Search

Objective: Get insight into excess mortality in the Rotterdam homeless population according to cause of death and changes in this mortality after introduction of social policies in Rotterdam, the Netherlands, in 2006., Design: Uncontrolled before-and-after study., Method: We included homeless adults who visited the Rotterdam shelter in 2001 and followed them for 10 years (2001-2010). We then linked the data of this cohort to Statistics Netherlands mortality figures. We calculated the shares of specific mortality causes in total mortality for the entire study period. We used the 'standardised mortality ratio' (SMR) to compare mortality in the homeless cohort of this period with mortality figures of the general Rotterdam population. In order to be able to compare the homeless death rates according to cause of death in the period before (2001-2005) and after introduction of social policy measures (2006-2010), the hazard ratio (HR) was calculated., Results: Our cohort consisted of 2130 homeless persons with a mean age of 40.3 years. The most important causes of death were unnatural death (26%; 95% CI: 21-32), cardiovascular diseases (22%; 17-27) and cancer (17%; 13-22). Suicide and murder together were responsible for 50% of the unnatural deaths. The largest differences in mortality in comparison with the Rotterdam population were those for unnatural death (SMR: 14.8; 95% CI: 11.5-18.7), infectious diseases (SMR: 10.0; 5.2-17.5) and psychiatric conditions (SMR: 7.7; 4.0-13.5). Mortality due to suicide or murder was significantly different for both study periods (HR: 0.45; 0.20-0.97)., Conclusion: Prevention of unnatural deaths among the homeless should be one of the priorities in homeless policy. Improvement of their living conditions may reduce the number of murders and suicides in this vulnerable group.

Objective: To estimate mortality due to chronic hepatitis B-virus (HBV) and hepatitis C-virus (HCV) infections in the Netherlands from 2002 to 2015., Design: A cross-sectional analysis based on cause-of-death statistics., Method: From Statistics Netherlands we obtained detailed data regarding the number of deaths per year in the following ICD-10 categories: chronic viral hepatitis; malignant neoplasm of the liver and intrahepatic bile ducts; fibrosis and cirrhosis of the liver; and alcoholic liver disease. We determined the population-attributable fractions (PAF) of HBV and HCV infections in mortality due to hepatocellular carcinoma (HCC) and cirrhosis of the liver, and added these to the recorded mortality from viral hepatitis in order to calculate total mortality. We used Dutch research as a basis for allocation to HCC, and a range of PAFs from 3 studies for cirrhosis. Poisson regression was used to assess mortality trends over time and any differences in demographic characteristics., Results: Around 500 Dutch people died annually of chronic viral hepatitis from 2002 to 2015, according to our 'middle' estimate; the 'lowest' estimate yields 340 and the 'highest' 600 people per year. The total mortality due to a chronic HBV and HCV infection did not change over time. The mortality for HCC due to viral hepatitis increased slightly over time and the mortality for cirrhosis decreased slightly. HCC mortality due to viral hepatitis was higher in Dutch people of non-western origin., Conclusion: Mortality from chronic viral hepatitis is mostly the result of cirrhosis of the liver and HCC. About 500 persons died annually from 2002 to 2015 from causes linked to viral hepatitis.

Life expectancy in western countries has increased continuously over recent years. The issue at stake is if this rise includes healthy years. The answer depends on the health indicator used, e.g., perceived health, disability, or cognitive impairment. A study by Jagger et al. (2016) provides evidence for an increase in life expectancy without cognitive impairment and an absolute compression of cognitive impairment between 1991 and 2011. Information on life expectancy without cognitive impairment is not yet available for the Netherlands. Similar to England, Dutch trends in life expectancy in excellent or good self-perceived health and in life expectancy without severe disability are favourable, although less pronouncedly so. Dutch and English data suggest that the additional years lived by the population are at least partly spent in good health.

There is an urgent need for strategies that alleviate the societal consequences of population ageing. A possible strategy is aiming for compression of morbidity. Some of the initial conditions for a compression of morbidity have been invalidated. This is, the life expectancy has shown a much stronger increase than was expected and the modal age at death has exceeded the age of 85. Additionally, trend studies have found no consistent evidence for a compression of morbidity. At the department of Public Health, we aim at identifying entry-points for a compression. For example, an analysis was performed on potential contributions of changes in exposure to life style factors (smoking, hypertension, physical inactivity and overweight/obesity) to compression of cardiovascular disease, using multi-state life tables with data from the Framingham Heart Study. It was shown that smoking and physical inactivity increased the incidence of cardiovascular disease, as well as mortality with and without cardiovascular disease. Hypertension and overweight mainly increased the incidence of cardiovascular disease and were associated with a shorter lifespan and more years with cardiovascular disease. Interventions on the latter risk factors will therefore increase the life expectancy, but will also result in a compression of morbidity. For policymakers and researchers it is important to find a mix of interventions that lead to a comparable overall effect.