe adsorbent using fly ash as the main raw material through the simple NH3·H2O impregnation modification for the treatment of mercury-contaminated water and soil. [ABSTRACT FROM AUTHOR]

Vegetation slope protection is widely used in slope support engineering as an ecologically friendly support method. There has been a lot of research on herbs and shrubs slope protection, but less on arbor slope protection. Using accumulation landslides as a research subject, a series of physical model tests of arbor slope protection were conducted, using a combination of various monitoring technologies and 3D printing technology that can produce realistic root models. The slope protection effect of arbors and the synergistic characteristics of accumulation landslides were explored using a preliminary analysis. We found that, with the support of arbor roots, (1) the peak-start stage, second peak stage, variable attenuation stage, and linear attenuation stage were the four stages of the anti-sliding force curve. The peak value of anti-sliding force on a slope with root protection increased, and the time it took to reach the peak value increased dramatically. Furthermore, after attaining the peak value, the degree of anti-sliding force attenuation was diminished. (2) The slope displacement showed a downward trend. Moreover, the coefficient of variation of displacement curves in different parts decreased, and slope integrity was enhanced. (3) The degree of slope crack growth diminished, resulting in an arch stress area and improved anti-sliding capacity. (4) There was an apparent "synergetic" tendency in the evolution process of accumulation landslides. Furthermore, the anti-sliding force and displacement curves in different parts had a good correspondence. [ABSTRACT FROM AUTHOR]

Background: Fermented milk is beneficial for metabolic disorders, while the underlying mechanisms of action remain unclear. This study explored the benefits and underlying mechanisms of Bifidobacterium longum 070103 fermented milk (BLFM) in thirteen-week high-fat and high-sugar (HFHS) fed mice using omics techniques. Methods and results: BLFM with activated glucokinase (GK) was screened by a double-enzyme coupling method. After supplementing BLFM with 10 mL/kg BW per day, fasting blood glucose, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and leptin were significantly reduced compared with the HFHS group. Among them, the final body weight (BW), epididymal fat, perirenal fat, and brown fat in BLFM group had better change trends than Lacticaseibacillus rhamnosus GG fermented milk (LGGFM) group. The amplicon and metabolomic data analysis identified Bifibacterium as a key gut microbiota at regulating glycolipid metabolism. BLFM reverses HFHS-induced reduction in bifidobacteria abundance. Further studies showed that BLFM significantly reduces the content of 3-indoxyl sulofphate associated with intestinal barrier damage. In addition, mice treated with BLFM improved BW, glucose tolerance, insulin resistance, and hepatic steatosis. Conclusion: BLFM consumption attenuates obesity and related symptoms in HFHS-fed mice probably via the modulation of gut microbes and metabolites. [ABSTRACT FROM AUTHOR]

To consolidate the achievements in the elimination of absolute poverty in China and prevent rural populations from returning to poverty as a result of meteorological disasters, this study analyzed the spatiotemporal characteristics of rainstorms and droughts and their socioeconomic impacts on China's contiguous poverty-stricken areas (CPSAs) from 1984 to 2019. The annual number of rainstorms and drought days in CPSAs of China reached approximately 1.9 days/year and 44.6 days/year, respectively. It gradually decreased from southeast to northwest. Rainstorms showed a significant increasing trend of 0.075 days/decade, while there is no significant trend in drought days. Due to rainstorms and droughts, the average annual number of people affected and direct economic losses in CPSAs reached 34 million people/year and 29 billion Chinese yuan/year, accounting for 22.9% and 12.6% of China's total amounts, respectively. The average annual loss rate due to disasters in this region reached 1.6%, which is 0.6% higher than the national level. Furthermore, the distinct features and socioeconomic impacts of rainstorms and droughts were identified on the southeastern and northwestern sides of the population density line (PDL) along Tengchong-Aihui in China. Droughts have often impacted the regions located along the PDL, while rainstorms and droughts have occurred more frequently in the regions to the southeast of the PDL than in the regions to the northwest of the PDL. As a result, the affected population and direct economic losses due to rainstorms and droughts in the regions to the southeast of the PDL were 8.8 and 9.2 times and 3.3 and 7.4 times higher, respectively, than those in the regions on the other side of the PDL. Although the losses were greater, the disaster resistance capabilities were significantly improved in these regions. In contrast, the regions to the northwest side of the PDL exhibited a significant increasing trend in losses with a relatively low disaster resistance capabilities. This study revealed that it is necessary to improve the capability of meteorological disaster prevention and reduction in China's CPSAs, especially in the regions to the west of the PDL, which could further contribute to the realization of United Nations Sustainable Development Goals. [ABSTRACT FROM AUTHOR]

In order to find the causes of statistical line loss abnormalities and propose better loss reduction strategies, it is necessary to improve the accuracy of theoretical line loss calculations. Since Distributed Generation (DG) access to the distribution network causes variability of power flow in the distribution network within a short period, the error of the traditional line loss calculation method increases. For the line loss calculation of medium-voltage distribution networks containing DGs with high-density collection data, a continuous line loss calculation method for the distribution network was proposed, aiming at improving the accuracy compared with the traditional line loss calculation method. The proposed method makes full use of the high-density collection data on the dispatch side and DG side, distributing the supply power to each load node by power to calculate real-time power flow, thus obtaining a more credible line loss value. The effectiveness and accuracy of the proposed method were verified in the IEEE 17-node distribution system. [ABSTRACT FROM AUTHOR]

Expression and purification of β-galactosidases derived from Bifidobacterium provide a new resource for efficient lactose hydrolysis and lactose intolerance alleviation. Here, we cloned and expressed two β-galactosidases derived from Bifidobacterium. The optimal pH for BLGLB1 was 5.5, and the optimal temperature was 45 °C, at which the enzyme activity of BLGLB1 was higher than that of commercial enzyme E (300 ± 3.6 U/mg) under its optimal conditions, reaching 2200 ± 15 U/mg. The optimal pH and temperature for BPGLB1 were 6.0 and 45 °C, respectively, and the enzyme activity (0.58 ± 0.03 U/mg) under optimum conditions was significantly lower than that of BLGLB1. The structures of the two β-galactosidase were similar, with all known key sites conserved. When o-nitrophenyl-β-D-galactoside (oNPG) was used as an enzyme reaction substrate, the maximum reaction velocity (Vmax) for BLGLB1 and BPGLB1 was 3700 ± 100 U/mg and 1.1 ± 0.1 U/mg, respectively. The kinetic constant (Km) of BLGLB1 and BPGLB1 was 1.9 ± 0.1 and 1.3 ± 0.3 mmol/L, respectively. The respective catalytic constant (kcat) of BLGLB1 and BPGLB1 was 1700 ± 40 s−1 and 0.5 ± 0.02 s−1, respectively; the respective kcat/Km value of BLGLB1 and BPGLB1 was 870 L/(mmol∙s) and 0.36 L/(mmol∙s), respectively. The Km, kcat and Vmax values of BLGLB1 were superior to those of earlier reported β-galactosidase derived from Bifidobacterium. Overall, BLGLB1 has potential application in the food industry. [ABSTRACT FROM AUTHOR]

Traditional materials such as fly ash and lime are generally used to improve soils but can severely pollute the environment. Eco-friendly protocols, such as the application of xanthan gum, are therefore essential for soil treatment. In this study, a series of microscopic tests, water retention characteristics tests, and shear tests were carried out on silt, which are known to have poor engineering properties, to explore the effect and mechanism of xanthan gum treatment on the water retention and shear strength characteristics of silt during the wetting process. The results show that the water retention capacity of the treated silt increases with increasing xanthan gum content, and a hysteresis effect is clearly observed. The cohesion and internal friction angle of the silt strongly decrease with increasing water content, and the strength significantly weakens. However, the strength of the silt treated with xanthan gum is consistently higher than that of the untreated silt. The microscopic tests show that soil pores are gradually filled by xanthan gum with good water-retaining properties, thus significantly enhancing the water retention capacity. Furthermore, the hydrogel that cements the soil particles forms by the bonding effects between xanthan gum and soil particles, which greatly improves the silt strength. [ABSTRACT FROM AUTHOR]

Data collection is more difficult in distribution network than transmission networks since the structure of distribution networks is more complex. As a result, data could be partly abnormal or missing, which cannot completely describe the operation status of distribution network. In addition, access of distributed generation (DG) to distribution network further aggravates the variability of power flow in distribution network. The traditional deterministic line loss calculation method has some limitations in accurately estimating the line loss of distribution network with DG. A line loss interval calculation method based on power flow calculation and linear optimization is proposed, considering abnormal data collection and distribution network power flow variability. The linear optimization model is established according to sensitivity of line loss to the injected power and sensitivity of transmission power of first branch to the injected power. Introducing the scheduling information into the optimization model, a reliable line loss fluctuation interval can be obtained which actual line loss locates. The effectiveness of the proposed algorithm is verified in IEEE 33-bus distribution network system. [ABSTRACT FROM AUTHOR]

There are many methods or indicators used for evaluating the nutritional value of foods; however, it is difficult to accurately reflect the comprehensive nutritional value of a food with a single indicator, and a systematic evaluation system is lacking. In this article, we systematically summarize the common evaluation methods and indicators of the nutritional value of foods. The purpose of this review was to establish an evaluation procedure for nutritional properties of foodstuffs and to help scientists choose more direct and economical evaluation methods according to food types or relevant indicators. The procedure involves the selection of a three-level evaluation method that covers the whole spectrum of a food's nutritional characteristics. It is applicable to scientific research in the fields of agricultural science, food science, nutrition, and so on. [ABSTRACT FROM AUTHOR]

Grouped buckets are an important type of foundation for offshore structures. Because of interactions between buckets, jacked penetration above a group of two buckets is a complicated process that involves complex bucket-soil interactions. In this study, non-contact digital image correlation was applied to study the deformation of sandy soil during jacked penetration. Bucket-group efficiency is negatively correlated with sand density and bucket diameter, and the incremental filling ratio is negatively correlated with sand density and positively correlated with bucket diameter. The graph of the incremental filling ratio versus penetration depth curves is a polyline for a bucket diameter of 5 cm and a hyperbola for 7.5 cm. Buckets in groups experience superposition of their deformation fields, which leads to a partial loss of shear strength. Sand density, bucket diameter, and bucket spacing markedly influence the deformation field of a bucket group, consistent with the force-displacement curves. The bucket-group effect retards the formation of a soil plug. [ABSTRACT FROM AUTHOR]

Potential evapotranspiration (PET) is an important factor that needs to be considered in regional water management and allocation; thus, the reasonable estimation of PET is an important topic in hydrometeorology and other related fields. There is evidence that increased CO2 concentration alters the physiological properties of vegetation and thus affects PET. In this study, changes in PET with and without the CO2 effect over China is investigated using seven CMIP6-GCMs outputs under seven shared socioeconomic pathways (SSPs) based scenarios (SSP1-1.9, SSP1-2.6, SSP2-4.5, SSP3-7.0, SSP4-3.4, SSP4-6.0, and SSP5-8.5), as well as the contribution rate of CO2 on PET in different climatic regions. Changes in estimated PET based on modified Penman–Monteith (PM) method that considers the CO2 effect is compared with the traditional PM method to examine how PET quantity varies (differences) between these two approaches. The results show that the PET values estimated by the two methods explored opposite trends in 1961–2014 over entire China; it decreases with consideration of CO2 but increases without consideration of CO2. In the future, overall PET is projected to increase under all scenarios during 2015–2100 for China and its three sub-regions. PET generally tends to grow slower when CO2 is taken into account (modified PM approach), than when it is not (traditional PM method). In terms of differences in the estimated PET by the two methods, the difference between the two adopted methods increased in China and its sub-regions for the 1961–2014 period. In the future, the difference in estimated PET is anticipated to continuously increase under SSP3-7.0 and SSP5-8.5. Spatially, a much greater extent of difference is found in the arid region. Across the arid region, the PET difference is projected to be the highest at 138% in the mid-term (2041–2060) with respect to the 1995–2014 period, whereas it tends to increase slower in the long-term period (2081–2100). Importantly, CO2 is found to be the most dominant factor (−154.2% contribution) to have a great effect on PET changes across the arid region. Our findings suggest that ignorance of CO2 concentration in PET estimation will result in significant overestimation of PET in the arid region. However, consideration of CO2 in PET estimation will be beneficial for formulating strategies on future water resource management and sustainable development at the local scale. [ABSTRACT FROM AUTHOR]

We explore the feasibility of the long-term transportation of live large yellow croakers (Pseudosciaena crocea) using the combined method of CO2 anesthesia and hypothermia hibernation, and its effect on the quality of recovered fish stored at 4 °C. Fish treated with CO2 anesthesia at a 2 ppm/s aeration rate were cooled at 3 °C/h to hibernate survived for 36 h at 8 °C in seawater. This method resulted in better survival rates and time, and a lower operational time than hypothermia hibernation or CO2 anesthesia methods. The results of a blood analysis indicated that the stress experienced by the fish during hibernation was mitigated, but existent after recovery. The drip loss rate of the ordinary muscle of hibernated fish was significantly different from that of the control group at 4 °C, but there was no significant difference in the pH, lactic acid content, and color during early storage. Furthermore, hibernation did not affect springiness and chewiness. Thus, the combination of CO2 anesthesia and hibernation may improve the survival and operation efficiency of fish in long-term transportation. However, this method affects the quality of fish after long-term storage. Thus, hibernated fish should be consumed after appropriate domestication or immediately after recovery. [ABSTRACT FROM AUTHOR]

China has experienced a huge socioeconomic advancement over the past few decades, resulting in great change in land use and land cover. To date, negligible attention has been given to examining the socioeconomic changes in the context of land-use change, especially from a futuristic standpoint. However, motivated by China's latest carbon neutrality target, this study analyzes the prospective changes in socioeconomic status, and carbon dioxide emission in the context of future land-use change, focusing on three future periods: 2026–2030 (carbon dioxide peak phase), 2056–2060 (carbon-neutral phase), and 2080–2099 (long-term period). In this regard, recently published land-use products under seven Shared Socioeconomic Pathways-based scenarios (SSP1-1.9, SSP1-2.6, SSP4-3.4, SSP2-4.5, SSP4-6.0, SSP3-7.0, and SSP5-8.5) as part of the CMIP6, as well as the projected GDP and population under five socioeconomic scenarios are used. To estimate socioeconomic change over prominent land-use types (urban), we combined five socioeconomic scenarios with seven corresponding SSPs-based land-use change scenarios (SSP1 with SSP1-1.9 and SSP1-2.6; SSP2 with SSP2-4.5; SSP3 with SSP3-7.0; SSP4 with SSP4-3.4 and SSP4-6.0; and SSP5 with SSP5-8.5 scenarios). Our results reveal that rapid urban land expansion in the future is the most dominant aspect in China. In the carbon neutrality phase (2056–2060), urban land is expected to expand ~80% more than that of the reference period (1995–2014). In the spatial aspect, the expansion of urban land is mainly prominent in the eastern and central parts of China. For socioeconomic changes, the most prominent increase in the urban population is estimated at 630.8% under SSP5-8.5 for the 2056–2060 period compared to the reference period. Regarding GDP for the urban area, industrial GDP will be higher than service GDP in the carbon emission peak phase (2026–2030), but it is projected to be overtaken by service GDP for the carbon-neutral target (2056–2060) and long-term periods (2080–2099). Further, the CO2 emission in China was found to increase with intensified urban land for the historical period (1995–2019). In the future, the largest increase in CO2 emission from the urban area is anticipated under SSP5-8.5 in the carbon-neutral target (2056–2060) phase, while CO2 emission will largely decline after (2056–2060) under SSP1-1.9, SSP1-2.6, and SSP4-3.4. Importantly, population change is expected to be the most predominant factor in future urban land expansion in China. These findings highlight the importance of well-governed urban-land development as a key measure to achieve China's carbon neutrality goal. [ABSTRACT FROM AUTHOR]

The extracellular secreted protein of Bifidobacterium longum (B. longum) plays an important role in maintaining the homeostasis of the human intestinal microenvironment. However, the mechanism(s) of interaction remain unclear. Lysozyme is a kind of antibacterial peptide. In this study, the amino acid sequence of a lysozyme-like protein of B. longum based on whole-genome data of an isolate from human gut feces was found. We further predicted functional domains from the amino acid sequence, purified the protein, and verified its bioactivity. The growth of some bacteria were significantly delayed by the 020402_LYZ M1 protein. In addition, the gut microbiota was analyzed via high-throughput sequencing of 16S rRNA genes and an in vitro fermentation model, and the fluctuations in the gut microbiota under the treatment of 020402_LYZ M1 protein were characterized. The 020402_LYZ M1 protein affected the composition of human gut microbiota significantly, implying that the protein is able to communicate with intestinal microbes as a regulatory factor. [ABSTRACT FROM AUTHOR]

Let G be a group. D p (G) = ⋂ H ≤ G N G (H ′ (p)) is defined and, the properties of D p (G) are investigated. It is proved that D p (G) = P [ A ] , where P = D (P) is the Sylow p-subgroup and A = N (A) is a Hall p ′ -subgroup of D p (G) , respectively. Furthermore, it is proved in a group G that (1) D p (G) = 1 if and only if C G (G ′ (p)) = 1 ; (2) O p ′ (D p (G)) ≤ Z ∞ (O p (G)) and (3) if Z (G ′ (p)) = 1 , then C G (G ′ (p)) = D p (G) . [ABSTRACT FROM AUTHOR]

Large-scale multispectral remote sensing data are often unavailable for some practical applications. Spectral resolution enhancement for large-scale multispectral remote sensing images by incorporating small-scale hyperspectral remote sensing images is an alternative way to generate remote sensing images with both large spatial range and high spectral resolution. This paper proposes an improved spectral resolution enhancement method (ISREM) using spectral matrix and weighting the spectral angle of the transformation matrix. ISREM is tested in a typical area of the Three-River Headwaters region (TRHR) to produce a synthetic hyperspectral image (HSI). Two existing spectral resolution enhancement methods, the color resolution improvement software package (CRISP) and spectral resolution enhancement method (SREM), are adopted to compare with ISREM. To further test the practicality of the synthetic HSIs generated by the ISREM, CRISP and SREM, they are used to estimate the coverage of native plant species (NPS) using support vector machines (SVM) and random forest (RF) regressions. The experimental results are as follows. (1) For the Pearson correlation coefficient between the synthetic HSI and original image, ISREM yielded the largest value of 0.9582, followed by CRISP and SREM with values of 0.9480 and 0.9514. For spectral similarity, the HSI generated by the ISREM was the closest to the original reference HSI in the spectral curve. It also showed the best cumulative performance with the use of the three quality evaluation indexes. (2) The identification accuracies of native plant species were 93.51%, 90.91%, 89.61% and 89.61% using generated HSIs and original multispectral image (MSI) within a threshold of 20%, respectively. Compared with original MSI, the synthetic HSI showed better ability to identify NPS in the study area, which further illustrated the effectiveness of the ISREM. (3) The ISREM can reduce the strict requirement of pure pixels and maintain the quality of synthetic HSI by spectral angle weighting. Hence, the proposed ISREM outperforms the existing CRISP and SREM methods in image spectral resolution enhancement of multispectral remote sensing images. [ABSTRACT FROM AUTHOR]

Using data from the Integrated Global Radiosonde Archive Version 2 (IGRA2) and the Multi Model Ensemble (MME) of four global climate models (GCMs), named CanESM5, IPSL-CM6A-LR, MIROC6, and MRI-ESM2-0, within the framework of phase 6 of the Coupled Model Intercomparison Project (CMIP6), we analyzed the changes in atmospheric total column water vapor (TCWV) over Central Asia in the future (2021–2100) under SSP-RCPs scenarios: SSP1-1.9, SSP1-2.6, SSP2-4.5, SSP3-7.0, SSP4-3.4, SSP4-6.0, and SSP5-8.5, relative to baseline period (1986–2005). Results showed that the annual mean TCWV from IGRA2 was consistent with the model output from 1979 to 2014 in Central Asia. Besides, the spatial distribution of TCWV in Central Asia during the baseline period was consistent between the models. The regional average value of Central Asia was between 10.8 mm and 12.4 mm, and decreased with elevation. TCWV will increase under different SSP-RCPs from 2021 to 2040, but showed different trends after 2040. It will increase under SSP1-1.9 and SSP1-2.6 scenarios from 2021 to 2050, and decrease after that. It will grow from 2021 to 2055 under SSP4-3.4 scenario, and then stay essentially constant. Under SSP2-4.5 and SSP4-6.0 scenarios, TCWV will rise rapidly during 2021–2065, but the growth will decline from 2065 to 2100. TCWV will continue to increase under SSP3-7.0 and SSP5-8.5 scenarios, and the largest increase is projected under SSP5-8.5 scenario. Change in near-surface temperature (Ts) matched the change in TCWV, but changes in precipitation and evapotranspiration are not significant during 2021–2100. In spite of the large variations in TCWV under different SSP-RCPs, the dominant characteristic in all scenarios shows that a large TCWV increase is demonstrated over areas with small TCWV amounts during the baseline period. On the contrary, increases will be small where the TCWV amounts had been large during the baseline period. The change in TCWV is highly correlated to the increase in Ts in Central Asia. Under SSP2-4.5, SSP3-7.0, SSP4-3.4, SSP4-6.0, and SSP5-8.5 scenarios, the higher the temperature due to higher radiative forcing, the steeper the regression slope between TCWV and Ts change. It is closest to the theoretical value of the Clausius-Clapeyron equation under SSP3-7.0 and SSP5-8.5 scenarios, but not presented under other scenarios. Spatially, steeper regression slopes during 2021–2100 have been found around the Caspian Sea in the southwest and in the high-elevation areas in the southeast of Central Asia, which is likely related to the abundant local water supply for evaporation. [ABSTRACT FROM AUTHOR]

The abundant and widespread unicellular cyanobacteria Synechococcus plays an important role in contributing to global phytoplankton primary production. In the present study, two novel cyanomyoviruses, S-N03 and S-H34 that infected Synechococcus MW02, were isolated from the coastal waters of the Yellow Sea. S-N03 contained a 167,069-bp genome comprising double-stranded DNA with a G + C content of 50.1%, 247 potential open reading frames and 1 tRNA; S-H34 contained a 167,040-bp genome with a G + C content of 50.1%, 246 potential open reading frames and 5 tRNAs. These two cyanophages contain fewer auxiliary metabolic genes (AMGs) than other previously isolated cyanophages. S-H34 in particular, is currently the only known cyanomyovirus that does not contain any AMGs related to photosynthesis. The absence of such common AMGs in S-N03 and S-H34, their distinct evolutionary history and ecological features imply that the energy for phage production might be obtained from other sources rather than being strictly dependent on the maintenance of photochemical ATP under high light. Phylogenetic analysis showed that the two isolated cyanophages clustered together and had a close relationship with two other cyanophages of low AMG content. Comparative genomic analysis, habitats and hosts across 81 representative cyanomyovirus showed that cyanomyovirus with less AMGs content all belonged to Synechococcus phages isolated from eutrophic waters. The relatively small genome size and high G + C content may also relate to the lower AMG content, as suggested by the significant correlation between the number of AMGs and G + C%. Therefore, the lower content of AMG in S-N03 and S-H34 might be a result of viral evolution that was likely shaped by habitat, host, and their genomic context. The genomic content of AMGs in cyanophages may have adaptive significance and provide clues to their evolution. [ABSTRACT FROM AUTHOR]

In this study, an existing combination approach that maximizes temporal correlations is used to combine six passive microwave satellite soil moisture products from 1998 to 2015 to assess its added value in long-term applications. Five of the products used are included in existing merging schemes such as the European Space Agency's essential climate variable soil moisture (ECV) program. These include the Special Sensor Microwave Imagers (SSM/I), the Tropical Rainfall Measuring Mission (TRMM/TMI), the Advanced Microwave Scanning Radiometer-Earth Observing System (AMSR-E) sensor on the National Aeronautics and Space Administration's (NASA) Aqua satellite, the WindSAT radiometer, onboard the Coriolis satellite and the soil moisture retrievals from the Advanced Microwave Scanning Radiometer 2 (AMSR2) sensor onboard the Global Change Observation Mission on Water (GCOM-W). The sixth, the microwave radiometer imager (MWRI) onboard China's Fengyun-3B (FY3B) satellite, is absent in the ECV scheme. Here, the normalized soil moisture products are merged based on their availability within the study period. Evaluation of the merged product demonstrated that the correlations and unbiased root mean square differences were improved over the whole period. Compared to ECV, the merged product from this scheme performed better over dense and sparsely vegetated regions. Additionally, the trends in the parent inputs are preserved in the merged data. Further analysis of FY3B's contribution to the merging scheme showed that it is as dependable as the widely used AMSR2, as it contributed significantly to the improvements in the merged product. [ABSTRACT FROM AUTHOR]

The shared socioeconomic pathways (SSPs) were designed to project future socioeconomic developments as they might unfold in the absence of explicit additional policies and measures to limit climate forcing or to enhance adaptive capacity. Based on the sixth national population census and the third economic census data of China in 2010, this paper projects the population and economic conditions of the Yangtze River basin from 2010 to 2100 under the SSPs. The results showed that: (1) the population growth rate in most areas of the Yangtze River basin will decrease from 2021 to 2100. The population of the eastern Sichuan Province will decrease obviously, while it will increase obviously in Shanghai during this period. The population of the Yangtze River basin will decline from 2010 to 2100 under the SSPs except for SSP3; (2) The GDP (Gross Domestic Product) in most regions will increase by more than CNY 30 billion (Chinese Yuan) compared with 2010 and the total GDP will continue to rise after 2020; (3) The population of the three major urban agglomerations will decrease from 2020 to 2100. However, the GDP of the three major urban agglomerations will increase year by year, among which the YRDUA (Yangtze River Delta Urban Agglomeration) has obvious economic advantages. The GDP growth rate will maintain above 6% in 2020 under different SSPs, and then the growth rate will slow down or stall, even with negative growth in SSP1 and SSP4; (4) The GDP Per of the Yangtze River basin shows growth under different SSPs and it will maintain a growth rate of 6–9% until 2020. While the average annual growth rate of the SSP5 will be about 2.56% at the end of the 21st century, and it will remain at about 1% under other scenarios. This paper provides a scientific basis for the study of future population and socioeconomic changes and climate predictions for quantifying disaster risks. [ABSTRACT FROM AUTHOR]

Very high-resolution remote sensing change detection has always been an important research issue due to the registration error, robustness of the method, and monitoring accuracy, etc. This paper proposes a robust and more accurate approach of change detection (CD), and it is applied on a smaller experimental area, and then extended to a wider range. A feature space, including object features, Visual Geometry Group (VGG) depth features, and texture features, is constructed. The difference image is obtained by considering the contextual information in a radius scalable circular. This is to overcome the registration error caused by the rotation and shift of the instantaneous field of view and also to improve the reliability and robustness of the CD. To enhance the robustness of the U-Net model, the training dataset is constructed manually via various operations, such as blurring the image, increasing noise, and rotating the image. After this, the trained model is used to predict the experimental areas, which achieved 92.3% accuracy. The proposed method is compared with Support Vector Machine (SVM) and Siamese Network, and the check error rate dropped to 7.86%, while the Kappa increased to 0.8254. The results revealed that our method outperforms SVM and Siamese Network. [ABSTRACT FROM AUTHOR]

Trap-controlled mechanoluminescent (ML) materials characterized by reproducible mechanoluminescence (ML) after irradiation recharging have shown attractive prospects in applications including stress distribution visualization, stress-driven light sources, and anti-counterfeiting. However, these materials generally suffer from the difficulty of achieving non-decaying ML when subjected to continuous mechanical stimulation. Herein, we develop a trap-controlled reproducible ML material, Li2MgGeO4:Mn2+, and report its short-term non-decaying ML behavior. Investigation of trap properties suggests that the unique non-decaying ML behavior should arise from the deep traps existing in Li2MgGeO4:Mn2+, which provide electron replenishment for shallow traps that release small numbers of electrons during short-term cyclic friction. Our results are expected to provide a reference for the ultimate achievement of long-term non-decaying ML in such materials. [ABSTRACT FROM AUTHOR]

The application of groundwater relief, i.e., dewatering, ascending wells, drilled upward from the mining tunnel into the overlying aquifer, is common in underground mining engineering. In this study, the seepage characteristics of single ascending partially and fully penetrating relief wells are investigated using a series of laboratory sand-tank experiments and numerical simulations. The seepage characteristics of ascending wells dewatering an overlying aquifer are different from those of conventional pumping wells descending from the ground surface into the underlying aquifer, because of the pronounced influence of the seepage face boundary condition along the seepage boundary of the ascending dewatering well. The seepage face of the ascending well is formed as the well casing remains open and water is discharged under the action of gravity through the well casing. The results of laboratory sand-tank experiments and modeling show that when the degree of penetration of an ascending relief well does not exceed a critical value, the effect of the seepage face cannot be ignored. In particular, the seepage flux increases as the degree of penetration increases following an exponential function, and the relationship between the seepage flux and the well radius can be described using a power law function. The results of numerical simulations are used to develop a series of type curves to evaluate the effects of the critical degree of penetration for different well radii and different aquifer water levels. Modified versions of the Dupuit and Dupuit–Thiem formulae for a single ascending partially well for the degree of penetration less than the critical one for the unconfined, confined, and confined-unconfined aquifers are developed. [ABSTRACT FROM AUTHOR]

Many life activities and key functions in organisms are maintained by different types of protein–protein interactions (PPIs). In order to accelerate the discovery of PPIs for different species, many computational methods have been developed. Unfortunately, even though computational methods are constantly evolving, efficient methods for predicting PPIs from protein sequence information have not been found for many years due to limiting factors including both methodology and technology. Inspired by the similarity of biological sequences and languages, developing a biological language processing technology may provide a brand new theoretical perspective and feasible method for the study of biological sequences. In this paper, a pure biological language processing model is proposed for predicting protein–protein interactions only using a protein sequence. The model was constructed based on a feature representation method for biological sequences called bio-to-vector (Bio2Vec) and a convolution neural network (CNN). The Bio2Vec obtains protein sequence features by using a "bio-word" segmentation system and a word representation model used for learning the distributed representation for each "bio-word". The Bio2Vec supplies a frame that allows researchers to consider the context information and implicit semantic information of a bio sequence. A remarkable improvement in PPIs prediction performance has been observed by using the proposed model compared with state-of-the-art methods. The presentation of this approach marks the start of "bio language processing technology," which could cause a technological revolution and could be applied to improve the quality of predictions in other problems. [ABSTRACT FROM AUTHOR]

Low flow is a seasonal phenomenon which is a critical requirement for utilization of water resources under rapidly changing environmental conditions. The operation of the Three Gorges Dam (TGD) has had a great influence on downstream low flow in the Yangtze River. In this paper, the characteristics of low flow in the main Yangtze River were analyzed during the dry season before and after the TGD operation during the period of 1956–2016. The results show that: (1) the operation of the TGD has changed the spatial and temporal distribution of streamflow in the middle and lower Yangtze River and the annual mean low flow has increased significantly since the TGD operation. (2) The operation of the TGD could advance the date of the start of dry season in the lower Yangtze River basin. The start dates of the dry season in the Yichang, Hankou and Datong stations were advanced by 14 days, 10 days and 9 days, respectively. (3) The minimum streamflow in the lower Yangtze River has increased notably since the TGD operation. The minimum streamflow was raised by 42.91%, 13.76% and 6.06% at the Yichang, Hankou and Datong stations, respectively. The increasing number of dams in the world might have the potential effects on downstream low flow. More attention should be paid to investigating the influence of dam construction on low flow in rivers all over the world. [ABSTRACT FROM AUTHOR]

The strawberry vein banding virus (SVBV) open reading frame (ORF) VI encodes a P6 protein known as the RNA silencing suppressor. This protein is known to form inclusion like granules of various sizes and accumulate in both the nuclei and the cytoplasm of SVBV-infected plant cells. In this study, we have determined that the P6 protein is the only trans-activator (TAV) encoded by SVBV, and can efficiently trans-activate the translation of downstream gfp mRNA in a bicistron derived from the SVBV. Furthermore, the P6 protein can trans-activate the expression of different bicistrons expressed by different caulimovirus promoters. The P6 protein encoded by SVBV from an infectious clone can also trans-activate the expression of bicistron. Through protein-protein interaction assays, we determined that the P6 protein could interact with the cell translation initiation factor FveIF3g of Fragaria vesca and co-localize with it in the nuclei of Nicotiana benthamiana cells. This interaction reduced the formation of P6 granules in cells and its trans-activation activity on translation. [ABSTRACT FROM AUTHOR]

With the widespread attention on clean energy use and energy efficiency, the integrated energy system (IES) has received considerable research and development. This paper proposed an electricity-gas IES optimization planning model based on a coupled combined cooling heating and power system (CCHP). The planning and operation of power lines and gas pipelines are considered. Regarding CCHP as the coupled hub of an electricity-gas system, the proposed model minimizes total cost in IES, with multistage planning and multi-scene analyzing. Renewable energy generation is also considered, including wind power generation and photovoltaic power generation. The numerical results reveal the replacing and adding schemes of power lines and gas pipelines, the optimal location and capacity of CCHP. In comparison with conventional separation production (SP), the optimization model which regards CCHP as the coupled hub attains better economy. At the same time, the influence of electricity price and natural gas price on the quantities of purchasing electricity and purchasing gas in the CCHP system is analyzed. According to the simulation result, a benchmark gas price is proposed, which shows whether the CCHP system chooses power generation. The model results and discussion demonstrate the validity of the model. [ABSTRACT FROM AUTHOR]

This paper proposes a novel adaptive consensus algorithm (ACA) for distributed heat-electricity energy management (HEEM) of an islanded microgrid. In order to simultaneously satisfy the heat-electricity energy balance constraints, ACA is implemented with a switch between unified consensus and independent consensus according to the dynamic energy mismatches. The feasible operation region of a combined heat and power (CHP) unit is decomposed into eight searching sub-regions, thus its electricity and heat energy outputs can simultaneously match the incremental cost consensus requirement and the heat-electricity energy balance constraints. Case studies are thoroughly carried out to verify the performance of ACA for distributed HEEM of an islanded microgrid. [ABSTRACT FROM AUTHOR]

In recent years, Hydro-pneumatic cycling compressed air energy storage (HC-CAES) has become an important topic in compressed air energy storage (CAES) technology research. In HC-CAES, air is compressed by liquid and driven by electrical equipment when energy is stored, and then, liquid is used to drive the water conservancy equipment to generate electricity. In this study, adaptive hydraulic potential energy transfer technology is proposed to solve a series of problems in the HC-CAES system, including the high fluctuation range of gas potential energy, poor operating stability, low efficiency, and so on. Therefore, fluctuating potential energy can be stably transferred through the variable area hydraulic devices, which can be controlled with an on–off valve. The structure and operation scheme of the adaptive hydraulic potential energy transfer device used in the HC-CAES system are explained in detail; the device can provide a stable water head range for the highly efficient operation of water conservancy equipment. Moreover, an optimal operation scheme was determined through simulation analysis; a physical experiment platform was built to verify the feasibility of the design and stability of system operation. [ABSTRACT FROM AUTHOR]

An assessment of the impact of climate change on regional hydrological processes is vital for effective water resources management and planning. This study investigated the potential effects of climate change on water availability, seasonal runoff, flooding, and water stress in the Yellow River and Pearl River basins in China over the next 30 years, using a semi-distributed hydrological model based on a combination of five general circulation models with four Representative Concentration Pathway scenarios and five Shared Socioeconomic Pathways. The results indicated annual mean temperature could rise higher in the Yellow River Basin than the Xijiang River Basin during 2021–2050. Higher risks of small floods and some big floods, but lower risks of rare big floods are projected for both basins. Water scarcity will continually threaten the Yellow River Basin, especially during the dry season and around 2025. In comparison with the effects of climate change, population variation was expected to have a greater impact on water scarcity. A longer and drier dry season is projected for the Pearl River Basin, which could aggravate water stress and saltwater intrusion into the Pearl River delta. Although the present findings have implications for water resource management planning, caution should be observed because of the neglect of reservoir/dam operations and inherent projection uncertainty. [ABSTRACT FROM AUTHOR]

Southern tomato amalgavirus (STV) is a cryptic pathogen that is abundant in tomato production fields and intensifies the resurgence of tomato yellow stunt disease (ToYSD), together with other phytoviruses. Here, we mapped the geographical and genomic diversity, phylogenetics, and evolutionary dynamics of STV. We found that STV prevailed across China and Pakistan, with a maximum average rate of infection of 43.19% in Beijing, China, and 40.08% in Punjab, Pakistan. Subsequently, we amplified, cloned, and annotated the complete genome sequences of STV isolates from Solanum lycopersicum L. in China (OP548653 and OP548652) and Pakistan (MT066231) using Sanger and next-generation sequencing (NGS). These STV isolates displayed close evolutionary relationships with others from Asia, America, and Europe. Whole-genome-based molecular diversity analysis showed that STV populations had 33 haplotypes with a gene diversity (Hd) of 0.977 and a nucleotide diversity (π) of 0.00404. The genetic variability of RNA-dependent RNA-polymerase (RdRp) was higher than that of the putative coat protein (CP) p42. Further analysis revealed that STV isolates were likely to be recombinant but with a lower-to-moderate level of confidence. With a variable distribution pattern of positively and negatively selected sites, negative selection pressure predominantly acted on p42 and RdRp. These findings elaborated on the molecular variability and evolutionary trends among STV populations across major tomato-producing regions of the world.

Polygonatum cyrtonema rhizome (PCR), the dried sweet rhizome of Polygonatum cyrtonema Hua, is commonly used as a tonic remedy and a functional food in Asia, Europe, and North America. Multiple components, including secondary metabolites, monosaccharides, oligosaccharides, and polysaccharides, collectively contribute to the therapeutic effects of PCR. Processing time exerts a significant influence on the quality of PCR, but the various processing stages have not been comprehensively chemically profiled. It is urgent to study processing-induced chemical variations in PCR to control the processing degree. In this study, multiple chromatographic and mass spectrometric techniques were used in combination with multivariate statistical analysis to perform qualitative and quantitative research on secondary metabolites and carbohydrates in PCR during processing. The results demonstrated that PCR processing can be divided into three stages, namely the raw stage (0 h), the middle stage (1-6 h), and the late stage (8-18 h). Twenty differential compounds were screened from secondary metabolites and oligosaccharides to distinguish PCR in different processing stages. Furthermore, the chemical variations of Polygonatum cyrtonema polysaccharides (PCP) also entered a new stage after processing for 6 h. Multiple chemical mechanisms, including hydrolysis, oxidative decomposition, dehydration, Maillard reaction, and polymerization were involved in the processing. This work provides a scientific basis to reveal the relationship between processing stage and chemical variations.

Many life activities and key functions in organisms are maintained by different types of protein⁻protein interactions (PPIs). In order to accelerate the discovery of PPIs for different species, many computational methods have been developed. Unfortunately, even though computational methods are constantly evolving, efficient methods for predicting PPIs from protein sequence information have not been found for many years due to limiting factors including both methodology and technology. Inspired by the similarity of biological sequences and languages, developing a biological language processing technology may provide a brand new theoretical perspective and feasible method for the study of biological sequences. In this paper, a pure biological language processing model is proposed for predicting protein⁻protein interactions only using a protein sequence. The model was constructed based on a feature representation method for biological sequences called bio-to-vector (Bio2Vec) and a convolution neural network (CNN). The Bio2Vec obtains protein sequence features by using a "bio-word" segmentation system and a word representation model used for learning the distributed representation for each "bio-word". The Bio2Vec supplies a frame that allows researchers to consider the context information and implicit semantic information of a bio sequence. A remarkable improvement in PPIs prediction performance has been observed by using the proposed model compared with state-of-the-art methods. The presentation of this approach marks the start of "bio language processing technology," which could cause a technological revolution and could be applied to improve the quality of predictions in other problems.