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Start Over Author "Williams ED" Language dutch; flemish
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1. [Type II multiple endocrine neoplasms (MEN IIB): an unusual cause of constipation. A plea for early thyroidectomy].

Author

Post ED, Wauters EA, Huber J, Williams ED, and Lips CJ

Subjects
Child, Preschool, Female, Humans, Thyroid Neoplasms surgery, Thyroidectomy, Constipation etiology, Multiple Endocrine Neoplasia complications, Thyroid Neoplasms pathology
Abstract

We present a 5 year old girl who was diagnosed to have multiple endocrine neoplasia syndrome type IIB (MEN IIB). She presented with serious constipation and had the distinct features of MEN IIB. 100% of the patients with MEN IIB develop medullary thyreoïd carcinoma (MTC). MTC in MEN IIB is known to behave in a very aggressive way. Microscopically MTC was already present in this patient despite of normal calcitonin stimulation tests. Accordingly we plead for a more radical management relating to thyreoïdectomy in MEN IIB.

Published
1993

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