1. Drawing up the balance sheet after a yea
- Subjects
leflunomide ,rheumatoid arthritis ,hydroxychloroquine ,drug safety ,adult ,article ,drug response ,gastrointestinal symptom ,salazosulfapyridine ,major clinical study ,methotrexate ,drug efficacy ,skin manifestation ,aged ,drug withdrawal ,outpatient ,incidence ,treatment outcome ,human ,Netherlands - Abstract
This article evaluates the efficacy, safety, incidence and reason of withdrawal of leflunomide in an outpatient population in Friesland (the Netherlands) with rheumatoid arthritis in a setting of care-as-usual. A large part of the population showed a good or moderate response on leflunomide. Adverse events were generally mild. Most frequently reported were gastrointestinal and dermal events. No potential risk factors for leflunomide withdrawal were found.
- Published
- 2001