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Unmanned aerial vehicle-based LiDAR survey provides very-high-density point clouds, which involve very rich information about forest detailed structure, allowing for detection of individual trees, as well as demanding high computational load. Single-tree detection is of great interest for forest management and ecology purposes, and the task is relatively well solved for forests made of single or largely dominant species, and trees having a very evident pointed shape in the upper part of the canopy (in particular conifers). Most authors proposed methods based totally or partially on search of local maxima in the canopy, which has poor performance for species that have flat or irregular upper canopy, and for mixed forests, especially where taller trees hide smaller ones. Such considerations apply in particular to Mediterranean hardwood forests. In such context, it is imperative to use the whole volume of the point cloud, however keeping computational load tractable. The authors propose the use of a methodology based on modelling the 3D-shape of the tree, which improves performance with respect to maxima-based models. A case study, performed on a hazel grove, is provided to document performance improvement on a relatively simple, but significant, case. [ABSTRACT FROM AUTHOR]

Nutrition has a coadjuvant role in the management of children with acute diseases. We aimed to examine nutritional status, macronutrient requirements and actual macronutrient delivery in bronchiolitis. The nutritional status was classified according to WHO criteria and resting energy expenditure (MREE) was measured using an indirect calorimeter. Bland–Altman analysis was used to examine the agreement between MREE and estimated energy expenditure (EEE) with standard equations. Based on the ratio MREE/EEE in relation to Schofield equation on admission, we defined the subjects’ metabolic status. A total of 35 patients were enrolled and 46% were malnourished on admission, and 25.8% were hypermetabolic, 37.1% hypometabolic and 37.1% normometabolic. We performed a 24-h recall in 10 children and 80% were overfed (AEI: MREE >120%). Mean bias (limits of agreement) with MREE was 8.9 (−73.9 to 91.8%) for Schofield; 61.0 (−41 to 163%) for Harris–Benedict; and 9.9 (−74.4 to 94.2%) for FAO-WHO equation. Metabolism of infants with bronchiolitis is not accurately estimated by equations. [ABSTRACT FROM PUBLISHER]

Oxygen and nitrogen radicals are frequently produced during viral infections. These radicals are not only a physiological mechanism for pathogen clearance but also result in many pathological consequences. Low concentrations of radicals can promote viral replication; however, high concentrations of radicals can also inhibit viral replication and are detrimental to the cell due to their mitogenic activity. We reviewed the detailed mechanisms behind oxygen and nitrogen radical production and focused on how viruses induce radical production. In addition, we examined the eff ects of oxygen and nitrogen radicals on both the virus and host. We also reviewed enzymatic and chemical detoxifi cation mechanisms and recent advances in therapeutic antioxidant applications. Many molecules that modulate the redox balance have yielded promising results in cell and animal models of infection. This encourages their use in clinical practice either alone or with existing therapies. However, since the redox balance also plays an important role in host defence against pathogens, carefully designed clinical trials are needed to assess the therapeutic benefi ts and secondary eff ects of these molecules and whether these eff ects diff er between diff erent types of viral infections. [ABSTRACT FROM AUTHOR]