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Your search keyword '"Esposito, S."' showing total 4 results
4 results on '"Esposito, S."'

1. Peri-Operative Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Cardiac and Thoracic Surgery

Author

Bianchini S., Nicoletti L., Monaco S., Rigotti E., Corbelli A., Colombari A., Auriti C., Caminiti C., Conti G., De Luca M., Dona D., Galli L., Garazzino S., Inserra A., La Grutta S., Lancella L., Lima M., Lo Vecchio A., Pelizzo G., Petrosillo N., Piacentini G., Pietrasanta C., Principi N., Puntoni M., Simonini A., Tesoro S., Venturini E., Staiano A., Caramelli F., Gargiulo G.D., and Esposito S.

Subjects
surgical antibiotic prophylaxis, ECMO, thoracic surgery, cardiac surgery, pediatric infectious diseases, antibiotics
Abstract

Surgical site infections (SSIs) represent a potential complication of surgical procedures, with a significant impact on mortality, morbidity, and healthcare costs. Patients undergoing cardiac surgery and thoracic surgery are often considered patients at high risk of developing SSIs. This consensus document aims to provide information on the management of peri-operative antibiotic prophylaxis for the pediatric and neonatal population undergoing cardiac and non-cardiac thoracic surgery. The following scenarios were considered: (1) cardiac surgery for the correction of congenital heart disease and/or valve surgery; (2) cardiac catheterization without the placement of prosthetic material; (3) cardiac catheterization with the placement of prosthetic material; (4) implantable cardiac defibrillator or epicardial pacemaker placement; (5) patients undergoing ExtraCorporal Membrane Oxygenation; (6) cardiac tumors and heart transplantation; (7) non-cardiac thoracic surgery with tho-racotomy; (8) non-cardiac thoracic surgery using video-assisted thoracoscopy; (9) elective chest drain placement in the pediatric patient; (10) elective chest drain placement in the newborn; (11) thoracic drain placement in the trauma setting. This consensus provides clear and shared indications, repre-senting the most complete and up-to-date collection of practice recommendations in pediatric cardiac and thoracic surgery, in order to guide physicians in the management of the patient, standardizing approaches and avoiding the abuse and misuse of antibiotics.

Published
2022

2. Ultrastructural Pathology of Pediatric Myocardium in Acute Ischemia: Bioptic Study Before and After Treatment with Cardioplegic Solution.

Author

Cuccurullo, L., Accardo, M., Agozzino, L., Blasi, F., Esposito, S., and Vosa, C.

Subjects
CORONARY heart disease in children, CARDIAC surgery, MYOCARDIUM physiology, SOLUTIONS (Pharmacy), DRUG efficacy, HEART biopsy, HEART cells, SARCOPLASM
Abstract

Protecting the myocardium from the risk of acute ischemia during heart surgery is still an unsolved problem; the problem is even more open and more pressing in pediatric heart surgery. To meet this greater risk it is advisable to use a cardioplegic solution with a composition that is better suited to the particular morphofunctional conditions of the myocardium in the child, i.e., a solution offering greater protection. To this purpose the authors experimented with Celsior cardioplegic solution during heart surgery in children to evaluate the efficacy compared to the standard St. Thomas solution. In this comparative study 15 children were treated with Celsior cardioplegic solution and 15 others with St. Thomas cardioplegic solution. Each patient underwent 2 biopsies of the myocardium, the first before cardioplegic treatment and the second immediately after reperfusion.In both groups, focal lesions involving both the cardiomyocytes and the vascular-stromal structures were randomly found. The former had undergone a necrotic-regressive process with changes in the myofibrils and the mitochondria. The vascular–stromal structures showed changes in the permeability of the capillary endothelia, with interstitial edema. The results show the lesions to be similar in the 2 groups both on a quality and quantitative level. [ABSTRACT FROM AUTHOR]

Published
2006
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3. Hepatic cryptococcosis in a heart transplant recipient.

Author

Utili, R., Tripodi, M. F., Ragone, E., Casillo, R., Pasquale, G., De Santo, L., and Esposito, S.

Subjects
CRYPTOCOCCOSIS, CARDIAC surgery, HEART transplantation, HEART transplant recipients, TOMOGRAPHY, DYSPNEA
Abstract

Cryptococcosis primarily occurs in patients with impaired immune response. While pulmonary and/or cerebral involvement are more often described, there is limited experience of its presence in other sites. We present a case of hepatic cryptococcosis with possible pulmonary involvement in a 54-year-old male heart transplant recipient. Two months after heart transplantation, he developed a persistent, moderate dyspnea with fever and signs of liver damage. Diagnosis was made with liver biopsy for a concurrent reactivation of chronic hepatitis B virus (HBV) infection already present before transplant. Along with a mild chronic HBV hepatitis with fibrosis, we observed sinusoidal dilation and groups of bright, rounded, colorless cells with a central nucleus suggestive of cryptococci. Periodic acid–Schiff stain clearly showed encapsulated yeasts, which supported the diagnosis. Cryptococcal antigen was positive in serum and negative in the cerebrospinal fluid. Computed tomography scan of the chest demonstrated a mild interstitial infiltrate. The patient promptly responded to reduction of immunosuppressive therapy and antifungal treatment with amphotericin B lipid complex and flucytosine followed by maintenance treatment with fluconazole. Cryptococcosis should always be considered in the differential diagnosis in immunocompromised hosts with dyspnea and signs of extrapulmonary involvement. Diagnosis of extrapulmonary and extraneural cryptococcosis is difficult and often fortuitous; a histopathological examination of tissues involved is probably warranted. [ABSTRACT FROM AUTHOR]

Published
2004
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4. Peri-Operative Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Cardiac and Thoracic Surgery: A RAND/UCLA Appropriateness Method Consensus Study

Author

Sonia, Bianchini, Laura, Nicoletti, Sara, Monaco, Erika, Rigotti, Agnese, Corbelli, Annamaria, Colombari, Cinzia, Auriti, Caterina, Caminiti, Giorgio, Conti, Maia, De Luca, Daniele, Donà, Luisa, Galli, Silvia, Garazzino, Alessandro, Inserra, Stefania, La Grutta, Laura, Lancella, Mario, Lima, Andrea, Lo Vecchio, Gloria, Pelizzo, Nicola, Petrosillo, Giorgio, Piacentini, Carlo, Pietrasanta, Nicola, Principi, Matteo, Puntoni, Alessandro, Simonini, Simonetta, Tesoro, Elisabetta, Venturini, Annamaria, Staiano, Fabio, Caramelli, Gaetano Domenico, Gargiulo, Susanna, Esposito, On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group, Bianchini, Sonia, Nicoletti, Laura, Monaco, Sara, Rigotti, Erika, Corbelli, Agnese, Colombari, Annamaria, Auriti, Cinzia, Caminiti, Caterina, Conti, Giorgio, De Luca, Maia, Donà, Daniele, Galli, Luisa, Garazzino, Silvia, Inserra, Alessandro, La Grutta, Stefania, Lancella, Laura, Lima, Mario, Lo Vecchio, Andrea, Pelizzo, Gloria, Petrosillo, Nicola, Piacentini, Giorgio, Pietrasanta, Carlo, Principi, Nicola, Puntoni, Matteo, Simonini, Alessandro, Tesoro, Simonetta, Venturini, Elisabetta, Staiano, Annamaria, Caramelli, Fabio, Gargiulo, Gaetano, Esposito, Susanna, Bianchini, S., Nicoletti, L., Monaco, S., Rigotti, E., Corbelli, A., Colombari, A., Auriti, C., Caminiti, C., Conti, G., De Luca, M., Dona, D., Galli, L., Garazzino, S., Inserra, A., La Grutta, S., Lancella, L., Lima, M., Lo Vecchio, A., Pelizzo, G., Petrosillo, N., Piacentini, G., Pietrasanta, C., Principi, N., Puntoni, M., Simonini, A., Tesoro, S., Venturini, E., Staiano, A., Caramelli, F., Gargiulo, G. D., and Esposito, S.

Subjects
Settore MED/38 - Pediatria Generale e Specialistica, Microbiology (medical), Biochemistry, Microbiology, thoracic surgery, antibiotics, pediatric infectious disease, Infectious Diseases, surgical antibiotic prophylaxis, antibiotic, Settore MED/41 - ANESTESIOLOGIA, surgical antibiotic prophylaxi, Pharmacology (medical), cardiac surgery, ECMO, pediatric infectious diseases, General Pharmacology, Toxicology and Pharmaceutics, Keywords: antibiotic
Abstract

Surgical site infections (SSIs) represent a potential complication of surgical procedures, with a significant impact on mortality, morbidity, and healthcare costs. Patients undergoing cardiac surgery and thoracic surgery are often considered patients at high risk of developing SSIs. This consensus document aims to provide information on the management of peri-operative antibiotic prophylaxis for the pediatric and neonatal population undergoing cardiac and non-cardiac thoracic surgery. The following scenarios were considered: (1) cardiac surgery for the correction of congenital heart disease and/or valve surgery; (2) cardiac catheterization without the placement of prosthetic material; (3) cardiac catheterization with the placement of prosthetic material; (4) implantable cardiac defibrillator or epicardial pacemaker placement; (5) patients undergoing ExtraCorporal Membrane Oxygenation; (6) cardiac tumors and heart transplantation; (7) non-cardiac thoracic surgery with thoracotomy; (8) non-cardiac thoracic surgery using video-assisted thoracoscopy; (9) elective chest drain placement in the pediatric patient; (10) elective chest drain placement in the newborn; (11) thoracic drain placement in the trauma setting. This consensus provides clear and shared indications, representing the most complete and up-to-date collection of practice recommendations in pediatric cardiac and thoracic surgery, in order to guide physicians in the management of the patient, standardizing approaches and avoiding the abuse and misuse of antibiotics.

Published
2022

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