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The article looks into the nature of the social bond shared by identical twins. Topics discussed include a study on the hidden features of the twin bond, the author's view on a partial genetic basis for being attracted to some features of an object or situation that makes it likely for close relatives to favor one choice or strategy over another, and factor that draws partners together and keeps them close.

A 38-year-old woman with lymphocytic hypophysitis experienced a lack of efficacy during treatment with levothyroxine-sodium and hydrocortisone. She presented with symptoms such as headache, peripheral vision alterations, and blurred vision after giving birth to twin boys. Further examination revealed a pituitary mass and a diagnosis of lymphocytic hypophysitis. Despite receiving hydrocortisone and levothyroxine-sodium, her anterior pituitary function did not normalize, and she required ongoing treatment for hypopituitarism. This suggests that the hydrocortisone and levothyroxine-sodium were not effective in treating her condition. [Extracted from the article]

This article discusses two case reports of children with X-linked agammaglobulinaemia who exhibited lack of efficacy during treatment with azithromycin or naproxen for Campylobacter jejuni or Campylobacter reactive arthritis and erythema nodosum. In the first case, a 3-year-old boy experienced persistent symptoms despite receiving azithromycin, and his treatment was changed to triple drug therapy before complete resolution of symptoms was achieved after 12 months. In the second case, a 3.5-year-old boy also had persistent symptoms despite receiving azithromycin and naproxen, and his treatment was similarly changed to triple drug therapy before complete resolution of symptoms was achieved after 12 months. [Extracted from the article]

Author InformationAn event is serious (based on the ICH definition) when the patient outcome is:• * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important eventIn a case series, two men, aged 27-45 years were described, who developed hepatocellular Jaundic during treatment with caffeine/coffea for weight loss [route, dosage and duration of treatment to reaction onset not stated]. [Extracted from the article]