1. [Drowning-induced hyperfibrinolytic disseminated intravascular coagulation].
- Author
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Hattesen AL, Berg HK, Folkersen L, and Hvas AM
- Subjects
- Antifibrinolytic Agents therapeutic use, Disseminated Intravascular Coagulation diagnosis, Disseminated Intravascular Coagulation drug therapy, Disseminated Intravascular Coagulation physiopathology, Humans, Near Drowning physiopathology, Thrombelastography, Tranexamic Acid therapeutic use, Disseminated Intravascular Coagulation etiology, Near Drowning complications
- Abstract
This article summarizes the current knowledge of drowning-induced hyperfibrinolytic disseminated intravascular coagulation. Drowning induces respiratory failure with ensuing cardiac arrest, hypoxaemia and ischaemia. A coagulopathy is induced by ischaemia, acidosis and hypothermia, and clinically the patient develops uncontrolled bleeding due to hyperfibrinolysis. A rapid diagnostic approach is required to recognize this hyperfibrinolytic state, since initiation of treatment with antifibrinolytics and fibrinogen concentrate may bring this life-threatening condition to cessation.
- Published
- 2017