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Oudere volwassenen lopen meer risico op bijwerkingen van medicatie. Voornamelijk anticholinerge bijwerkingen kunnen leiden tot centrale en perifere bijwerkingen op somatisch en cognitief vlak. In dit pilootonderzoek hebben we de anticholinerge lading van de medicatieschema’s van 75 bewoners van een woonzorgcentrum bepaald aan de hand van twee gevalideerde meetschalen, nl. de Anticholinergic Cognitive Burden Scale (ACB) en de Drug Burden Index (DBI) Tevens bekeken we in welke mate de verschillende klasse(n) van medicijnen deze anticholinerge lading beïnvloeden. Tenslotte hebben we de samenhang van een hoge anticholinerge lading met incidenten (urineweginfecties, vallen, delier) geanalyseerd. We zien een hoge mate van polymedicatie en gebruik van psychofarmaca met een anticholinerge werking; de gemiddelde score bedraagt 1,67 op de ACB en 0,87 op de DBI. De anticholinerge lading wordt in de ACB voornamelijk bepaald door antipsychotica (t = 6,110, p < 0,001), bij de DBI zien we een invloed van alle medicatie met anticholinerge eigenschappen (F = 6,764, p < 0.001). Een risicoscore op de DBI heeft een statistisch significante samenhang met het doormaken van een urineweginfectie (F = 5,877, p = 0,018). Deze invloed blijft significant na het corrigeren voor covariaten. De anticholinerge lading van medicatieschema’s bij residenten is hoog. Tevens hangt een verhoogde anticholinerge lading samen met het doormaken van urineweginfectie. Het verlagen van de anticholinerge lading binnen woonzorgcentra vormt dan ook een belangrijke uitdaging naar de toekomst toe.

Psychotische depressie is een veelvoorkomende, ernstige psychiatrische aandoening bij gehospitaliseerde depressieve ouderen van 60 jaar en ouder. Ouderen met een psychotische depressie vertonen specifieke symptomen die verschillen van die bij jongere volwassenen met een psychotische depressie. Daarenboven zijn de symptomen ook anders dan deze die voorkomen bij ouderen met een depressieve stoornis zonder psychotische kenmerken. Als behandeling wordt een tricyclisch antidepressivum, al dan niet in combinatie met een antipsychoticum, of electroconvulsietherapie voorgesteld. Deze behandelingen kunnen echter belangrijke bijwerkingen met zich meebrengen waardoor intensieve begeleiding vereist is. In dit artikel geven we een overzicht van klinische aandachtspunten bij de diagnostiek en behandeling van psychotische depressie bij ouderen.

bespreking recent onderzoek J Vermeulen[1], JCL Neyens[1,2],MD Spreeuwenberg[ 1,2], E van Rossum[1,2], LP deWitte[1,2] 1 CAPHRI, Universiteit Maastricht, Department of Health Services Research, Maastricht. 2 Kenniskring Technologie in de Zorg, Zuyd Hogeschool Heerlen, Heerlen.

This paper analyses the tensions perceived in the political debate between the freedom of education and the status of publicly funded denominational schools in the Netherlands on the one hand and the limitations flowing from the principles of separation of church and state and state neutrality on the other. It is argued that public funding of these schools is not incompatible with these principles – attention is drawn to a recent law which ensures some structural funding of religious instruction even on public schools – and that there are no good reasons – perceived risks with regard to issues of quality, segregation, indoctrination – to put an end to such funding.

Dit artikel is geschreven ten behoeve van het NVSST symposium ‘to hear or not to hear’, 1 maart 2019. Met een cochleair implantaat (CI) worden de spraakperceptiemogelijkheden in rust van ernstig slechthorende en dove kinderen aanzienlijk verbeterd. In ongunstige luistersituaties zijn de hoormogelijkheden nog beperkt. De auditieve mogelijkheden met CI bieden in principe voldoende voorwaarde voor de verwerving van een leeftijdsadequaat woordbegrip. Echter op het gebied van complexere taalvaardigheden zoals morfo-syntaxis, vertelvaardigheden en verbaal redeneren worden nog problemen beschreven. Een mogelijke verklaring daarvoor, naast het verminderde spraakverstaan, is gelegen in de zwakkere en instabiele fonologische representaties. Er blijken vooral problemen met de storage component (fonologische loop) van het werkgeheugen. Dit heeft tot gevolg dat de capaciteit en de effectiviteit van het werkgeheugen verminderen.

The new pedestrian area has been one of the main urban projects designed for the centre of Brussels in recent decades. In 2015, the transit route in the city centre - Boulevard Anspach - was closed to traffic. The redevelopment of public space and the renovation of the main metro stations are now nearing completion. The finalisation of this urban project and the challenges it has faced are, by definition, complex. Experiences elsewhere in the country and abroad, as well as the data collected by BSI-BCO, show that it will have a significant impact at different levels: quality of public space, housing and facilities, local economy and employment, mobility, accessibility and logistics, social and cultural activities, etc. This synopsis is an update of a previously published work (no. 115). Part 1 sets out the general context of this project which has not been spared by several external crises (lockdown following the attacks in Paris, attacks in Brussels, the tunnel crisis and, of course, the covid crisis). Part 2 develops the challenges which remain. In conclusion, this synopsis proposes some concrete ways to improve the quality and management of the project.

The new pedestrian area has been one of the main urban projects designed for the centre of Brussels in recent decades. In 2015, the transit route in the city centre - Boulevard Anspach - was closed to traffic. The redevelopment of public space and the renovation of the main metro stations are now nearing completion. The finalisation of this urban project and the challenges it has faced are, by definition, complex. Experiences elsewhere in the country and abroad, as well as the data collected by BSI-BCO, show that it will have a significant impact at different levels: quality of public space, housing and facilities, local economy and employment, mobility, accessibility and logistics, social and cultural activities, etc. This synopsis is an update of a previously published work (no. 115). Part 1 sets out the general context of this project which has not been spared by several external crises (lockdown following the attacks in Paris, attacks in Brussels, the tunnel crisis and, of course, the covid crisis). Part 2 develops the challenges which remain. In conclusion, this synopsis proposes some concrete ways to improve the quality and management of the project.

The new pedestrian area has been one of the main urban projects designed for the centre of Brussels in recent decades. In 2015, the transit route in the city centre - Boulevard Anspach - was closed to traffic. The redevelopment of public space and the renovation of the main metro stations are now nearing completion. The finalisation of this urban project and the challenges it has faced are, by definition, complex. Experiences elsewhere in the country and abroad, as well as the data collected by BSI-BCO, show that it will have a significant impact at different levels: quality of public space, housing and facilities, local economy and employment, mobility, accessibility and logistics, social and cultural activities, etc. This synopsis is an update of a previously published work (no 115). Part 1 sets out the general context of this project which has not been spared by several external crises (lockdown following the attacks in Paris, attacks in Brussels, the tunnel crisis and, of course, the covid crisis). Part 2 develops the challenges which remain. In conclusion, this synopsis proposes some concrete ways to improve the quality and management of the project.

Call to a new-Copernican revolution: Scientific conclusions about sexuality. The debate on same-sex relationships in the Dutch Reformed Church (NGK) reached an all-time low with some calling gay people pedophiles. In the light of recent events it is clear that the church is deeply divided with regard to beliefs regarding sexuality: some still maintain that a deviation from heterosexuality is a sin and would be punished by God. This research does not aim to contribute to the hermeneutical debate and reinterpretation of the so-called gay texts in the Bible, but rather seeks to explore the scientific research on sexuality. It is stipulated that sexuality is determined in utero and that the person has no control over it and that varied sexualities are merely unique characteristics of human beings. It is further argued that the church cannot keep ignoring the sciences, as the Catholic church did with regard to heliocentrism, and that a neo-Copernican revolution is indeed at hand. Intradisciplinary/interdisciplinary implications: This article looks at sexuality from a biological perspective and reaches the conclusion that sexuality is determined in utero, before birth. This challenges the traditional perspective that any non-heteronormative sexuality is a choice and hence sin in the eyes of God. This scientific approach strengthens newer hermeneutical interpretations of the so-called anti-gay texts in the Bible. The fields involved are biology and sexual ethics through the lens of critical qualitative research. The field of the traditional hermeneutics of sexuality is briefly mentioned, but the author does not endeavour to contribute to this field, but rather present the biological research as a challenging force to the more traditional approach.

The new pedestrian area in the centre of Brussels is one of the most important urban projects of the last decades. In 2015, the central traffic artery, Boulevard Anspach, was pedestrianised. The public space and the biggest metro stations must still be renovated. The implementation of this project and the challenges it faces are inherently complex. Experiences in Belgium and abroad show that the impact on the city centre of Brussels will be significant at different levels: the quality of public space; housing and public services; local economy and employment; mobility, logistics and accessibility; and social and cultural activities. However, recent data and analyses are fragmented, non-existent or inaccessible for all stakeholders involved. Nevertheless, an urban project may only succeed when knowledge and expertise are gathered and shared, and used to support decision-making. Therefore, BSI - Brussels Centre Observatory (BSI-BCO) is monitoring this project closely. Previously published research is further developed in this synopsis [Portfolio#1]. Part 1 discusses the context of the project. Part 2 details the four main challenges based on our first observations. The synopsis concludes with concrete scenarios to improve the overall quality and management of the project.

The new pedestrian area in the centre of Brussels is one of the most important urban projects of the last decades. In 2015, the central traffic artery, Boulevard Anspach, was pedestrianised. The public space and the biggest metro stations must still be renovated. The implementation of this project and the challenges it faces are inherently complex. Experiences in Belgium and abroad show that the impact on the city centre of Brussels will be significant at different levels: the quality of public space; housing and public services; local economy and employment; mobility, logistics and accessibility; and social and cultural activities. However, recent data and analyses are fragmented, non-existent or inaccessible for all stakeholders involved. Nevertheless, an urban project may only succeed when knowledge and expertise are gathered and shared, and used to support decision-making. Therefore, BSI - Brussels Centre Observatory (BSI-BCO) is monitoring this project closely. Previously published research is further developed in this synopsis [Portfolio#1]. Part 1 discusses the context of the project. Part 2 details the four main challenges based on our first observations. The synopsis concludes with concrete scenarios to improve the overall quality and management of the project.

The new pedestrian area in the centre of Brussels is one of the most important urban projects of the last decades. In 2015, the central traffic artery, Boulevard Anspach, was pedestrianised. The public space and the biggest metro stations must still be renovated. The implementation of this project and the challenges it faces are inherently complex. Experiences in Belgium and abroad show that the impact on the city centre of Brussels will be significant at different levels: the quality of public space; housing and public services; local economy and employment; mobility, logistics and accessibility; and social and cultural activities. However, recent data and analyses are fragmented, non-existent or inaccessible for all stakeholders involved. Nevertheless, an urban project may only succeed when knowledge and expertise are gathered and shared, and used to support decision-making. Therefore, BSI - Brussels Centre Observatory (BSI-BCO) is monitoring this project closely. Previously published research is further developed in this synopsis [Portfolio#1]. Part 1 discusses the context of the project. Part 2 details the four main challenges based on our first observations. The synopsis concludes with concrete scenarios to improve the overall quality and management of the project.

No abstract available.

In 2019-2020, the Brussels Capital Region will be home to some 24 000 more students than there were in 2013-2014, in preschool, primary and secondary education. This growth generates additional needs in infrastructure, but also in teachers. An interuniversity research team from the Université Libre de Bruxelles, the Vrije Universiteit Brussel, the Université Saint-Louis and the Université catholique de Louvain have analysed the data available so as to have a clearer view of the Brussels perspective. The IBSA/BISA Cahier No 5, summarised in a Brussels Studies Fact Sheet, lays out their estimates of the number of teachers needed in 2019-2020.

In 2019-2020, the Brussels Capital Region will be home to some 24 000 more students than there were in 2013-2014, in preschool, primary and secondary education. This growth generates additional needs in infrastructure, but also in teachers. An interuniversity research team from the Université Libre de Bruxelles, the Vrije Universiteit Brussel, the Université Saint-Louis and the Université catholique de Louvain have analysed the data available so as to have a clearer view of the Brussels perspective. The IBSA/BISA Cahier No 5, summarised in a Brussels Studies Fact Sheet, lays out their estimates of the number of teachers needed in 2019-2020.

In 2019-2020, the Brussels Capital Region will be home to some 24 000 more students than there were in 2013-2014, in preschool, primary and secondary education. This growth generates additional needs in infrastructure, but also in teachers. An interuniversity research team from the Université Libre de Bruxelles, the Vrije Universiteit Brussel, the Université Saint-Louis and the Université catholique de Louvain have analysed the data available so as to have a clearer view of the Brussels perspective. The IBSA/BISA Cahier No 5, summarised in a Brussels Studies Fact Sheet, lays out their estimates of the number of teachers needed in 2019-2020.

In good times and in bad: The tumultuous relationship between the church and the organ - is divorce inevitable? Through the ages, a delicate relationship has existed between the church and the pipe organ. Since the 10th century, the organ established itself as a unique instrument in service of worship. This relationship was not always a steady one, and this article investigates the tumultuous affair between the two parties. In part one of the article, which is a historic perspective, the relationship is discussed by looking at different cultures and uses of the organ in the worship service. This gives a sense of when and how the relationship came into being and developed or deteriorated. In part two, the current situation in the Afrikaans Reformed service is explored by conducting several unstructured interviews with key role players in the theological and musical world of South Africa. In part three, the study ventures into speculating about the future of the organ in the worship service by briefly looking at the attitude of the organist and spirituality of the postmodern church goer. In essence, this article reflects on whether the marriage between church and music instrument is solid or on its way to the divorce court.Intradisciplinary and/or interdisciplinary implications: The relationship between organ and church has to be reconsidered. The use of the organ in the worship service has to be taken under scrutiny, and a new relationship agreement between the two partners has to be formulated.

What constitutes the functions and the essence of Pauline church leadership? How functional, relevant and useful is the huge amount of secular and religious� literature� published annually regarding leadership, for the church of Jesus Christ? In an effort to answer these and other questions, this essay studies portions of First and Second Corinthians, and comes to two conclusions. Firstly,� that� Pauline church leaders were characterised by service and� servanthood, and� secondly, that they also functioned as the mediators of pneumatological realities. Both of these dimentions function wholly within the paradigm of humility and dependance upon God, who is shown by Paul to be the source, as well as the focus of the superlative glory that characterises the ministry of the new covenant. The effects of the Pauline ministry functions simultaneously as the fruits, as well as the criteria of Pauline ministry in the new covenant.